Jens Juul Holst

Jens Juul Holst

Professor


  1. 2015
  2. Published

    Measurement of the incretin hormones: glucagon-like peptide-1 and glucose-dependent insulinotropic peptide

    Kuhre, Rune Ehrenreich, Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette, Deacon, Carolyn F. & Holst, Jens Juul, Apr 2015, In: Journal of Diabetes and its Complications. 29, 3, p. 445-450 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Patients with psoriasis are insulin resistant

    Gyldenløve, M., Storgaard, H., Holst, Jens Juul, Vilsbøll, T., Knop, Filip Krag & Skov, Lone, Apr 2015, In: Journal of the American Academy of Dermatology. 72, 4, p. 599-605 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    The effects of TNF-α on GLP-1-stimulated plasma glucose kinetics

    Lehrskov-Schmidt, L., Lehrskov-Schmidt, L., Nielsen, S. T., Holst, Jens Juul, Møller, K. & Solomon, T. P. J., Apr 2015, In: The Journal of clinical endocrinology and metabolism. 100, 4, p. E616-E622 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Immediate enhancement of first-phase insulin secretion and unchanged glucose effectiveness in patients with type 2 diabetes after Roux-en-Y gastric bypass

    Martinussen, C., Bojsen-Moller, K. N., Dirksen, C., Jacobsen, S. H., Jørgensen, N. B., Kristiansen, V. B., Holst, Jens Juul & Madsbad, Sten, 15 Mar 2015, In: American Journal of Physiology: Endocrinology and Metabolism. 308, 6, p. E535-44 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    An Analysis of Cosecretion and Coexpression of Gut Hormones From Male Rat Proximal and Distal Small Intestine

    Svendsen, B., Pedersen, Jens, Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette, Toräng, S., Rehfeld, Jens Frederik, Poulsen, Steen Seier & Holst, Jens Juul, Mar 2015, In: Endocrinology. 156, 3, p. 847-857 11 p., en20141710.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Clearance of glucoregulatory peptide hormones during haemodialysis and haemodiafiltration in non-diabetic end-stage renal disease patients

    Jørgensen, M. B., Idorn, T., Knop, Filip Krag, Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, Mar 2015, In: Nephrology, Dialysis, Transplantation. 30, 3, p. 513-20 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Improvements in glucose metabolism early after gastric bypass surgery are not explained by increases in total bile acids and fibroblast growth factor 19 concentrations

    Jørgensen, N. B., Dirksen, C., Bojsen-Møller, K. N., Kristiansen, V. B., Wulff, B. S., Rainteau, D., Humbert, L., Rehfeld, Jens Frederik, Holst, Jens Juul, Madsbad, Sten & Clausen, T. R., Mar 2015, In: The Journal of clinical endocrinology and metabolism. 100, 3, p. E396-406 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Incretin effect after oral amino Acid ingestion in humans

    Lindgren, O., Pacini, G., Tura, A., Holst, Jens Juul, Deacon, Carolyn F. & Ahrén, B., Mar 2015, In: The Journal of clinical endocrinology and metabolism. 100, 3, p. 1172-6 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    GLP-1 defects in diabetes

    Janus, C., Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2 Feb 2015

    Research output: Other contributionNet publication - Internet publicationResearchpeer-review

  11. Published

    In vivo efficacy of HD0471953: A novel GPR119 agonist for the treatment of type 2 diabetes mellitus

    'T Hart, L. M., Fritsche, A., Nijpels, G., Van Leeuwen, N., Donnelly, L. A., Dekker, J. M., Alssema, M., Fadista, J., Carlotti, F., Gjesing, A. P., Palmer, C. N., Van Haeften, T. W., Herzberg-Schäfer, S. A., Simonis-Bik, A. M., Houwing-Duistermaat, J. J., Helmer, Q., Deelen, J., Guigas, B., Hansen, T., MacHicao, F. & 14 others, Willemsen, G., Heine, R. J., Kramer, M. H., Holst, Jens Juul, De Koning, E. J., Häring, H. U., Pedersen, O., Groop, L., De Geus, E. J., Slagboom, P. E., Boomsma, D. I., Eekhoff, E. M., Pearson, E. R. & Diamant, M., 1 Feb 2015, In: Diabetes Technology & Therapeutics. 17, p. S131-S133

    Research output: Contribution to journalComment/debateResearchpeer-review

  12. Published

    Effects of acute exercise on pancreatic endocrine function in subjects with type 2 diabetes

    Knudsen, S. H., Karstoft, K., Winding, K., Holst, Jens Juul, Pedersen, Bente Klarlund & Solomon, T., Feb 2015, In: Diabetes, Obesity and Metabolism. 17, 2, p. 207-210 4 p.

