Bringing Radiotracing to Titanium-Based Antineoplastics: Solid Phase Radiosynthesis, PET and ex Vivo Evaluation of Antitumor Agent [45Ti](salan)Ti(dipic)
Research output: Contribution to journal › Journal article › Research › peer-review
We present a novel solid-phase based 45Ti radiolabeling methodology and the implementation of 45Ti-PET in titanium-based antineoplastics using the showcase compound [45Ti](salan)Ti(dipic). This development is intended to allow elucidation of the biodistribution and pharmacokinetics of promising new Ti-based therapeutics.
| Original language | English |
|---|---|
| Journal | Journal of Medicinal Chemistry |
| Volume | 58 |
| Issue number | 18 |
| Pages (from-to) | 7591-7595 |
| Number of pages | 5 |
| ISSN | 0022-2623 |
| DOIs | |
| Publication status | Published - 24 Sep 2015 |
ID: 147663189