Bronchial histamine challenge. A combined interrupter-dosimeter method compared with a standard method.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Standard

Bronchial histamine challenge. A combined interrupter-dosimeter method compared with a standard method. / Pavlovic, M; Holstein-Rathlou, N H; Madsen, F; Svendsen, U G; Weeke, B.

I: Allergy. European Journal of Allergy and Clinical Immunology, Bind 40, Nr. 8, 1985, s. 574-9.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Pavlovic, M, Holstein-Rathlou, NH, Madsen, F, Svendsen, UG & Weeke, B 1985, 'Bronchial histamine challenge. A combined interrupter-dosimeter method compared with a standard method.', Allergy. European Journal of Allergy and Clinical Immunology, bind 40, nr. 8, s. 574-9.

APA

Pavlovic, M., Holstein-Rathlou, N. H., Madsen, F., Svendsen, U. G., & Weeke, B. (1985). Bronchial histamine challenge. A combined interrupter-dosimeter method compared with a standard method. Allergy. European Journal of Allergy and Clinical Immunology, 40(8), 574-9.

Vancouver

Pavlovic M, Holstein-Rathlou NH, Madsen F, Svendsen UG, Weeke B. Bronchial histamine challenge. A combined interrupter-dosimeter method compared with a standard method. Allergy. European Journal of Allergy and Clinical Immunology. 1985;40(8):574-9.

Author

Pavlovic, M ; Holstein-Rathlou, N H ; Madsen, F ; Svendsen, U G ; Weeke, B. / Bronchial histamine challenge. A combined interrupter-dosimeter method compared with a standard method. I: Allergy. European Journal of Allergy and Clinical Immunology. 1985 ; Bind 40, Nr. 8. s. 574-9.

Bibtex

@article{a029b9a0abf111ddb5e9000ea68e967b,
title = "Bronchial histamine challenge. A combined interrupter-dosimeter method compared with a standard method.",
abstract = "We compared the provocative concentration (PC) values obtained by two different methods of performing bronchial histamine challenge. One test was done on an APTA, an apparatus which allows simultaneous provocation with histamine and measurement of airway resistance (Rtot) by the interrupter method. The second test was a conventional tidal breathing method, with measurement of the FEV1. There was a high correlation between the PC20-FEV1 and the PC30-, PC40- and PC50-Rtot values. The correlation coefficients were 0.85, 0.71 and 0.70 (P less than 0.05) respectively. We further tested the reproducibility of the histamine challenge done on the APTA. When the PC30-Rtot values were compared, a correlation coefficient of 0.56 (NS) was found. For the PC40- and PC50-Rtot values the correlation coefficients were 0.65 (P less than 0.05) and 0.70 (P less than 0.02) respectively. We conclude that the APTA is useful for routine bronchial histamine challenge when 40-50% increase in basal Rtot is used as endpoint.",
author = "M Pavlovic and Holstein-Rathlou, {N H} and F Madsen and Svendsen, {U G} and B Weeke",
note = "Keywords: Adolescent; Adult; Aged; Asthma; Bronchial Provocation Tests; Female; Forced Expiratory Volume; Histamine; Humans; Male; Middle Aged; Plethysmography; Rhinitis, Allergic, Perennial",
year = "1985",
language = "English",
volume = "40",
pages = "574--9",
journal = "Allergy: European Journal of Allergy and Clinical Immunology",
issn = "0105-4538",
publisher = "Wiley Online",
number = "8",

}

RIS

TY - JOUR

T1 - Bronchial histamine challenge. A combined interrupter-dosimeter method compared with a standard method.

AU - Pavlovic, M

AU - Holstein-Rathlou, N H

AU - Madsen, F

AU - Svendsen, U G

AU - Weeke, B

N1 - Keywords: Adolescent; Adult; Aged; Asthma; Bronchial Provocation Tests; Female; Forced Expiratory Volume; Histamine; Humans; Male; Middle Aged; Plethysmography; Rhinitis, Allergic, Perennial

PY - 1985

Y1 - 1985

N2 - We compared the provocative concentration (PC) values obtained by two different methods of performing bronchial histamine challenge. One test was done on an APTA, an apparatus which allows simultaneous provocation with histamine and measurement of airway resistance (Rtot) by the interrupter method. The second test was a conventional tidal breathing method, with measurement of the FEV1. There was a high correlation between the PC20-FEV1 and the PC30-, PC40- and PC50-Rtot values. The correlation coefficients were 0.85, 0.71 and 0.70 (P less than 0.05) respectively. We further tested the reproducibility of the histamine challenge done on the APTA. When the PC30-Rtot values were compared, a correlation coefficient of 0.56 (NS) was found. For the PC40- and PC50-Rtot values the correlation coefficients were 0.65 (P less than 0.05) and 0.70 (P less than 0.02) respectively. We conclude that the APTA is useful for routine bronchial histamine challenge when 40-50% increase in basal Rtot is used as endpoint.

AB - We compared the provocative concentration (PC) values obtained by two different methods of performing bronchial histamine challenge. One test was done on an APTA, an apparatus which allows simultaneous provocation with histamine and measurement of airway resistance (Rtot) by the interrupter method. The second test was a conventional tidal breathing method, with measurement of the FEV1. There was a high correlation between the PC20-FEV1 and the PC30-, PC40- and PC50-Rtot values. The correlation coefficients were 0.85, 0.71 and 0.70 (P less than 0.05) respectively. We further tested the reproducibility of the histamine challenge done on the APTA. When the PC30-Rtot values were compared, a correlation coefficient of 0.56 (NS) was found. For the PC40- and PC50-Rtot values the correlation coefficients were 0.65 (P less than 0.05) and 0.70 (P less than 0.02) respectively. We conclude that the APTA is useful for routine bronchial histamine challenge when 40-50% increase in basal Rtot is used as endpoint.

M3 - Journal article

C2 - 4091233

VL - 40

SP - 574

EP - 579

JO - Allergy: European Journal of Allergy and Clinical Immunology

JF - Allergy: European Journal of Allergy and Clinical Immunology

SN - 0105-4538

IS - 8

ER -

ID: 8440502