    Research output: Contribution to journalLetterResearchpeer-review

  13. Published

    Molecular Mechanisms of Glucose-Stimulated GLP-1 Secretion From Perfused Rat Small Intestine

    Kuhre, Rune Ehrenreich, Frost, C. R., Svendsen, B. & Holst, Jens Juul, Feb 2015, In: Diabetes. 64, 2, p. 370-382 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Updates in weight loss surgery and gastrointestinal peptides

    Svane, M. S., Bojsen-Møller, K. N., Madsbad, Sten & Holst, Jens Juul, Feb 2015, In: Current Opinion in Endocrinology, Diabetes and Obesity. 22, 1, p. 21-8 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  15. Published

    The VGF-Derived Neuropeptide TLQP-21 Shows No Impact on Hormone Secretion in the Isolated Perfused Rat Pancreas

    Christiansen, Charlotte Bayer, Svendsen, B. & Holst, Jens Juul, 20 Jan 2015, In: Hormone and Metabolic Research. 47, 07, p. 537-43 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Sensing of triacylglycerol in the gut: different mechanisms for fatty acids and 2-monoacylglycerol

    Kleberg, K., Jacobsen, A. K., Ferreira, J. G., Windeløv, Johanne Agerlin, Rehfeld, Jens Frederik, Holst, Jens Juul, de Araujo, I. E. & Hansen, Harald S., 16 Jan 2015, In: The Journal of Physiology. 593, 8, p. 2097-109 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Stability of glucagon-like peptide-1 and glucagon in human plasma

    Albrechtsen, Nicolai Jacob Wewer, Bak, M. J., Hartmann, Bolette, Christensen, L. W., Kuhre, Rune Ehrenreich, Deacon, Carolyn F. & Holst, Jens Juul, 16 Jan 2015, In: Endocrine Connections. 4, 1, p. 50-57 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Effect of moderate- and high-intensity acute exercise on appetite in obese individuals

    Martins, C., Stensvold, D., Finlayson, G., Holst, Jens Juul, Wisloff, U., Kulseng, B., Morgan, L. & King, N. A., Jan 2015, In: Medicine and Science in Sports and Exercise. 47, 1, p. 40-8 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Glucose-Dependent Insulinotropic Polypeptide Augments Glucagon Responses to Hypoglycemia in Type 1 Diabetes

    Christensen, Mikkel Bring, Calanna, S., wbf943, wbf943, Kristensen, P. L., Rosenkilde, Mette, Faber, Jens, Purrello, F., van Hall, Gerrit, Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, Jan 2015, In: Diabetes. 64, 1, p. 72-78 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Restoration of the insulinotropic effect of glucose-dependent insulinotropic polypeptide contributes to the antidiabetic effect of dipeptidyl peptidase-4 inhibitors

    Aaboe, K., Akram, S., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten & Krarup, T., Jan 2015, In: Diabetes, Obesity and Metabolism. 17, 1, p. 74-81 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Bile Acids Trigger GLP-1 Release Predominantly by Accessing Basolaterally Located G Protein-Coupled Bile Acid Receptors

    Brighton, C. A., Rievaj, J., Kuhre, Rune Ehrenreich, Glass, L. L., Schoonjans, K., Holst, Jens Juul, Gribble, F. M. & Reimann, F., 2015, In: Endocrinology. 156, 11, p. 3961-1370 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Bile acid mediated effects on gut integrity and performance of early-weaned piglets

    de Diego-Cabero, N., Mereu, A., Menoyo, D., Holst, Jens Juul & Ipharraguerre, I. R., 2015, In: B M C Veterinary Research. 11, 1, p. 1-8 8 p., 111.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Differential effects of glucagon-like peptide-1 on microvascular recruitment and glucose metabolism in short- and long-term Insulin resistance

    Sjøberg, K. A., Rattigan, S., Jeppesen, J. F., Lundsgaard, Anne-Marie, Holst, Jens Juul & Kiens, Bente, 2015, In: Journal of Physiology. 593, 9, p. 2185-2198 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Dual-hormone treatment with insulin and glucagon in patients with type 1 diabetes

    Reiband, H. K., Schmidt, S., Ranjan, A., Holst, Jens Juul, Madsbad, Sten & Nørgaard, Kirsten, 2015, In: Diabetes - Metabolism: Research and Reviews (Print Edition). 31, 7, p. 672-9 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  25. Published

    Early gradual feeding with bovine colostrum improves gut function and NEC resistance relative to infant formula in preterm pigs

    Shen, René Liang, Thymann, Thomas, Østergaard, M. V., Støy, A. C. F., Krych, Lukasz, Nielsen, Dennis Sandris, Lauridsen, C., Hartmann, Bolette, Holst, Jens Juul, Burrin, D. G. & Sangild, Per Torp, 2015, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 309, 5, p. G310-G323 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Early phase glucagon and insulin secretory abnormalities, but not incretin secretion, are similarly responsible for hyperglycemia after ingestion of nutrients

