Thomas Mandrup-Poulsen

Thomas Mandrup-Poulsen

Professor

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    151 - 175 out of 206Page size: 25
    1. 2016
    2. Published

      TRAF2 mediates JNK and STAT3 activation in response to IL-1β and IFNγ and facilitates apoptotic death of insulin-producing β-cells

      Prause, Michala Cecilie Burstein, Berchtold, L. A., Urizar, A. I., Trauelsen, Mette, Billestrup, Nils, Mandrup-Poulsen, Thomas & Størling, Joachim, 15 Jan 2016, In: Molecular and Cellular Endocrinology. 420, p. 24-36 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      An Isochemogenic Set of Inhibitors To Define the Therapeutic Potential of Histone Deacetylases in β-Cell Protection

      Wagner, F. F., Lundh, M., Kaya, T., McCarren, P., Zhang, Y-L., Chattopadhyay, S., Gale, J. P., Galbo, T., Fisher, S. L., Meier, B. C., Vetere, A., Richardson, S., Morgan, N. G., Christensen, D. P., Gilbert, T. J., Hooker, J. M., Leroy, M., Walpita, D., Mandrup-Poulsen, T., Wagner, B. K. & 1 others, Holson, E. B., 19 Feb 2016, In: ACS chemical biology. 11, 2, p. 363-374 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Interleukin-1 antagonism moderates the inflammatory state associated with Type 1 diabetes during clinical trials conducted at disease onset

      Cabrera, S. M., Wang, X., Chen, Y., Jia, S., Kaldunski, M. L., Greenbaum, C. J., Mandrup-Poulsen, Thomas & Hessner, M. J., Apr 2016, In: European Journal of Immunology. 46, 4, p. 1030-1046 17 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      MicroRNAs as regulators of beta-cell function and dysfunction

      Osmai, M., Osmai, Y., Bang-Berthelsen, C. H., Pallesen, E. M. H., Vestergaard, A. L., Novotny, G. W., Pociot, Flemming & Mandrup-Poulsen, Thomas, May 2016, In: Diabetes - Metabolism: Research and Reviews (Print Edition). 32, 4, p. 334–349 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      A Placebo-Controlled Study on the Effects of the Glucagon-Like Peptide-1 Mimetic, Exenatide, on Insulin Secretion, Body Composition and Adipokines in Obese, Client-Owned Cats

      Hoelmkjaer, K. M., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Cronin, A. M., Nielsen, Dorte Hald, Mandrup-Poulsen, Thomas & Bjørnvad, Charlotte Reinhard, 2 May 2016, In: P L o S One. 11, 5, 18 p., e0154727.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Cytokines and Pancreatic β-Cell Apoptosis

      Berchtold, L. A., Prause, Michala Cecilie Burstein, Størling, Joachim & Mandrup-Poulsen, Thomas, 28 Jun 2016, Advances in Clinical Chemistry. Academic Press, Vol. 75. p. 99-158 60 p. (Advances in Clinical Chemistry, Vol. 75).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    8. Published

      Iron Regulation of Pancreatic Beta-Cell Functions and Oxidative Stress

      Backe, M. B., Moen, I. W., Ellervik, Christina, Hansen, J. B. & Mandrup-Poulsen, Thomas, 17 Jul 2016, In: Annual Review of Nutrition. 36, p. 241-273 33 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. 2017
    10. Published

      The immunoproteasome is induced by cytokines and regulates apoptosis in human islets

      Lundh, M., Bugliani, M., Dahlby, T., Chou, D. H., Wagner , B., Ghiasi, S. M., De Tata, V., Chen, Z., Lund, Marianne N., Davies, Michael J., Marchetti, P. & Mandrup-Poulsen, Thomas, 2017, In: Journal of Endocrinology. 233, 3, p. 369-379 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      A guiding map for inflammation

