Alicia Lundby

Alicia Lundby

Professor with special responsibilities, Affiliate Associate Professor


  1. 2022
  2. Published

    Beta-blocker/ACE inhibitor therapy differentially impacts the steady state signaling landscape of failing and non-failing hearts

    Sorrentino, Andrea, Bagwan, Navratan, Linscheid, N., Poulsen, P. C., Kahnert, Konstantin, Thomsen, Morten Bækgaard, Delmar, M. & Lundby, Alicia, Dec 2022, In: Scientific Reports. 12, 1, 13 p., 4760.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Exercise Causes Arrhythmogenic Remodeling of Intracellular Calcium Dynamics in Plakophilin-2-Deficient Hearts

    Van Opbergen, C. J. M., Bagwan, Navratan, Maurya, S. R., Kim, J. C., Smith, A. N., Blackwell, D. J., Johnston, J. N., Knollmann, B. C., Cerrone, M., Lundby, Alicia & Delmar, M., 2022, In: Circulation. 145, 19, p. 1480-1496

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Genome-wide association study reveals novel genetic loci: a new polygenic risk score for mitral valve prolapse

    Roselli, C., Yu, M., Nauffal, V., Georges, A., Yang, Q., Love, K., Weng, L., Delling, F. N., Maurya, S. R., Schrölkamp, Maren, Tfelt-Hansen, Jacob, Hagège, A., Jeunemaitre, X., Debette, S., Amouyel, P., Guan, W., Muehlschlegel, J. D., Body, S. C., Shah, S., Samad, Z., Kyryachenko, S., Haynes, C., Rienstra, M., Le Tourneau, T., Probst, V., Roussel, R., Wijdh-Den Hamer, I. J., Siland, J. E., Knowlton, K. U., Jacques Schott, J., Levine, R. A., Benjamin, E. J., Vasan, R. S., Horne, B. D., Muhlestein, J. B., Benfari, G., Enriquez-Sarano, M., Natale, A., Mohanty, S., Trivedi, C., Shoemaker, M. B., Yoneda, Z. T., Wells, Q. S., Baker, M. T., Farber-Eger, E., Michelena, H. I., Lundby, Alicia, Norris, R. A., Slaugenhaupt, S. A., Dina, C., Lubitz, S. A., Bouatia-Naji, N., Ellinor, P. T. & Milan, D. J., 2022, In: European Heart Journal. 43, 17, p. 1668–1680

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2021
  6. Published

    Beta-blocker/ACE inhibitor therapy differentially impacts the steady state signaling landscape of failing and non-failing hearts

    Sorrentino, Andrea, Bagwan, Navratan, Linscheid, N., Poulsen, P., Kahnert, Konstantin, Thomsen, Morten Bækgaard, Delmar, M. & Lundby, Alicia, 2021, In: European Heart Journal. 42, Suppl. 1, p. 3294-3294 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

  7. Published

    Oncotherapeutic Protein Kinase Inhibitors Associated With Pro-Arrhythmic Liability

    Ye, J. Z., Hansen, F. B., Mills, Robert William & Lundby, Alicia, 2021, In: JACC: CardioOncology. 3, 1, p. 88-97

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Proteome-wide profiling and mapping of post translational modifications in human hearts

    Bagwan, Navratan, El Ali, Henrik H. & Lundby, Alicia, 2021, In: Scientific Reports. 11, 1, 10 p., 2184.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Quantitative proteome comparison of human hearts with those of model organisms

    Linscheid, N., Santos Delgado, Alberto, Poulsen, P. C., Mills, Robert William, Callø, Kirstine, Leurs, U., Ye, J. Z., Stolte, C., Thomsen, Morten Bækgaard, Bentzen, Bo Hjorth, Lundegaard, Pia Rengtved, Olesen, Morten Steen Salling, Jensen, Lars Juhl, Olsen, Jesper Velgaard & Lundby, Alicia, 2021, In: PLOS Biology. 19, 4, 22 p., e3001144.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Spatial-proteomics reveals phospho-signaling dynamics at subcellular resolution

