Nils Billestrup
Professor
- 2014
- Published
Lysine deacetylase inhibition prevents diabetes by chromatin-independent immunoregulation and β-cell protection
Christensen, D. P., Gysemans, C., Lundh, M., Dahllöf, M. S., Noesgaard, D., Schmidt, S. F., Mandrup, S., Birkbak, N., Workman, C., Piemonti, L., Blaabjerg, L., Monzani, V., Fossati, G., Mascagni, P., Paraskevas, S., Aikin, R. A., Billestrup, N., Grunnet, L. G., Dinarello, C. A., Mathieu, C. & 1 others, , 6 Jan 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 3, p. 1055-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
JNK1 protects against glucolipotoxicity-mediated beta-cell apoptosis
Prause, Michala Cecilie Burstein, Christensen, D. P., Billestrup, Nils & Mandrup-Poulsen, Thomas, 2014, In: PLOS ONE. 9, 1, p. 1-11 11 p., e87067.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
Growth arrest specific protein (GAS) 6: a role in the regulation of proliferation and functional capacity of the perinatal rat beta cell
Haase, T. N., Rasmussen, M., Jaksch, C. A. M., Gaarn, L. W., Petersen, C. K., Billestrup, Nils & Nielsen, Jens Høiriis, Apr 2013, In: Diabetologia. 56, 4, p. 763-773 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
Divalent metal transporter 1 regulates iron-mediated ROS and pancreatic ß cell fate in response to cytokines
Hansen, J. B., Tonnesen, M. F., Madsen, A. N., Hagedorn, P., Friberg, J., Grunnet, L. G., Heller, R. S., Nielsen, A. Ø., Størling, J., Baeyens, L., Anker-Kitai, L., Qvortrup, K., Bouwens, L., Efrat, S., Aalund, M., Andrews, N. C., Billestrup, N., Karlsen, A. E., Holst, B., Pociot, F. & 1 others, , 2012, In: Cell Metabolism. 16, 4, p. 449-61 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
ID'ing a novel inhibitor of β-cell function, Id1
Billestrup, Nils, Oct 2011, In: Diabetes. 60, 10, p. 2455-6 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ß-cell specific overexpression of suppressor of cytokine signalling-3 does not protect against multiple low dose streptozotocin induced type 1 diabetes in mice
Börjesson, A., Rønn, S. G., Karlsen, A. E., Billestrup, Nils & Sandler, S., 30 Apr 2011, In: Immunology Letters. 136, 1, p. 74-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Direct demonstration of NCAM cis-dimerization and inhibitory effect of palmitoylation using the BRET2 technique
Kulahin, N., Grunnet, L. G., Lundh, M., Christensen, D. P., Jorgensen, R., Heding, A., Billestrup, Nils, Berezin, V., Bock, E. & Mandrup-Poulsen, Thomas, 3 Jan 2011, In: FEBS Letters. 585, 1, p. 58-64 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Endothelial Progenitor Cells in Long-Standing Asymptomatic Type 1 Diabetic Patients with or without Diabetic Nephropathy
Reinhard, H., Jacobsen, P. K., Lajer, M., Tarnow, L., Astrup, A. S., Kim, W. Y., Pedersen, N., Billestrup, Nils, Mandrup-Poulsen, Thomas, Parving, H. & Rossing, Peter, 2011, In: Nephron Clinical Practice. 118, 3, p. c309-c314 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Histone deacetylase (HDAC) inhibition as a novel treatment for diabetes mellitus
Christensen, D. P., Dahllöf, M. S., Lundh, M., Rasmussen, D. N., Nielsen, M. D., Billestrup, Nils, Grunnet, L. G. & Mandrup-Poulsen, Thomas, 2011, In: Molecular Medicine. 17, 5-6, p. 378-90 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
Lysine deacetylases are produced in pancreatic beta cells and are differentially regulated by proinflammatory cytokines
Lundh, M., Christensen, D. P., Rasmussen, D. N., Mascagni, P., Dinarello, C. A., Billestrup, Nils, Grunnet, L. G. & Mandrup-Poulsen, Thomas, 1 Dec 2010, In: Diabetologia. 53, 12, p. 2569-78 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multifactorial treatment increases endothelial progenitor cells in patients with type 2 diabetes
Reinhard, H., Jacobsen, P. K., Lajer, M., Pedersen, N., Billestrup, Nils, Mandrup-Poulsen, Thomas, Parving, H. & Rossing, Peter, 1 Oct 2010, In: Diabetologica. 53, 10, p. 2129-33 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Deficient SOCS3 and SHP-1 Expression in Psoriatic T Cells
Eriksen, K. W., Woetmann, Anders , Skov, Lone, Krejsgaard, T., Bovin, L. F., Hansen, M. L., Grønbæk, Kirsten, Billestrup, Nils, Nissen, Mogens Holst, Geisler, Carsten, Wasik, M. A. & Ødum, Niels, 2010, In: Journal of Investigative Dermatology. 130, 6, p. 1590-7 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dissociation between skeletal muscle inhibitor-{kappa}B kinase/nuclear factor-{kappa}B pathway activity and insulin sensitivity in nondiabetic twins
Friedrichsen, M., Ribel-Madsen, R., Wojtaszewski, Jørgen F P, Grunnet, Louise Groth, Richter, Erik A., Billestrup, Nils, Ploug, Thorkil, Vaag, A. & Poulsen, P., 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 1, p. 414-421 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Accepted/In press
Genetic deficiency of tissue inhibitor of metalloproteinase (TIMP) 1 does not affect apoptosis in cytokine-exposed mouse islets in vitro.
