Clare Louise Hawkins

Clare Louise Hawkins

Professor MSO

ORCID: 0000-0003-2738-5089

Publication year:
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76 - 100 out of 110Page size: 25
  1. 2012

  2. Reactions and reactivity of myeloperoxidase-derived oxidants: differential biological effects of hypochlorous and hypothiocyanous acids

    Pattison, D. I., Davies, Michael J. & Hawkins, Clare Louise, Aug 2012, In: Free Radical Research. 46, 8, p. 975-95 21 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Identification of proteins susceptible to thiol oxidation in endothelial cells exposed to hypochlorous acid and N-chloramines

    Summers, F. A., Forsman Quigley, A. & Hawkins, Clare Louise, 24 Aug 2012, In: Biochemical and Biophysical Research Communications. 425, 2, p. 157-61 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. 2011

  5. Amino acid, peptide, and protein hydroperoxides and their decomposition products modify the activity of the 26S proteasome

    Gracanin, M., Lam, M. A., Morgan, P. E., Rodgers, K. J., Hawkins, Clare Louise & Davies, Michael J., 15 Jan 2011, In: Free Radical Biology & Medicine. 50, 2, p. 389-99 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. High plasma thiocyanate levels in smokers are a key determinant of thiol oxidation induced by myeloperoxidase

    Morgan, P. E., Pattison, D. I., Talib, J., Summers, F. A., Harmer, J. A., Celermajer, D. S., Hawkins, Clare Louise & Davies, Michael J., 1 Nov 2011, In: Free Radical Biology & Medicine. 51, 9, p. 1815-22 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. The potent and novel thiosemicarbazone chelators di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone and 2-benzoylpyridine-4,4-dimethyl-3-thiosemicarbazone affect crucial thiol systems required for ribonucleotide reductase activity

    Yu, Y., Suryo Rahmanto, Y., Hawkins, Clare Louise & Richardson, D. R., Jun 2011, In: Molecular Pharmacology. 79, 6, p. 921-31 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. 2010

  9. The iron complex of Dp44mT is redox-active and induces hydroxyl radical formation - an EPR study

    Jansson, P. J., Hawkins, Clare Louise, Lovejoy, D. B. & Richardson, D. R., Nov 2010, In: Journal of Inorganic Biochemistry. 104, 11, p. 1224-8 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Acetaminophen (paracetamol) inhibits myeloperoxidase-catalyzed oxidant production and biological damage at therapeutically achievable concentrations

    Koelsch, M., Mallak, R., Graham, G. G., Kajer, T., Milligan, M. K., Nguyen, L. Q., Newsham, D. W., Keh, J. S., Kettle, A. J., Scott, K. F., Ziegler, J. B., Pattison, D. I., Fu, S., Hawkins, Clare Louise, Rees, M. D. & Davies, Michael J., 15 Apr 2010, In: Biochemical Pharmacology. 79, 8, p. 1156-64 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. The myeloperoxidase-derived oxidant HOSCN inhibits protein tyrosine phosphatases and modulates cell signalling via the mitogen-activated protein kinase (MAPK) pathway in macrophages

    Lane, A. E., Tan, J. T. M., Hawkins, Clare Louise, Heather, A. K. & Davies, Michael J., 15 Aug 2010, In: Biochemical Journal. 430, 1, p. 161-9 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Cellular effects of peptide and protein hydroperoxides

    Rahmanto, A. S., Morgan, P. E., Hawkins, Clare Louise & Davies, Michael J., 15 Apr 2010, In: Free Radical Biology & Medicine. 48, 8, p. 1071-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Cellular effects of photogenerated oxidants and long-lived, reactive, hydroperoxide photoproducts

    Rahmanto, A. S., Morgan, P. E., Hawkins, Clare Louise & Davies, Michael J., 30 Nov 2010, In: Free Radical Biology & Medicine. 49, 10, p. 1505-15 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Ability of hypochlorous acid and N-chloramines to chlorinate DNA and its constituents

    Stanley, N. R., Pattison, D. I. & Hawkins, Clare Louise, 19 Jul 2010, In: Chemical Research in Toxicology. 23, 7, p. 1293-302 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. 2009

  16. Singlet-oxygen-mediated amino acid and protein oxidation: formation of tryptophan peroxides and decomposition products

    Gracanin, M., Hawkins, Clare Louise, Pattison, D. I. & Davies, Michael J., 1 Jul 2009, In: Free Radical Biology & Medicine. 47, 1, p. 92-102 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. The role of hypothiocyanous acid (HOSCN) in biological systems

    Hawkins, Clare Louise, Dec 2009, In: Free Radical Research. 43, 12, p. 1147-58 12 p.

