Jens Juul Holst

Jens Juul Holst

Professor


  1. 2007
  2. Published

    Acute effects of ghrelin administration on glucose and lipid metabolism.

    Vestergaard, E. T., Djurhuus, C. B., Gjedsted, J., Nielsen, S., Møller, N., Holst, Jens Juul, Jørgensen, J. O. L. & Schmitz, O., 2007, In: Journal of Clinical Endocrinology and Metabolism. 93, 2, p. 438-444 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Bone resorption is decreased postprandially by intestinal factors and glucagon-like peptide-2 is a possible candidate

    Holst, Jens Juul, Hartmann, B., Gottschalck, I. B., Jeppesen, P. B., Miholic, J. & Henriksen, D. B., 2007, In: Scandinavian Journal of Gastroenterology. 42, 7, p. 814-820 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Cecal infusion of butyrate increases intestinal cell proliferation in piglets

    Kien, C. L., Blauwiekel, R., Bunn, J. Y., Jetton, T. L., Frankel, W. L. & Holst, Jens Juul, 2007, In: Journal of Nutrition. 137, 4, p. 916-922 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Co-localisation of the Kir6.2/SUR1 channel complex with glucagon-like peptide-1 and glucose-dependent insulinotrophic polypeptide expression in human ileal cells and implications for glycaemic control in new onset type 1 diabetes

    Nielsen, L. B., Ploug, K. B., Swift, P., Ørskov, A. C., Jansen-Olesen, I., Chiarelli, F., Holst, J. J., Hougaard, P. P., Porksen, S., Holl, R., Beaufort, C. D., Gammeltoft, S., Rorsman, P., Mortensen, H. B., Hansen, L., Nielsen, L. B., Ploug, K. B., Swift, P., Ørskov, C., Jansen-Olesen, I. & 11 others, Chiarelli, F., Holst, J. J., Hougaard, P., Pörksen, S., Holl, R., de Beaufort, C., Gammeltoft, S., Rorsman, P., Mortensen, H. B., Hansen, L. & Hvidøre Study Group, H. S. G., 2007, In: European Journal of Endocrinology. 156, 6, p. 663-71 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Disassociation of bone resorption and formation by GLP-2 - A 14-day study in healthy postmenopausal women

    Henriksen, D. B., Alexandersen, P., Hartmann, B., Adrian, C. L., Byrjalsen, I., Bone, H. G., Holst, Jens Juul & Christiansen, C., 2007, In: Bone. 40, 3, p. 723-729 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Effect of dairy calcium or supplementary calcium on postprandial fat metabolism, appetite, and subsequent energy intake

    Lorenzen, J. K., Nielsen, S., Holst, Jens Juul, Tetens, Inge , Rehfeld, Jens Frederik & Astrup, A., 2007, In: American Journal of Clinical Nutrition. 85, 3, p. 678-687 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Effect of subcutaneous injections of PYY1-36 and PYY3-36 on appetite, ad libitum energy intake, and plasma free fatty acids concentration in obese males

    Sloth, B., Davidsen, L., Holst, Jens Juul, Flint, A. & Astrup, A., 2007, In: American Journal of Physiology: Endocrinology and Metabolism. 293, 2, p. E604-E609

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Enteric neural pathways mediate the anti-inflammatory actions of glucagon-like peptide 2

    Sigalet, D. L., Wallace, L. E., Holst, Jens Juul, Martin, G. R., Kaji, T., Tanaka, H. & Sharkey, K. A., 2007, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 293, 1, p. G211-G221

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Exaggerated glucagon-like peptide-1 and blunted glucose-dependent insulinotropic peptide secretion are associated with Roux-en-Y gastric bypass but not adjustable gastric banding.

    Korner, J., Bessler, M., Inabnet, W., Taveras, C. & Holst, Jens Juul, 2007, In: Surgery for Obesity and Related Diseases. 3, 6, p. 597-601 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Exendin-4, but not dipeptidyl peptidase IV inhibition, increases small intestinal mass in GK rats.

    Simonsen, L., Pilgaard, S., Orskov, C., Rosenkilde, Mette, Hartmann, B., Holst, Jens Juul & Deacon, Carolyn F., 2007, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 293, 1, p. G288-95

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    GIP receptor antagonism reverses obesity, insulin resistance, and associated metabolic disturbances induced in mice by prolonged consumption of high-fat diet

    McClean, P. L., Irwin, N., Cassidy, R. S., Holst, Jens Juul, Gault, V. A. & Flatt, P. R., 2007, In: American Journal of Physiology: Endocrinology and Metabolism. 293, 6, p. E1746-E1755

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    GLUT2 and the incretin receptors are involved in glucose-induced incretin secretion

    Cani, P. D., Holst, Jens Juul, Drucker, D. J., Delzenne, N. M., Thorens, B., Burcelin, R. & Knauf, C., 2007, In: Molecular and Cellular Endocrinology. 276, 1-2, p. 18-23 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Gastric emptying of glucose solution and associated plasma concentrations of GLP-1, GIP, and PYY before and after fundoplication

    Miholic, J., Hoffmann, M., Holst, Jens Juul, Lenglinger, J., Mittlbock, M., Bergmann, H. & Stacher, G., 2007, In: Surgical Endoscopy and Other Interventional Techniques. 21, 2, p. 309-314 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Gastrointestinal function and metabolic control after construction of an orthotopic ileal neobladder in bladder cancer.