    Yabe, D., Kuroe, A., Watanabe, K., Iwasaki, M., Hamasaki, A., Hamamoto, Y., Harada, N., Yamane, S., Lee, S., Murotani, K., Deacon, Carolyn F., Holst, Jens Juul, Hirano, T., Inagaki, N., Kurose, T. & Seino, Y., 2015, In: Journal of Diabetes and its Complications. 29, p. 413-421 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Effect of Oxyntomodulin, Glucagon, GLP-1 and Combined Glucagon +GLP-1 Infusion on Food Intake, Appetite and Resting Energy Expenditure

    Bagger, J. I., Holst, Jens Juul, Hartmann, Bolette, Andersen, B., Knop, Filip Krag & Vilsbøll, T., 2015, In: The Journal of Clinical Endocrinology & Metabolism. 100, 12, p. 4541–4552 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Effect of Roux-en-Y gastric bypass on the distribution and hormone expression of small-intestinal enteroendocrine cells in obese patients with type 2 diabetes

    Rhee, N. A., Wahlgren, C. D., Pedersen, J., Mortensen, B., Langholz, E., Wandall, E. P., Friis, S. U., Vilmann, Peter, Paulsen, S. J., Kristiansen, V. B., Jelsing, J., Dalbøge, L. S., Poulsen, Steen Seier, Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, 2015, In: Diabetologia. 58, 10, p. 2254-2258 5 p.

    Research output: Contribution to journalLetterResearchpeer-review

  29. Published

    Effects of insulin therapy on weight gain and fat distribution in the HF/HS-STZ rat model of type 2 diabetes

    Skovsø, S., Damgaard, J., Fels, J. J., Olsen, G. S., Wolf, X. A., Rolin, B. & Holst, Jens Juul, 2015, In: International Journal of Obesity. 39, 10, p. 1531-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Efficacy and safety of the glucagon-like peptide-1 receptor agonist liraglutide added to insulin therapy in poorly regulated patients with type 1 diabetes-a protocol for a randomised, double-blind, placebo-controlled study: The Lira-1 study

    Dejgaard, T. F., Knop, Filip Krag, Tarnow, L., Frandsen, C. S., Hansen, T. S., Almdal, Thomas Peter, Holst, Jens Juul, Madsbad, Sten & Andersen, H. U., 2015, In: B M J Open. 5, 4, p. 1-8 8 p., e007791.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Four weeks supplementation with Lactobacillus paracasei subsp. paracasei L. casei W8® shows modest effect on triacylglycerol in young healthy adults

    Bjerg, A. T., Kristensen, M. B., Ritz, C., Stark, K. D., Holst, Jens Juul, Leser, T. D., Wellejus, A. & Astrup, A., 2015, In: Beneficial Microbes. 6, 1, p. 29-39 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    GLP-1 baseret behandling af diabetes og svær overvægt

    Iepsen, E. P. W., Torekov, Signe Sørensen & Holst, Jens Juul, 2015, In: BestPractice. 9, 4, p. 10-12 3 p.

    Research output: Contribution to journalJournal articleCommunication

  33. Published

    GLP-1 receptor agonist treatment increases bone formation and prevents bone loss in weight-reduced obese women

    Iepsen, E. P. W., Lundgren, J. R., Hartmann, Bolette, Pedersen, Oluf Borbye, Hansen, Torben, Jørgensen, Niklas Rye, Jensen, J. B., Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 2015, In: The Journal of clinical endocrinology and metabolism. 100, 8, p. 2909 –2917 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    GLP1 and glucagon co-secreting pancreatic neuroendocrine tumor presenting as hypoglycemia after gastric bypass

    Guimarães, M., Rodrigues, P., Pereira, S. S., Nora, M., Gonçalves, G., Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette, Holst, Jens Juul & Monteiro, M. P., 2015, In: Endocrinology, Diabetes & Metabolism Case Reports. 2015, p. 1-5 5 p., 150049.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Gastric bypass surgery has a weight-loss independent effect on post-challenge serum glucose levels

    Hofsø, D., Birkeland, K. I., Holst, Jens Juul, Bollerslev, J., Sandbu, R., Røislien, J. & Hjelmesæth, J., 2015, In: Diabetology & Metabolic Syndrome. 7, p. 1-4 4 p., 69.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Gastric emptying and disease activity in inflammatory bowel disease

    Keller, J., Binnewies, U., Rösch, M., Holst, Jens Juul, Beglinger, C., Andresen, V. & Layer, P., 2015, In: European Journal of Clinical Investigation. 45, 12, p. 1234-42 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Heterogeneity of glucagonomas due to differential processing of proglucagon-derived peptides

    Challis, B. G., Albrechtsen, Nicolai Jacob Wewer, Bansiya, V., Burling, K., Barker, P., Hartmann, Bolette, Gribble, F., O'Rahilly, S., Holst, Jens Juul & Simpson, H. L., 2015, In: Endocrinology, Diabetes & Metabolism Case Reports. 2015, p. 1-7 7 p., 150105.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Inability to match energy intake with energy expenditure at sustained near-maximal rates of energy expenditure in older men during a 14-d cycling expedition

