Julien Ochala

Julien Ochala

Associate Professor - Promotion Programme

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    ORCID: 0000-0002-6358-2920

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    1. Published

      Myopathy-inducing mutation H40Y in ACTA1 hampers actin filament structure and function

      Chan, C., Fan, J., Messer, A. E., Marston, S. B., Iwamoto, H. & Ochala, Julien, 1 Aug 2016, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1862, 8, p. 1453-1458 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      Myosin Heavy Chain as a Novel Key Modulator of Striated Muscle Resting State

      Lewis, Christopher T.A. & Ochala, Julien, 2023, In: Physiology. 38, 1, p. 3-9

      Research output: Contribution to journal › Review › Research › peer-review

    3. Published

      Myosin post-translational modifications and function in the presence of myopathy-linked truncating MYH2 mutations

      Sonne, A., Peverelli, L., Hernandez-Lain, A., Domínguez-González, C., Andersen, J. L., Milone, M., Beggs, A. H. & Ochala, Julien, 2023, In: American journal of physiology. Cell physiology. 324, 3, p. C769–C776 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Myostatin inhibition using mrk35 produces skeletal muscle growth and tubular aggregate formation in wild type and TgACTA1D286G nemaline myopathy mice

      Tinklenberg, J. A., Siebers, E. M., Beatka, M. J., Meng, H., Yang, L., Zhang, Z., Ross, J. A., Ochala, Julien, Morris, C., Owens, J. M., Laing, N. G., Nowak, K. J. & Lawlor, M. W., 15 Feb 2018, In: Human Molecular Genetics. 27, 4, p. 638-648 11 p., ddx431.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Nebulin nemaline myopathy recapitulated in a compound heterozygous mouse model with both a missense and a nonsense mutation in Neb

      Laitila, J. M., McNamara, E. L., Wingate, C. D., Goullee, H., Ross, J. A., Taylor, R. L., Van Der Pijl, R., Griffiths, L. M., Harries, R., Ravenscroft, G., Clayton, J. S., Sewry, C., Lawlor, M. W., Ottenheijm, C. A. C., Bakker, A. J., Ochala, Julien, Laing, N. G., Wallgren-Pettersson, C., Pelin, K. & Nowak, K. J., 17 Feb 2020, In: Acta Neuropathologica Communications. 8, 1, 18.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Nemaline Myopathy-Related Skeletal Muscle α-Actin (ACTA1) Mutation, Asp286Gly, Prevents Proper Strong Myosin Binding and Triggers Muscle Weakness

      Ochala, Julien, Ravenscroft, G., Laing, N. G. & Nowak, K. J., 20 Sep 2012, In: PLoS ONE. 7, 9, e45923.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Novel myosin-based therapies for congenital cardiac and skeletal myopathies

      Ochala, Julien & Sun, Y. B., 1 Oct 2016, In: Journal of Medical Genetics. 53, 10, p. 651-654 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Nuclear numbers in syncytial muscle fibers promote size but limit the development of larger myonuclear domains

      Cramer, A. A. W., Prasad, V., Eftestøl, E., Song, T., Hansson, K. A., Dugdale, H. F., Sadayappan, S., Ochala, Julien, Gundersen, K. & Millay, D. P., 2020, In: Nature Communications. 11, 1, 14 p., 6287.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      PGC-1α regulates myonuclear accretion after moderate endurance training

      Battey, E., Furrer, R., Ross, J., Handschin, C., Ochala, Julien & Stroud, M. J., 2022, In: Journal of Cellular Physiology. 237, 1, p. 696-705

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Physical activity impacts resting skeletal muscle myosin conformation and lowers its ATP consumption

      Lewis, C. T. A., Tabrizian, L., Nielsen, J., Laitila, J., Beck, T. N., Olsen, M. S., Ognjanovic, M. M., Aagaard, P., Hokken, R., Laugesen, S., Ingersen, A., Andersen, J. L., Soendenbroe, C., Helge, J. W., Dela, F., Larsen, S., Sahl, R. E., Rømer, T., Hansen, M. T., Frandsen, J. & 2 others, Suetta, Charlotte & Ochala, Julien, 2023, In: The Journal of general physiology. 155, 7, 8 p., e202213268.

      Research output: Contribution to journal › Journal article › Research › peer-review

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