Thomas Mandrup-Poulsen

Thomas Mandrup-Poulsen

Professor

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    1. Published

      Small-molecule inhibition of inflammatory β-cell death

      Lundh, M., Scully, S. S., Mandrup-Poulsen, Thomas & Wagner, B. K., Sep 2013, In: Diabetes, Obesity and Metabolism Online. 15 , 3, p. 176-84 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      Histone deacetylase 3 inhibition improves glycaemia and insulin secretion in obese diabetic rats

      Lundh, M., Galbo, T., Poulsen, Steen Seier & Mandrup-Poulsen, Thomas, Jul 2015, In: Diabetes, Obesity and Metabolism. 17, 7, p. 703-7 5 p.

      Research output: Contribution to journal › Letter › Research › peer-review

    3. Published

      The immunoproteasome is induced by cytokines and regulates apoptosis in human islets

      Lundh, M., Bugliani, M., Dahlby, T., Chou, D. H., Wagner , B., Ghiasi, S. M., De Tata, V., Chen, Z., Lund, Marianne N., Davies, Michael J., Marchetti, P. & Mandrup-Poulsen, Thomas, 2017, In: Journal of Endocrinology. 233, 3, p. 369-379 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Glucose- and interleukin-1beta-induced beta-cell apoptosis requires Ca2+ influx and extracellular signal-regulated kinase (ERK) 1/2 activation and is prevented by a sulfonylurea receptor 1/inwardly rectifying K+ channel 6.2 (SUR/Kir6.2) selective potassium channel opener in human islets.

      Maedler, K., Størling, J., Sturis, J., Zuellig, R. A., Spinas, G. A., Arkhammar, P. O. G., Mandrup-Poulsen, Thomas & Donath, M. Y., 2004, In: Diabetes. 53, 7, p. 1706-13 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      (19)F-heptuloses as tools for the non-invasive imaging of GLUT2-expressing cells

      Malaisse, W. J., Zhang, Y., Louchami, K., Sharma, S., Dresselaers, T., Himmelreich, U., Novotny, G. W., Mandrup-Poulsen, Thomas, Waschke, D., Leshch, Y., Thimm, J., Thiem, J. & Sener, A., 2012, In: Archives of Biochemistry and Biophysics. 517, 2, p. 138-43 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Pancreatic beta-cells respond to fuel pressure with an early metabolic switch

      Malinowski, R. M., Ghiasi, S. M., Mandrup-Poulsen, Thomas, Meier, S., Lerche, M. H., Ardenkjaer-Larsen, J. H. & Jensen, P. R., 2020, In: Scientific Reports. 10, 1, 11 p., 15413.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Mechanisms of pancreatic islet cell destruction. Dose-dependent cytotoxic effect of soluble blood mononuclear cell mediators on isolated islets of Langerhans

      Mandrup-Poulsen, Thomas, Bendtzen, K., Nerup, J., Egeberg, J. & Nielsen, Jens Høiriis, May 1986, In: Allergy. 41, 4, p. 250-9 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Ultrastructural studies of time-course and cellular specificity of interleukin-1 mediated islet cytotoxicity

      Mandrup-Poulsen, Thomas, Egeberg, J., Nerup, J., Bendtzen, K., Dinarello, C. A. & Nielsen, Jens Høiriis, Apr 1987, In: Acta pathologica, microbiologica, et immunologica Scandinavica. Section C, Immunology. 95, 2, p. 55-63 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Direct effects of cyclosporin A on human pancreatic beta-cells

      Mandrup-Poulsen, Thomas, Nerup, J. & Nielsen, Jens Høiriis, Sep 1986, In: Diabetes. 35, 9, p. 1049-52 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Islet cytotoxicity of interleukin 1. Influence of culture conditions and islet donor characteristics

      Mandrup-Poulsen, Thomas, Spinas, G. A., Prowse, S. J., Hansen, B. S., Jørgensen, D. W., Bendtzen, K., Nerup, J. & Nielsen, Jens Høiriis, May 1987, In: Diabetes. 36, 5, p. 641-7 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Cytokines cause functional and structural damage to isolated islets of Langerhans

      Mandrup-Poulsen, Thomas, Bendtzen, K., Bendixen, G., Nerup, J. & Nielsen, Jens Høiriis, Aug 1985, In: Allergy. 40, 6, p. 424-9 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Affinity-purified human interleukin I is cytotoxic to isolated islets of Langerhans

      Mandrup-Poulsen, Thomas, Bendtzen, K., Nerup, J., Dinarello, C. A., Svenson, M. & Nielsen, Jens Høiriis, Jan 1986, In: Diabetologia. 29, 1, p. 63-7 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Granzyme A in the Pathogenesis of Type 1 Diabetes: The Yes and the No

      Mandrup-Poulsen, Thomas, Dec 2017, In: Diabetes. 66, 12, p. 2937-2939 3 p.

      Research output: Contribution to journal › Letter › Research › peer-review

    14. Published

      Immunometabolism in 2017: Metabolism and the inflammasome in health and ageing

      Mandrup-Poulsen, Thomas, Feb 2018, In: Nature Reviews Endocrinology. 14, 2, p. 72-74 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Glutaminsyre-decarboxylase-antistoffer og diabetes.

      Mandrup-Poulsen, Thomas, 2007, In: Ugeskrift for læger. 169, 4, p. 300-4 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Interleukin-1 antagonism: a sturdy companion for immune tolerance induction in type 1 diabetes?

      Mandrup-Poulsen, Thomas, Jun 2014, In: Diabetes. 63, 6, p. 1833-5 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      IAPP boosts islet macrophage IL-1 in type 2 diabetes

      Mandrup-Poulsen, Thomas, 1 Oct 2010, In: Nature Immunology. 11, 10, p. 881-3 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Gluten under graviditeten og risiko for type 1 diabetes hos barnet: [Medicinsk nyhed]

      Mandrup-Poulsen, Thomas, 2019, In: Ugeskrift for Laeger. 22

      Research output: Contribution to journal › Comment/debate › Communication

    19. Published

      Type 2 diabetes mellitus: a metabolic autoinflammatory disease

      Mandrup-Poulsen, Thomas, Jul 2013, In: Dermatologic Clinics. 31, 3, p. 495-506 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      DIAMAP team group. Europe draws up a map to a better future: Diabetes Breakthrough

      Mandrup-Poulsen, Thomas, 2009

      Research output: Other contribution › Communication

    21. Published

      DIAMAP team group. Invitation to diabetes researchers and funding agencies to participate in an innovative European project.

      Mandrup-Poulsen, Thomas, 2009

      Research output: Other contribution › Communication

    22. Published

      Blockade of Interleukin 1 in Type 1 diabetes mellitus

      Mandrup-Poulsen, Thomas, Pickersgill, L. M. S. & Donath, M. Y., 2010, In: Nature Reviews Endocrinology. 6, p. 158-166 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Interleukin-1 antagonists and other cytokine blockade strategies for type 1 diabetes

      Mandrup-Poulsen, Thomas, 2012, In: The review of diabetic studies : RDS. 9, 4, p. 338-47 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Transplantation mellem enaeggede tvillinger

      Mandrup-Poulsen, Thomas, 26 Jan 2004, In: Ugeskrift for Laeger. 166, 5, p. 398-9; author reply 399

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Perspective: Testing failures

      Mandrup-Poulsen, Thomas, 2012, In: Nature Study. 485, 7398, p. S17

      Research output: Contribution to journal › Journal article › Commissioned

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