Thomas Mandrup-Poulsen

Thomas Mandrup-Poulsen

Professor


  1. 2008
  2. Published

    The Faroese, a genetic isolate with a strong founder effect, allows the identification of Type 1 diabetes susceptibility regions

    Nolsoe, R., Roin, J., Deckert, M., Bergholdt, R., Kelly, J., Brorsson, C., Harley, J., Olsen, S., Pociot, Flemming & Mandrup-Poulsen, Thomas, 2008, In: Clinical Immunology. 127, Suppl. S, p. S105-S105

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    The imidazoline RX871024 induces death of proliferating insulin-secreting cells by activation of c-jun N-terminal kinase

    Zaitseva, I. I., Storling, J., Mandrup-Poulsen, Thomas, Berggren, P. O. & Zaitsev, S. V., 2008, In: Cellular and Molecular Life Sciences. 65, 7-8, p. 1248-1255 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    The role of NCAM signaling in the pancreatic beta-cell

    Grunnet, L. G., Storling, J., Heding, P., Li, S., Berezin, V., Saldeen, J., Billestrup, N., Bock, E. & Mandrup-Poulsen, Thomas, 2008, In: FEBS Journal. 275, Suppl. 1

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    The use of interleukin-1-receptor antagonists in the treatment of diabetes mellitus.

    Donath, M. Y. & Mandrup-Poulsen, Thomas, 2008, In: Nature Clinical Practice Endocrinology & Metabolism. 4, 5, p. 240-1 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. 2007
  7. Published

    Inhibition of histone deacetylases prevents cytokine-induced toxicity in beta cells

    Larsen, L., Tonnesen, M., Ronn, S. G., Størling, Joachim, Jørgensen, S., Mascagni, P., Dinarello, C. A., Billestrup, Nils & Mandrup-Poulsen, Thomas, Apr 2007, In: Diabetologia. 50, 4, p. 779-89 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Association of immune mediators at diagnosis of Type 1 diabetes with later clinical remission

    Schloot, N. C., Hanifi-Moghaddam, P., Aabenhus-Andersen, N., Alizadeh, B. Z., Saha, M. T., Knip, M., Devendra, D., Wilkin, T., Bonifacio, E., Roep, B. O., Kolb, H. & Mandrup-Poulsen, Thomas, 2007, In: Diabetic Medicine. 24, 5, p. 512-520 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Cytokines and beta-cell biology: from concept to clinical translation

    Donath, M. Y., Storling, J., Berchtold, L. A., Billestrup, N. & Mandrup-Poulsen, Thomas, 2007, In: Endocrine Reviews. 29, 3, p. 334-50 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Diabetes and suppressors of cytokine signaling proteins.

    Rønn, S. G., Billestrup, N. & Mandrup-Poulsen, Thomas, 2007, In: Diabetes. 56, 2, p. 541-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Glutaminsyre-decarboxylase-antistoffer og diabetes.

    Mandrup-Poulsen, Thomas, 2007, In: Ugeskrift for læger. 169, 4, p. 300-4 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Inhibition of histone deacetylases prevents cytokine-induced toxicity in beta cells

    Larsen, L., Tonnesen, M. F., Ronn, S. G., Storling, J., Jørgensen, S., Mascagni, P., Dinarello, C. A., Billestrup, N. & Mandrup-Poulsen, Thomas, 2007, In: Diabetologia. 50, 4, p. 779-789 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Interleukin-1 receptorantagonistbehandling af patienter med type 2-diabetes--sekundaerpublikation.

    Larsen, C. M., Faulenbach, M., Vaag, Allan, Vølund, A., Ehses, J., Seifert, B., Mandrup-Poulsen, Thomas & Donath, M., 2007, In: Ugeskrift for læger. 169, 45, p. 3868-71 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Interleukin-1-receptor antagonist in type 2 diabetes mellitus - Reply

    Mandrup-Poulsen, Thomas, Seifert, B. & Donath, M. Y., 2007, In: New England Journal of Medicine. 357, 3, p. 303-303

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Interleukin-1-receptor antagonist in type 2 diabetes mellitus.

    Larsen, C. M., Faulenbach, M., Vaag, Allan, Vølund, A., Ehses, J. A., Seifert, B., Mandrup-Poulsen, Thomas & Donath, M. Y., 2007, In: New England Journal of Medicine. 356, 15, p. 1517-26 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Lost in translation

    Frank, L. & Mandrup-Poulsen, Thomas, 2007, In: Weekendavisen. 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    The Fas pathway is involved in pancreatic beta cell secretory function.

