Glucagon like peptide-1-induced glucose metabolism in differentiated human muscle satellite cells is attenuated by hyperglycemia
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Glucagon like peptide-1 (GLP-1) stimulates insulin secretion from the pancreas but also has extra-pancreatic effects. GLP-1 may stimulate glucose uptake in cultured muscle cells but the mechanism is not clearly defined. Furthermore, while the pancreatic effects of GLP-1 are glucose-dependent, the glucose-dependency of its extra-pancreatic effects has not been examined.
Originalsprog | Engelsk |
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Tidsskrift | P L o S One |
Vol/bind | 7 |
Udgave nummer | 8 |
Sider (fra-til) | e44284 |
ISSN | 1932-6203 |
DOI | |
Status | Udgivet - 2012 |
ID: 48551688