    Research output: Contribution to journal › Journal article › Commissioned › peer-review

  18. Quantification of protein modification by oxidants

    Hawkins, Clare Louise, Morgan, P. E. & Davies, Michael J., 15 Apr 2009, In: Free Radical Biology & Medicine. 46, 8, p. 965-88 24 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. What are the plasma targets of the oxidant hypochlorous acid? A kinetic modeling approach

    Pattison, D. I., Hawkins, Clare Louise & Davies, Michael J., May 2009, In: Chemical Research in Toxicology. 22, 5, p. 807-17 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. 2008

  21. Mammalian heme peroxidases: from molecular mechanisms to health implications

    Davies, Michael J., Hawkins, Clare Louise, Pattison, D. I. & Rees, M. D., Jul 2008, In: Antioxidants & Redox Signaling. 10, 7, p. 1199-234 36 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Tryptophan residues are targets in hypothiocyanous acid-mediated protein oxidation

    Hawkins, Clare Louise, Pattison, D. I., Stanley, N. R. & Davies, Michael J., 15 Dec 2008, In: Biochemical Journal. 416, 3, p. 441-52 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Hypothiocyanous acid is a more potent inducer of apoptosis and protein thiol depletion in murine macrophage cells than hypochlorous acid or hypobromous acid

    Lloyd, M. M., van Reyk, D. M., Davies, Michael J. & Hawkins, Clare Louise, 1 Sep 2008, In: Biochemical Journal. 414, 2, p. 271-80 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Separation, detection, and quantification of hydroperoxides formed at side-chain and backbone sites on amino acids, peptides, and proteins

    Morgan, P. E., Pattison, D. I., Hawkins, Clare Louise & Davies, Michael J., 1 Nov 2008, In: Free Radical Biology & Medicine. 45, 9, p. 1279-89 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Identification of plasma proteins that are susceptible to thiol oxidation by hypochlorous acid and N-chloramines

    Summers, F. A., Morgan, P. E., Davies, Michael J. & Hawkins, Clare Louise, Sep 2008, In: Chemical Research in Toxicology. 21, 9, p. 1832-40 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Hypochlorous acid oxidizes methionine and tryptophan residues in myoglobin

    Szuchman-Sapir, A. J., Pattison, D. I., Ellis, N. A., Hawkins, Clare Louise, Davies, Michael J. & Witting, P. K., 15 Sep 2008, In: Free Radical Biology & Medicine. 45, 6, p. 789-98 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. 2007

  28. Hypochlorous acid-mediated protein oxidation: how important are chloramine transfer reactions and protein tertiary structure?

    Pattison, D. I., Hawkins, Clare Louise & Davies, Michael J., 28 Aug 2007, In: Biochemistry. 46, 34, p. 9853-64 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. 2006

  30. Sensitizer-mediated photooxidation of histidine residues: evidence for the formation of reactive side-chain peroxides

    Agon, V. V., Bubb, W. A., Wright, A., Hawkins, Clare Louise & Davies, Michael J., 15 Feb 2006, In: Free Radical Biology & Medicine. 40, 4, p. 698-710 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. 2005

  32. Inactivation of protease inhibitors and lysozyme by hypochlorous acid: role of side-chain oxidation and protein unfolding in loss of biological function

    Hawkins, Clare Louise & Davies, Michael J., Oct 2005, In: Chemical Research in Toxicology. 18, 10, p. 1600-10 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. The role of aromatic amino acid oxidation, protein unfolding, and aggregation in the hypobromous acid-induced inactivation of trypsin inhibitor and lysozyme

    Hawkins, Clare Louise & Davies, Michael J., Nov 2005, In: Chemical Research in Toxicology. 18, 11, p. 1669-77 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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