    Rosenkilde Larsen, M., Morville, T., Riis Andersen, P., Kjær, K., Rasmusen, H., Holst, Jens Juul, Dela, Flemming, Westerterp, K., Sjödin, Anders Mikael & Helge, Jørn Wulff, 2015, In: American Journal of Clinical Nutrition. 102, 6, p. 1398-1405 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Incretin and glucagon levels in adult offspring exposed to maternal diabetes in pregnancy

    Kelstrup, L., Clausen, Tine Dalsgaard, Mathiesen, Elisabeth, Hansen, Torben, Holst, Jens Juul & Damm, Peter, 2015, In: Journal of Clinical Endocrinology and Metabolism. 100, 5, p. 1967-75 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Infrared thermographic assessment of changes in skin temperature during hypoglycaemia in patients with type 1 diabetes

    Sejling, A., Lange, Kai, Frandsen, C. S., Diemar, S. S., Tarnow, L., Faber, Jens, Holst, Jens Juul, Hartmann, Bolette, Hilsted, Linda, Kjaer, T. W., Juhl, C. B., Thorsteinsson, B. & Pedersen-Bjergaard, Ulrik, 2015, In: Diabetologia. 58, p. 1898–1906 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Intake of Lactobacillus reuteri Improves Incretin and Insulin Secretion in Glucose-Tolerant Humans: A Proof of Concept

    Simon, M., Strassburger, K., Nowotny, B., Kolb, H., Nowotny, P., Burkart, V., Zivehe, F., Hwang, J., Stehle, P., Pacini, G., Hartmann, Bolette, Holst, Jens Juul, MacKenzie, C., Bindels, L. B., Martinez, I., Walter, J., Henrich, B., Schloot, N. C. & Roden, M., 2015, In: Diabetes Care. 38, 10, p. 1827-34 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    L-glutamine and whole protein restore first-phase insulin response and increase glucagon-like Peptide-1 in type 2 diabetes patients

    Samocha-Bonet, D., Chisholm, D. J., Holst, Jens Juul & Greenfield, J. R., 2015, In: Nutrients. 7, 4, p. 2101-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Liraglutide for Type 2 diabetes and obesity: a 2015 update

    Iepsen, E. P. W., Torekov, Signe Sørensen & Holst, Jens Juul, 2015, In: Expert Review of Cardiovascular Therapy. 13, 7, p. 753-67 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Post-surgical effects of Roux-En-Y gastric bypass on glucose homeostasis, intestinal morphology and L-cells in obese Göttingen minipigs

    Barkholt, P., Vegge, A., Clausen, T. R., Birck, M. M., Fels, J. J., Støckel, M., Gögenur, Ismail, Eriksen, Thomas, Holst, Jens Juul, Hansen, Axel Kornerup, Thymann, Thomas, Jelsing, J., Sangild, Per Torp & Raun, K., 2015, In: Journal of Obesity and Bariatrics. 1, 1, 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Reduction of insulinotropic properties of GLP-1 and GIP after glucocorticoid-induced insulin resistance

    Eriksen, M., Jensen, D. H., Tribler, S., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 2015, In: Diabetologia. 58, 5, p. 920-8 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Resistant starch and protein intake enhances fat oxidation and feelings of fullness in lean and overweight/obese women

    Gentile, C. L., Ward, E., Holst, Jens Juul, Astrup, A., Ormsbee, M. J., Connelly, S. & Arciero, P. J., 2015, In: Nutrition Journal. 14, 10 p., 113.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Specific inhibition of bile acid transport alters plasma lipids and GLP-1

    Rudling, M., Camilleri, M., Graffner, H., Holst, Jens Juul & Rikner, L., 2015, In: B M C Cardiovascular Disorders. 15, p. 1-8 8 p., 75.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    The 2-monoacylglycerol moiety of dietary fat appears to be responsible for the fat-induced release of GLP-1 in humans.

    Mandøe, M. J., Hansen, K. B., Hartmann, Bolette, Rehfeld, Jens Frederik, Holst, Jens Juul & Hansen, Harald S., 2015, In: The American Journal of Clinical Nutrition. 102, 3, p. 548-555 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    The Use of Gastrostomy Tube for the Long-Term Remission of Hyperinsulinemic Hypoglycemia After Roux-en-y Gastric Bypass: A Case Report

    Craig, C., Lamendola, C., Holst, Jens Juul, Deacon, Carolyn F. & McLaughlin, T., 2015, In: AACE Clinical Case Reports. 1, 2, p. e84-e87 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    The glucagon-like peptide-1 receptor agonist liraglutide reduces jejunostomy output and improves intestinal absorption in short bowel syndrome patients with intestinal failure: A pilot study

    Hvistendahl, M., Brandt, C. F., Tribler, S., Naimi, R., Hartmann, B., Holst, Jens Juul, Rehfeld, Jens Frederik, Hornum, M., Andersen, Jens Rikardt, Mortensen, P. B. & Jeppesen, P. B., 2015. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  51. Published

