Morten Steen Salling Olesen

Morten Steen Salling Olesen

Professor MSO


  1. Published

    Whole-genome amplified DNA from stored dried blood spots is reliable in high resolution melting curve and sequencing analysis

    Winkel, B. G., Hollegaard, M. V., Olesen, Morten Steen Salling, Svendsen, Jesper Hastrup, Haunsø, Stig, Hougaard, D. M. & Tfelt-Hansen, J., 9 Feb 2011, In: BMC Medical Genetics. 12, p. 22

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Whole-Exome Sequencing Implicates Neuronal Calcium Channel with Familial Atrial Fibrillation

    Vad, Oliver Tim Bundgaard, Yan, Y., Denti, F., Ahlberg, Gustav, Refsgaard, L., Bomholtz, Sofia Hammami, Santos, J. L., Rasmussen, Simon, Haunsø, Stig, Svendsen, Jesper Hastrup, Christophersen, I. E., Schmitt, Nicole, Olesen, Morten Steen Salling & Bentzen, Bo Hjorth, 2022, In: Frontiers in Genetics. 13, 8 p., 806429.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published
  4. Published

    Very early-onset lone atrial fibrillation patients have a high prevalence of rare variants in genes previously associated with atrial fibrillation

    Olesen, Morten Steen Salling, Andreasen, Laura Korsholm, Jabbari, J., Refsgaard, L., Haunsø, Stig, Olesen, Søren-Peter, Nielsen, J. B., Schmitt, Nicole & Svendsen, Jesper Hastrup, Feb 2014, In: Heart Rhythm. 11, 2, p. 246-251 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Verification of threshold for image intensity ratio analyses of late gadolinium enhancement magnetic resonance imaging of left atrial fibrosis in 1.5T scans

    Bertelsen, L., Alarcón, F., Andreasen, Laura Korsholm, Benito, E., Olesen, Morten Steen Salling, Vejlstrup, N., Mont, L. & Svendsen, Jesper Hastrup, 2020, In: International Journal of Cardiovascular Imaging. 36, p. 513–520 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. E-pub ahead of print

    Unlocking the Genetic Code: Novel Insights Into Familial Atrial Fibrillation and Gene-Variant Interactions

    Vad, Oliver Tim Bundgaard & Olesen, Morten Steen Salling, 2024, (E-pub ahead of print) In: Canadian Journal of Cardiology.

    Research output: Contribution to journalEditorialResearchpeer-review

  7. Published

    Transethnic Genome-Wide Association Study Provides Insights in the Genetic Architecture and Heritability of Long QT Syndrome

    Lahrouchi, N., Tadros, R., Crotti, L., Mizusawa, Y., Postema, P. G., Beekman, L., Walsh, R., Hasegawa, K., Barc, J., Ernsting, M., Turkowski, K. L., Mazzanti, A., Beckmann, B. M., Shimamoto, K., Diamant, U-B., Wijeyeratne, Y. D., Kucho, Y., Robyns, T., Ishikawa, T., Arbelo, E. & 86 others, Christiansen, M., Winbo, A., Jabbari, R., Lubitz, S. A., Steinfurt, J., Rudic, B., Loeys, B., Shoemaker, M. B., Weeke, P. E., Pfeiffer, R., Davies, B., Andorin, A., Hofman, N., Dagradi, F., Pedrazzini, M., Tester, D. J., Bos, J. M., Sarquella-Brugada, G., Campuzano, Ó., Platonov, P. G., Stallmeyer, B., Zumhagen, S., Nannenberg, E. A., Veldink, J. H., van den Berg, L. H., Al-Chalabi, A., Shaw, C. E., Shaw, P. J., Morrison, K. E., Andersen, P. M., Müller-Nurasyid, M., Cusi, D., Barlassina, C., Galan, P., Lathrop, M., Munter, M., Werge, Thomas, Ribasés, M., Aung, T., Khor, C. C., Ozaki, M., Lichtner, P., Meitinger, T., van Tintelen, J. P., Hoedemaekers, Y., Denjoy, I., Leenhardt, A., Napolitano, C., Shimizu, W., Schott, J., Gourraud, J., Makiyama, T., Ohno, S., Itoh, H., Krahn, A. D., Antzelevitch, C., Roden, D. M., Saenen, J., Borggrefe, M., Odening, K. E., Ellinor, P. T., Tfelt-Hansen, Jacob, Skinner, J. R., van den Berg, M. P., Olesen, Morten Steen Salling, Brugada, J., Brugada, R., Makita, N., Breckpot, J., Yoshinaga, M., Behr, E. R., Rydberg, A., Aiba, T., Kääb, S., Priori, S. G., Guicheney, P., Tan, H. L., Newton-Cheh, C., Ackerman, M. J., Schwartz, P. J., Schulze-Bahr, E., Probst, V., Horie, M., Wilde, A. A., Tanck, M. W. T. & Bezzina, C. R., 2020, In: Circulation. 142, 4, p. 324-338