Hansen, J. B., Tonnesen, M. F., Rømer, M. U. K., Billestrup, Nils, Brunner, N. & Mandrup-Poulsen, Thomas, 2010, (Accepted/In press).Research output: Contribution to conference › Conference abstract for conference › Research
- 2009
- Published
Inhibition of nuclear factor-kappaB or Bax prevents endoplasmic reticulum stress- but not nitric oxide-mediated apoptosis in INS-1E cells
Tonnesen, M. F., Grunnet, L. G., Friberg, J., Cardozo, A. K., Billestrup, Nils, Eizirik, D. L., Størling, Joachim & Mandrup-Poulsen, Thomas, Sep 2009, In: Endocrinology. 150, 9, p. 4094-103 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
CRFR1 is expressed on pancreatic beta cells, promotes beta cell proliferation, and potentiates insulin secretion in a glucose-dependent manner
Huising, M. O., van der Meulen, T., Vaughan, J. M., Matsumoto, M., Donaldson, C. J., Park, H., Billestrup, Nils & Vale, W. W., 2009, In: Proceedings of the National Academy of Science of the United States of America. 107, 2, p. 912-7 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
IL-1 beta-induced chemokine and Fas expression are inhibited by suppressor of cytokine signalling-3 in insulin-producing cells
Jacobsen, M. L. B., Ronn, S. G., Bruun, C., Larsen, C. M., Eizirik, D. L., Mandrup-Poulsen, Thomas & Billestrup, Nils, 2009, In: Diabetologia. 52, 2, p. 281-288 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of Nuclear Factor-kappa B or Bax Prevents Endoplasmic Reticulum Stress-But Not Nitric Oxide-Mediated Apoptosis in INS-1E Cells
Tonnesen, M. F., Grunnet, L. G., Friberg, J., Cardozo, A. K., Billestrup, Nils, Eizirik, D. L., Storling, J. & Mandrup-Poulsen, Thomas, 2009, In: Endocrinology. 150, 9, p. 4094-4103 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proinflammatory cytokines activate the intrinsic apoptotic pathway in beta-cells
Grunnet, L. G., Aikin, R., Tonnesen, M. F., Paraskevas, S., Blaabjerg, L., Størling, J., Rosenberg, L., Billestrup, Nils, Maysinger, D. & Mandrup-Poulsen, Thomas, 2009, In: Diabetes. 58, 8, p. 1807-15 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Suppressor of cytokine signalling-3 inhibits Tumor necrosis factor-alpha induced apoptosis and signalling in beta cells
Bruun, C., Heding, P. E., Rønn, S. G., Frobøse, H., Rhodes, C. J., Mandrup-Poulsen, Thomas & Billestrup, Nils, 2009, In: Molecular and Cellular Endocrinology. 311, 1-2, p. 32-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The ectopic expression of Pax4 in the mouse pancreas converts progenitor cells into alpha and subsequently beta cells
Collombat, P., Xu, X., Ravassard, P., Sosa-Pineda, B., Dussaud, S., Billestrup, Nils, Madsen, O. D., Serup, P., Heimberg, H. & Mansouri, A., 2009, In: Cell. 138, 3, p. 449-62 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
- Published
Dedifferentiation for replication of human beta-cells: a division between mice and men?
Billestrup, Nils & Otonkoski, T., 2008, In: Diabetes. 57, 6, p. 1457-8 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
IL-1beta-induced chemokine and Fas expression are inhibited by suppressor of cytokine signalling-3 in insulin-producing cells
Jacobsen, M. L. B., Rønn, S. G., Bruun, C., Larsen, C. M., Eizirik, D. L., Mandrup-Poulsen, Thomas & Billestrup, Nils, 2008, In: Diabetologia. 52, 2, p. 281-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of fasting on growth hormone signaling and action in muscle and fat
Moller, L., Dalman, L., Norrelund, H., Billestrup, Nils, Frystyk, J., Moller, N. & Jorgensen, J. O. L., 2008, In: Journal of Clinical Endocrinology and Metabolism. 94, 3, p. 965-72 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proliferation of sorted human and rat beta cells
Parnaud, G., Bosco, D., Berney, T., Pattou, F., Kerr-Conte, J., Donath, M. Y., Bruun, C., Mandrup-Poulsen, Thomas, Billestrup, Nils & Halban, P. A., 2008, In: Diabetologia. 51, 1, p. 91-100 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 15311848
Most downloads
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JNK1 Deficient Insulin-Producing Cells Are Protected against Interleukin-1 beta-Induced Apoptosis Associated with Abrogated Myc Expression
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
38
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Butyrate protects pancreatic beta cells from cytokine-induced dysfunction
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
32
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Butyrate inhibits IL-1β-induced inflammatory gene expression by suppression of NF-κB activity in pancreatic beta cells
Research output: Contribution to journal › Journal article › Research › peer-review
Published