    The influence of glucagon on postprandial hyperglycaemia in children 5 years after onset of type 1 diabetes

    Fredheim, S., Andersen, M. M., Pörksen, S., Nielsen, L. B., Pipper, C., Hansen, L., Holst, Jens Juul, Thomsen, J., Johannesen, Jesper, Mortensen, H. B. & Svensson, Jannet, 2015, In: Diabetologia. 58, 4, p. 828-34 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Treatment with a GLP-1 receptor agonist diminishes the decrease in free plasma leptin during maintenance of weight loss

    Iepsen, E. W., Lundgren, J., Dirksen, C., Jensen, J., Pedersen, Oluf Borbye, Hansen, Torben, Madsbad, Sten, Holst, Jens Juul & Torekov, Signe Sørensen, 2015, In: International journal of obesity (2005). 39, 5, p. 834-41 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Type 2 diabetes mellitus

    DeFronzo, R. A., Ferrannini, E., Groop, L., Henry, R. R., Herman, W. H., Holst, Jens Juul, Hu, F. B., Kahn, C. R., Raz, I., Shulmann, G. I., Simonson, D. C., Testa, M. A. & Weiss, R., 2015, In: Nature Reviews. Disease Primers. 1, 22 p., 15019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. 2014
  55. Published

    Pancreatic effects of GLP-1

    Kuhre, Rune Ehrenreich, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 22 Dec 2014, Diapedia: The Living Textbook of Diabetes. European Association for the Study of Diabetes (EASD)

    Research output: Chapter in Book/Report/Conference proceedingEncyclopedia chapterCommunication

  56. Published

    The melanocortin-4 receptor is expressed in enteroendocrine L cells and regulates the release of peptide YY and glucagon-like peptide 1 in vivo

    Panaro, B. L., Tough, I. R., Engelstoft, M. S., Matthews, R. T., Digby, G. J., Møller, C. L., Svendsen, B., Gribble, F., Reimann, F., Holst, Jens Juul, Holst, Birgitte, Schwartz, Thue W., Cox, H. M. & Cone, R. D., 2 Dec 2014, In: Cell Metabolism. 20, 6, p. 1018-29 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    On the role of gallbladder emptying and incretin hormones for nutrient-mediated TSH suppression in patients with type 2 diabetes

    Sonne, David Peick, Lund, Asger Bach, Faber, J., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Dec 2014, In: Endocrine Connections. 3, 4, p. 193-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    The interleukin-1 receptor antagonist anakinra improves first-phase insulin secretion and insulinogenic index in subjects with impaired glucose tolerance

    van Poppel, P. C. M., van Asseldonk, E. J. P., Holst, Jens Juul, Vilsbøll, Tina, Netea, M. G. & Tack, C. J., Dec 2014, In: Diabetes, Obesity and Metabolism. 16, 12, p. 1269-73 5 p.

    Research output: Contribution to journalLetterResearchpeer-review

  59. Published

    Therapies for inter-relating diabetes and obesity - GLP-1 and obesity

    Iepsen, E. P. W., Torekov, Signe Sørensen & Holst, Jens Juul, Dec 2014, In: Expert Opinion on Pharmacotherapy. 15, 17, p. 2487-500 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Glucose-dependent insulinotropic polypeptide inhibits bone resorption in humans

    Nissen, A., Christensen, Mikkel Bring, Knop, Filip Krag, Vilsbøll, T., Holst, Jens Juul & Hartmann, Bolette, Nov 2014, In: The Journal of clinical endocrinology and metabolism. 99, 11, p. E2325-9 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    GLP-1 as a Mediator in the Remission of Type 2 Diabetes After Gastric Bypass and Sleeve Gastrectomy Surgery

    Madsbad, Sten & Holst, Jens Juul, Oct 2014, In: Diabetes. 63, 10, p. 3172-4 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Postprandial gallbladder emptying in patients with type 2 diabetes: potential implications for bile-induced secretion of glucagon-like peptide 1

    Sonne, David Peick, Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Oct 2014, In: European Journal of Endocrinology. 171, 4, p. 407-419 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Glucometabolic hormones and cardiovascular risk markers in antipsychotic-treated patients

    Ebdrup, Bjørn, Knop, Filip Krag, Madsen, A., Mortensen, H. B., Søgaard, B., Holst, Jens Juul, Szecsi, P. B. & Lublin, H., Sep 2014, In: Journal of Clinical Psychiatry. 75, 9, p. e899-905 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Safety and efficacy of liraglutide in patients with type 2 diabetes and end-stage renal disease: an investigator-initiated, randomised, placebo-controlled trial

    Idorn, T., Knop, Filip Krag, Jorgensen, M. B., Jensen, T., Resuli, M., Hansen, P. M., Christensen, Karl Bang, Holst, Jens Juul, Hornum, M. & Feldt-Rasmussen, B., Sep 2014, In: Diabetologia. 57, 1 supplement, p. S370-S371 909.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  65. Published