    Thorstenson, A., Jacobsson, H., Onelöv, E., Holst, Jens Juul, Hellström, P. M. & Kinn, A., 2007, In: Scandinavian Journal of Urology and Nephrology. 41, 1, p. 14-9 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Glucagon-like peptide 1 (GLP-1) suppresses ghrelin levels in humans via increased insulin secretion

    Hagemann, D., Holst, Jens Juul, Gethmann, A., Banasch, M., Schmidt, W. E. & Meier, J. J., 2007, In: Regulatory Peptides. 143, 1-3, p. 64-68 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Glucagon-like peptide 2 has limited efficacy to increase nutrient absorption in fetal and preterm pigs

    Sangild, Per Torp, Malo, C., Schmidt, M., Petersen, Y. M., Elnif, J., Holst, Jens Juul & Bunddington, R. K., 2007, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 293, 6, p. R2179-R2184 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Glucagon-like peptide-2 in umbilical cord blood from mature infants

    Bodé, S., Hartmann, Bolette, Holst, Jens Juul & Greisen, Gorm, 2007, In: Neonatology. 91, 1, p. 49-53 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Glucagon-like peptide-2 in umbilical cord blood from mature infants

    Bode, S., Hartmann, B., Holst, Jens Juul & Greisen, Gorm, 2007, In: Neonatology. 91, 1, p. 49-53 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Hepatic autoregulation: response of glucose production and gluconeogenesis to increased glycogenolysis

    Stæhr, P. A., Hother-Nielsen, O., Beck-Nielsen, H., Roden, M., Stingl, H., Holst, Jens Juul, Jones, P. K., Chandramouli, V. & Landau, B. R., 2007, In: American Journal of Physiology: Endocrinology and Metabolism. 292, 5, p. E1265-E1269

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Impaired glucagon-like peptide-1-induced insulin secretion in carriers of transcription factor 7-like 2 (TCF7L2) gene polymorphisms

    Schafer, S. A., Tschritter, O., Machicao, F., Thamer, C., Stefan, N., Gallwitz, B., Holst, Jens Juul, Dekker, J. M., t'Hart, L. M., Nijpels, G., Haeften, T. W. V., Haring, H. U. & Fritsche, A., 2007, In: Diabetologia. 50, 12, p. 2443-2450 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Meal-stimulated glucagon release is associated with postprandial blood glucose level and does not interfere with glycemic control in children and adolescents with new-onset type 1 diabetes

    Porksen, S., Nielsen, L. B., Kaas, A., Kocova, M., Chiarelli, F., Orskov, C., Holst, Jens Juul, Ploug, K. B., Hougaard, P. P., Hansen, L. & Mortensen, H. B., 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 8, p. 2910-2916 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Measurements of islet function and glucose metabolism with the dipeptidyl peptidase 4 inhibitor vildagliptin in patients with type 2 diabetes

    Azuma, K., Rádiková, Z., Mancino, J., Toledo, F. G. S., Thomas, E., Kangani, C., Dalla Man, C., Cobelli, C., Holst, Jens Juul, Deacon, Carolyn F., He, Y., Ligueros-Saylan, M., Serra, D., Foley, J. E. & Kelley, D. E., 2007, In: Journal of Clinical Endocrinology and Metabolism. 93, 2, p. 459-464 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Metabolic effects of amino acid mixtures and whey protein in healthy subjects: studies using glucose-equivalent drinks

    Nilsson, M., Holst, Jens Juul & Bjorck, I. M. E., 2007, In: American Journal of Clinical Nutrition. 85, 4, p. 996-1004 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    New horizons in diabetes therapy

    Holst, Jens Juul & Deacon, Carolyn F., 2007, In: Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry. 7, 1, p. 49-55 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Normal secretion of the incretin hormones glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 during gestational diabetes mellitus

    Cypryk, K., Vilsbøll, Tina, Nadel, I., Smyczynska, J., Holst, Jens Juul & Lewinski, A., 2007, In: Gynecological Endocrinology. 23, 1, p. 58-62 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Patients with neuroglycopenia after gastric bypass surgery have exaggerated incretin and insulin secretory responses to a mixed meal

    Goldfine, A. B., Mun, E. C., Devine, E., Bernier, R., Baz-Hecht, M., Jones, D. B., Schneider, B. E., Holst, Jens Juul & Patti, M. E., 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 12, p. 4678-4685 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Pharmacodynamics of vildagliptin in patients with type 2 diabetes during OGTT.