    Martinez Del Val, Ana, Bekker-Jensen, D. B., Steigerwald, S., Koenig, Claire, Østergaard, Ole, Mehta, A., Tran, T., Sikorski, K., Torres Vega, Estefania, Kwasniewicz, Ewa, Brynjólfsdóttir, S. H., Frankel, Lisa, Kjøbsted, Rasmus, Krogh, Nicolai, Lundby, Alicia, Bekker-Jensen, Simon Holst, Lund-Johansen, F. & Olsen, Jesper Velgaard, 2021, In: Nature Communications. 12, 1, 17 p., 7113.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2020
  12. Published

    Ibrutinib-Mediated Atrial Fibrillation Attributable to Inhibition of C-Terminal Src Kinase

    Xiao, L., Salem, J., Clauss, S., Hanley, A., Bapat, A., Hulsmans, M., Iwamoto, Y., Wojtkiewicz, G., Cetinbas, M., Schloss, M. J., Tedeschi, J., Lebrun-Vignes, B., Lundby, Alicia, Sadreyev, R., Moslehi, J., Nahrendorf, M., Ellinor, P. T. & Milan, D. J., 2020, In: Circulation. 142, 25, p. 2443-2455 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Molecular switches in signaling networks as a mechanism of action for oncogenic mutations in proximity of tyrosine residues

    Emdal, Kristina Bennet & Lundby, Alicia, 2020, In: Molecular & Cellular Oncology. 7, 1, 3 p., e1692643.

    Research output: Contribution to journalComment/debateResearchpeer-review

  14. Published

    Quantitative proteomics characterization of acutely isolated primary adult rat cardiomyocytes and fibroblasts

    Poulsen, P. C., Schrölkamp, Maren, Bagwan, Navratan, Leurs, U., Humphries, E. S. A., Bomholzt, S. H., Nielsen, Morten Schak, Bentzen, Bo Hjorth, Olsen, Jesper Velgaard & Lundby, Alicia, 2020, In: Journal of Molecular and Cellular Cardiology. 143, p. 63-70 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Quantitative proteomics of human heart samples collected In vivo reveal the remodeled protein landscape of dilated left atrium without atrial fibrillation

    Linscheid, N., Poulsen, P. C., Pedersen, I. D., Gregers, E., Svendsen, Jesper Hastrup, Olesen, Morten Steen Salling, Olsen, Jesper Velgaard, Delmar, M. & Lundby, Alicia, 2020, In: Molecular and Cellular Proteomics. 19, 7, p. 1132-1144

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. 2019
  17. Published

    Disruption of Ca2+i Homeostasis and Connexin 43 Hemichannel Function in the Right Ventricle Precedes Overt Arrhythmogenic Cardiomyopathy in Plakophilin-2-Deficient Mice

    Kim, J., Perez-Hernandez, M., Alvarado, F. J., Maurya, S. R., Montnach, J., Yin, Y., Zhang, M., Lin, X., Vasquez, C., Heguy, A., Liang, F., Woo, S., Morley, G. E., Rothenberg, E., Lundby, Alicia, Valdivia, H. H., Cerrone, M. & Delmar, M., 2019, In: Circulation. 140, 12, p. 1015-1030

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites

    Lundby, Alicia, Franciosa, Giulia, Emdal, Kristina Bennet, Refsgaard, J. C., Gnosa, Sebastian Peter, Bekker-Jensen, D. B., Secher, A., Maurya, S. R., Paul, I., Mendez, B. L., Kelstrup, C. D., Francavilla, C., Kveiborg, Marie, Montoya, Guillermo, Jensen, Lars Juhl & Olsen, Jesper Velgaard, 2019, In: Cell. 179, 2, p. 543-560

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Quantitative proteomics and single-nucleus transcriptomics of the sinus node elucidates the foundation of cardiac pacemaking