    Schumann, D. M., Maedler, K., Franklin, I., Konrad, D., Størling, J., Böni-Schnetzler, M., Gjinovci, A., Kurrer, M. O., Gauthier, B. R., Bosco, D., Andres, A., Berney, T., Greter, M., Becher, B., Chervonsky, A. V., Halban, P. A., Mandrup-Poulsen, Thomas, Wollheim, C. B. & Donath, M. Y., 2007, In: Proceedings of the National Academy of Science of the United States of America. 104, 8, p. 2861-6 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Type 1 diabetes - the copenhagen model

    Mandrup-Poulsen, Thomas, Binder, C., Deckert, T. & Nerup, J., 2007, Diabetes og Danmark. 1 ed. Gad, p. 184-195 11 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  19. Published

    Ætiologi og patogenese, Type 1

    Bergholdt, R., Larsen, C. M., Pociot, Flemming, Mandrup-Poulsen, Thomas, Hilsted, J. C., Christensen, J. S. & Borch-Johnsen, K., 2007, Diabetes. 1 ed. København: Handelshøjskolens Forlag, Vol. 6. p. -

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  20. 2006
  21. Published

    Association of interferon-gamma and interleukin 10 genotypes and serum levels with partial clinical remission in type 1 diabetes

    Alizadeh, B. Z., Hanifi-Moghaddam, P., Eerligh, P., van der Slik, A. R., Kolb, H., Kharagjitsingh, A. V., Pereira Arias, A. M., Ronkainen, M., Knip, M., Bonfanti, R., Bonifacio, E., Prasad, D., Wilkin, T., Giphart, M. J., Koeleman, B. P. C., Nolsøe, R., Mandrup-Poulsen, Thomas, Schloot, N. C., Roep, B. O. & DIABMARKER Study Group, D. S. G., 1 Sep 2006, In: Clinical and Experimental Immunology. 145, 3, p. 480-4 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Growth arrest- and DNA-damage-inducible 45beta gene inhibits c-Jun N-terminal kinase and extracellular signal-regulated kinase and decreases IL-1beta-induced apoptosis in insulin-producing INS-1E cells

    Larsen, C. M., Døssing, M. G., Papa, S., Franzoso, G., Billestrup, Nils & Mandrup-Poulsen, Thomas, 1 May 2006, In: Diabetologia. 49, 5, p. 980-9 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Plasma cytokine levels in young and elderly twins: genes versus environment and relation to in vivo insulin action

    Grunnet, Louise Groth, Poulsen, P., Pedersen, Bente Klarlund, Mandrup-Poulsen, Thomas & Vaag, A., 1 Feb 2006, In: Diabetologia. 49, 2, p. 343-50 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Cytokine-induced proapoptotic gene expression in insulin-producing cells is related to rapid, sustained, and nonoscillatory nuclear factor-kappaB activation.

    Ortis, F., Cardozo, A. K., Crispim, D., Störling, J., Mandrup-Poulsen, Thomas & Eizirik, D. L., 2006, In: Molecular Endocrinology. 20, 8, p. 1867-79 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    IL-1β-induced pro-apoptotic signaling is facilitated by NCAM/FGF receptor signaling and inhibited by the C3d ligand in the INS-1E rat beta cell line

    Petersen, L. G., Størling, J., Heding, P., Li, S., Berezin, V., Saldeen, J., Billestrup, N., Bock, E. M. & Mandrup-Poulsen, Thomas, 2006, In: Diabetologia. 49, p. 1864-75

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    IL-1beta-induced pro-apoptotic signalling is facilitated by NCAM/FGF receptor signalling and inhibited by the C3d ligand in the INS-1E rat beta cell line

    Petersen, L. G., Størling, Joachim, Heding, P., Li, S., Berezin, V., Saldeen, J., Billestrup, Nils, Bock, E. & Mandrup-Poulsen, Thomas, 2006, In: Diabetologia. 49, 8, p. 1864-75 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    RX871024 reduces NO production but does not protect against pancreatic beta-cell death induced by proinflammatory cytokines.

    Zaitseva, I. I., Sharoyko, V., Størling, J., Efendic, S., Guerin, C., Mandrup-Poulsen, Thomas, Nicotera, P., Berggren, P. & Zaitsev, S. V., 2006, In: Biochemical and Biophysical Research Communications. 347, 4, p. 1121-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Suppressor of cytokine Signaling-3 inhibits interleukin-1 signaling by targeting the TRAF-6/TAK1 complex.

    Frobøse, H., Rønn, S. G., Heding, P. E., Mendoza, H., Cohen, P., Mandrup-Poulsen, Thomas & Billestrup, N., 2006, In: Molecular Endocrinology. 20, 7, p. 1587-96 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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