Jens Juul Holst

Jens Juul Holst

Professor

ORCID: 0000-0001-6853-3805

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  1. Published

    Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production

    Albrechtsen, N. J. W., Kuhre, R. E., Hornburg, D., Jensen, C. Z., Hornum, M., Dirksen, C., Svane, M., Gasbjerg, L. S., Jorgensen, N. B., Gabe, M. N., Balk-Moller, E., Albrechtsen, R., Winther-Sorensen, M., Galsgaard, K. D., Meissner, F., Jorsal, T., Lund, A., Vilsboll, T., Eliasen, R., Bojsen-Moller, K. N. & 9 others, Idorn, T., Deacon, Carolyn F., Knop, Filip Krag, Rosenkilde, Mette, Hartmann, Bolette, Feldt-Rasmussen, Bo, Mann, Matthias, Madsbad, Sten & Holst, Jens Juul, Nov 2017, In: Cell Reports. 21, 6, p. 1452-1460

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Stability of glucagon-like peptide-1 and glucagon in human plasma

    Albrechtsen, Nicolai Jacob Wewer, Bak, M. J., Hartmann, Bolette, Christensen, L. W., Kuhre, Rune Ehrenreich, Deacon, Carolyn F. & Holst, Jens Juul, 16 Jan 2015, In: Endocrine Connections. 4, 1, p. 50-57 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Targeting the intestinal L-cell for obesity and type 2 diabetes treatment

    Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Deacon, Carolyn F. & Holst, Jens Juul, 1 Jan 2014, In: Expert Review of Endocrinology & Metabolism. 9, 1, p. 61-72 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Dynamics of glucagon secretion in mice and rats revealed using a validated sandwich ELISA for small sample volumes.

    Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Windeløv, Johanne Agerlin, Ørgaard, A., Deacon, Carolyn F., Kissow, Hannelouise, Hartmann, Bolette & Holst, Jens Juul, 2016, In: American Journal of Physiology: Endocrinology and Metabolism. 311, 2, p. E302-E309 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Glucagon-like peptide-1 receptor signaling in acinar cells causes growth dependent release of pancreatic enzymes

    Albrechtsen, Nicolai Jacob Wewer, Albrechtsen, Reidar, Bremholm, L., Svendsen, B., Kuhre, Rune Ehrenreich, Poulsen, Steen Seier, Christiansen, Charlotte Bayer, Jensen, E. P., Janus, C., Hilsted, Linda, Deacon, Carolyn F., Hartmann, Bolette & Holst, Jens Juul, 2016, In: Cell Reports. 17, 11, p. 2845-2856 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    The intestinal distribution pattern of appetite- and glucose regulatory peptides in mice, rats and pigs

    Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Toräng, S. & Holst, Jens Juul, 2 Feb 2016, In: BMC Research Notes. 9, 1, p. 1-6 6 p., 60.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Hyperglucagonaemia analysed by glucagon sandwich ELISA: nonspecific interference or truly elevated levels?

    Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette, Veedfald, Simon, Windeløv, Johanne Agerlin, Plamboeck, A., Bojsen-Møller, K. N., Idorn, T., Feldt-Rasmussen, Bo, Knop, Filip Krag, Vilsbøll, T., Madsbad, Sten, Deacon, Carolyn F. & Holst, Jens Juul, 3 Jun 2014, In: Diabetologia. 57, 9, p. 1919-1926 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Proglucagon peptide secretion profiles in type 2 diabetes before and after bariatric surgery: 1-year prospective study

    Alexiadou, K., Cuenco, J., Howard, J., Albrechtsen, Nicolai Jacob Wewer, Ilesanmi, I., Kamocka, A., Tharakan, G., Behary, P., Bech, P. R., Ahmed, A. R., Purkayastha, S., Wheller, R., Fleuret, M., Holst, Jens Juul, Bloom, S. R., Khoo, B. & Tan, T. M. M., 2020, In: B M J Open Diabetes Research & Care. 8, 1, 10 p., e001076.

    Research output: Contribution to journal › Review › Research › peer-review

  9. Published

    The T-allele of TCF7L2 rs7903146 associates with a reduced compensation of insulin secretion for insulin resistance induced by 9 days of bed rest

    Alibegovic, A. C., Sonne, M. P., Højbjerre, L., Hansen, T., Pedersen, Oluf Borbye, van Hall, Gerrit, Holst, Jens Juul, Stallknecht, Bente Merete, Dela, Flemming & Vaag, A., 2010, In: Diabetes. 59, 4, p. 836-43 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Glucagon immunoneutralization in diabetic rats normalizes urea synthesis and decreases nitrogen wasting

    Almdal, T. P., Holst, Jens Juul & Vilstrup, H., 1992, In: Diabetes. 41, p. 12-16

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Genetic determinants of circulating GIP and GLP-1 concentrations

    Almgren, P., Lindqvist, A., Krus, U., Hakaste, L., Ottosson-Laakso, E., Asplund, O., Sonestedt, E., Prasad, R. B., Laurila, E., Orho-Melander, M., Melander, O., Tuomi, T., Holst, Jens Juul, Nilsson, P. M., Wierup, N., Groop, L. & Ahlqvist, E., 2 Nov 2017, In: JCI insight. 2, 21, 13 p., e93306.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Discovery of amino acid variants in the human glucose-dependent insulinotropic polypeptide (GIP) receptor: the impact on the pancreatic beta cell responses and functional expression studies in CHL cells

    Almind, K., Ambye, L., Urhammer, S. A., Hansen, T., Echwald, S. M., Holst, Jens Juul, Gromada, J. L., Thorens, B. & Pedersen, O., 1998, In: Diabetologia. 41, p. 1194-1198