    The use of double-balloon enteroscopy in retrieving mucosal biopsies from the entire human gastrointestinal tract

    Rhee, N. A., Vilmann, Peter, Hassan, H., Hendel, J. W., Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, Sep 2014, In: Scandinavian Journal of Gastroenterology. 49, 9, p. 1143-1149 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    High saturated fatty acid intake induces insulin secretion by elevating gastric inhibitory polypeptide levels in healthy individuals

    Itoh, K., Moriguchi, R., Yamada, Y., Fujita, M., Yamato, T., Oumi, M., Holst, Jens Juul & Seino, Y., Aug 2014, In: Nutrition Research. 34, 8, p. 653-60 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Stimulation of intestinal growth and function with DPP-IV inhibition in a mouse short bowel syndrome model

    Sueyoshi, R., Ignatoski, K. M. W., Okawada, M., Hartmann, Bolette, Holst, Jens Juul & Teitelbaum, D. H., 26 Jun 2014, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 307, 4, p. G410-19 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    The impact of dipeptidyl peptidase 4 inhibition on incretin effect, glucose tolerance, and gastrointestinal-mediated glucose disposal in healthy subjects

    Rhee, N. A., Østoft, S. H., Holst, Jens Juul, Deacon, Carolyn F., Vilsbøll, T. & Knop, Filip Krag, 16 Jun 2014, In: European Journal of Endocrinology. 171, 3, p. 353-362 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Glucose-Lowering Effects and Low Risk of Hypoglycemia in Patients With Maturity-Onset Diabetes of the Young When Treated With a GLP-1 Receptor Agonist: A Double-Blind, Randomized, Crossover Trial

    Ostoft, S. H., Bagger, J. I., Hansen, Torben, Pedersen, Oluf Borbye, Faber, Jens, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, T., 14 Jun 2014, In: Diabetes Care. 37, 7, p. 1797-1805 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Incretin secretion: direct mechanisms

    Balk-Møller, E., Holst, Jens Juul & Kuhre, Rune Ehrenreich, 12 Jun 2014, Diapedia: The living textbook of diabetes. European Association for the Study of Diabetes (EASD), p. 1-3 3 p.

    Research output: Chapter in Book/Report/Conference proceedingEncyclopedia chapterCommunication

  71. Published

    Hyperglucagonaemia analysed by glucagon sandwich ELISA: nonspecific interference or truly elevated levels?

    Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette, Veedfald, Simon, Windeløv, Johanne Agerlin, Plamboeck, A., Bojsen-Møller, K. N., Idorn, T., Feldt-Rasmussen, Bo, Knop, Filip Krag, Vilsbøll, T., Madsbad, Sten, Deacon, Carolyn F. & Holst, Jens Juul, 3 Jun 2014, In: Diabetologia. 57, 9, p. 1919-1926 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    Glucose Stimulates GLP-1 Secretion from Isolated Perfused Rat Small Intestine by SGLT1 and GLUT2 Mediated Uptake, Causing V-gated Calcium Channel Activation

    Kuhre, Rune Ehrenreich, Frost, C. R., Svendsen, B. & Holst, Jens Juul, Jun 2014, In: Diabetes. 63, suppl 1, p. A491 1 p., Abstract no 1915-P.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  73. Published

    Glucagon responses to increasing oral loads of glucose and corresponding isoglycaemic intravenous glucose infusions in patients with type 2 diabetes and healthy individuals

    Bagger, J. I., Knop, Filip Krag, Lund, Asger Bach, Holst, Jens Juul & Vilsbøll, T., 31 May 2014, In: Diabetologia. 57, 8, p. 1270-25 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Acute effects of monounsaturated fat on postprandial lipemia and gene expression in first-degree relatives of subjects with type 2 diabetes

    Pietraszek, A., Gregersen, S., Pedersen, S. B., Holst, Jens Juul & Hermansen, K., 14 May 2014, In: European Journal of Clinical Nutrition. 68, p. 1022-28 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Dose response of continuous subcutaneous infusion of recombinant glucagon-like peptide-1 in combination with metformin and sulphonylurea over 12 weeks in patients with type 2 diabetes mellitus

    Torekov, Signe Sørensen, Holst, Jens Juul & Ehlers, M. R., May 2014, In: Diabetes, Obesity and Metabolism. 16, 5, p. 451-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Glutamate prevents intestinal atrophy via luminal nutrient sensing in a mouse model of total parenteral nutrition

    Xiao, W., Feng, Y., Holst, Jens Juul, Hartmann, Bolette, Yang, H. & Teitelbaum, D. H., May 2014, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 28, 5, p. 2073-87 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Postprandial effects of test meals including concentrated arabinoxylan and whole grain rye in subjects with the metabolic syndrome: a randomised study