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    The two-pore domain potassium channel, TWIK-1, has a role in the regulation of heart rate and atrial size

    Christensen, A. H., Chatelain, F. C., Huttner, I. G., Olesen, Morten Steen Salling, Soka, M., Feliciangeli, S., Horvat, C., Santiago, C. F., Vandenberg, J. I., Schmitt, Nicole, Olesen, Søren-Peter, Lesage, F. & Fatkin, D., Aug 2016, In: Journal of Molecular and Cellular Cardiology. 97, p. 24-35 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    The role of the sodium current complex in a nonreferred nationwide cohort of sudden infant death syndrome

    Winkel, B. G., Yuan, L., Olesen, Morten Steen Salling, Sadjadieh, G., Wang, Y., Risgaard, B., Jabbari, R., Haunsø, Stig, Holst, A. G., Hollegaard, M. V., Tfelt-Hansen, J. & Jespersen, Thomas, Jun 2015, In: Heart rhythm : the official journal of the Heart Rhythm Society. 12, 6, p. 1241-1249 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    The role of common genetic variants in atrial fibrillation

    Paludan-Müller, Christian, Svendsen, Jesper Hastrup & Olesen, Morten Steen Salling, 2016, In: Journal of Electrocardiology. 49, 6, p. 864-870

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    The genetic component of Brugada syndrome

    Nielsen, M. W., Holst, A. G., Olesen, Søren-Peter & Olesen, Morten Steen Salling, 2013, In: Frontiers in Physiology. 4, p. 179

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    The genetic component of Brugada syndrome

    Nielsen, M. W., Holst, A. G., Olesen, Søren-Peter & Olesen, Morten Steen Salling, 2013, In: Frontiers in Physiology. 4, p. 179

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    The Novel Desmin Mutant p.A120D Impairs Filament Formation, Prevents Intercalated Disk Localization, and Causes Sudden Cardiac Death

    Brodehl, A., Dieding, M., Klauke, B., Dec, E., Madaan, S., Huang, T., Gargus, J., Fatima, A., Saric, T., Cakar, H., Walhorn, V., Tönsing, K., Skrzipczyk, T., Cebulla, R., Gerdes, D., Schulz, U., Gummert, J., Svendsen, J. H., Olesen, M. S. S., Anselmetti, D. & 3 others, Christensen, Alex Hørby, Kimonis, V. & Milting, H., 2013, In: Circulation. Cardiovascular Genetics (Online). 6, 6, p. 615-623 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    The ABC-Stroke Risk Score and Effects of Atrial Fibrillation Screening on Stroke Prevention: Results From the Randomized LOOP Study

    Xing, L. Y., Diederichsen, S. Z., Højberg, S., Krieger, D. W., Graff, C., Frikke-Schmidt, Ruth, Platonov, P. G., Olesen, Morten Steen Salling, Brandes, A., Køber, Lars Valeur, Haugan, K. J. & Svendsen, Jesper Hastrup, 2024, In: Journal of the American Heart Association. 13, 4, 12 p., e032744.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Tackling a growing healthcare challenge: atrial fibrillation epidemiology, prevention, and underlying causes

    Vad, Oliver Tim Bundgaard, Paludan-Müller, Christian, Diederichsen, S. Z. & Olesen, Morten Steen Salling, 2024, In: The Lancet Regional Health - Europe. 37, 2 p., 100827.

