Bringing Radiotracing to Titanium-Based Antineoplastics: Solid Phase Radiosynthesis, PET and ex Vivo Evaluation of Antitumor Agent [45Ti](salan)Ti(dipic)

Research output: Contribution to journalJournal articleResearchpeer-review

Standard

Bringing Radiotracing to Titanium-Based Antineoplastics : Solid Phase Radiosynthesis, PET and ex Vivo Evaluation of Antitumor Agent [45Ti](salan)Ti(dipic). / Severin, Gregory W.; Nielsen, Carsten H.; Jensen, Andreas I.; Fonslet, Jesper; Kjær, Andreas; Zhuravlev, Fedor.

In: Journal of Medicinal Chemistry, Vol. 58, No. 18, 24.09.2015, p. 7591-7595.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Severin, GW, Nielsen, CH, Jensen, AI, Fonslet, J, Kjær, A & Zhuravlev, F 2015, 'Bringing Radiotracing to Titanium-Based Antineoplastics: Solid Phase Radiosynthesis, PET and ex Vivo Evaluation of Antitumor Agent [45Ti](salan)Ti(dipic)', Journal of Medicinal Chemistry, vol. 58, no. 18, pp. 7591-7595. https://doi.org/10.1021/acs.jmedchem.5b01167

APA

Severin, G. W., Nielsen, C. H., Jensen, A. I., Fonslet, J., Kjær, A., & Zhuravlev, F. (2015). Bringing Radiotracing to Titanium-Based Antineoplastics: Solid Phase Radiosynthesis, PET and ex Vivo Evaluation of Antitumor Agent [45Ti](salan)Ti(dipic). Journal of Medicinal Chemistry, 58(18), 7591-7595. https://doi.org/10.1021/acs.jmedchem.5b01167

Vancouver

Severin GW, Nielsen CH, Jensen AI, Fonslet J, Kjær A, Zhuravlev F. Bringing Radiotracing to Titanium-Based Antineoplastics: Solid Phase Radiosynthesis, PET and ex Vivo Evaluation of Antitumor Agent [45Ti](salan)Ti(dipic). Journal of Medicinal Chemistry. 2015 Sep 24;58(18):7591-7595. https://doi.org/10.1021/acs.jmedchem.5b01167

Author

Severin, Gregory W. ; Nielsen, Carsten H. ; Jensen, Andreas I. ; Fonslet, Jesper ; Kjær, Andreas ; Zhuravlev, Fedor. / Bringing Radiotracing to Titanium-Based Antineoplastics : Solid Phase Radiosynthesis, PET and ex Vivo Evaluation of Antitumor Agent [45Ti](salan)Ti(dipic). In: Journal of Medicinal Chemistry. 2015 ; Vol. 58, No. 18. pp. 7591-7595.

Bibtex

@article{bf7af1fa34bd4ecd907f103deddcd10e,
title = "Bringing Radiotracing to Titanium-Based Antineoplastics: Solid Phase Radiosynthesis, PET and ex Vivo Evaluation of Antitumor Agent [45Ti](salan)Ti(dipic)",
abstract = "We present a novel solid-phase based 45Ti radiolabeling methodology and the implementation of 45Ti-PET in titanium-based antineoplastics using the showcase compound [45Ti](salan)Ti(dipic). This development is intended to allow elucidation of the biodistribution and pharmacokinetics of promising new Ti-based therapeutics.",
author = "Severin, {Gregory W.} and Nielsen, {Carsten H.} and Jensen, {Andreas I.} and Jesper Fonslet and Andreas Kj{\ae}r and Fedor Zhuravlev",
year = "2015",
month = sep,
day = "24",
doi = "10.1021/acs.jmedchem.5b01167",
language = "English",
volume = "58",
pages = "7591--7595",
journal = "Journal of Medicinal Chemistry",
issn = "0022-2623",
publisher = "American Chemical Society",
number = "18",

}

RIS

TY - JOUR

T1 - Bringing Radiotracing to Titanium-Based Antineoplastics

T2 - Solid Phase Radiosynthesis, PET and ex Vivo Evaluation of Antitumor Agent [45Ti](salan)Ti(dipic)

AU - Severin, Gregory W.

AU - Nielsen, Carsten H.

AU - Jensen, Andreas I.

AU - Fonslet, Jesper

AU - Kjær, Andreas

AU - Zhuravlev, Fedor

PY - 2015/9/24

Y1 - 2015/9/24

N2 - We present a novel solid-phase based 45Ti radiolabeling methodology and the implementation of 45Ti-PET in titanium-based antineoplastics using the showcase compound [45Ti](salan)Ti(dipic). This development is intended to allow elucidation of the biodistribution and pharmacokinetics of promising new Ti-based therapeutics.

AB - We present a novel solid-phase based 45Ti radiolabeling methodology and the implementation of 45Ti-PET in titanium-based antineoplastics using the showcase compound [45Ti](salan)Ti(dipic). This development is intended to allow elucidation of the biodistribution and pharmacokinetics of promising new Ti-based therapeutics.

U2 - 10.1021/acs.jmedchem.5b01167

DO - 10.1021/acs.jmedchem.5b01167

M3 - Journal article

C2 - 26312993

VL - 58

SP - 7591

EP - 7595

JO - Journal of Medicinal Chemistry

JF - Journal of Medicinal Chemistry

SN - 0022-2623

IS - 18

ER -

ID: 147663189