Thomas Mandrup-Poulsen

Thomas Mandrup-Poulsen

Professor


  1. 2012
  2. Published

    Divalent metal transporter 1 regulates iron-mediated ROS and pancreatic ß cell fate in response to cytokines

    Hansen, J. B., Tonnesen, M. F., Madsen, A. N., Hagedorn, P., Friberg, J., Grunnet, L. G., Heller, R. S., Nielsen, A. Ø., Størling, J., Baeyens, L., Anker-Kitai, L., Qvortrup, K., Bouwens, L., Efrat, S., Aalund, M., Andrews, N. C., Billestrup, N., Karlsen, A. E., Holst, B., Pociot, F. & 1 others, Mandrup-Poulsen, Thomas, 2012, In: Cell Metabolism. 16, 4, p. 449-61 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Effects of Gevokizumab on Glycemia and Inflammatory Markers in Type 2 Diabetes

    Cavelti-Weder, C., Babians-Brunner, A., Keller, C., Stahel, M. A., Kurz-Levin, M., Zayed, H., Solinger, A. M., Mandrup-Poulsen, Thomas, Dinarello, C. A. & Donath, M. Y., 2012, In: Diabetes Care.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Histone deacetylases 1 and 3 but not 2 mediate cytokine-induced beta cell apoptosis in INS-1 cells and dispersed primary islets from rats and are differentially regulated in the islets of type 1 diabetic children

    Lundh, M., Christensen, D. P., Damgaard Nielsen, M., Richardson, S. J., Dahllöf, M. S., Skovgaard, T., Berthelsen, J., Dinarello, C. A., Stevenazzi, A., Mascagni, P., Grunnet, Louise Groth, Morgan, N. G. & Mandrup-Poulsen, Thomas, 2012, In: Diabetologia. 55, 9, p. 2421-31

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Interleukin-1 antagonists and other cytokine blockade strategies for type 1 diabetes

    Mandrup-Poulsen, Thomas, 2012, In: The review of diabetic studies : RDS. 9, 4, p. 338-47 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Perspective: Testing failures

    Mandrup-Poulsen, Thomas, 2012, In: Nature Study. 485, 7398, p. S17

    Research output: Contribution to journalJournal articleCommissioned

  7. Published
  8. Published

    Synergistic reversal of type 1 diabetes in NOD mice with anti-CD3 and interleukin-1 blockade: evidence of improved immune regulation

    Ablamunits, V., Henegariu, O., Hansen, J. B., Opare-Addo, L., Preston-Hurlburt, P., Santamaria, P., Mandrup-Poulsen, Thomas & Herold, K. C., 2012, In: Diabetes. 61, 1, p. 145-54 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Transcriptional and translational regulation of cytokine signaling in inflammatory ß-cell dysfunction and apoptosis

    Novotny, G. W., Lundh, M., Backe, M. B., Christensen, D. P., Hansen, J. B., Dahllöf, M. S., Pallesen, E. & Mandrup-Poulsen, Thomas, 2012, In: Archives of Biochemistry and Biophysics. 528, 2, p. 171-84

    Research output: Contribution to journalReviewResearchpeer-review

  10. 2011
  11. Published

    Apolipoprotein CIII reduces proinflammatory cytokine-induced apoptosis in rat pancreatic islets via the Akt prosurvival pathway.

    Størling, Joachim, Juntti-Berggren, L., Olivecrona, G., Prause, Michala Cecilie Burstein, Berggren, P. & Mandrup-Poulsen, Thomas, Aug 2011, In: Endocrinology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    16 SKELETAL-MUSCLE LIPOPROTEIN EXPRESSION IS REGULATED BY TRAINING AND TYPE 2 DIABETES IN HUMANS AND IMPROVES INSULIN SENSITIVITY IN OBESE MICE

    Bartels, E. M., Mandrup-Poulsen, Thomas & Nielsen, L. B., Jun 2011, In: Atherosclerosis. Supplement. 12, 1, p. 4 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  13. Published

    The oral histone deacetylase inhibitor ITF2357 reduces cytokines and protects islet ß cells in vivo and in vitro

    Lewis, E. C., Blaabjerg, L., Størling, Joachim, Ronn, S. G., Mascagni, P., Dinarello, C. A. & Mandrup-Poulsen, Thomas, May 2011, In: Molecular Medicine. 17, 5-6, p. 369-377 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    The Trial to Reduce IDDM in the Genetically at Risk (TRIGR) study: recruitment, intervention and follow-up

    Akerblom, H. K., Krischer, J., Virtanen, V. S., Berseth, C., Becker, D., Dupré, J., Ilonen, J., Trucco, M., Savilahti, E., Koski, K., Pajakkala, E., Fransiscus, M., Lough, G., Bradley, B., Koski, M., Knip, M., TRIGR Study Group, T. S. G. & Mandrup-Poulsen, Thomas, 1 Mar 2011, In: Diabetologica. 54, 3, p. 627-633 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Direct demonstration of NCAM cis-dimerization and inhibitory effect of palmitoylation using the BRET2 technique