    Hartvigsen, M. L., Lærke, H. N., Overgaard, A., Holst, Jens Juul, Bach Knudsen, K. E. & Hermansen, K., May 2014, In: European Journal of Clinical Nutrition. 68, 5, p. 567-74 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Elimination and degradation of glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in patients with end-stage renal disease

    Idorn, T., Knop, Filip Krag, Jørgensen, M. B., Christensen, Mikkel Bring, Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, 8 Apr 2014, In: The Journal of clinical endocrinology and metabolism. 99, 7, p. 2457-66 10 p., jc20133809.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Effect of IL-6 on the insulin sensitivity in patients with type 2 diabetes

    Harder-Lauridsen, N. M., Krogh-Madsen, Rikke, Holst, Jens Juul, Plomgaard, P., Leick, L., Pedersen, Bente Klarlund & Fischer, C. P., 1 Apr 2014, In: American Journal of Physiology: Endocrinology and Metabolism. 306, 7, p. E769-78 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    Fructose stimulates GLP-1 but not GIP secretion in mice, rats, and humans

    Kuhre, Rune Ehrenreich, Gribble, F. M., Hartmann, Bolette, Reimann, F., Windeløv, Johanne Agerlin, Rehfeld, Jens Frederik & Holst, Jens Juul, 1 Apr 2014, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 306, 7, p. G622-30 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    A functional amino acid substitution in the glucose-dependent insulinotropic polypeptide receptor (GIPR) gene is associated with lower bone mineral density and increased fracture risk

    Torekov, Signe Sørensen, Harsløf, T., Rejnmark, L., Eiken, P., Jensen, Jens-Erik Beck, Herman, A. P., Hansen, Torben, Pedersen, Oluf Borbye, Holst, Jens Juul & Langdahl, B. L., Apr 2014, In: The Journal of clinical endocrinology and metabolism. 99, 4, p. E729-33 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Impact of oral vancomycin on gut microbiota, bile acid metabolism, and insulin sensitivity

    Vrieze, A., Out, C., Fuentes, S., Jonker, L., Reuling, I., Kootte, R. S., van Nood, E., Holleman, F., Knaapen, M., Romijn, J. A., Soeters, M. R., Blaak, E. E., Dallinga-Thie, G. M., Reijnders, D., Ackermans, M. T., Serlie, M. J., Knop, F. K., Holst, J. J., van der Ley, C., Kema, I. P. & 6 others, Zoetendal, E. G., de Vos, W. M., Hoekstra, J. B. L., Stroes, E. S., Groen, A. K. & Nieuwdorp, M., Apr 2014, In: Journal of Hepatology. 60, 4, p. 824-31 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    KCNQ1 Long QT syndrome patients have hyperinsulinemia and symptomatic hypoglycemia

    Torekov, Signe Sørensen, Iepsen, E., Christiansen, M., Linneberg, Allan René, Pedersen, Oluf Borbye, Holst, Jens Juul, Kanters, Jørgen K. & Hansen, Torben, Apr 2014, In: Diabetes. 63, 4, p. 1315-1325 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Incretin Effect and Glucagon Responses to Oral and Intravenous Glucose in Patients with Maturity Onset Diabetes of the Young - Type 2 and Type 3

    Ostoft, S. H., Bagger, J. I., Hansen, Torben, Pedersen, Oluf Borbye, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, T., 27 Mar 2014, In: Diabetes. 63, 8, p. 2838-44 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Similar weight-adjusted insulin secretion and insulin sensitivity in short-duration late autoimmune diabetes of adulthood (LADA) and Type 2 diabetes: Action LADA 8

    Juhl, C. B., Bradley, U., Holst, Jens Juul, Leslie, R. D., Yderstraede, K. B., Hunter, S. & Action LADA Consortium, A. L. C., 15 Mar 2014, In: Diabetic Medicine. 31, 8, p. 941-945

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Defining the role of GLP-1 in the enteroinsulinar axis in type 2 diabetes using DPP-4 inhibition and GLP-1 receptor blockade

    Aulinger, B. A., Bedorf, A., Kutscherauer, G., de Heer, J., Holst, Jens Juul, Göke, B. & Schirra, J., Mar 2014, In: Diabetes. 63, 3, p. 1079-92 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Glucose-dependent Insulinotropic Polypeptide: Blood Glucose Stabilizing Effects in Patients With Type 2 Diabetes

    Christensen, Mikkel Bring, Calanna, S., Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, Mar 2014, In: The Journal of clinical endocrinology and metabolism. 99, 3, p. E418-26 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Insulin resistance alters islet morphology in nondiabetic humans

    Mezza, T., Muscogiuri, G., Sorice, G. P., Clemente, G., Hu, J., Pontecorvi, A., Holst, Jens Juul, Giaccari, A. & Kulkarni, R. N., Mar 2014, In: Diabetes. 63, 3, p. 994-1007 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    The incretin effect does not differ in trained and untrained, young, healthy men

