Clare Louise Hawkins
Professor MSO
Inflammation, Metabolism and Oxidation
Blegdamsvej 3
2200 København N.
- Published
Hypochlorite and superoxide radicals can act synergistically to induce fragmentation of hyaluronan and chondroitin sulphates
Rees, M. D., Hawkins, Clare Louise & Davies, Michael J., 1 Jul 2004, In: Biochemical Journal. 381, Pt 1, p. 175-84 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypochlorite-mediated fragmentation of hyaluronan, chondroitin sulfates, and related N-acetyl glycosamines: evidence for chloramide intermediates, free radical transfer reactions, and site-specific fragmentation
Rees, M. D., Hawkins, Clare Louise & Davies, Michael J., 12 Nov 2003, In: Journal of the American Chemical Society. 125, 45, p. 13719-33 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of hypochlorous acid (HOCl) and other inflammatory mediators in the induction of macrophage extracellular trap formation
Rayner, B. S., Zhang, Y., Brown, B. E., Reyes, L., Cogger, V. C. & Hawkins, Clare Louise, 2018, In: Free Radical Biology and Medicine. 129, p. 25-34Research output: Contribution to journal › Journal article › Research › peer-review
Comparative reactivity of myeloperoxidase-derived oxidants with mammalian cells
Rayner, B. S., Love, D. T. & Hawkins, Clare Louise, Jun 2014, In: Free Radical Biology & Medicine. 71, p. 240-55 16 p.Research output: Contribution to journal › Journal article › Commissioned › peer-review
- Published
MODULATION OF ENDOTHELIAL CELL FUNCTION BY THE MYELOPEROXIDASE-DERIVED OXIDANT HYPOCHLOROUS ACID (HOCl) AND ITS CONTRIBUTION TO ATHEROSCLEROSIS
Rayner, B. S., Lloyd, M. M., Summers, F. A., Davies, Michael J. & Hawkins, Clare Louise, 2014, In: Hypertension.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of macrophage extracellular traps in innate immunity and inflammatory disease
Rasmussen, K. H. & Hawkins, Clare Louise, 2022, In: Biochemical Society Transactions. 50, 1, p. 21-32 12 p.Research output: Contribution to journal › Review › Research › peer-review
Cellular effects of peptide and protein hydroperoxides
Rahmanto, A. S., Morgan, P. E., Hawkins, Clare Louise & Davies, Michael J., 15 Apr 2010, In: Free Radical Biology & Medicine. 48, 8, p. 1071-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Cellular effects of photogenerated oxidants and long-lived, reactive, hydroperoxide photoproducts
Rahmanto, A. S., Morgan, P. E., Hawkins, Clare Louise & Davies, Michael J., 30 Nov 2010, In: Free Radical Biology & Medicine. 49, 10, p. 1505-15 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Reactions and reactivity of myeloperoxidase-derived oxidants: differential biological effects of hypochlorous and hypothiocyanous acids
Pattison, D. I., Davies, Michael J. & Hawkins, Clare Louise, Aug 2012, In: Free Radical Research. 46, 8, p. 975-95 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
Hypochlorous acid-mediated protein oxidation: how important are chloramine transfer reactions and protein tertiary structure?
Pattison, D. I., Hawkins, Clare Louise & Davies, Michael J., 28 Aug 2007, In: Biochemistry. 46, 34, p. 9853-64 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
What are the plasma targets of the oxidant hypochlorous acid? A kinetic modeling approach
Pattison, D. I., Hawkins, Clare Louise & Davies, Michael J., May 2009, In: Chemical Research in Toxicology. 22, 5, p. 807-17 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypochlorous acid-mediated oxidation of lipid components and antioxidants present in low-density lipoproteins: absolute rate constants, product analysis, and computational modeling
Pattison, D. I., Hawkins, Clare Louise & Davies, Michael J., Apr 2003, In: Chemical Research in Toxicology. 16, 4, p. 439-49 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A pivotal role for NF-κB in the macrophage inflammatory response to the myeloperoxidase oxidant hypothiocyanous acid
Pan, G., Rayner, B., Zhang, Y., van Reyk, D. & Hawkins, Clare Louise, 2018, In: Archives of Biochemistry and Biophysics. 642, p. 23-30 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
New roles of neutrophils and granulocytic MDSC in autoimmune diseases, inflammation, and anti-microbial immunity
Odobasic, D., Hawkins, Clare Louise & Radic, M., 2022, In: Frontiers in Immunology. 13, 2 p., 974062.Research output: Contribution to journal › Editorial › Research › peer-review
High plasma thiocyanate levels in smokers are a key determinant of thiol oxidation induced by myeloperoxidase