    He, Y., Wang, Y., Bullock, J. M., Deacon, Carolyn F., Holst, Jens Juul, Dunning, B. E., Ligueros-Saylan, M. & Foley, J. E., 2007, In: Journal of Clinical Pharmacology. 47, 5, p. 633-41 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Pharmacokinetics and pharmacodynamics of vildagliptin in patients with type 2 diabetes mellitus.

    He, Y., Serra, D., Wang, Y., Campestrini, J., Riviere, G., Deacon, Carolyn F., Holst, Jens Juul, Schwartz, S., Nielsen, J. C. & Ligueros-Saylan, M., 2007, In: Clinical Pharmacokinetics. 46, 7, p. 577-88 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Porcine glucagon-like peptide-2: structure, signaling, metabolism and effects

    Pedersen, N. B., Hjøllund, K. R., Johnsen, A. H., Ørskov, Cathrine, Rosenkilde, Mette, Hartmann, B. & Holst, Jens Juul, 2007, In: Regulatory Peptides. 146, 1-3, p. 310-320 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Preserved GLP-1 effects in a diabetic patient with Cushing's disease

    Ritzel, R. A., Kleine, N., Holst, Jens Juul, Willms, B., Schmiegel, W. & Nauck, M. A., 2007, In: Experimental and Clinical Endocrinology and Diabetes. 115, 2, p. 146-150 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Reduced incretin effect in type 2 diabetes: cause or consequence of the diabetic state?

    Knop, F. K., Vilsbøll, Tina, Højberg, P. V., Larsen, S., Madsbad, Sten, Vølund, A., Holst, Jens Juul & Krarup, T., 2007, In: Diabetes. 56, 8, p. 1951-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Reduction of hepatic insulin clearance after oral glucose ingestion is not mediated by glucagon-like peptide 1 or gastric inhibitory polypeptide in humans

    Meier, J. J., Holst, Jens Juul, Schmidt, W. E. & Nauck, M. A., 2007, In: American Journal of Physiology: Endocrinology and Metabolism. 293, 3, p. E849-E856

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Small molecule ago-allosteric modulators of the human glucagon-like peptide-1 (hGLP-1) receptor

    Teng, M., Johnson, M. D., Thomas, C., Kiel, D., Lakis, J. N., Kercher, T., Aytes, S., Kostrowicki, J., Bhumralkar, D., Truesdale, L., May, J., Sidelman, U., Kodra, J. T., Jørgensen, A. S., Olesen, P. H., Jong, J. C. D., Madsen, P., Behrens, C., Pettersson, I., Knudsen, L. B. & 2 others, Holst, Jens Juul & Lau, J., 2007, In: Bioorganic & Medicinal Chemistry Letters. 17, 19, p. 5472-5478 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Sulfonylurea compounds uncouple the glucose dependence of the insulinotropic effect of glucagon-like peptide 1.

    de Heer, J. & Holst, Jens Juul, 2007, In: Diabetes. 56, 2, p. 438-43 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Suppression of glucagon secretion is lower after oral glucose administration than during intravenous glucose administration in human subjects

    Meier, J. J., Deacon, Carolyn F., Schmidt, W. E., Holst, Jens Juul & Nauck, M. A., 2007, In: Diabetologia. 50, 4, p. 806-813 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    The dipeptidyl peptidase 4 inhibitor vildagliptin does not accentuate glibenclamide-induced hypoglycemia but reduces glucose-induced glucagon-like peptide 1 and gastric inhibitory polypeptide secretion

    Ouaghlidi, A. E., Rehring, E., Holst, Jens Juul, Schweizer, A., Foley, J., Holmes, D. & Nauck, M. A., 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 11, p. 4165-4171 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    The dipeptidyl peptidase IV inhibitor vildagliptin suppresses endogenous glucose production and enhances islet function after single-dose administration in type 2 diabetic patients.

    Balas, B., Baig, M. R., Watson, C., Dunning, B. E., Ligueros-Saylan, M., Wang, Y., He, Y., Darland, C., Holst, Jens Juul, Deacon, Carolyn F., Cusi, K., Mari, A., Foley, J. E. & DeFronzo, R. A., 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 4, p. 1249-55 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    The dipeptidyl peptidase-4 inhibitor vildagliptin improves beta-cell function and insulin sensitivity in subjects with impaired fasting glucose

    Utzschneider, K. M., Tong, J., Montgomery, B., Udayasankar, J., Gerchman, F., Marcovina, S. M., Watson, C. E., Ligueros-Saylan, M. A., Foley, J. E., Holst, Jens Juul, Deacon, Carolyn F. & Kahn, S. E., 2007, In: Diabetes Care. 31, 1, p. 108-113 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    The insulinotropic effect of GIP is impaired in patients with chronic pancreatitis and secondary diabetes mellitus as compared to patients with chronic pancreatitis and normal glucose tolerance.