    Research output: Contribution to journalComment/debateResearchpeer-review

  16. Published

    Severity and Etiology of Incident Stroke in Patients Screened for Atrial Fibrillation vs Usual Care and the Impact of Prior Stroke: A Post Hoc Analysis of the LOOP Randomized Clinical Trial

    Diederichsen, S. Z., Frederiksen, K. S., Xing, L. Y., Haugan, K. J., Højberg, S., Brandes, A., Graff, C., Olesen, Morten Steen Salling, Krieger, D., Køber, Lars Valeur & Svendsen, Jesper Hastrup, 2022, In: JAMA Neurology. 79, 10, p. 997-1004

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Screening of the Ito regulatory subunit Klf15 in patients with early-onset lone atrial fibrillation

    Nielsen, M. W., Olesen, Morten Steen Salling, Refsgaard, L., Haunsø, Stig & Svendsen, Jesper Hastrup, 2013, In: Frontiers in Genetics. 4, p. 1-2 2 p., 88.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Screening for atrial fibrillation to prevent stroke in elderly individuals with or without preexisting cardiovascular disease: A post hoc analysis of the randomized LOOP Study

    Xing, L. Y., Diederichsen, S. Z., Højberg, S., Krieger, D. W., Graff, C., Olesen, Morten Steen Salling, Brandes, A., Køber, Lars Valeur, Haugan, K. J. & Svendsen, Jesper Hastrup, 2023, In: International Journal of Cardiology. 370, p. 197-203 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Role of common and rare variants in SCN10A: results from the Brugada syndrome QRS locus gene discovery collaborative study

    Behr, E. R., Savio-Galimberti, E., Barc, J., Holst, A. G., Petropoulou, E., Prins, B. P., Jabbari, J., Torchio, M., Berthet, M., Mizusawa, Y., Yang, T., Nannenberg, E. A., Dagradi, F., Weeke, P., Bastiaenan, R., Ackerman, M. J., Haunso, S., Leenhardt, A., Kääb, S., Probst, V. & 13 others, Redon, R., Sharma, S., Wilde, A., Tfelt-Hansen, J., Schwartz, P., Roden, D. M., Bezzina, C. R., Olesen, Morten Steen Salling, Darbar, D., Guicheney, P., Crotti, L., UK10K Consortium, U. C. & Jamshidi, Y., 1 Jun 2015, In: Cardiovascular Research. 106, 3, p. 520-529 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Risk prediction of cardiovascular death based on the QTc interval: evaluating age and gender differences in a large primary care population

    Nielsen, J. B., Graff, C., Rasmussen, P. V., Pietersen, A., Lind, B., Olesen, Morten Steen Salling, Struijk, J. J., Haunsø, Stig, Svendsen, Jesper Hastrup, Køber, Lars Valeur, Gerds, Thomas Alexander & Holst, A. G., 2014, In: European Heart Journal. 35, 20, p. 1335-44 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Risk of atrial fibrillation as a function of the electrocardiographic PR interval: Results from the Copenhagen ECG Study

    Nielsen, J. B., Pietersen, A., Graff, C., Lind, B., Struijk, J. J., Olesen, Morten Steen Salling, Haunsø, Stig, Gerds, Thomas Alexander, Ellinor, P. T., Køber, Lars Valeur, Svendsen, Jesper Hastrup & Holst, A. G., 2013, In: Heart rhythm : the official journal of the Heart Rhythm Society. 10, 9, p. 1249-1256 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Risk Prediction of Atrial Fibrillation Based on Electrocardiographic Interatrial Block

