Chronic Cranial Windows for Long Term Multimodal Neurovascular Imaging in Mice
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Chronic Cranial Windows for Long Term Multimodal Neurovascular Imaging in Mice. / Kılıç, Kıvılcım; Desjardins, Michèle; Tang, Jianbo; Thunemann, Martin; Sunil, Smrithi; Erdener, Şefik Evren; Postnov, Dmitry D.; Boas, David A.; Devor, Anna.
I: Frontiers in Physiology, Bind 11, 612678, 2021.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Chronic Cranial Windows for Long Term Multimodal Neurovascular Imaging in Mice
AU - Kılıç, Kıvılcım
AU - Desjardins, Michèle
AU - Tang, Jianbo
AU - Thunemann, Martin
AU - Sunil, Smrithi
AU - Erdener, Şefik Evren
AU - Postnov, Dmitry D.
AU - Boas, David A.
AU - Devor, Anna
N1 - Publisher Copyright: © Copyright © 2021 Kılıç, Desjardins, Tang, Thunemann, Sunil, Erdener, Postnov, Boas and Devor.
PY - 2021
Y1 - 2021
N2 - Chronic cranial windows allow for longitudinal brain imaging experiments in awake, behaving mice. Different imaging technologies have their unique advantages and combining multiple imaging modalities offers measurements of a wide spectrum of neuronal, glial, vascular, and metabolic parameters needed for comprehensive investigation of physiological and pathophysiological mechanisms. Here, we detail a suite of surgical techniques for installation of different cranial windows targeted for specific imaging technologies and their combination. Following these techniques and practices will yield higher experimental success and reproducibility of results.
AB - Chronic cranial windows allow for longitudinal brain imaging experiments in awake, behaving mice. Different imaging technologies have their unique advantages and combining multiple imaging modalities offers measurements of a wide spectrum of neuronal, glial, vascular, and metabolic parameters needed for comprehensive investigation of physiological and pathophysiological mechanisms. Here, we detail a suite of surgical techniques for installation of different cranial windows targeted for specific imaging technologies and their combination. Following these techniques and practices will yield higher experimental success and reproducibility of results.
KW - awake
KW - chronic
KW - imaging
KW - mice
KW - multimodal
KW - neural
KW - vascular
UR - http://www.scopus.com/inward/record.url?scp=85100557686&partnerID=8YFLogxK
U2 - 10.3389/fphys.2020.612678
DO - 10.3389/fphys.2020.612678
M3 - Journal article
C2 - 33551837
AN - SCOPUS:85100557686
VL - 11
JO - Frontiers in Physiology
JF - Frontiers in Physiology
SN - 1664-042X
M1 - 612678
ER -
ID: 279430942