    Knop, F. K., Vilsbøll, Tina, Højberg, P. V., Larsen, S., Madsbad, Sten, Holst, Jens Juul & Krarup, T., 2007, In: Regulatory Peptides. 144, 1-3, p. 123-30 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    The intestinotrophic peptide, glp-2, counteracts intestinal atrophy in mice induced by the epidermal growth factor receptor inhibitor, gefitinib.

    Hare, K. J., Hartmann, B., Kissow, Hannelouise, Holst, Jens Juul & Poulsen, Steen Seier, 2007, In: Clinical Cancer Research. 13, 17, p. 5170-5 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    The physiology of glucagon-like peptide 1.

    Holst, Jens Juul, 2007, In: Physiological Reviews. 87, 4, p. 1409-39 30 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. 2006
  44. Published

    Glucagon-like peptide 2 inhibits ghrelin secretion in humans

    Banasch, M., Bulut, K., Hagemann, D., Schrader, H., Holst, Jens Juul, Schmidt, W. E. & Meier, J. J., 10 Dec 2006, In: Regulatory Peptides. 137, 3, p. 173-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Impact of incretin hormones on beta-cell function in subjects with normal or impaired glucose tolerance

    Muscelli, E., Mari, A., Natali, A., Astiarraga, B. D., Camastra, S., Frascerra, S., Holst, Jens Juul & Ferrannini, E., Dec 2006, In: American Journal of Physiology: Endocrinology and Metabolism. 291, 6, p. E1144-50

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Synergistic effect of supplemental enteral nutrients and exogenous glucagon-like peptide 2 on intestinal adaptation in a rat model of short bowel syndrome

    Liu, X., Nelson, D. W., Holst, Jens Juul & Ney, D. M., Nov 2006, In: Uden navn. 84, 5, p. 1142-50 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Vagal afferents are essential for maximal resection-induced intestinal adaptive growth in orally fed rats

    Nelson, D. W., Liu, X., Holst, Jens Juul, Raybould, H. E. & Ney, D. M., Nov 2006, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 291, 5, p. R1256-64

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Wheat-fibre-induced changes of postprandial peptide YY and ghrelin responses are not associated with acute alterations of satiety

    Weickert, M. O., Spranger, J., Holst, Jens Juul, Otto, B., Koebnick, C., Möhlig, M. & Pfeiffer, A. F. H., Nov 2006, In: The British Journal of Nutrition. 96, 5, p. 795-8 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Plasma dipeptidyl peptidase-IV activity in patients with type-2 diabetes mellitus correlates positively with HbAlc levels, but is not acutely affected by food intake

    Ryskjaer, J., Deacon, Carolyn F., Carr, R. D., Krarup, T., Madsbad, Sten, Holst, Jens Juul, Vilsbøll, Tina, Ryskjaer, J., Deacon, C. F., Carr, R. D., Krarup, T., Madsbad, Sten, Holst, J. J. & Vilsbøll, T., 1 Sep 2006, In: European Journal of Endocrinology. 155, 3, p. 485-93 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Ghrelin stimulates gastric emptying and hunger in normal-weight humans

    Levin, F., Edholm, T., Schmidt, P. T., Grybäck, P., Jacobsson, H., Degerblad, M., Höybye, C., Holst, Jens Juul, Rehfeld, Jens Frederik, Hellström, P. M. & Näslund, E., Sep 2006, In: The Journal of clinical endocrinology and metabolism. 91, 9, p. 3296-302 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Switching from insulin to oral sulfonylureas in patients with diabetes due to Kir6.2 mutations

    Pearson, E. R., Flechtner, I., Njølstad, P. R., Malecki, M. T., Flanagan, S. E., Larkin, B., Ashcroft, F. M., Klimes, I., Codner, E., Iotova, V., Slingerland, A. S., Shield, J., Robert, J., Holst, Jens Juul, Clark, P. M., Ellard, S., Søvik, O., Polak, M., Hattersley, A. T. & Neonatal Diabetes International Collaborative Group, N. D. I. C. G., 3 Aug 2006, In: New England Journal of Medicine. 355, 5, p. 467-77 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    The rate of intestinal glucose absorption is correlated with plasma glucose-dependent insulinotropic polypeptide concentrations in healthy men

    Wachters-Hagedoorn, R. E., Priebe, M. G., Heimweg, J. A. J., Heiner, A. M., Englyst, K. N., Holst, Jens Juul, Stellaard, F. & Vonk, R. J., Jun 2006, In: Journal of Nutrition. 136, 6, p. 1511-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Exendin-4, but not glucagon-like peptide-1, is cleared exclusively by glomerular filtration in anaesthetised pigs