    Skov, M. W., Ghouse, J., Kühl, J. T., Platonov, P. G., Graff, C., Fuchs, A., Rasmussen, P. V., Pietersen, A., Nordestgaard, Børge, Torp-Pedersen, C., Hansen, S. M., Olesen, Morten Steen Salling, Haunsø, Stig, Køber, Lars Valeur, Gerds, Thomas Alexander, Kofoed, Klaus Fuglsang, Svendsen, Jesper Hastrup, Holst, A. G. & Nielsen, J. B., 5 Jun 2018, In: Journal of the American Heart Association. 7, 11, 19 p., e008247.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Reevaluation of genetic variants previously associated with arrhythmogenic right ventricular cardiomyopathy integrating population-based cohorts and proteomics data

    Ye, J. Z., Delmar, M., Lundby, Alicia & Olesen, Morten Steen Salling, 2019, In: Clinical Genetics. 96, 6, p. 506-514

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Reappraisal of variants previously linked with sudden infant death syndrome: results from three population-based cohorts

    Paludan-Müller, Christian, Ghouse, Jonas, Vad, O. B., Herfelt, C. B., Lundegaard, Pia Rengtved, Ahlberg, G., Schmitt, Nicole, Svendsen, Jesper Hastrup, Haunsø, Stig, Bundgård, Henning, Hansen, Torben, Kanters, Jørgen K. & Olesen, Morten Steen Salling, 2019, In: European Journal of Human Genetics. 27, 9, p. 1427-1435

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Rare variants in HCN4 identified in the general population are associated with complete atrioventricular (AV) block, 1. degree AV block and bundle branch block, results from 50.000 exomes

    Jensen, J. S., Vad, O. B., Paludan-Mueller, C., Lundegaard, Pia Rengtved, Svendsen, Jesper Hastrup, Haunsø, Stig, Bundgård, Henning & Olesen, Morten Steen Salling, 2020, In: European Journal of Human Genetics. 28, SUPPL 1, p. 271-272 P05.47.B.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  26. Published

    Rare truncating variants in the sarcomeric protein titin associate with familial and early-onset atrial fibrillation

    Ahlberg, G., Refsgaard, L., Lundegaard, Pia Rengtved, Andreasen, Laura Korsholm, Ranthe, M. F., Linscheid, N., Nielsen, J. B., Melbye, M., Haunsø, Stig, Sajadieh, Ahmad, Camp, L., Olesen, Søren-Peter, Rasmussen, Simon, Lundby, Alicia, Ellinor, P. T., Holst, A. G., Svendsen, Jesper Hastrup & Olesen, Morten Steen Salling, 2018, In: Nature Communications. 9, 1, 11 p., 4316.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Rare coding variants in MYH6 are associated with atrial fibrillation: results from 45,596 exomes representing the general population

    Vad, O. B., Paludan-Muller, C., Ahlberg, G., Andreasen, L., Refsgaard, L., Lundegaard, Pia Rengtved, Haunsø, Stig, Svendsen, Jesper Hastrup & Olesen, Morten Steen Salling, 2020, In: European Heart Journal. 41, p. 342-342

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  28. Published

    Rare Variants in GJA5 Are Associated With Early-Onset Lone Atrial Fibrillation

    Christophersen, I. E., Holmegard, H. N., Jabbari, J., Sajadieh, Ahmad, Haunsø, Stig, Tveit, A., Svendsen, Jesper Hastrup & Olesen, Morten Steen Salling, 2013, In: Canadian Journal of Cardiology. 29, 1, p. 111-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Quantitative proteomics of human heart samples collected In vivo reveal the remodeled protein landscape of dilated left atrium without atrial fibrillation

    Linscheid, N., Poulsen, P. C., Pedersen, I. D., Gregers, E., Svendsen, Jesper Hastrup, Olesen, Morten Steen Salling, Olsen, Jesper Velgaard, Delmar, M. & Lundby, Alicia, 2020, In: Molecular and Cellular Proteomics. 19, 7, p. 1132-1144

