Thomas Mandrup-Poulsen

Thomas Mandrup-Poulsen

Professor

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    1. 2019
    2. Published

      Gluten under graviditeten og risiko for type 1 diabetes hos barnet: [Medicinsk nyhed]

      Mandrup-Poulsen, Thomas, 2019, In: Ugeskrift for Laeger. 22

      Research output: Contribution to journal › Comment/debate › Communication

    3. Published

      Inflammatory and metabolic stress perturbs the beta cell circadian clock: [Meeting Abstract]

      Andersen, Phillip Alexander Keller, Rose, P. H., Koomen, M., Petrenko, V., Dahlby, T., Ghiasi, S. M., Dibner, C. & Mandrup-Poulsen, Thomas, 2019, In: Diabetologia. 62, Supl. 1/SI, p. S120-S120 237.

      Research output: Contribution to journal › Conference abstract in journal › Research

    4. Published

      Limited benefit of haemoglobin glycation index as risk factor for cardiovascular disease in type 2 diabetes patients

      Østergaard, H. B., Mandrup-Poulsen, Thomas, Berkelmans, G. F. N., van der Graaf, Y., Visseren, F. L. J. & Westerink, J., 2019, In: Diabetes and Metabolism. 45, 3, p. 254-260 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Neuromedin U Does Not Act as a Decretin in Rats

      Kuhre, Rune Ehrenreich, Christiansen, Charlotte Bayer, Ghiasi, S. M., Gabe, M. B. N., Skat-Rørdam, P. A., Modvig, Ida Marie, Mandrup-Poulsen, Thomas, Albrechtsen, Reidar, Rosenkilde, Mette, Hartmann, Bolette, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2019, In: Cell Metabolism. 29, 3, p. 719-726.e1-e5 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      No direct effect of SGLT2 activity on glucagon secretion

      Kuhre, Rune Ehrenreich, Ghiasi, S. M., Adriaenssens, A. E., Albrechtsen, Nicolai Jacob Wewer, Andersen, Daniel Bjørklund, Aivazidis, A., Chen, L., Mandrup-Poulsen, Thomas, Ørskov, Cathrine, Gribble, F. M., Reimann, F., Wierup, N., Tyrberg, B. & Holst, Jens Juul, 2019, In: Diabetologia. 62, 6, p. 1011-1023

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Targeting innate immune mediators in type 1 and type 2 diabetes

      Donath, M. Y., Dinarello, C. A. & Mandrup-Poulsen, Thomas, 2019, In: Nature Reviews. Immunology. 19, 12, p. 734-746

      Research output: Contribution to journal › Review › Research › peer-review

    8. Published

      The Lysine Demethylase KDM5B Regulates Islet Function and Glucose Homeostasis

      Backe, M. B., Jin, C., Andreone, L., Sankar, A., Agger, K., Helin, K., Madsen, A. N., Poulsen, Steen Seier, Bysani, M., Bacos, K., Ling, C., Javier Perone, M., Holst, Birgitte & Mandrup-Poulsen, Thomas, 2019, In: Journal of Diabetes Research. 2019, 15 p., 5451038.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Treatment of type 2 diabetes by targeting interleukin-1: a meta-analysis of 2921 patients

      Kataria, Y., Ellervik, Christina & Mandrup-Poulsen, Thomas, 2019, In: Seminars in Immunopathology. 41, 4, p. 413-425

      Research output: Contribution to journal › Review › Research › peer-review

    10. 2018
    11. Published

      MicroRNAs and histone deacetylase inhibition-mediated protection against inflammatory β-cell damage

      Vestergaard, A. L., Bang-Berthelsen, C. H., Floyel, T., Stahl, J. L., Christen, L., Sotudeh, F. T., Horskjaer, P. D. H., Frederiksen, K. S., Kofod, F. G., Bruun, C., Berchtold, L. A., Storling, J., Regazzi, R., Kaur, S., Pociot, Flemming & Mandrup-Poulsen, Thomas, 27 Sep 2018, In: PLOS ONE. 13, 9, p. 1-22 22 p., e0203713 .

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Oral histone deacetylase inhibitor synergises with T cell targeted immunotherapy to preserve beta cell metabolic function and induce stable remission of new-onset autoimmune diabetes in NOD mice

      Besançon, A., Goncalves, T., Valette, F., Dahllöf, M. S., Mandrup-Poulsen, Thomas, Chatenoud, L. & You, S., 1 Feb 2018, In: Diabetologia. 61, 2, p. 389-398 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Immunometabolism in 2017: Metabolism and the inflammasome in health and ageing

      Mandrup-Poulsen, Thomas, Feb 2018, In: Nature Reviews Endocrinology. 14, 2, p. 72-74 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Lysine demethylase inhibition protects pancreatic β cells from apoptosis and improves β-cell function

      Backe, M. B., Andersson, J. L., Bacos, K., Christensen, D. P., Hansen, J. B., Dorosz, J. J., Gajhede, Michael, Dahlby, T., Bysani, M., Kristensen, L. H., Ling, C., Olsen, L. & Mandrup-Poulsen, Thomas, 15 Jan 2018, In: Molecular and Cellular Endocrinology. 460, p. 47-56 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Acute administration of interleukin-6 does not increase secretion of glucagon-like peptide-1 in mice

      Christiansen, Charlotte Bayer, Jepsen, Sara Lind, Svendsen, B., Balk-Møller, E., Dahlby, T., Kuhre, Rune Ehrenreich, Hartmann, Bolette, Mandrup-Poulsen, Thomas, Deacon, Carolyn F., Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2018, In: Physiological Reports. 6, 13, p. 1-8 e13788.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Effect of Hydrolyzed Infant Formula vs Conventional Formula on Risk of Type 1 Diabetes: The TRIGR Randomized Clinical Trial

