Christina Christoffersen

Christina Christoffersen

Associate Professor


  1. 2018
  2. Published

    Site-specific O-glycosylation of members of the low-density lipoprotein receptor superfamily enhances ligand interactions

    Wang, S., Mao, Y., Narimatsu, Y., Ye, Z., Tian, W., Goth, C. K., Lira-Navarrete, E., Pedersen, N. B., Benito-Vicente, A., Martin, C., Uribe, K. B., Hurtado-Guerrero, R., Christoffersen, C., Seidah, N. G., Nielsen, R., Christensen, E. I., Hansen, L., Bennett, E. P., Vakhrushev, S. Y., Schjoldager, K. T. & 1 others, Clausen, Henrik, 2018, In: The Journal of Biological Chemistry. 293, 19, p. 7408 –7422

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2017
  4. Published

    ApoB and apoM - New aspects of lipoprotein biology in uremia-induced atherosclerosis

    Christoffersen, Christina, Bartels, Emil Daniel, Pedersen, A. A., Nielsen, L. B. & Pedersen, T. X., Dec 2017, In: European Journal of Pharmacology. 816, p. 154-160 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Apolipoprotein M mediates sphingosine-1-phosphate efflux from erythrocytes

    Christensen, P. M., Bosteen, M. H., Hajny, Stefan, Nielsen, L. B. & Christoffersen, Christina, 8 Nov 2017, In: Scientific Reports. 7, 10 p., 14983.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Effects of apolipoprotein M in uremic atherosclerosis

    Bosteen, M. H., Madsen Svarrer, E. M., Bisgaard, Line, Martinussen, Torben, Madsen, M., Nielsen, L. B., Christoffersen, Christina & Pedersen, T. X., Oct 2017, In: Atherosclerosis. 265, p. 93-101 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    A Novel Perspective on the ApoM-S1P Axis, Highlighting the Metabolism of ApoM and Its Role in Liver Fibrosis and Neuroinflammation

    Hajny, Stefan & Christoffersen, Christina, 27 Jul 2017, In: International Journal of Molecular Sciences. 18, 8, 19 p., 1636.

    Research output: Contribution to journalReviewResearchpeer-review

  8. Published

    High density lipoprotein (HDL)-associated sphingosine 1-phosphate (S1P) inhibits macrophage apoptosis by stimulating STAT3 activity and survivin expression

    Feuerborn, R., Becker, S., Potì, F., Nagel, P., Brodde, M., Schmidt, H., Christoffersen, Christina, Ceglarek, U., Burkhardt, R. & Nofer, J., Feb 2017, In: Atherosclerosis. 257, p. 29-37 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Apolipoprotein E Deficiency Increases Remnant Lipoproteins and Accelerates Progressive Atherosclerosis, But Not Xanthoma Formation, in Gene-Modified Minipigs

    Shim, J., Poulsen, C. B., Hagensen, M. K., Larsen, T., Heegaard, P. M. H., Christoffersen, Christina, Bolund, L., Schmidt, M., Liu, Y., Li, J., Li, R., Callesen, H., Bentzon, J. F. & Sørensen, C. B., 2017, In: JACC: Basic to Translational Science. 2, 5, p. 591-600 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2016
  11. Published

    HDL activation of endothelial sphingosine-1-phosphate receptor-1 (S1P1) promotes regeneration and suppresses fibrosis in the liver

    Ding, B., Liu, C. H., Sun, Y., Chen, Y., Swendeman, S. L., Jung, B., Chavez, D., Cao, Z., Christoffersen, Christina, Nielsen, L. B., Schwab, S. R., Rafii, S. & Hla, T., 22 Dec 2016, In: JCI insight. 1, 21, 16 p., e87058.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Hypoxia-Inducible Factor-1α Expression in Macrophages Promotes Development of Atherosclerosis

    Pedersen, A. A., Pedersen, T. X., Junker, N., Christoffersen, Christina, Bartels, Emil Daniel, Madsen, M., Nielsen, Carsten Haagen & Nielsen, L. B., Sep 2016, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 36, 9, p. 1782-1790 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Loss of Function of GALNT2 Lowers High-Density Lipoproteins in Humans, Nonhuman Primates, and Rodents

    Khetarpal, S. A., Schjoldager, K. T., Christoffersen, C., Raghavan, A., Edmondson, A. C., Reutter, H. M., Ahmed, B., Ouazzani, R., Peloso, G. M., Vitali, C., Zhao, W., Somasundara, A. V. H., Millar, J. S., Park, Y., Fernando, G., Livanov, V., Choi, S., Noé, E., Patel, P., Ho, S. P. & 12 others, Kirchgessner, T. G., Wandall, Hans H., Hansen, Lars, Bennett, Eric Paul, Vakhrushev, Sergey, Saleheen, D., Kathiresan, S., Brown, C. D., Abou Jamra, R., LeGuern, E., Clausen, Henrik & Rader, D. J., 9 Aug 2016, In: Cell Metabolism. 24, 2, p. 234-245 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Familial hypercholesterolaemia: cholesterol efflux and coronary disease