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Quantitative proteome comparison of human hearts with those of model organisms

    Linscheid, N., Santos, A., Poulsen, P. C., Mills, Robert William, Callø, Kirstine, Leurs, U., Ye, J. Z., Stolte, C., Thomsen, Morten Bækgaard, Bentzen, Bo Hjorth, Lundegaard, Pia Rengtved, Olesen, Morten Steen Salling, Jensen, Lars Juhl, Olsen, Jesper Velgaard & Lundby, Alicia, 2021, In: PLOS Biology. 19, 4, 22 p., e3001144.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. E-pub ahead of print

    Proteomics couples electrical remodelling to inflammation in a murine model of heart failure with sinus node dysfunction

    Kahnert, K., Soattin, L., Mills, R. W., Wilson, C., Maurya, S., Sorrentino, A., Al-Othman, S., Tikhomirov, R., van de Vegte, Y. J., Hansen, F. B., Achter, J., Hu, W., Zi, M., Smith, M., van der Harst, P., Olesen, M. S., Olsen, K. B., Banner, J., Jensen, T. H. L., Zhang, H. & 3 others, Boyett, M. R., D'Souza, A. & Lundby, Alicia, 2024, (E-pub ahead of print) In: Cardiovascular Research. cvae054.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Presence of Atrioventricular Nodal Reentrant Tachycardia Is Associated With Cardiomyopathy, Heart Failure, and Death

    Paludan-Müller, Christian, Stampe, N. K., Monfort, L. M., Andreasen, L., Vad, Oliver Tim Bundgaard, Ahlberg, Gustav, Johansen, J. B., Winkel, B. G., Torp-Pedersen, Christian, Køber, Lars Valeur, Fosbøl, Emil Loldrup, Svendsen, Jesper Hastrup & Olesen, Morten Steen Salling, 2024, In: Journal of the American Heart Association. 13, 9, 4 p., e034439.

    Research output: Contribution to journalLetterResearchpeer-review

  33. Published

    Potential Influence of Risk Factor Control on the Association between Lipoprotein(a) and Atherosclerotic Cardiovascular Disease

    Ghouse, Jonas, Ahlberg, G., Rand, S. A., Olesen, Morten Steen Salling, Vilhjalmsson, B., Stender, Stefan & Bundgård, Henning, 2024, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 44, 6, p. 1455-1457

    Research output: Contribution to journalLetterResearchpeer-review

  34. Published

    Polygenic risk score for ACE-inhibitor-associated cough based on the discovery of new genetic loci

    Ghouse, J., Tragante, V., Muhammad, A., Ahlberg, G., Skov, M. W., Roden, D. M., Jonsdottir, I., Andreasen, L., Lundegaard, P. R., Trudsø, L. C., Banasik, K., Brunak, S., Ostrowski, S. R., Torp-Pedersen, C., Pedersen, O. V., Sørensen, E., Køber, L., Iversen, K., Thorsteinsdottir, U., Thorgeirsson, G. & 8 others, Ullum, H., Gudbjartsson, D. F., Mosley, J. D., Holm, H., Stefansson, K., Bundgård, Henning, Olesen, Morten Steen Salling & eMERGE consortium, E. C., 2022, In: European Heart Journal. 43, 45, p. 4707–4718

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Obesity Partially Mediates the Diabetogenic Effect of Lowering LDL Cholesterol