    Lund, M. T., Dalby, S., Hartmann, Bolette, Helge, Jørn Wulff, Holst, Jens Juul & Dela, Flemming, Mar 2014, In: Acta Physiologica. 210, 3, p. 565-72 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Effects of sitagliptin and metformin treatment on incretin hormone and insulin secretory responses to oral and "isoglycemic" intravenous glucose

    Vardarli, I., Arndt, E., Deacon, Carolyn F., Holst, Jens Juul & Nauck, M. A., Feb 2014, In: Diabetes. 63, 2, p. 663-74 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Impact of the reconstruction method on delayed gastric emptying after pylorus-preserving pancreaticoduodenectomy: a prospective randomized study

    Tamandl, D., Sahora, K., Prucker, J., Schmid, R., Holst, J., Miholic, J., Goetzinger, P., Gnant, M. & Holst, Jens Juul, Feb 2014, In: World Journal of Surgery. 38, 2, p. 465-75 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Mechanisms of changes in glucose metabolism and bodyweight after bariatric surgery

    Madsbad, Sten, Dirksen, C. & Holst, Jens Juul, Feb 2014, In: The Lancet Diabetes & Endocrinology. 2, 2, p. 152-64 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    GLP-1 Amidation Efficiency Along the Length of the Intestine in Mice, Rats and Pigs and in GLP-1 Secreting Cell Lines

    Kuhre, Rune Ehrenreich, Albrechtsen, Nicolai Jacob Wewer, Windeløv, Johanne Agerlin, Svendsen, B., Hartmann, Bolette & Holst, Jens Juul, 31 Jan 2014, In: Peptides. 55, p. 52-57 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Effects of chronic glucagon-like peptide-2 therapy during weaning in neonatal pigs

    Sigalet, D. L., de Heuvel, E., Wallace, L., Bulloch, E., Turner, J., Wales, P. W., Nation, P., Wizzard, P. R., Hartmann, Bolette, Assad, M. & Holst, Jens Juul, 10 Jan 2014, In: Regulatory Peptides. 188, p. 70-80 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Targeting the intestinal L-cell for obesity and type 2 diabetes treatment

    Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Deacon, Carolyn F. & Holst, Jens Juul, 1 Jan 2014, In: Expert Review of Endocrinology & Metabolism. 9, 1, p. 61-72 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    Distal gastrectomy in pancreaticoduodenectomy is associated with accelerated gastric emptying, enhanced postprandial release of GLP-1, and improved insulin sensitivity

    Harmuth, S., Wewalka, M., Holst, Jens Juul, Nemecek, R., Thalhammer, S., Schmid, R., Sahora, K., Gnant, M. & Miholić, J., Jan 2014, In: Journal of Gastrointestinal Surgery. 18, 1, p. 52-9 8 p.

    Research output: Contribution to journalConference articleResearchpeer-review

  97. Published

    Effects of concentrated arabinoxylan and β-glucan compared with refined wheat and whole grain rye on glucose and appetite in subjects with the metabolic syndrome: a randomized study

    Hartvigsen, M. L., Gregersen, S., Lærke, H. N., Holst, Jens Juul, Bach Knudsen, K. E. & Hermansen, K., Jan 2014, In: European Journal of Clinical Nutrition. 68, 1, p. 84-90 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    GLP-1 responses are heritable and blunted in acquired obesity with high liver fat and insulin resistance

    Matikainen, N., Bogl, L. H., Hakkarainen, A., Lundbom, J., Lundbom, N., Kaprio, J., Rissanen, A., Holst, Jens Juul & Pietiläinen, K. H., Jan 2014, In: Diabetes Care. 37, 1, p. 242-51 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Postprandial responses of incretin and pancreatic hormones in non-diabetic patients with end-stage renal disease

    Idorn, T., Knop, Filip Krag, Jørgensen, M., Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, Jan 2014, In: Nephrology, Dialysis, Transplantation. 29, 1, p. 119-27 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    The authors reply

    Idorn, T., Knop, Filip Krag, Jørgensen, M., Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, Jan 2014, In: Kidney International. 85, 1, p. 212-3 2 p.

    Research output: Contribution to journalLetterResearchpeer-review

  101. Published

    A 25-year-old woman with type 2 diabetes and liver disease

    Junker, A. E., Gluud, Lise Lotte, Pedersen, J., Langhoff, J. L., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, T., 2014, In: Case Reports in Gastroenterology. 8, 3, p. 398-403 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  102. Published

    Consumption of a diet low in advanced glycation end products for 4 weeks improves insulin sensitivity in overweight women

    Mark, A. B., Poulsen, M. W., Andersen, S., Andersen, J. M., Bak, M. J., Ritz, C., Holst, Jens Juul, Nielsen, J., de Courten, B., Dragsted, Lars Ove & Bügel, Susanne Gjedsted, 2014, In: Diabetes Care. 37, 1, p. 88-95 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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