    Linscheid, N., Logantha, S. J. R. J., Poulsen, C., Zhang, S., Schrölkamp, Maren, Egerod, Kristoffer Lihme, Thompson, J. J., Kitmitto, A., Galli, G., Humphries, M. J., Zhang, H., Pers, Tune H, Olsen, Jesper Velgaard, Boyett, M. & Lundby, Alicia, 2019, In: Nature Communications. 10, 19 p., 2889.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Reevaluation of genetic variants previously associated with arrhythmogenic right ventricular cardiomyopathy integrating population-based cohorts and proteomics data

    Ye, J. Z., Delmar, M., Lundby, Alicia & Olesen, Morten Steen Salling, 2019, In: Clinical Genetics. 96, 6, p. 506-514

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. 2018
  22. Published

    Integrated proximal proteomics reveals IRS2 as a determinant of cell survival in ALK-driven neuroblastoma

    Emdal, Kristina Bennet, Pedersen, Anna-Kathrine, Bekker-Jensen, D. B., Lundby, Alicia, Claeys, S., De Preter, K., Speleman, F., Francavilla, C. & Olsen, Jesper Velgaard, 20 Nov 2018, In: Science Signaling. 11, 557, p. 1-17 17 p., eaap9752.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Control of endothelial cell tube formation by Notch ligand intracellular domain interactions with activator protein 1 (AP-1)

    Forghany, Z., Robertson, F., Lundby, Alicia, Olsen, Jesper Velgaard & Baker, D. A., 2018, In: Journal of Biological Chemistry. 293, 4, p. 1229-1242 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    PKD Phosphorylation as Novel Pathway of KV11.1 Regulation

    Steffensen, Annette Buur, Bomholtz, Sofia Hammami, Andersen, M. N., Olsen, Jesper Velgaard, Mutsaers, N., Lundegaard, Pia Rengtved, Lundby, Alicia & Schmitt, Nicole, 2018, In: Cellular Physiology and Biochemistry. 47, 4, p. 1742-1750 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Rare truncating variants in the sarcomeric protein titin associate with familial and early-onset atrial fibrillation

    Ahlberg, G., Refsgaard, L., Lundegaard, Pia Rengtved, Andreasen, Laura Korsholm, Ranthe, M. F., Linscheid, N., Nielsen, J. B., Melbye, Mads, Haunsø, Stig, Sajadieh, Ahmad, Camp, L., Olesen, Søren-Peter, Rasmussen, Simon, Lundby, Alicia, Ellinor, P. T., Holst, A. G., Svendsen, Jesper Hastrup & Olesen, Morten Steen Salling, 2018, In: Nature Communications. 9, 1, 11 p., 4316.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. 2017
  27. Published

    Targeting miR-423-5p Reverses Exercise Training-Induced HCN4 Channel Remodeling and Sinus Bradycardia

    D'Souza, A., Pearman, C. M., Wang, Y., Nakao, S., Logantha, S. J. R. J., Cox, C., Bennett, H., Zhang, Y., Johnsen, A. B., Linscheid, N., Poulsen, P. C., Elliott, J., Coulson, J., McPhee, J., Robertson, A., Da Costa Martins, P. A., Kitmitto, A., Wisløff, U., Cartwright, E. J., Monfredi, O., Lundby, Alicia, Dobrzynski, H., Oceandy, D., Morris, G. M. & Boyett, M. R., Oct 2017, In: Circulation Research. 121, 9, p. 1058-1068 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    KIT(D816V) Induces SRC-Mediated Tyrosine Phosphorylation of MITF and Altered Transcription Program in Melanoma

    Phung, B., Kazi, J. U., Lundby, Alicia, Bergsteinsdottir, K., Sun, J., Goding, C. R., Jönsson, G., Olsen, Jesper Velgaard, Steingrímsson, E. & Rönnstrand, L., 2017, In: Molecular cancer research : MCR. 15, 9, p. 1265-1274 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. 2016
  30. Published

