The effect of rowing on endothelial function and insulin action in healthy controls and in patients with type 2 diabetes
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Patients with type 2 diabetes (T2DM) have an increased risk for cardiovascular disease. We examined the effects of 8 weeks of home-based rowing training (heart rate corresponding to 65-70% of VO(2 peak) ) on endothelial function and glucose clearance (local and systemic effects) in male subjects with T2DM (n=9) and matched controls (n=8). Before and after training (30 min every other day), all subjects underwent sequential graded brachial artery infusions of non-insulin vasodilators (acetylcholine; sodium nitroprusside; adenosine). Forearm blood flow was improved by training in controls (without and with insulin: P=0.003 and 0.05, respectively) but not in subjects with T2DM. Likewise, whole body glucose clearance increased in response to training in controls (P=0.05) but not in T2DM. However, in both groups, the capacity for local forearm glucose extraction (controls: P=0.001; T2DM: P=0.002) and clearance (controls: P
Originalsprog | Engelsk |
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Tidsskrift | Scandinavian Journal of Medicine & Science in Sports Online |
Vol/bind | 21 |
Udgave nummer | 3 |
Sider (fra-til) | 420-30 |
Antal sider | 11 |
ISSN | 1600-0838 |
DOI | |
Status | Udgivet - 1 jun. 2011 |
ID: 33815938