    Wu, P., Moon, J-Y., Daghlas, I., Franco, G., Porneala, B. C., Ahmadizar, F., Richardson, T. G., Isaksen, J. L., Hindy, G., Yao, J., Sitlani, C. M., Raffield, L. M., Yanek, L. R., Feitosa, M. F., Cuadrat, R. R. C., Qi, Q., Arfan Ikram, M., Ellervik, C., Ericson, U., Goodarzi, M. O. & 30 others, Brody, J. A., Lange, L., Mercader, J. M., Vaidya, D., An, P., Schulze, M. B., Masana, L., Ghanbari, M., Olesen, Morten Steen Salling, Cai, J., Guo, X., Floyd, J. S., Jäger, S., Province, M. A., Kalyani, R. R., Psaty, B. M., Orho-Melander, M., Ridker, P. M., Kanters, Jørgen K., Uitterlinden, A., Davey Smith, G., Gill, D., Kaplan, R. C., Kavousi, M., Raghavan, S., Chasman, D. I., Rotter, J. I., Meigs, J. B., Florez, J. C. & Dupuis, J., 2021, In: Diabetes Care. 45, 1, p. 232–240

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published
  37. Published

    Next-generation sequencing of AV nodal reentrant tachycardia patients identifies broad spectrum of variants in ion channel genes

    Andreasen, Laura Korsholm, Ahlberg, G., Tang, C., Andreasen, C., Hartmann, J. P., Tfelt-Hansen, Jacob, Behr, E. R., Pehrson, S., Haunsø, Stig, LuCamp, Weeke, P. E., Jespersen, Thomas, Olesen, Morten Steen Salling & Svendsen, Jesper Hastrup, 2018, In: European Journal of Human Genetics. 26, p. 660–668

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    New population-based exome data question the pathogenicity of some genetic variants previously associated with Marfan syndrome

    Yang, R., Jabbari, J., Cheng, X., Jabbari, R., Nielsen, J. B., Risgaard, B., Chen, X., Sajadieh, Ahmad, Haunsø, Stig, Svendsen, Jesper Hastrup, Olesen, Morten Steen Salling & Tfelt-Hansen, J., 2014, In: B M C Genetics. 15, p. 1-8 8 p., 74.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    New population-based exome data are questioning the pathogenicity of previously cardiomyopathy-associated genetic variants

    Andreasen, C. H., Nielsen, J. B., Refsgaard, L., Holst, A. G., Christensen, Alex Hørby, Andreasen, Laura Korsholm, Sajadieh, Ahmad, Haunsø, Stig, Svendsen, Jesper Hastrup & Olesen, Morten Steen Salling, 2013, In: European Journal of Human Genetics. 21, 9, p. 918-928 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    New exome data question the pathogenicity of genetic variants previously associated with catecholaminergic polymorphic ventricular tachycardia

    Jabbari, J., Jabbari, R., Nielsen, M. W., Holst, A. G., Nielsen, J. B., Haunsø, Stig, Tfelt-Hansen, J., Svendsen, Jesper Hastrup & Olesen, Morten Steen Salling, 2013, In: Circulation. Cardiovascular Genetics (Online). 6, 5, p. 481-489 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Natural History and Clinical Characteristics of the First 10 Danish Families With Familial ST-Depression Syndrome

    Christensen, A. H., Nyholm, B. C., Vissing, C. R., Pietersen, A., Tfelt-Hansen, Jacob, Olesen, Morten Steen Salling, Pehrson, S., Iversen, Kasper, Jensen, H. K. & Bundgård, Henning, 2021, In: Journal of the American College of Cardiology. 77, 20, p. 2617-2619

    Research output: Contribution to journalLetterResearchpeer-review

  42. Published

    Nationwide (Denmark) Study of Symptoms Preceding Sudden Death due to Arrhythmogenic Right Ventricular Cardiomyopathy

    Sadjadieh, G., Jabbari, R., Risgaard, B., Olesen, Morten Steen Salling, Haunsø, Stig, Tfelt-Hansen, J. & Winkel, B. G., 1 Apr 2014, In: American Journal of Cardiology. 113, 7, p. 1250-1254 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Mutations in Genes Encoding Cardiac Ion Channels Previously Associated With Sudden Infant Death Syndrome (SIDS) Are Present With High Frequency in New Exome Data

