Thomas Jespersen

Thomas Jespersen

Professor

Member of:


    1. 2018
    2. Published

      Effect of induced chronic atrial fibrillation on exercise performance in Standardbred trotters

      Buhl, Rikke, Carstensen, Helena, Hesselkilde, E. Z., Klein, B. Z., Hougaard, K. M., Ravn, K. B., Loft-Andersen, A. V., Fenner, Merle Friederike, Pipper, C. & Jespersen, Thomas, 2018, In: Journal of Veterinary Internal Medicine. 32, 4, p. 1410-1419 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. Published

      Inhibition of Small Conductance Calcium-Activated Potassium (SK) Channels Prevents Arrhythmias in Rat Atria During beta-Adrenergic and Muscarinic Receptor Activation

      Skibsbye, L., Bengaard, A. K., Uldum-Nielsen, A. M., Boddum, K., Christ, T. & Jespersen, Thomas, 2018, In: Frontiers in Physiology. 9

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. Published

      Next-generation sequencing of AV nodal reentrant tachycardia patients identifies broad spectrum of variants in ion channel genes

      Andreasen, Laura Korsholm, Ahlberg, G., Tang, C., Andreasen, C., Hartmann, J. P., Tfelt-Hansen, Jacob, Behr, E. R., Pehrson, S., Haunsø, Stig, LuCamp, Weeke, P. E., Jespersen, Thomas, Olesen, Morten Steen Salling & Svendsen, Jesper Hastrup, 2018, In: European Journal of Human Genetics. 26, p. 660–668

      Research output: Contribution to journalJournal articleResearchpeer-review

    5. Published

      Pharmacological rescue of mutated K(v)3.1 ion-channel linked to progressive myoclonus epilepsies

      Munch, A. S., Saljic, Arnela, Boddum, K., Grunnet, Morten, Hougaard, C. & Jespersen, Thomas, 2018, In: European Journal of Pharmacology. 833, p. 255-262

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. Published

      The sodium channel activator Lu AE98134 normalizes the altered firing properties of fast spiking interneurons in Dlx5/6+/- mice

      von Schoubye, N. L., Frederiksen, K., Kristiansen, Uffe, Petersen, A. V., Dalby, N. O., Grunnet, M., Jensen, H. S., Jespersen, Thomas, Sohal, V. S. & Perrier, Jean-Francois Marie, 2018, In: Neuroscience Letters. 662, p. 29-35 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. Published

      Time-dependent antiarrhythmic effects of flecainide on induced atrial fibrillation in horses

      Carstensen, Helena, Hesselkilde, E. Z., Fenner, Merle Friederike, Loft-Andersen, A. V., Flethøj, M., Kanters, Jørgen K., Sattler, Stefan M, Tfelt-Hansen, Jacob, Pehrson, S., Jespersen, Thomas & Buhl, Rikke, 2018, In: Journal of Veterinary Internal Medicine. 32, 5, p. 1708-1717 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. 2017
    9. Published

      Effect of flecainide on atrial fibrillatory rate in a large animal model with induced atrial fibrillation

      Hesselkilde, E. Z., Carstensen, Helena, Haugaard, M. M., Carlson, J., Pehrson, S., Jespersen, Thomas, Buhl, Rikke & Platonov, P. G., Dec 2017, In: B M C Cardiovascular Disorders. 17, 6 p., 289.

      Research output: Contribution to journalJournal articleResearchpeer-review

    10. Published

      Two missense mutations in KCNQ1 cause pituitary hormone deficiency and maternally inherited gingival fibromatosis

      Tommiska, J., Känsäkoski, J., Skibsbye, L., Vaaralahti, K., Liu, X., Lodge, E. J., Tang, C., Yuan, L., Fagerholm, R., Kanters, J. K., Lahermo, P., Kaunisto, M., Keski-Filppula, R., Vuoristo, S., Pulli, K., Ebeling, T., Valanne, L., Sankila, E-M., Kivirikko, S., Lääperi, M. & 15 others, Casoni, F., Giacobini, P., Phan-Hug, F., Buki, T., Tena-Sempere, M., Pitteloud, N., Veijola, R., Lipsanen-Nyman, M., Kaunisto, K., Mollard, P., Andoniadou, C. L., Hirsch, J. A., Varjosalo, M., Jespersen, Thomas & Raivio, T., 3 Nov 2017, In: Nature Communications. 8, 1, 11 p., 1289.