    Versmissen, J., Vongpromek, R., Yahya, R., van der Net, J. B., van Vark-van der Zee, L., Blommesteijn-Touw, J., Wattimena, D., Rietveld, T., Pullinger, C. R., Christoffersen, Christina, Dahlbäck, B., Kane, J. P., Mulder, M. & Sijbrands, E. J. G., Jul 2016, In: European Journal of Clinical Investigation. 46, 7, p. 643-50 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Impaired endothelial barrier function in apolipoprotein M-deficient mice is dependent on sphingosine-1-phosphate receptor 1

    Christensen, P. M., Liu, C. H., Swendeman, S. L., Obinata, H., Qvortrup, Klaus, Nielsen, L. B., Hla, T., Di Lorenzo, A. & Christoffersen, Christina, Jun 2016, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 30, 6, p. 2351-2359 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Sphingosine-1-Phosphate reduces ischemia/reperfusion injury by phosphorylating the gap junction protein Connexin43

    Morel, S., Christoffersen, Christina, Axelsen, L. N., Montecucco, F., Rochemont, V., Frias, M. A., Mach, F., James, R. W., Naus, C. C., Chanson, M., Lampe, P. D., Nielsen, Morten Schak, Nielsen, L. B. & Kwak, B. R., 13 Jan 2016, In: Cardiovascular Research. 109, p. 385-396 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. 2015
  18. Published

    Diurnal gene expression of lipolytic natriuretic peptide receptors in white adipose tissue

    Smith, J., Fahrenkrug, J., Jørgensen, H. L., Christoffersen, Christina & Goetze, J. P., Dec 2015, In: Endocrine Connections. 4, 4, p. 206-214 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Protein unfolding allows use of commercial antibodies in an apolipoprotein M sandwich ELISA

    Bosteen, M. H., Dahlbäck, B., Nielsen, L. B. & Christoffersen, Christina, 1 Mar 2015, In: Journal of Lipid Research. 56, 3, p. 754-759 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Apolipoprotein M in lipid metabolism and cardiometabolic diseases

    Borup, A., Christensen, P. M., Nielsen, L. B. & Christoffersen, Christina, Feb 2015, In: Current Opinion in Lipidology. 26, 1, p. 48-55 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  21. Published

    Altered Metabolism of LDL in the Arterial Wall Precedes Atherosclerosis Regression

    Bartels, Emil Daniel, Christoffersen, Christina, Lindholm, M. W. & Nielsen, L. B., 2015, In: Circulation Research. 117, p. 933-942 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Diabetes with poor glycaemic control does not promote atherosclerosis in genetically modified hypercholesterolaemic minipigs

    Al-Mashhadi, R. H., Bjørklund, M. M., Mortensen, M. B., Christoffersen, Christina, Larsen, T., Falk, E. & Bentzon, J. F., 2015, In: Diabetologia. 58, 8, p. 1926-36 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. 2014
  24. Published

    Induction of atherosclerosis in mice and hamsters without germline genetic engineering

    Bjørklund, M. M., Hollensen, A. K., Hagensen, M. K., Dagnæs-Hansen, F., Christoffersen, Christina, Mikkelsen, J. G. & Bentzon, J. F., 23 May 2014, In: Circulation Research. 114, 11, p. 1684-9 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Apolipoprotein M: Impact on lipoprotein metabolism and vascular function

    Christoffersen, Christina, 2014, Frederiksberg: Det Sundhedsvidenskabelige Fakultet, Københavns Universitet. 118 p.

    Research output: Book/ReportDoctoral thesisResearch

  26. Published

    Effect of atrial natriuretic peptide on lipolysis in the mouse heart

    Bartels, Emil Daniel, Bisgaard, Line, Christoffersen, Christina & Nielsen, L. B., 2014, In: Cardiovascular Endocrinology. 3, 3, p. 92-7 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. 2013
  28. Published

    Apolipoprotein M: bridging HDL and endothelial function

    Christoffersen, Christina & Nielsen, L. B., Aug 2013, In: Current Opinion in Lipidology. 24, 4, p. 295-300 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Apolipoprotein M promotes mobilization of cellular cholesterol in vivo

    Elsøe, S., Christoffersen, Christina, Luchoomun, J., Turner, S. & Nielsen, L. B., Jul 2013, In: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1831, 7, p. 1287-92 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Osteopontin deficiency dampens the pro-atherogenic effect of uraemia

    Pedersen, T. X., Madsen, M., Nielsen, N. M. J., Christoffersen, Christina, Vikeså, J., Bro, S., Hultgårdh-Nilsson, A. & Nielsen, L. B., 1 Jun 2013, In: Cardiovascular Research. 98, 3, p. 352-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    The apolipoprotein m-sphingosine-1-phosphate axis: biological relevance in lipoprotein metabolism, lipid disorders and atherosclerosis

    Arkensteijn, B. W. C., Berbée, J. F. P., Rensen, P. C. N., Nielsen, L. B. & Christoffersen, Christina, 25 Feb 2013, In: International Journal of Molecular Sciences (Online). 14, 3, p. 4419-31 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 18392597