Department of Biomedical Sciences

Endocrinology and Metabolism

We study endocrinology and metabolism in health and disease towards novel approaches for prevention, diagnostics and treatment.

We study appetite regulation, immune-metabolism and weight loss physiology towards effective and personalized treatment of obesity and its co-morbidities. In the area of diabetes we address the genetic, molecular and cellular basis for stimulation of beta and alpha cell growth, differentiation, hormone secretion, insulin resistance, incretin effects of gut hormones and pharmacological treatment.

We also explore the effects of gut hormones on function and metabolism of bone, intestine, liver and other tissues towards novel treatments of osteoporosis, pulmonary, intestinal and fatty liver diseases.

New life style interventions are developed and tested for their health enhancing effects and potential for implementation in everyday life of the citizens and in the health and care sector.

For more information on the topics and methods, please visit the group sites of our theme members.

Billestrup Group

We use a number of in vitro and in vivo models systems to study the molecular and cellular basis for stimulation of beta cell growth and differentiation.

Desler Group

In Desler Group we investigate aging at the molecular level and its link to age-related diseases. This is done using 2D and advanced 3D cell culture models alongside biopsies collected from human cohorts. Our goal is to…

Fritzen Group

The main objective is to deepen our understanding of the molecular regulation of lipid metabolism. We are at the moment particularly interested in identifying molecular mechanisms behind health effects of lipids and…

Grevengoed Group

We focuse on determining biological functions of different fats, such as omega-3 fatty acids, and their metabolites in cardiometabolic disease. Our work spans biochemistry and physiology to understand the necessity and…

Hartmann Group

We investigate the mechanism by which hormones secreted from the intestine affect bone remodelling. Using cell, animal and human studies, we increase our understanding of intestinal and bone physiology, and identify new…

Holst Group

In our group, we combine laboratory experiments with clinical studies in order to understand the functional challenges of obesity and diabetes, and to provide new principles for improved therapy of these conditions.

Jensen Group

We dissect how dietary factors affect gut barrier integrity and host-microbe interactions at the onset, prevention, and treatment of chronic inflammatory diseases.

Kissow Group

Our main purpose of the group is to establish knowledge leading the way to improved treatment of patients suffering from intestinal diseases such as inflammatory bowel diseases or chemotherapy induced mucositis.

Peter Holst Group

The group focuses on endogenous retroviruses from human and model organisms as key players in metabolic stress and the application of the immune to eliminate harmful cells expressing pathogenic genes of retroviral…

Stallknecht Group

In Act4Life we develop, carry out and publish research elucidating the mechanisms behind the health-enhancing effects of physical activity. We also investigate how to best implement physical activity in daily life.

Sylow Group

Our research focuses on delineating the molecular causes of muscle wasting and associated metabolic dysfunctions. We are trying to identify mechanisms that, at the molecular level, might regulate muscle mass, function,…

Torekov Group

In The Clinical Translational Metabolism Group we have the overall goal of creating evidence of how to obtain healthy weight throughout life. Our vision is to implement this evidence to prevent obesity-related disease…