    Simonsen, L., Holst, Jens Juul & Deacon, Carolyn F., Apr 2006, In: Diabetologia. 49, 4, p. 706-12 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Glucagon-like peptide 1 abolishes the postprandial rise in triglyceride concentrations and lowers levels of non-esterified fatty acids in humans

    Meier, J. J., Gethmann, A., Götze, O., Gallwitz, B., Holst, Jens Juul, Schmidt, W. E. & Nauck, M. A., Mar 2006, In: Diabetologia. 49, 3, p. 452-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Effect of a high-protein breakfast on the postprandial ghrelin response

    Blom, W. A. M., Lluch, A., Stafleu, A., Vinoy, S., Holst, Jens Juul, Schaafsma, G. & Hendriks, H. F. J., Feb 2006, Effect of a high-protein breakfast on the postprandial ghrelin response. Vol. 83. p. 211-20 10 p. (Uden navn).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  56. Published

    Glucagon-like peptide-1: from extract to agent. The Claude Bernard Lecture, 2005

    Holst, Jens Juul, Feb 2006, In: Diabetologia. 49, 2, p. 253-60 8 p.

    Research output: Contribution to journalJournal articleCommunication

  57. Published

    The metabolite generated by dipeptidyl-peptidase 4 metabolism of glucagon-like peptide-1 has no influence on plasma glucose levels in patients with type 2 diabetes

    Zander, M., Madsbad, Sten, Deacon, Carolyn F. & Holst, Jens Juul, Feb 2006, In: Diabetologia. 49, 2, p. 369-74 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Feeding an elemental diet vs a milk-based formula does not decrease intestinal mucosal growth in infant pigs

    Stoll, B., Price, P. T., Reeds, P. J., Chang, X., Henry, J. F., van Goudoever, J. B., Holst, Jens Juul & Burrin, D. G., 3 Jan 2006, In: Journal of Parenteral and Enteral Nutrition. 30, 1, p. 32-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    GLP-2 receptor localizes to enteric neurons and endocrine cells expressing vasoactive peptides and mediates increased blood flow

    Guan, X., Karpen, H. E., Stephens, J., Bukowski, J. T., Niu, S., Zhang, G., Stoll, B., Finegold, M. J., Holst, Jens Juul, Hadsell, D., Hadsell, D. L., Nichols, B. L. & Burrin, D. G., Jan 2006, In: Gastroenterology. 130, 1, p. 150-64 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Glucagon-like peptide 2 stimulates glucagon secretion, enhances lipid absorption, and inhibits gastric acid secretion in humans

    Meier, J. J., Nauck, M. A., Pott, A., Heinze, K., Goetze, O., Bulut, K., Schmidt, W. E., Gallwitz, B. & Holst, Jens Juul, Jan 2006, In: Gastroenterology. 130, 1, p. 44-54 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Diet- and colonization-dependent intestinal dysfunction predisposes to necrotizing enterocolitis in preterm pigs

    Sangild, Per Torp, Siggers, R. H., Schmidt, M., Elnif, J., Bjørnvad, Charlotte Reinhard, Thymann, Thomas, Grøndahl, M. L., Hansen, Axel Kornerup, Jensen, S. K., Boye, M., Moelbak, L., Buddington, R. K., Weström, B. R., Holst, Jens Juul & Burrin, D. G., 2006, In: Gastroenterology. 130, 6, p. 1776-1792 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Effect of a high-protein breakfast on the postprandial ghrelin response

    Blom, W. A. M., Lluch, A., Stafleu, A., Vinoy, S., Holst, Jens Juul, Schaafsma, G. & Hendriks, H. F. J., 2006, In: American Journal of Clinical Nutrition. 83, 2, p. 211-220 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Effect of single oral doses of sitagliptin, a dipeptidyl peptidase-4 inhibitor, on incretin and plasma glucose levels after an oral glucose tolerance test in patients with type 2 diabetes.

    Herman, G. A., Bergman, A., Stevens, C., Kotey, P., Yi, B., Zhao, P., Dietrich, B., Golor, G., Schrodter, A., Keymeulen, B., Lasseter, K. C., Kipnes, M. S., Snyder, K., Hilliard, D., Tanen, M., Cilissen, C., De Smet, M., de Lepeleire, I., Van Dyck, K., Wang, A. Q. & 7 others, Zeng, W., Davies, M. J., Tanaka, W., Holst, Jens Juul, Deacon, Carolyn F., Gottesdiener, K. M. & Wagner, J. A., 2006, In: Journal of Clinical Endocrinology and Metabolism. 91, 11, p. 4612-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Effects of PYY1-36 and PYY3-36 on appetite, energy intake, energy expenditure, glucose and fat metabolism in obese and lean subjects.