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. Published

      Rat Models of Ventricular Fibrillation Following Acute Myocardial Infarction

      Hundahl, L. A., Tfelt-Hansen, Jacob & Jespersen, Thomas, Nov 2017, In: Journal of Cardiovascular Pharmacology and Therapeutics. 22, 6, p. 514-528 15 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    12. Published

      Termination of Vernakalant-Resistant Atrial Fibrillation by Inhibition of Small-Conductance Ca2+-Activated K+ Channels in Pigs

      Diness, Jonas Goldin, Skibsbye, L., Simó-Vicens, R., Louro Larupa dos Santos, J., Lundegaard, Pia Rengtved, Citerni, C., Sauter, D. R. P., Bomholtz, Sofia Hammami, Svendsen, Jesper Hastrup, Olesen, Søren-Peter, Sørensen, U. S., Jespersen, Thomas, Grunnet, Morten & Bentzen, Bo Hjorth, 10 Oct 2017, In: Circulation: Arrhythmia and Electrophysiology. 10, 19 p., e005125.

      Research output: Contribution to journalJournal articleResearchpeer-review

    13. Published

      Pharmacological blockade of small conductance Ca-activated K channels by ICA reduces arrhythmic load in rats with acute myocardial infarction

      Hundahl, L. A., Sattler, S. M., Skibsbye, L., Diness, J. G., Tfelt-Hansen, Jacob & Jespersen, Thomas, Jun 2017, In: Pflügers Archiv - European Journal of Physiology. 469, 5-6, p. 739-750 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. Published

      A Multiple Kernel Learning Framework to Investigate the Relationship Between Ventricular Fibrillation and First Myocardial Infarction

      Marciniak, M., Arevalo, H., Tfelt-Hansen, Jacob, Ahtarovski, K. A., Jespersen, Thomas, Jabbari, R., Glinge, C., Vejlstrup, N., Engstrøm, Thomas, Maleckar, M. M. & McLeod, K., 1 Jan 2017, Functional Imaging and Modelling of the Heart: 9th International Conference, FIMH 2017, Toronto, ON, Canada, June 11-13, 2017, Proceedings. Springer, p. 161-171 11 p. (Lecture Notes in Computer Science, Vol. 10263 LNCS).

      Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

    15. Published

      From CMR Image to Patient-Specific Simulation and Population-Based Analysis: Tutorial for an Openly Available Image-Processing Pipeline

      Marciniak, M., Arevalo, H., Tfelt-Hansen, Jacob, Jespersen, Thomas, Jabbari, R., Glinge, C., Ahtarovski, K. A., Vejlstrup, N., Engstrøm, Thomas, Maleckar, M. M. & McLeod, K., 1 Jan 2017, Statistical Atlases and Computational Models of the Heart: Imaging and Modelling Challenges - 7th International Workshop, STACOM 2016 Held in Conjunction with MICCAI 2016, Revised Selected Papers. Springer, p. 106-117 12 p. (Lecture Notes in Computer Science, Vol. 10124 LNCS).

      Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

    16. Published

      Electrophysiologic effects of the IK1 inhibitor PA-6 are modulated by extracellular potassium in isolated guinea pig hearts

      Hoeker, G. S., Skarsfeldt, M. A., Jespersen, Thomas & Poelzing, S., Jan 2017, In: Physiological Reports. 5, 1, 10 p., e13120.