      Netea, M. G., Balkwill, F., Chonchol, M., Cominelli, F., Donath, M. Y., Giamarellos-Bourboulis, E. J., Golenbock, D., Gresnigt, M. S., Heneka, M. T., Hoffman, H. M., Hotchkiss, R., Joosten, L. A. B., Kastner, D. L., Korte, M., Latz, E., Libby, P., Mandrup-Poulsen, T., Mantovani, A., Mills, K. H. G., Nowak, K. L. & 12 others, O'Neill, L. A., Pickkers, P., van der Poll, T., Ridker, P. M., Schalkwijk, J., Schwartz, D. A., Siegmund, B., Steer, C. J., Tilg, H., van der Meer, J. W. M., van de Veerdonk, F. L. & Dinarello, C. A., 19 Jul 2017, In: Nature Immunology. 18, 8, p. 826-831 6 p.

      Research output: Contribution to journal › Comment/debate › Research › peer-review

    12. Published

      Cardiovascular and All-Cause Mortality Risk Associated With Urinary Excretion of 8-oxoGuo, a Biomarker for RNA Oxidation, in Patients With Type 2 Diabetes: A Prospective Cohort Study

      Kjær, L. K., Cejvanovic, V., Henriksen, T., Petersen, K. M., Hansen, Torben, Pedersen, Oluf Borbye, Christensen, C. K., Torp-Pedersen, C., Gerds, Thomas Alexander, Brandslund, I., Mandrup-Poulsen, Thomas & Poulsen, Henrik Enghusen, Dec 2017, In: Diabetes Care. 40, 12, p. 1771-1778 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Granzyme A in the Pathogenesis of Type 1 Diabetes: The Yes and the No

      Mandrup-Poulsen, Thomas, Dec 2017, In: Diabetes. 66, 12, p. 2937-2939 3 p.

      Research output: Contribution to journal › Letter › Research › peer-review

    14. 2018
    15. Published

      Acute administration of interleukin-6 does not increase secretion of glucagon-like peptide-1 in mice

      Christiansen, Charlotte Bayer, Jepsen, Sara Lind, Svendsen, B., Balk-Møller, E., Dahlby, T., Kuhre, Rune Ehrenreich, Hartmann, Bolette, Mandrup-Poulsen, Thomas, Deacon, Carolyn F., Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2018, In: Physiological Reports. 6, 13, p. 1-8 e13788.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Effect of Hydrolyzed Infant Formula vs Conventional Formula on Risk of Type 1 Diabetes: The TRIGR Randomized Clinical Trial

      TRIGR Study Group, T. S. G., 2018, In: J A M A: The Journal of the American Medical Association. 319, 1, p. 38-48

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Glucolipotoxic conditions induce beta-cell iron import, cytosolic ROS formation and apoptosis

      Hansen, J. B., Dos Santos, L. R. B., Liu, Y., Prentice, K. J., Teudt, F., Tonnesen, M., Jonas, J., Wheeler, M. B. & Mandrup-Poulsen, Thomas, 2018, In: Journal of Molecular Endocrinology. 61, 2, p. 69-77

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Increased Plasma Ferritin Concentration and Low-Grade Inflammation-A Mendelian Randomization Study

      Moen, I. W., Bergholdt, H. K. M., Mandrup-Poulsen, Thomas, Nordestgaard, Børge & Ellervik, Christina, 2018, In: Clinical Chemistry. 64, 2, p. 374-385 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Interleukin-37 treatment of mice with metabolic syndrome improves insulin sensitivity and reduces pro-inflammatory cytokine production in adipose tissue

      Ballak, D. B., Li, S., Cavalli, G., Stahl, J. L., Tengesdal, I. W., van Diepen, J. A., Kluck, V., Swartzwelter, B., Azam, T., Tack, C. J., Stienstra, R., Mandrup-Poulsen, Thomas, Seals, D. R. & Dinarello, C. A., 2018, In: Journal of Biological Chemistry. 293, 37, p. 14224-14236

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Iron Status and Gestational Diabetes: A Meta-Analysis

      Kataria, Y., Wu, Y., Horskjaer, P. D. H., Mandrup-Poulsen, Thomas & Ellervik, Christina, 2018, In: Nutrients. 10, 5, 15 p., 621 .