    Sloth, B., Holst, Jens Juul, Flint, A., Gregersen, N. T. & Astrup, A., 2006, In: American Journal of Physiology: Endocrinology and Metabolism. 292, 4, p. E1062-E1068 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Effects of gastric emptying on the postprandial ghrelin response

    Blom, W. A. M., Lluch, A., Vinoy, S., Stafleu, A., Berg, R. V. D., Holst, Jens Juul, Kok, F. J. & Hendriks, H. F. J., 2006, In: American Journal of Physiology: Endocrinology and Metabolism. 290, 2, p. E389-E395

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Exendin-4, but not glucagon-like peptide-1, is cleared exclusively by glomerular filtration in anaesthetised pigs

    Simonsen, L., Holst, Jens Juul & Deacon, Carolyn F., 2006, In: Diabetologia. 49, 4, p. 706-712 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Feeding an elemental diet vs a milk-based formula does not decrease intestinal mucosal growth in infant pigs

    Stoll, B., Price, P. T., Reeds, P. J., Chang, X., Henry, J. F., Goudoever, J. B. V., Holst, Jens Juul & Burrin, D. G., 2006, In: Journal of Parenteral and Enteral Nutrition. 30, 1, p. 32-39 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    GIP-(3-42) does not antagonize insulinotropic effects of GIP at physiological concentrations.

    Deacon, Carolyn F., Plamboeck, A., Rosenkilde, Mette, de Heer, J. & Holst, Jens Juul, 2006, In: American Journal of Physiology: Endocrinology and Metabolism. 291, 3, p. E468-75

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    GLP-2 receptor localizes to enteric neurons and endocrine cells expressing vasoactive peptides and mediates increased blood flow

    Guan, X. F., Karpen, H. E., Stephens, J., Bukowski, J. T., Niu, S. Y., Zhang, G. C., Stoll, B., Finegold, M. J., Holst, Jens Juul, Hadsell, D. L., Nichols, B. L. & Burrin, D. G., 2006, In: Today in Medicine. Gastroenterology. 130, 1, p. 150-164 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Ghrelin stimulates gastric emptying and hunger in normal-weight humans

    Levin, F., Edholm, T., Schmidt, P. T., Gryback, P., Jacobsson, H., Degerblad, M., Hoybye, C., Holst, Jens Juul, Rehfeld, J. F., Hellstrom, P. M. & Naslund, E., 2006, In: Journal of Clinical Endocrinology and Metabolism. 91, 9, p. 3296-3302 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Glucagon-like peptide 1 abolishes the postprandial rise in triglyceride concentrations and lowers levels of non-esterified fatty acids in humans

    Meier, J. J., Gethmann, A., Gotze, O., Gallwitz, B., Holst, Jens Juul, Schmidt, W. E. & Nauck, M. A., 2006, In: Diabetologia. 49, 3, p. 452-458 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    Glucagon-like peptide 2 stimulates glucagon secretion, enhances lipid absorption, and inhibits gastric acid secretion in humans

    Meier, J. J., Nauck, M. A., Pott, A., Heinze, K., Goetze, O., Bulut, K., Schmidt, W. E., Gallwitz, B. & Holst, Jens Juul, 2006, In: Today in Medicine. Gastroenterology. 130, 1, p. 44-54 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Glucagon-like peptide-1: From extract to agent. The Claude Bernard Lecture, 2005

    Holst, Jens Juul, 2006, In: Diabetologia. 49, 2, p. 253-260 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Glucagon-like peptides 1 and 2, enteroglucagon, glicentin and oxyntomodulin.

    Holst, Jens Juul & Kastin, A., 2006, Handbook of biologically active peptides. Amsterdam: Elsevier, p. 1057-1064 7 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  75. Published

    Glucose-stimulated prehepatic insulin secretion is associated with circulating alanine, triglyceride, glucagons, lactate and TNF-alfa in patients with HIV-lipodystrophy

    Haugaard, S. B., Andersen, Ove, Pedersen, S., Dela, Flemming, Holst, Jens Juul, Deacon, Carolyn F., Iversen, J. & Madsbad, Sten, 2006, In: HIV Medicine. 7, p. 163-172 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Glycemic and insulinemic responses as determinants of appetite in humans

    Flint, A., Møller, B. K., Raben, Anne, Sloth, B., Pedersen, D., Tetens, Inge , Holst, Jens Juul & Astrup, A., 2006, In: American Journal of Clinical Nutrition. 84, 6, p. 1365-1373 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Immunoneutralization of endogenous glucagon reduces hepatic glucose output and improves long-term glycemic control in diabetic ob/ob mice.

    Sørensen, H., Brand, C. L., Neschen, S., Holst, Jens Juul, Fosgerau, K., Nishimura, E. & Shulman, G. I., 2006, In: Diabetes. 55, 10, p. 2843-8 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Impact of incretin hormones on beta-cell function in subjects with normal or impaired glucose tolerance

    Muscelli, E., Mari, A., Natali, A., Astiarraga, B. D., Camastra, S., Frascerra, S., Holst, Jens Juul & Ferrannini, E., 2006, In: American Journal of Physiology: Endocrinology and Metabolism. 291, 6, p. E1144-E1150

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Increased postprandial responses of GLP-1 and GIP in patients with chronic pancreatitis and steatorrhea following pancreatic enzyme substitution.

