Jens Juul Holst

Jens Juul Holst

Professor

ORCID: 0000-0001-6853-3805

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  1. Published

    The L-alpha-amino acid receptor GPRC6A is expressed in the islets of Langerhans but is not involved in L-arginine-induced insulin release

    Smajilovic, S., Clemmensen, Christoffer, Johansen, L. D., Wellendorph, Petrine, Holst, Jens Juul, Thams, P. G., Ogo, E. & Bräuner, Hans, 2013, In: Amino Acids. 44, 2, p. 383-390 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    The Gut: A Key to the Pathogenesis of Type 2 Diabetes?

    Holst, Jens Juul, Pedersen, Jens, Albrechtsen, Nicolai Jacob Wewer & Knop, Filip Krag, Aug 2017, In: Metabolic Syndrome and Related Disorders. 15, 6, p. 259-262 4 p.

    Research output: Contribution to journal › Review › Research › peer-review

  3. Published

    The Gluco- and Liporegulatory and Vasodilatory Effects of Glucose-Dependent Insulinotropic Polypeptide (GIP) Are Abolished by an Antagonist of the Human GIP Receptor

    Asmar, M., Asmar, A., Simonsen, L., Gasbjerg, Lærke Smidt, wbf943, wbf943, Rosenkilde, Mette, Hartmann, Bolette, Dela, Flemming, Holst, Jens Juul & Bülow, J., Sep 2017, In: Diabetes. 66, 9, p. 2363-2371 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    The Glucagon Receptor Antagonist LY2409021 has No Effect on Postprandial Glucose in Type 2 Diabetes

    Hædersdal, S., Lund, A., Maagensen, H., Nielsen-Hannerup, E., Gasbjerg, Lærke Smidt, Rosenkilde, Mette, Forman, Julie Lyng, van Hall, Gerrit, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2022, In: European Journal of Endocrinology. 186, 2, p. 207-221 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    The GLP-1 receptor agonist lixisenatide reduces postprandial glucose in patients with diabetes secondary to total pancreatectomy: a randomised, placebo-controlled, double-blinded crossover trial

    Juel, C. T. B., Lund, A., Andersen, M. M., Hansen, C. P., Storkholm, J. H., Rehfeld, Jens Frederik, van Hall, G., Hartmann, Bolette, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Jul 2020, In: Diabetologia. 63, p. 1285-1298

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    The Effect of PCSK1 Variants on Waist, Waist-Hip Ratio and Glucose Metabolism Is Modified by Sex and Glucose Tolerance Status

    Gjesing, A. P., Vestmar, M. A., Jørgensen, T., Heni, M., Holst, Jens Juul, Witte, D. R., Hansen, Torben & Pedersen, Oluf Borbye, 1 Jan 2011, In: P L o S One. 6, 9, p. e23907 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    The Effect of Exogenous GLP-1 on Food Intake is Lost in Male Truncally Vagotomized Subjects with Pyloroplasty

    Plamboeck, A., Veedfald, Simon, Deacon, Carolyn F., Hartmann, Bolette, Wettergren, A., Svendsen, Lars Bo, Meisner, S., Hovendahl, C., Vilsbøll, Tina, Knop, Filip Krag & Holst, Jens Juul, 18 Apr 2013, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 304, p. G1117-G1127 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    The CTRB1/2 locus affects diabetes susceptibility and treatment via the incretin pathway

    't Hart, L. M., Fritsche, A., Nijpels, G., van Leeuwen, N., Donnelly, L. A., Dekker, J. M., Alssema, M., Fadista, J., Carlotti, F., Gjesing, A. P., Palmer, C. N. A., van Haeften, T. W., Herzberg-Schäfer, S. A., Simonis-Bik, A. M. C., Houwing-Duistermaat, J. J., Helmer, Q., Deelen, J., Guigas, B., Hansen, T., Machicao, F. & 14 others, Willemsen, G., Heine, R. J., Kramer, M., Holst, Jens Juul, de Koning, E. J. P., Häring, H., Pedersen, Oluf Borbye, Groop, L., de Geus, E. J. C., Slagboom, P. E., Boomsma, D. I., Eekhoff, E. M. W., Pearson, E. R. & Diamant, M., 14 May 2013, In: Diabetes. 62, 9, p. 3275-3281 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    The C-terminal extension of exendin-4 provides additional metabolic stability when added to GLP-1, while there is minimal effect of truncating exendin-4 in anaesthetized pigs

    Simonsen, L., Holst, Jens Juul, Madsen, K. & Deacon, Carolyn F., 10 Feb 2013, In: Regulatory Peptides. 181, 10, p. 17-21 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    The 2-monoacylglycerol moiety of dietary fat appears to be responsible for the fat-induced release of GLP-1 in humans.