    Kulahin, N., Grunnet, L. G., Lundh, M., Christensen, D. P., Jorgensen, R., Heding, A., Billestrup, Nils, Berezin, V., Bock, E. & Mandrup-Poulsen, Thomas, 3 Jan 2011, In: FEBS Letters. 585, 1, p. 58-64 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Apolipoprotein CIII Reduces Proinflammatory Cytokine-Induced Apoptosis in Rat Pancreatic Islets via the Akt Prosurvival Pathway

    Størling, Joachim, Juntti-Berggren, L., Olivecrona, G., Prause, M. C., Berggren, P. & Mandrup-Poulsen, Thomas, 2011, In: Endocrinology. 152, 8, p. 3040-8 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Cytokines and type 1 diabetes: a numbers game

    Grunnet, L. G. & Mandrup-Poulsen, Thomas, 2011, In: Diabetes. 60, 3, p. 697-9 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Early feeding and risk of type 1 diabetes: experiences from the Trial to Reduce Insulin-dependent diabetes mellitus in the Genetically at Risk (TRIGR)

    Knip, M., Virtanen, S. M., Becker, D., Dupré, J., Krischer, J. P., Åkerblom, H. K., TRIGR Study Group, T. S. G. & Mandrup-Poulsen, Thomas, 2011, In: American Journal of Clinical Nutrition. 94, 6 Suppl, p. 1814S-1820S 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Elevated transferrin saturation and risk of diabetes: Three population-based studies

    Ellervik, Christina, Mandrup-Poulsen, Thomas, Andersen, H. U., Tybjærg-Hansen, Anne, Frandsen, M., Birgens, H. & Nordestgaard, Børge, 2011, In: Diabetes Care. 34, 10, p. 2256-8 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Endothelial Progenitor Cells in Long-Standing Asymptomatic Type 1 Diabetic Patients with or without Diabetic Nephropathy

    Reinhard, H., Jacobsen, P. K., Lajer, M., Tarnow, L., Astrup, A. S., Kim, W. Y., Pedersen, N., Billestrup, Nils, Mandrup-Poulsen, Thomas, Parving, H. & Rossing, Peter, 2011, In: Nephron Clinical Practice. 118, 3, p. c309-c314 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Histone deacetylase (HDAC) inhibition as a novel treatment for diabetes mellitus

    Christensen, D. P., Dahllöf, M. S., Lundh, M., Rasmussen, D. N., Nielsen, M. D., Billestrup, Nils, Grunnet, L. G. & Mandrup-Poulsen, Thomas, 2011, In: Molecular Medicine. 17, 5-6, p. 378-90 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. 2010
  23. Published

    Lysine deacetylases are produced in pancreatic beta cells and are differentially regulated by proinflammatory cytokines

    Lundh, M., Christensen, D. P., Rasmussen, D. N., Mascagni, P., Dinarello, C. A., Billestrup, Nils, Grunnet, L. G. & Mandrup-Poulsen, Thomas, 1 Dec 2010, In: Diabetologia. 53, 12, p. 2569-78 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    IL-1 family nomenclature

    Dinarello, C., Arend, W., Sims, J., Smith, D., Blumberg, H., O'Neill, L., Goldbach-Mansky, R., Pizarro, T., Hoffman, H., Bufler, P., Nold, M., Ghezzi, P., Mantovani, A., Garlanda, C., Boraschi, D., Rubartelli, A., Netea, M., van der Meer, J., Joosten, L., Mandrup-Poulsen, T. & 14 others, Donath, M., Lewis, E., Pfeilschifter, J., Martin, M., Kracht, M., Muehl, H., Novick, D., Lukic, M., Conti, B., Solinger, A., Kelk, P., Peyman, K., van de Veerdonk, F. & Gabel, C., 1 Nov 2010, In: Nature Immunology. 11, 11, p. 973 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    IAPP boosts islet macrophage IL-1 in type 2 diabetes

    Mandrup-Poulsen, Thomas, 1 Oct 2010, In: Nature Immunology. 11, 10, p. 881-3 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Multifactorial treatment increases endothelial progenitor cells in patients with type 2 diabetes

    Reinhard, H., Jacobsen, P. K., Lajer, M., Pedersen, N., Billestrup, Nils, Mandrup-Poulsen, Thomas, Parving, H. & Rossing, Peter, 1 Oct 2010, In: Diabetologica. 53, 10, p. 2129-33 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Role of IL-1beta in type 2 diabetes

    Dinarello, C. A., Donath, M. Y. & Mandrup-Poulsen, Thomas, 1 Aug 2010, In: Current Opinion in Endocrinology, Diabetes and Obesity. 17, 4, p. 314-21 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Blockade of Interleukin 1 in Type 1 diabetes mellitus

    Mandrup-Poulsen, Thomas, Pickersgill, L. M. S. & Donath, M. Y., 2010, In: Nature Reviews Endocrinology. 6, p. 158-166 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 923693