    Knop, F. K., Vilsbøll, Tina, Larsen, S., Højberg, P. V., Vølund, A., Madsbad, Sten, Holst, Jens Juul & Krarup, T., 2006, In: American Journal of Physiology: Endocrinology and Metabolism. 292, 1, p. E324-30

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    Incretin mimetics in the treatment of type 2 diabetes mellitus

    Holst, Jens Juul & Hughes, T., 2006, European Endocrine Disease 2006. London: Touch Briefings, p. 17-19 2 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  81. Published

    Influence of gastric inhibitory polypeptide on pentagastrin-stimulated gastric acid secretion in patients with type 2 diabetes and healthy controls.

    Meier, J. J., Nauck, M. A., Kask, B., Holst, Jens Juul, Deacon, Carolyn F., Schmidt, W. E. & Gallwitz, B., 2006, In: World Journal of Gastroenterology. 12, 12, p. 1874-80 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Inhibitory effect of GLP-1 on gastric motility persists after vagal deafferentation in pigs.

    Nagell, C. F., Wettergren, A., Ørskov, Cathrine & Holst, Jens Juul, 2006, In: Scandinavian Journal of Gastroenterology. 41, 6, p. 667-72 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Metabolism of glucagon-like peptide-2 in pigs: role of dipeptidyl peptidase IV.

    Hansen, L., Hare, K. J., Hartmann, B., Deacon, Carolyn F., Ugleholdt, Randi Kjærsgaard, Plamboeck, A. & Holst, Jens Juul, 2006, In: Regulatory Peptides. 138, 2-3, p. 126-32 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Possible role of adiponectin and insulin sensitivity in mediating the favorable effects of lower body fat mass on blood lipids

    Buemann, B., Astrup, A., Pedersen, O., Black, E., Holst, C., Toubro, S., Echwald, S., Holst, Jens Juul, Rasmussen, C. & Sørensen, Thorkild I.A., 2006, In: Journal of Clinical Endocrinology and Metabolism. 91, 5, p. 1698-1704 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Prohormone convertase 1/3 is essential for processing of the glucose-dependent insulinotropic polypeptide precursor

    Ugleholdt, Randi Kjærsgaard, Poulsen, M. H., Holst, Peter Johannes, Irminger, J., Orskov, C., Pedersen, Jens, Rosenkilde, Mette, Zhu, X., Steiner, D. F. & Holst, Jens Juul, 2006, In: Journal of Biological Chemistry. 281, 16, p. 11050-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Role of GLP-1 analogues and DDP-IV inhibitors in the treatment of type 2 diabetes

    Holst, Jens Juul & Deacon, Carolyn F., 2006, In: Avances en Diabetologia. 22, 2, p. 115-125 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Stimulation of glucagon secretion and inhibition of gastric acid secretion by glucagon-like peptide-2 (GLP-2) in healthy human subjects

    Meier, J., Nauck, M. A., Pott, A., Heinze, K., Götze, O., Bulut, K., Schmidt, W. E., Gallwitz, B. & Holst, Jens Juul, 2006, In: Today in Medicine. Gastroenterology. 130, p. 44-54

    Research output: Contribution to journalJournal articleResearch

  88. Published

    Switching from insulin to oral sulfonylureas in patients with diabetes due to Kir6.2 mutations

    Pearson, E. R., Flechtner, I., Njolstad, P. R., Malecki, M. T., Flanagan, S. E., Larkin, B., Ashcroft, F. M., Klimes, I., Codner, E., Iotova, V., Slingerland, A. S., Shield, J., Robert, J., Holst, Jens Juul, Clark, P. M., Ellard, S., Sovik, O., Polak, M. & Hattersley, A. T., 2006, In: New England Journal of Medicine. 355, 5, p. 467-477 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Synergistic effect of supplemental enteral nutrients and exogenous glucagon-like peptide 2 on intestinal adaptation in a rat model of short bowel syndrome

    Liu, X. W., Nelson, D. W., Holst, Jens Juul & Ney, D. M., 2006, In: American Journal of Clinical Nutrition. 84, 5, p. 1142-1150 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    The effect o a high protein dairy breakfast on the postprandial ghrelin response

    Blom, W. A. M., Lluch, A., Stafleu, A., Vinoy, S., Holst, Jens Juul, Schaafsma, G. & Hendriks, H. F. K., 2006, In: Am. J. Clin. Nutr.. 83, p. 211-220

    Research output: Contribution to journalJournal articleResearch

  91. Published

    The effects of gastric emptying on the postprandial ghrelin response

    Blom, W., Lluch, A., Vinoy, S., Stafleu, A., Van den Berg, R., Holst, Jens Juul, Kok, F. J. & Hendriks, H. F. K., 2006, In: Am. J. Physiol.. 290, p. E389-E395

    Research output: Contribution to journalJournal articleResearch

  92. Published

    The elimination rates of intact GIP as well as its primary metabolite, GIP 3-42, are similar in type 2 diabetic patients and healthy subjects.

