NNMT: A Bad Actor in Fat Makes Good in Liver

Research output: Contribution to journalEditorialResearchpeer-review

High adipose expression of NNMT, an enzyme that converts nicotinamide to 1-methyl-nicotinamide, correlates with adiposity. Though murine NNMT knockdown in fat and liver prevents weight gain on high-fat diet, Hong et al. (2015) now show that high hepatic expression of NNMT improves lipid parameters via SIRT1 stabilization.

Original languageEnglish
JournalCell Metabolism
Volume22
Issue number2
Pages (from-to)200-201
Number of pages2
ISSN1550-4131
DOIs
Publication statusPublished - 4 Aug 2015

ID: 220855659