Thomas Mandrup-Poulsen

Thomas Mandrup-Poulsen

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    1. Published

      Synergistic reversal of type 1 diabetes in NOD mice with anti-CD3 and interleukin-1 blockade: evidence of improved immune regulation

      Ablamunits, V., Henegariu, O., Hansen, J. B., Opare-Addo, L., Preston-Hurlburt, P., Santamaria, P., Mandrup-Poulsen, Thomas & Herold, K. C., 2012, In: Diabetes. 61, 1, p. 145-54 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      TRAF2 mediates JNK and STAT3 activation in response to IL-1β and IFNγ and facilitates apoptotic death of insulin-producing β-cells

      Prause, Michala Cecilie Burstein, Berchtold, L. A., Urizar, A. I., Trauelsen, Mette, Billestrup, Nils, Mandrup-Poulsen, Thomas & Størling, Joachim, 15 Jan 2016, In: Molecular and Cellular Endocrinology. 420, p. 24-36 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Targeting innate immune mediators in type 1 and type 2 diabetes

      Donath, M. Y., Dinarello, C. A. & Mandrup-Poulsen, Thomas, 2019, In: Nature Reviews. Immunology. 19, 12, p. 734-746

      Research output: Contribution to journal › Review › Research › peer-review

    4. Published

      The Connexin 43 Regulator Rotigaptide Reduces Cytokine-Induced Cell Death in Human Islets

      Ghiasi, S. M., Hansen, J. B., Christensen, D. P., Tyrberg, B. & Mandrup-Poulsen, Thomas, 2020, In: International Journal of Molecular Sciences (Online). 21, 12, 15 p., 4311.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      The Faroese, a genetic isolate with a strong founder effect, allows the identification of Type 1 diabetes susceptibility regions

      Nolsoe, R., Roin, J., Deckert, M., Bergholdt, R., Kelly, J., Brorsson, C., Harley, J., Olsen, S., Pociot, Flemming & Mandrup-Poulsen, Thomas, 2008, In: Clinical Immunology. 127, Suppl. S, p. S105-S105

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      The Fas pathway is involved in pancreatic beta cell secretory function.

      Schumann, D. M., Maedler, K., Franklin, I., Konrad, D., Størling, J., Böni-Schnetzler, M., Gjinovci, A., Kurrer, M. O., Gauthier, B. R., Bosco, D., Andres, A., Berney, T., Greter, M., Becher, B., Chervonsky, A. V., Halban, P. A., Mandrup-Poulsen, Thomas, Wollheim, C. B. & Donath, M. Y., 2007, In: Proceedings of the National Academy of Science of the United States of America. 104, 8, p. 2861-6 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      The Lysine Demethylase KDM5B Regulates Islet Function and Glucose Homeostasis

      Backe, M. B., Jin, C., Andreone, L., Sankar, A., Agger, K., Helin, K., Madsen, A. N., Poulsen, Steen Seier, Bysani, M., Bacos, K., Ling, C., Javier Perone, M., Holst, Birgitte & Mandrup-Poulsen, Thomas, 2019, In: Journal of Diabetes Research. 2019, 15 p., 5451038.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      The No-Go and Nonsense-Mediated RNA Decay Pathways Are Regulated by Inflammatory Cytokines in Insulin-Producing Cells and Human Islets and Determine β-Cell Insulin Biosynthesis and Survival

      Ghiasi, S. M., Krogh, Nicolai, Tyrberg, B. & Mandrup-Poulsen, Thomas, 2018, In: Diabetes. 67, 10, p. 2019-2037 19 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      The Trial to Reduce IDDM in the Genetically at Risk (TRIGR) study: recruitment, intervention and follow-up

      Akerblom, H. K., Krischer, J., Virtanen, V. S., Berseth, C., Becker, D., Dupré, J., Ilonen, J., Trucco, M., Savilahti, E., Koski, K., Pajakkala, E., Fransiscus, M., Lough, G., Bradley, B., Koski, M., Knip, M., TRIGR Study Group, T. S. G. & Mandrup-Poulsen, Thomas, 1 Mar 2011, In: Diabetologica. 54, 3, p. 627-633 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      The anti-interleukin-1 in type 1 diabetes action trial - Background and rationale

      Pickersgill, L. M. S. & Mandrup-Poulsen, Thomas, 2009, In: Diabetes - Metabolism: Research and Reviews (Print Edition). 25, 4, p. 321-324 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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