    Vilsbøll, Tina, Agersø, H., Lauritsen, T., Deacon, Carolyn F., Aaboe, K., Madsbad, Sten, Krarup, T. & Holst, Jens Juul, 2006, In: Regulatory Peptides. 137, 3, p. 168-72 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    The glucagon-like peptide-1 metabolite GLP-1-(9-36) amide reduces postprandial glycemia independently of gastric emptying and insulin secretion in humans.

    Meier, J. J., Gethmann, A., Nauck, M. A., Götze, O., Schmitz, F., Deacon, Carolyn F., Gallwitz, B., Schmidt, W. E. & Holst, Jens Juul, 2006, In: American Journal of Physiology: Endocrinology and Metabolism. 290, 6, p. E1118-23

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    The metabolite generated by dipeptidyl-peptidase 4 metabolism of glucagon-like peptide-1 has no influence on plasma glucose levels in patients with type 2 diabetes

    Zander, M., Madsbad, S., Deacon, Carolyn F. & Holst, Jens Juul, 2006, In: Diabetologia. 49, 2, p. 369-374 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    The rate of intestinal glucose absorption is correlated with plasma glucose-dependent insulinotropic polypeptide concentrations in healthy men

    Wachters-Hagedoorn, R. E., Priebe, M. G., Heimweg, J. A. J., Heiner, A. M., Englyst, K. N., Holst, Jens Juul, Stellaard, F. & Vonk, R. J., 2006, In: Journal of Nutrition. 136, 6, p. 1511-1516 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    The successful transfer of insulin treated patients with diabetes due to Kir6.2 (KCNJ11) mutations to oral sulfonylureas

    Pearson, E. R., Flechtner, I., Njølståd, P. R., Malecki, M. T., Flanagan, S., Larkin, B., Ashcroft, F. M., Klimes, I., Codner, E., Iotova, V., Slingerland, A. S., Shield, J., Robert, J. J., Holst, Jens Juul, Clark, P. M., Ellard, S. E., Sovik, O., Polak, M. & Hattersley, A. T., 2006, In: N. Engl. J. Med.. 355, p. 467-477

    Research output: Contribution to journalJournal articleResearch

  97. Published

    Vagal afferents are essential for maximal resection-induced intestinal adaptive growth in orally fed rats

    Nelson, D. W., Liu, X. W., Holst, Jens Juul, Raybould, H. E. & Ney, D. M., 2006, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 291, 5, p. R1256-R1264

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    Wheat-fibre-induced changes of postprandial peptide YY and ghrelin responses are not associated with acute alterations of satiety

    Weickert, M. O., Spranger, J., Holst, Jens Juul, Otto, B., Koebnick, C., Moehlig, M. & Pfeiffer, A. F. H., 2006, In: British Journal of Nutrition. 96, 5, p. 795-798 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. 2005
  100. Published

    Exenatide augments first- and second-phase insulin secretion in response to intravenous glucose in subjects with type 2 diabetes

    Fehse, F., Trautmann, M., Holst, Jens Juul, Halseth, A. E., Nanayakkara, N., Nielsen, L. L., Fineman, M. S., Kim, D. D. & Nauck, M. A., Nov 2005, In: The Journal of clinical endocrinology and metabolism. 90, 11, p. 5991-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  101. Published

    Impact of cereal fibre on glucose-regulating factors

    Weickert, M. O., Mohlig, M., Koebnick, C., Holst, Jens Juul, Namsolleck, P., Ristow, M., Osterhoff, M., Rochlitz, H., Rudovich, N., Spranger, J. & Pfeiffer, A. F. H., Nov 2005, In: Diabetologia. 48, 11, p. 2343-53 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  102. Published

    Severe hypoglycaemia post-gastric bypass requiring partial pancreatectomy: evidence for inappropriate insulin secretion and pancreatic islet hyperplasia

    Patti, M. E., McMahon, G., Mun, E. C., Bitton, A., Holst, Jens Juul, Goldsmith, J., Hanto, D. W., Callery, M., Arky, R., Nose, V., Bonner-Weir, S. & Goldfine, A. B., Nov 2005, In: Diabetologia. 48, 11, p. 2236-40 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  103. Published

    A role for pancreatic polypeptide in the regulation of gastric emptying and short-term metabolic control

    Schmidt, P. T., Näslund, E., Grybäck, P., Jacobsson, H., Holst, Jens Juul, Hilsted, Linda & Hellström, P. M., Sep 2005, In: The Journal of clinical endocrinology and metabolism. 90, 9, p. 5241-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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