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Preserved GLP-1 and exaggerated GIP secretion in type 2 diabetes and relationships with triglycerides and ALT

    Alssema, M., Rijkelijkhuizen, J. M., Holst, Jens Juul, Teerlink, T., Scheffer, P. G., Eekhoff, E. M. W., Gastaldelli, A., Mari, A., Hart, L. M., Nijpels, G. & Dekker, J. M., Oct 2013, In: European Journal of Endocrinology. 169, 4, p. 421-30 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Effects of a self-prepared carbohydrate-reduced high-protein diet on cardiovascular disease risk markers in patients with type 2 diabetes

    Alzahrani, A. H., Skytte, M. J., Samkani, A., Thomsen, M. N., Astrup, A., Ritz, C., Frystyk, J., Holst, Jens Juul, Madsbad, Sten, Haugaard, Steen Bendix, Krarup, T., Larsen, T. M. & Magkos, Faidon, 2021, In: Nutrients. 13, 5, 10 p., 1694.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Body weight and metabolic risk factors in patients with type 2 diabetes on a self-selected high-protein low-carbohydrate diet

    Alzahrani, A. H. A., Skytte, M. J., Samkani, A., Thomsen, M. N., Astrup, A., Ritz, C., Chabanova, E., Frystyk, J., Holst, Jens Juul, Thomsen, Henrik S., Madsbad, Sten, Haugaard, Steen Bendix, Krarup, T., Larsen, T. M. & Magkos, Faidon, 2021, In: European Journal of Nutrition. 60, 8, p. 4473-4482 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Functional ontogeny of the proglucagon-derived peptide axis in the premature human neonate

    Amin, H., Holst, Jens Juul, Hartmann, B., Wallace, L., Wright, J. & Sigalet, D. L., 2008, In: Pediatrics. 121, 1, p. E180-E186 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Functional ontogeny of the proglucagon-derived peptide axis in the premature human neonate

    Amin, H., Holst, Jens Juul, Hartmann, Bolette, Wallace, L., Wright, J. & Sigalet, D. L., Jan 2008, In: Pediatrics. 121, 1, p. e180-6

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    The impact of acute glycaemic fluctuations on left ventricular systolic function in insulin-treated type 2 diabetes

    Andersen, A., Jorgensen, P. G., Bagger, J. I., Baldassarre, M. P. A., Christensen, M., Abelin, K. U., Faber, Jens, Pedersen-Bjergaard, Ulrik, Holst, Jens Juul, Lindhardt, T., Gislason, Gunnar Hilmar, Knop, Filip Krag & Vilsbøll, Tina, 2020, In: Diabetologia. 63, SUPPL 1, p. S429-S429 897.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  19. Published

    Acute hypoglycemia and risk of cardiac arrhythmias in insulin-treated type 2 diabetes and controls

    Andersen, A., Bagger, J. I., Baldassarre, M. P., Christensen, Mikkel Bring, Abelin, K. U., Faber, Jens, Pedersen-Bjerregaard, U., Holst, Jens Juul, Lindhardt, T. B., Gislason, Gunnar Hilmar, Knop, Filip Krag & Vilsbøll, Tina, 2021, In: European Journal of Endocrinology. 185, 2, p. 343-353 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Peptides in the regulation of glucagon secretion

    Andersen, Daniel Bjørklund & Holst, Jens Juul, 2022, In: Peptides. 148, 19 p., 170683.

    Research output: Contribution to journal › Review › Research › peer-review

  21. Published

    Using a Reporter Mouse to Map Known and Novel Sites of GLP-1 Receptor Expression in Peripheral Tissues of Male Mice

    Andersen, Daniel Bjørklund, Grunddal, Kaare Villum, Pedersen, Jens, Kuhre, Rune Ehrenreich, Lund, M. L., Holst, Jens Juul & Ørskov, Cathrine, 2021, In: Endocrinology. 162, 3, bqaa246.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Sperm count is increased by diet-induced weight loss and maintained by exercise or GLP-1 analogue treatment: a randomized controlled trial

    Andersen, E., Juhl, C. R., Kjøller, E. T., Lundgren, J. R., Janus, C., Dehestani, Y., Saupstad, M., Ingerslev, L. R., Duun, O. M., Jensen, Simon Birk Kjær, Holst, Jens Juul, Stallknecht, Bente Merete, Madsbad, Sten, Torekov, Signe Sørensen & Barrès, Romain, May 2022, In: Human Reproduction. 37, 7, p. 1414–1422 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Is glucagon‐like peptide‐1 fully protected by the dipeptidyl peptidase 4 inhibitor sitagliptin when administered to patients with type 2 diabetes?

    Andersen, E. S., Lund, A., Bagger, J. I., Andreasen, C., Grøndahl, M., Deacon, Carolyn F., Hartmann, Bolette, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, Aug 2018, In: Diabetes, Obesity and Metabolism. 20, 8, p. 1937-1943

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Do we know the true mechanism of action of the DPP-4 inhibitors?

    Andersen, E. S., Deacon, Carolyn F. & Holst, Jens Juul, 2018, In: Diabetes, Obesity and Metabolism. 20, 1, p. 34-41 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Enhanced glucagon-like peptide-1 (GLP-1) response to oral glucose in glucose-intolerant HIV-infected patients on antiretroviral therapy

    Andersen, Ove, Haugaard, Steen Bendix, Holst, Jens Juul, Deacon, Carolyn F., Iversen, J., Andersen, U. B., Nielsen, J. O. & Madsbad, Sten, Mar 2005, In: HIV Medicine. 6, 2, p. 91-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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