      Research output: Contribution to journalJournal articleResearchpeer-review

    17. Published

      Kv3.1/Kv3.2 channel positive modulators enable faster activating kinetics and increase firing frequency in fast-spiking GABAergic interneurons

      Boddum, K., Hougaard, C., Xiao-Ying Lin, J., von Schoubye, N. L., Jensen, H. S., Grunnet, M. & Jespersen, Thomas, 2017, In: Neuropharmacology. 118, p. 102-112 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    18. Published

      Kredsløbet ændres ved overvægt i barndommen

      Lund, Morten Asp Vonsild, Holm, Jens-Christian, Jespersen, Thomas & von Holstein-Rathlou, Niels-Henrik, 2017, In: Ugeskrift for Laeger. 2018, 6, p. 2-6 5 p., V03170265.

      Research output: Contribution to journalJournal articleResearchpeer-review

    19. Published
    20. Published

      Stability of Circulating Blood-Based MicroRNAs - Pre-Analytic Methodological Considerations

      Glinge, C., Clauss, S., Boddum, K., Jabbari, R., Jabbari, J., Risgaard, B., Tomsits, P., Hildebrand, B., Kääb, S., Wakili, R., Jespersen, Thomas & Tfelt-Hansen, Jacob, 2017, In: PLOS ONE. 12, 2, 16 p., e0167969.

      Research output: Contribution to journalJournal articleResearchpeer-review

    21. 2016
    22. Published

      Refractoriness in human atria: Time and voltage dependence of sodium channel availability

      Skibsbye, L., Jespersen, Thomas, Christ, T., Maleckar, M. M., van den Brink, J., Tavi, P. & Koivumäki, J. T., Dec 2016, In: Journal of Molecular and Cellular Cardiology. 101, p. 26-34 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    23. Published

      Antiarrhythmic effect of the Ca(2+)-activated K(+) (SK) channel inhibitor ICA combined with either amiodarone or dofetilide in an isolated heart model of atrial fibrillation

      Kirchhoff, J. E., Diness, Jonas Goldin, Abildgaard, L., Sheykhzade, Majid, Grunnet, Morten & Jespersen, Thomas, 8 Oct 2016, In: Pfluegers Archiv. 468, 11, p. 1853–1863 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    24. Published

      Pharmacological inhibition of I-K1 by PA-6 in isolated rat hearts affects ventricular repolarization and refractoriness

      Skarsfeldt, M. A., Carstensen, Helena, Skibsbye, L., Tang, C., Buhl, Rikke, Bentzen, Bo Hjorth & Jespersen, Thomas, Apr 2016, In: Physiological Reports. 4, 8, 11 p., e12734.

      Research output: Contribution to journalJournal articleResearchpeer-review

    25. Published

      Pharmacological exploration of the resting membrane potential reserve: Impact on atrial fibrillation

      van der Heyden, M. A. G. & Jespersen, Thomas, 15 Jan 2016, In: European Journal of Pharmacology. 771, p. 56-64 9 p.

      Research output: Contribution to journalReviewResearchpeer-review

    26. Published

      The arrhythmogenic calmodulin mutation D129G dysregulates cell growth, calmodulin-dependent kinase II activity, and cardiac function in zebrafish

      Berchtold, Martin Werner, Zacharias, T., Kulej, K., Wang, K., Torggler, R., Jespersen, Thomas, Chen, J. N., Larsen, M. R. & la Cour, J. M., 2016, In: Journal of Biological Chemistry. 291, 52, p. 26636-26646 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    27. 2015
    28. Published

      Biophysical characterization of inwardly rectifying potassium currents (I(K1) I(K,ACh), I(K,Ca)) using sinus rhythm or atrial fibrillation action potential waveforms

      Tang, C., Skibsbye, L., Yuan, L., Bentzen, Bo Hjorth & Jespersen, Thomas, Oct 2015, In: General Physiology and Biophysics. 34, 4, p. 383-92 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    29. Published

      Antiarrhythmic Mechanisms of SK Channel Inhibition in the Rat Atrium

      Skibsbye, L., Wang, X., Axelsen, L. N., Bomholtz, Sofia Hammami, Nielsen, Morten Schak, Grunnet, Morten, Bentzen, Bo Hjorth & Jespersen, Thomas, Aug 2015, In: Journal of Cardiovascular Pharmacology. 66, 2, p. 165-176 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    ID: 8117