Novel synthetic route to the C-nucleoside, 2-deoxy benzamide riboside
Research output: Contribution to journal › Journal article › Research › peer-review
2-Deoxy-C-nucleosides are a subcategory of C-nucleosides that has not been explored extensively, largely because the synthesis is less facile. Flexible synthetic procedures giving access to 2-deoxy-C-nucleosides are therefore of interest. To exemplify the versatility and highlight the limitations of a synthetic route recently developed to that effect, the first synthesis of 2-deoxy benzamide riboside is reported. Biological properties of this novel C-nucleoside are also discussed.
Original language | English |
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Journal | Bioorganic and Medicinal Chemistry Letters |
Volume | 22 |
Issue number | 16 |
Pages (from-to) | 5204-5207 |
Number of pages | 4 |
ISSN | 0960-894X |
DOIs | |
Publication status | Published - 15 Aug 2012 |
- Benzamide riboside, C-Nucleoside, Inosine monophosphate dehydrogenase, Intramolecular cyclisation, Nicotinamide adenine dinucleotide
Research areas
ID: 220855816