      TRIGR Study Group, T. S. G., 2018, In: J A M A: The Journal of the American Medical Association. 319, 1, p. 38-48

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Glucolipotoxic conditions induce beta-cell iron import, cytosolic ROS formation and apoptosis

      Hansen, J. B., Dos Santos, L. R. B., Liu, Y., Prentice, K. J., Teudt, F., Tonnesen, M., Jonas, J., Wheeler, M. B. & Mandrup-Poulsen, Thomas, 2018, In: Journal of Molecular Endocrinology. 61, 2, p. 69-77

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Increased Plasma Ferritin Concentration and Low-Grade Inflammation-A Mendelian Randomization Study

      Moen, I. W., Bergholdt, H. K. M., Mandrup-Poulsen, Thomas, Nordestgaard, Børge & Ellervik, Christina, 2018, In: Clinical Chemistry. 64, 2, p. 374-385 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Interleukin-37 treatment of mice with metabolic syndrome improves insulin sensitivity and reduces pro-inflammatory cytokine production in adipose tissue

      Ballak, D. B., Li, S., Cavalli, G., Stahl, J. L., Tengesdal, I. W., van Diepen, J. A., Kluck, V., Swartzwelter, B., Azam, T., Tack, C. J., Stienstra, R., Mandrup-Poulsen, Thomas, Seals, D. R. & Dinarello, C. A., 2018, In: Journal of Biological Chemistry. 293, 37, p. 14224-14236

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Iron Status and Gestational Diabetes: A Meta-Analysis

      Kataria, Y., Wu, Y., Horskjaer, P. D. H., Mandrup-Poulsen, Thomas & Ellervik, Christina, 2018, In: Nutrients. 10, 5, 15 p., 621 .

      Research output: Contribution to journal › Review › Research › peer-review

    21. Published

      Regulation of the beta-cell inflammasome and contribution to stress-induced cellular dysfunction and apoptosis

      Ghiasi, S. M., Dahllöf, M. S., Osmai, Y., Osmai, M., Jakobsen, K. K., Aivazidis, A., Tyrberg, B., Perruzza, L., Prause, Michala Cecilie Burstein, Christensen, D. P., Fog-Tonnesen, M., Lundh, M., Grassi, F., Chatenoud, L. & Mandrup-Poulsen, Thomas, 2018, In: Molecular and Cellular Endocrinology. 478, p. 106-114

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      The No-Go and Nonsense-Mediated RNA Decay Pathways Are Regulated by Inflammatory Cytokines in Insulin-Producing Cells and Human Islets and Determine β-Cell Insulin Biosynthesis and Survival

      Ghiasi, S. M., Krogh, Nicolai, Tyrberg, B. & Mandrup-Poulsen, Thomas, 2018, In: Diabetes. 67, 10, p. 2019-2037 19 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. 2017
    24. Published

      Cardiovascular and All-Cause Mortality Risk Associated With Urinary Excretion of 8-oxoGuo, a Biomarker for RNA Oxidation, in Patients With Type 2 Diabetes: A Prospective Cohort Study

      Kjær, L. K., Cejvanovic, V., Henriksen, T., Petersen, K. M., Hansen, Torben, Pedersen, Oluf Borbye, Christensen, C. K., Torp-Pedersen, C., Gerds, Thomas Alexander, Brandslund, I., Mandrup-Poulsen, Thomas & Poulsen, Henrik Enghusen, Dec 2017, In: Diabetes Care. 40, 12, p. 1771-1778 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Granzyme A in the Pathogenesis of Type 1 Diabetes: The Yes and the No

      Mandrup-Poulsen, Thomas, Dec 2017, In: Diabetes. 66, 12, p. 2937-2939 3 p.

      Research output: Contribution to journal › Letter › Research › peer-review

    26. Published

      A guiding map for inflammation

      Netea, M. G., Balkwill, F., Chonchol, M., Cominelli, F., Donath, M. Y., Giamarellos-Bourboulis, E. J., Golenbock, D., Gresnigt, M. S., Heneka, M. T., Hoffman, H. M., Hotchkiss, R., Joosten, L. A. B., Kastner, D. L., Korte, M., Latz, E., Libby, P., Mandrup-Poulsen, T., Mantovani, A., Mills, K. H. G., Nowak, K. L. & 12 others, O'Neill, L. A., Pickkers, P., van der Poll, T., Ridker, P. M., Schalkwijk, J., Schwartz, D. A., Siegmund, B., Steer, C. J., Tilg, H., van der Meer, J. W. M., van de Veerdonk, F. L. & Dinarello, C. A., 19 Jul 2017, In: Nature Immunology. 18, 8, p. 826-831 6 p.

      Research output: Contribution to journal › Comment/debate › Research › peer-review

    27. Published

      The immunoproteasome is induced by cytokines and regulates apoptosis in human islets

      Lundh, M., Bugliani, M., Dahlby, T., Chou, D. H., Wagner , B., Ghiasi, S. M., De Tata, V., Chen, Z., Lund, Marianne N., Davies, Michael J., Marchetti, P. & Mandrup-Poulsen, Thomas, 2017, In: Journal of Endocrinology. 233, 3, p. 369-379 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. 2016
    29. Published

      Iron Regulation of Pancreatic Beta-Cell Functions and Oxidative Stress

      Backe, M. B., Moen, I. W., Ellervik, Christina, Hansen, J. B. & Mandrup-Poulsen, Thomas, 17 Jul 2016, In: Annual Review of Nutrition. 36, p. 241-273 33 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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    ID: 923693