Danish premature birth rates during the COVID-19 lockdown
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Danish premature birth rates during the COVID-19 lockdown. / Hedermann, Gitte; Hedley, Paula Louise; Bækvad-Hansen, Marie; Hjalgrim, Henrik; Rostgaard, Klaus; Poorisrisak, Porntiva; Breindahl, Morten; Melbye, Mads; Hougaard, David M.; Christiansen, Michael; Lausten-Thomsen, Ulrik.
I: Archives of Disease in Childhood: Fetal and Neonatal Edition, Bind 106, 2021, s. F93-F95.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Danish premature birth rates during the COVID-19 lockdown
AU - Hedermann, Gitte
AU - Hedley, Paula Louise
AU - Bækvad-Hansen, Marie
AU - Hjalgrim, Henrik
AU - Rostgaard, Klaus
AU - Poorisrisak, Porntiva
AU - Breindahl, Morten
AU - Melbye, Mads
AU - Hougaard, David M.
AU - Christiansen, Michael
AU - Lausten-Thomsen, Ulrik
PY - 2021
Y1 - 2021
N2 - To explore the impact of COVID-19 lockdown on premature birth rates in Denmark, a nationwide register-based prevalence proportion study was conducted on all 31 180 live singleton infants born in Denmark between 12 March and 14 April during 2015-2020. The distribution of gestational ages (GAs) was significantly different (p=0.004) during the lockdown period compared with the previous 5 years and was driven by a significantly lower rate of extremely premature children during the lockdown compared with the corresponding mean rate for the same dates in the previous years (OR 0.09, 95% CI 0.01 to 0.40, p<0.001). No significant difference between the lockdown and previous years was found for other GA categories. The reasons for this decrease are unclear. However, the lockdown has provided a unique opportunity to examine possible factors related to prematurity. Identification of possible causal mechanisms might stimulate changes in clinical practice.
AB - To explore the impact of COVID-19 lockdown on premature birth rates in Denmark, a nationwide register-based prevalence proportion study was conducted on all 31 180 live singleton infants born in Denmark between 12 March and 14 April during 2015-2020. The distribution of gestational ages (GAs) was significantly different (p=0.004) during the lockdown period compared with the previous 5 years and was driven by a significantly lower rate of extremely premature children during the lockdown compared with the corresponding mean rate for the same dates in the previous years (OR 0.09, 95% CI 0.01 to 0.40, p<0.001). No significant difference between the lockdown and previous years was found for other GA categories. The reasons for this decrease are unclear. However, the lockdown has provided a unique opportunity to examine possible factors related to prematurity. Identification of possible causal mechanisms might stimulate changes in clinical practice.
KW - epidemiology
KW - neonatology
U2 - 10.1136/archdischild-2020-319990
DO - 10.1136/archdischild-2020-319990
M3 - Journal article
C2 - 32788391
AN - SCOPUS:85091885160
VL - 106
SP - F93-F95
JO - Archives of Disease in Childhood
JF - Archives of Disease in Childhood
SN - 0003-9888
ER -
ID: 252300400