    52 Genetic Loci Influencing Myocardial Mass

    van der Harst, P., van Setten, J., Verweij, N., Vogler, G., Franke, L., Maurano, M. T., Wang, X., Mateo Leach, I., Eijgelsheim, M., Sotoodehnia, N., Hayward, C., Sorice, R., Meirelles, O., Lyytikäinen, L., Polašek, O., Tanaka, T., Arking, D. E., Ulivi, S., Trompet, S., Müller-Nurasyid, M., Smith, A. V., Dörr, M., Kerr, K. F., Magnani, J. W., Del Greco M, F., Zhang, W., Nolte, I. M., Silva, C. T., Padmanabhan, S., Tragante, V., Esko, T., Abecasis, G. R., Adriaens, M. E., Andersen, K., Barnett, P., Bis, J. C., Bodmer, R., Buckley, B. M., Campbell, H., Cannon, M. V., Chakravarti, A., Chen, L. Y., Delitala, A., Devereux, R. B., Doevendans, P. A., Dominiczak, A. F., Ferrucci, L., Ford, I., Gieger, C., Harris, T. B., Haugen, E., Heinig, M., Hernandez, D. G., Hillege, H. L., Hirschhorn, J. N., Hofman, A., Hubner, N., Hwang, S., Iorio, A., Kähönen, M., Kellis, M., Kolcic, I., Kooner, I. K., Kooner, J. S., Kors, J. A., Lakatta, E. G., Lage, K., Launer, L. J., Levy, D., Lundby, Alicia, Macfarlane, P. W., May, D., Meitinger, T., Metspalu, A., Nappo, S., Naitza, S., Neph, S., Nord, A. S., Nutile, T., Okin, P. M., Olsen, Jesper Velgaard, Oostra, B. A., Penninger, J. M., Pennacchio, L. A., Pers, Tune H, Perz, S., Peters, A., Pinto, Y. M., Pfeufer, A., Pilia, M. G., Pramstaller, P. P., Prins, B. P., Raitakari, O. T., Raychaudhuri, S., Rice, K. M., Rossin, E. J., Rotter, J. I., Schafer, S., Schlessinger, D., Schmidt, C. O., Sehmi, J., Silljé, H. H. W., Sinagra, G., Sinner, M. F., Slowikowski, K., Soliman, E. Z., Spector, T. D., Spiering, W., Stamatoyannopoulos, J. A., Stolk, R. P., Strauch, K., Tan, S., Tarasov, K. V., Trinh, B., Uitterlinden, A. G., van den Boogaard, M., van Duijn, C. M., van Gilst, W. H., Viikari, J. S., Visscher, P. M., Vitart, V., Völker, U., Waldenberger, M., Weichenberger, C. X., Westra, H., Wijmenga, C., Wolffenbuttel, B. H., Yang, J., Bezzina, C. R., Munroe, P. B., Snieder, H., Wright, A. F., Rudan, I., Boyer, L. A., Asselbergs, F. W., van Veldhuisen, D. J., Stricker, B. H., Psaty, B. M., Ciullo, M., Sanna, S., Lehtimäki, T., Wilson, J. F., Bandinelli, S., Alonso, A., Gasparini, P., Jukema, J. W., Kääb, S., Gudnason, V., Felix, S. B., Heckbert, S. R., de Boer, R. A., Newton-Cheh, C., Hicks, A. A., Chambers, J. C., Jamshidi, Y., Visel, A., Christoffels, V. M., Isaacs, A., Samani, N. J. & de Bakker, P. I. W., 27 Sep 2016, In: Journal of the American College of Cardiology. 68, 13, p. 1435-48 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. 2015
  32. Published

    Protein kinase A stimulates Kv7.1 surface expression by regulating Nedd4-2-dependent endocytic trafficking

    Andersen, M. N., Hefting, L. L., Steffensen, Annette Buur, Schmitt, Nicole, Olesen, Søren-Peter, Olsen, Jesper Velgaard, Lundby, Alicia & Rasmussen, Hanne Borger, 15 Nov 2015, In: American Journal of Physiology: Cell Physiology. 309, 10, p. C693-C706 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Flere kvinder giver fair play

    Lundby, Alicia, Gerken, M., Quist, Pia, Bille, M. & Dahl, Tais Wittchen, 29 May 2015, In: Weekendavisen.

    Research output: Contribution to journalContribution to newspaper - Feature articleCommunication

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