    Mandøe, M. J., Hansen, K. B., Hartmann, Bolette, Rehfeld, Jens Frederik, Holst, Jens Juul & Hansen, Harald S., 2015, In: The American Journal of Clinical Nutrition. 102, 3, p. 548-555 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Temporal changes in the intestinal growth promoting effects of glucagon-like peptide 2 following intestinal resection

    Kaji, T., Tanaka, H., Redstone, H., Wallace, L. E., Holst, Jens Juul & Sigalet, D. L., 2008, In: Journal of Surgical Research. 152, 2, p. 271-80 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Teduglutide (ALX-0600), a dipeptidyl-peptidase-IV resistant glucagon-like-2 analog improves intestinal function in short bowel syndrome patients

    Jeppesen, P. B., Sanguinetti, E. L., Buckman, A., Howard, L., Scolapio, J. S., Ziegler, T. R., Gregory, M., Tappendent, K. A., Holst, Jens Juul & Mortensen, P. B., 2005, In: Gut. 54, p. 1224-1231

    Research output: Contribution to journal › Journal article › Research

  13. Published

    Targeting the intestinal L-cell for obesity and type 2 diabetes treatment

    Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Deacon, Carolyn F. & Holst, Jens Juul, 1 Jan 2014, In: Expert Review of Endocrinology & Metabolism. 9, 1, p. 61-72 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Tachykinins stimulate the release of peptide hormones (glucagon-like peptide-1), and paracrine - (somatostatin) and neurotransmitters (vasoactive intestinal polypeptide) from porcine ileum through NK-1 receptors

    Schmidt, P. T., Rickelt, L. F. & Holst, Jens Juul, 1999, In: Digestive Diseases and Sciences. 44, p. 1273-1281

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Tachykinins stimulate acid and pepsinogen secretion in the isolated perfused porcine stomach

    Schmidt, P. T., Rasmussen, T. N. & Holst, Jens Juul, 1999, In: Acta Physiologica (Print Edition). 166, p. 335-340

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Tachykinins mediate vagal inhibition of gastrin secretion in pigs

    Schmidt, P., Poulsen, Steen Seier, Hilsted, Linda, Rasmussen, T. N. & Holst, Jens Juul, Oct 1996, In: Gastroenterology. 111, 4, p. 925-35 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Tachykinins in the regulation of gastric motility and secretion

    Schmidt, P. T. & Holst, Jens Juul, 2000, In: Review Cellular and Molecular Life Sciences. 57, p. 579-588

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Tachykinins in the porcine pancreas: potent exocrine and endocrine effects via NK-1 receptors

    Schmidt, P. T., Tornøe, K., Poulsen, Steen Seier, Nygaard, T. & Holst, Jens Juul, 2000, In: Pancreas. 20, p. 241-247

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Tachykinins in the porcine pancreas: potent exocrine and endocrine effects via NK-1 receptors

    Schmidt, P. T., Tornøe, K., Poulsen, Steen Seier, Rasmussen, T. N. & Holst, Jens Juul, Apr 2000, In: Pancreas. 20, 3, p. 241-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    TRPV1: A Potential Therapeutic Target in Type 2 Diabetes and Comorbidities?

    Gram, D. X., Holst, Jens Juul & Szallasi, A., Nov 2017, In: Trends in Molecular Medicine. 23, 11, p. 1002-1013 12 p.

    Research output: Contribution to journal › Review › Research › peer-review

  21. Published

    THERAPY OF ENDOCRINE DISEASE: Amylin and calcitonin - physiology and pharmacology

    Mathiesen, D. S., Lund, A., Holst, Jens Juul, Knop, Filip Krag, Lutz, T. A. & Bagger, J. I., 2022, In: European Journal of Endocrinology. 186, 6, p. R93-R111

    Research output: Contribution to journal › Review › Research › peer-review

  22. Published

    Systems signatures reveal unique remission-path of Type 2 diabetes following Roux-en-Y gastric bypass surgery

    Li, Q-R., Wang, Z-M., Albrechtsen, N. J. W., Wang, D-D., Su, Z-D., Gao, X-F., Wu, Q-Q., Zhang, H-P., Zhu, L., Li, R-X., Jacobsen, S., Jørgensen, N. B., Dirksen, C., Bojsen-Møller, K. N., Petersen, J. S., Madsbad, S., Clausen, T. R., Diderichsen, B., Chen, L-N., Holst, J. J. & 2 others, Zeng, R. & Wu, J., 2018, In: EBioMedicine. 28, p. 234-240 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Synergistic effect of supplemental enteral nutrients and exogenous glucagon-like peptide 2 on intestinal adaptation in a rat model of short bowel syndrome

    Liu, X., Nelson, D. W., Holst, Jens Juul & Ney, D. M., Nov 2006, In: Uden navn. 84, 5, p. 1142-50 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Synergistic effect of supplemental enteral nutrients and exogenous glucagon-like peptide 2 on intestinal adaptation in a rat model of short bowel syndrome

    Liu, X. W., Nelson, D. W., Holst, Jens Juul & Ney, D. M., 2006, In: American Journal of Clinical Nutrition. 84, 5, p. 1142-1150 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Sympathoadrenal regulation of adrenocortical steroidogenesis

    Ehrhart-Bornstein, M., Bornstein, S. R., Gonzalez-Hernandez, J., Holst, Jens Juul, Watermann, M. R. & Scherbaum, W. A., 1995, In: Endocrine Research. 21, p. 13-24

    Research output: Contribution to journal › Journal article › Research › peer-review

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