The association between sleep duration and detailed measures of obesity: A cross sectional analysis in the ADDITION-PRO study

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  • Mie M. Andersen
  • Tinne Laurberg
  • Anne Louise Bjerregaard
  • Annelli Sandbæk
  • Søren Brage
  • Dorte Vistisen
  • Quist, Jonas Salling
  • Jens M. Bruun
  • Daniel R. Witte

Background: Sleep duration is associated with BMI and waist circumference. However, less is known about whether sleep duration affects different measurements of obesity differently. Objective: To investigate the association between sleep duration and different measures of obesity. Methods: In this cross-sectional analysis 1309, Danish, older adults (55% men) completed at least 3 days of wearing a combined accelerometer and heart rate-monitor for assessing sleep duration (hours/night) within self-reported usual bedtime. Participants underwent anthropometry and ultrasonography to assess BMI, waist circumference, visceral fat, subcutaneous fat, and fat percentage. Linear regression analyses examined the associations between sleep duration and obesity-related outcomes. Results: Sleep duration was inversely associated with all obesity-related outcomes, except visceral-/subcutaneous-fat-ratio. After multivariate adjustment the magnitude of associations became stronger and statistically significant for all outcomes except visceral-/subcutaneous-fat-ratio, and subcutaneous fat in women. The associations with BMI and waist circumference demonstrated the strongest associations, when comparing standardized regression coefficients. Conclusions: Shorter sleep duration were associated with higher obesity across all outcomes except visceral-/subcutaneous-fat-ratio. No specifically salient associations with local or central obesity were observed. Results suggest that poor sleep duration and obesity correlate, however, further research is needed to conclude on beneficial effects of sleep duration regarding health and weight loss.

OriginalsprogEngelsk
TidsskriftObesity Science and Practice
Vol/bind9
Udgave nummer3
Sider (fra-til) 226-234
Antal sider9
ISSN2055-2238
DOI
StatusUdgivet - 2023

Bibliografisk note

Funding Information:
The authors acknowledge the ADDITION‐PRO study centers and are most grateful to the support staff and the participants for their contribution in the study. Data from the ADDITION‐PRO study are not publicly available. Data can be made accessible upon reasonable request, with approval of the ADDITION‐Denmark Steering committee and under a collaboration agreement. The study protocol is publicly available. The ADDITION‐Denmark study was supported by the National Health Services in the former counties of Copenhagen, Aarhus, Ringkøbing, Ribe, and Southern Jutland in Denmark; the Danish Council for Strategic Research; the Danish Research Foundation for General Practice; Novo Nordisk Foundation; the Danish Centre for Evaluation and Health Technology Assessment; the Diabetes Fund of the National Board of Health; the Danish Medical Research Council; and the Aarhus University Research Foundation. Additionally, the ADDITION‐PRO study was funded by an unrestricted grant from the European Foundation for the Study of Diabetes/Pfizer for Research into Cardiovascular Disease Risk Reduction in Patients with Diabetes (74550801), the Danish Council for Strategic Research, and internal research and equipment funds from Steno Diabetes Center Copenhagen. Anne‐Louise Bjerregaard additionally received a scholarship funding from the Capital Region of Denmark. The Steno Diabetes Centers in Aarhus and Copenhagen receive part of their core funding from unrestricted grants from the Novo Nordisk Foundation.

Funding Information:
Dorte Vistisen and Daniel R. Witte own shares in Novo Nordisk A/S. Daniel R. Witte has received funding from Novo Nordisk A/S. No other potential conflicts of interest relevant to this article were reported. The ADDITION‐Denmark Steering Committee consists of Dorte Vistisen, Daniel R. Witte and Annelli Sandbæk.

Publisher Copyright:
© 2022 The Authors. Obesity Science & Practice published by World Obesity and The Obesity Society and John Wiley & Sons Ltd.

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