Morgan, P. E., Pattison, D. I., Talib, J., Summers, F. A., Harmer, J. A., Celermajer, D. S., Hawkins, Clare Louise & Davies, Michael J., 1 Nov 2011, In: Free Radical Biology & Medicine. 51, 9, p. 1815-22 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Separation, detection, and quantification of hydroperoxides formed at side-chain and backbone sites on amino acids, peptides, and proteins
Morgan, P. E., Pattison, D. I., Hawkins, Clare Louise & Davies, Michael J., 1 Nov 2008, In: Free Radical Biology & Medicine. 45, 9, p. 1279-89 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Role for Chlorinated Nucleosides in the Perturbation of Macrophage Function and Promotion of Inflammation
Macer-Wright, J. L., Stanley, N. R., Portman, N., Tan, J. T., Bursill, C., Rayner, B. S. & Hawkins, Clare Louise, 2019, In: Chemical Research in Toxicology. 32, 6, p. 1223-1234Research output: Contribution to journal › Journal article › Research › peer-review
- Published
8-chloroadenosine alters the metabolic profile and downregulates antioxidant and DNA damage repair pathways in macrophages
Macer-Wright, J., Sileikaite, I., Rayner, B. & Hawkins, Clare Louise, 2020, In: Chemical Research in Toxicology. 33, 2, p. 402-413Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of the myeloperoxidase-derived oxidant hypothiocyanous acid (HOSCN) in the induction of mitochondrial dysfunction in macrophages
Love, D. T., Guo, C., Nikelshparg, E. I., Brazhe, N. A., Sosnovtseva, Olga & Hawkins, Clare Louise, 2020, In: Redox Biology. 36, 12 p., 101602.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cellular targets of the myeloperoxidase-derived oxidant hypothiocyanous acid (HOSCN) and its role in the inhibition of glycolysis in macrophages
Love, D., Barrett, T. J., White, M. Y., Cordwell, S. J., Davies, Michael J. & Hawkins, Clare Louise, 2016, In: Free Radical Biology & Medicine. 94, p. 88-98 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
A Nitric Oxide Storage and Transport System That Protects Activated Macrophages from Endogenous Nitric Oxide Cytotoxicity
Lok, H. C., Sahni, S., Jansson, P. J., Kovacevic, Z., Hawkins, Clare Louise & Richardson, D. R., 30 Dec 2016, In: The Journal of Biological Chemistry. 291, 53, p. 27042-27061 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
Nitric oxide storage and transport in cells are mediated by glutathione S-transferase P1-1 and multidrug resistance protein 1 via dinitrosyl iron complexes
Lok, H. C., Suryo Rahmanto, Y., Hawkins, Clare Louise, Kalinowski, D. S., Morrow, C. S., Townsend, A. J., Ponka, P. & Richardson, D. R., 2 Jan 2012, In: The Journal of Biological Chemistry. 287, 1, p. 607-18 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Comparative reactivity of the myeloperoxidase-derived oxidants hypochlorous acid and hypothiocyanous acid with human coronary artery endothelial cells
Lloyd, M. M., Grima, M. A., Rayner, B. S., Hadfield, K. A., Davies, Michael J. & Hawkins, Clare Louise, Dec 2013, In: Free Radical Biology & Medicine. 65, p. 1352-62 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Hypothiocyanous acid is a more potent inducer of apoptosis and protein thiol depletion in murine macrophage cells than hypochlorous acid or hypobromous acid
Lloyd, M. M., van Reyk, D. M., Davies, Michael J. & Hawkins, Clare Louise, 1 Sep 2008, In: Biochemical Journal. 414, 2, p. 271-80 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human Indoleamine 2,3-Dioxygenase 1 Is an Efficient Mammalian Nitrite Reductase
Lim, Y. J., Foo, T. C., Yeung, A. W. S., Tu, X., Ma, Y., Hawkins, Clare Louise, Witting, P. K., Jameson, G. N. L., Terentis, A. C. & Thomas, S. R., 2019, In: Biochemistry. 58, 7, p. 974-986Research output: Contribution to journal › Journal article › Research › peer-review
ID: 173742266
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Catalytic oxidant scavenging by selenium-containing compounds: Reduction of selenoxides and N-chloramines by thiols and redox enzymes
Research output: Contribution to journal › Journal article › Research › peer-review
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181
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Low-density lipoprotein modified by myeloperoxidase oxidants induces endothelial dysfunction
Research output: Contribution to journal › Journal article › Research › peer-review
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154
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Changes in mitochondrial homeostasis and redox status in astronauts following long stays in space
Research output: Contribution to journal › Journal article › Research › peer-review
Published