      Research output: Contribution to journal › Review › Research › peer-review

    21. Published

      Regulation of the beta-cell inflammasome and contribution to stress-induced cellular dysfunction and apoptosis

      Ghiasi, S. M., Dahllöf, M. S., Osmai, Y., Osmai, M., Jakobsen, K. K., Aivazidis, A., Tyrberg, B., Perruzza, L., Prause, Michala Cecilie Burstein, Christensen, D. P., Fog-Tonnesen, M., Lundh, M., Grassi, F., Chatenoud, L. & Mandrup-Poulsen, Thomas, 2018, In: Molecular and Cellular Endocrinology. 478, p. 106-114

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      The No-Go and Nonsense-Mediated RNA Decay Pathways Are Regulated by Inflammatory Cytokines in Insulin-Producing Cells and Human Islets and Determine β-Cell Insulin Biosynthesis and Survival

      Ghiasi, S. M., Krogh, Nicolai, Tyrberg, B. & Mandrup-Poulsen, Thomas, 2018, In: Diabetes. 67, 10, p. 2019-2037 19 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Lysine demethylase inhibition protects pancreatic β cells from apoptosis and improves β-cell function

      Backe, M. B., Andersson, J. L., Bacos, K., Christensen, D. P., Hansen, J. B., Dorosz, J. J., Gajhede, Michael, Dahlby, T., Bysani, M., Kristensen, L. H., Ling, C., Olsen, L. & Mandrup-Poulsen, Thomas, 15 Jan 2018, In: Molecular and Cellular Endocrinology. 460, p. 47-56 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Immunometabolism in 2017: Metabolism and the inflammasome in health and ageing

      Mandrup-Poulsen, Thomas, Feb 2018, In: Nature Reviews Endocrinology. 14, 2, p. 72-74 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Oral histone deacetylase inhibitor synergises with T cell targeted immunotherapy to preserve beta cell metabolic function and induce stable remission of new-onset autoimmune diabetes in NOD mice

      Besançon, A., Goncalves, T., Valette, F., Dahllöf, M. S., Mandrup-Poulsen, Thomas, Chatenoud, L. & You, S., 1 Feb 2018, In: Diabetologia. 61, 2, p. 389-398 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      MicroRNAs and histone deacetylase inhibition-mediated protection against inflammatory β-cell damage

      Vestergaard, A. L., Bang-Berthelsen, C. H., Floyel, T., Stahl, J. L., Christen, L., Sotudeh, F. T., Horskjaer, P. D. H., Frederiksen, K. S., Kofod, F. G., Bruun, C., Berchtold, L. A., Storling, J., Regazzi, R., Kaur, S., Pociot, Flemming & Mandrup-Poulsen, Thomas, 27 Sep 2018, In: PLOS ONE. 13, 9, p. 1-22 22 p., e0203713 .

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. 2019
    28. Published

      Gluten under graviditeten og risiko for type 1 diabetes hos barnet: [Medicinsk nyhed]

      Mandrup-Poulsen, Thomas, 2019, In: Ugeskrift for Laeger. 22

      Research output: Contribution to journal › Comment/debate › Communication

    29. Published

      Inflammatory and metabolic stress perturbs the beta cell circadian clock: [Meeting Abstract]

      Andersen, Phillip Alexander Keller, Rose, P. H., Koomen, M., Petrenko, V., Dahlby, T., Ghiasi, S. M., Dibner, C. & Mandrup-Poulsen, Thomas, 2019, In: Diabetologia. 62, Supl. 1/SI, p. S120-S120 237.

      Research output: Contribution to journal › Conference abstract in journal › Research

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