Bringing Radiotracing to Titanium-Based Antineoplastics: Solid Phase Radiosynthesis, PET and ex Vivo Evaluation of Antitumor Agent [45Ti](salan)Ti(dipic)
Research output: Contribution to journal › Journal article › Research › peer-review
We present a novel solid-phase based 45Ti radiolabeling methodology and the implementation of 45Ti-PET in titanium-based antineoplastics using the showcase compound [45Ti](salan)Ti(dipic). This development is intended to allow elucidation of the biodistribution and pharmacokinetics of promising new Ti-based therapeutics.
Original language | English |
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Journal | Journal of Medicinal Chemistry |
Volume | 58 |
Issue number | 18 |
Pages (from-to) | 7591-7595 |
Number of pages | 5 |
ISSN | 0022-2623 |
DOIs | |
Publication status | Published - 24 Sep 2015 |
ID: 147663189