    Andreasen, C. H., Refsgaard, L., Nielsen, J. B., Sajadieh, Ahmad, Winkel, B. G., Tfelt-Hansen, J., Haunsø, Stig, Holst, A. G., Svendsen, Jesper Hastrup & Olesen, Morten Steen Salling, 2013, In: Canadian Journal of Cardiology. 29, 9, p. 1104-1109 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Mutation analysis of the candidate genes -, , and in patients with arrhythmogenic right ventricular cardiomyopathy

    Refsgaard, L., Olesen, Morten Steen Salling, Møller, D. V., Christiansen, M., Haunsø, Stig, Svendsen, Jesper Hastrup & Christensen, Alex Hørby, 1 Dec 2012, In: Applied and Translational Genomics. 1, p. 44-46

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Multifocal atrial and ventricular premature contractions with an increased risk of dilated cardiomyopathy caused by a Nav1.5 gain-of-function mutation (G213D)

    Callø, Kirstine, Broendberg, A. K., Christensen, A. H., Pedersen, L. N., Olesen, Morten Steen Salling, de Los Angeles Tejada, M., Friis, S., Thomsen, Morten Bækgaard, Bundgård, Henning & Jensen, H. K., 15 Apr 2018, In: International Journal of Cardiology. 257, p. 160-167 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications

    Sterenborg, R. B. T. M., Steinbrenner, I., Li, Y., Bujnis, M. N., Naito, T., Marouli, E., Galesloot, T. E., Babajide, O., Andreasen, L., Astrup, A., Åsvold, B. O., Bandinelli, S., Beekman, M., Beilby, J. P., Bork-Jensen, J., Boutin, T., Brody, J. A., Brown, S. J., Brumpton, B., Campbell, P. J. & 121 others, Cappola, A. R., Ceresini, G., Chaker, L., Chasman, D. I., Concas, M. P., Coutinho de Almeida, R., Cross, S. M., Cucca, F., Deary, I. J., Kjaergaard, A. D., Echouffo Tcheugui, J. B., Ellervik, Christina, Eriksson, J. G., Ferrucci, L., Freudenberg, J., Fuchsberger, C., Gieger, C., Giulianini, F., Gögele, M., Graham, S. E., Grarup, Niels, Gunjača, I., Hansen, Torben, Harding, B. N., Harris, S. E., Haunsø, Stig, Hayward, C., Hui, J., Ittermann, T., Jukema, J. W., Kajantie, E., Kanters, Jørgen K., Kårhus, L. L., Kiemeney, L. A. L. M., Kloppenburg, M., Kühnel, B., Lahti, J., Langenberg, C., Lapauw, B., Leese, G., Li, S., Liewald, D. C. M., Linneberg, Allan René, Lominchar, J. V. T., Luan, J., Martin, N. G., Matana, A., Meima, M. E., Meitinger, T., Meulenbelt, I., Mitchell, B. D., Møllehave, L. T., Mora, S., Naitza, S., Nauck, M., Netea-Maier, R. T., Noordam, R., Nursyifa, Casia, Okada, Y., Onano, S., Papadopoulou, A., Palmer, C. N. A., Pattaro, C., Pedersen, Oluf Borbye, Peters, A., Pietzner, M., Polašek, O., Pramstaller, P. P., Psaty, B. M., Punda, A., Ray, D., Redmond, P., Richards, J. B., Ridker, P. M., Russ, T. C., Ryan, K. A., Olesen, Morten Steen Salling, Schultheiss, U. T., Selvin, E., Siddiqui, M. K., Sidore, C., Slagboom, P. E., Sørensen, Thorkild I.A., Soto-Pedre, E., Spector, T. D., Spedicati, B., Srinivasan, S., Starr, J. M., Stott, D. J., Tanaka, T., Torlak, V., Trompet, S., Tuhkanen, J., Uitterlinden, A. G., van den Akker, E. B., van den Eynde, T., van der Klauw, M. M., van Heemst, D., Verroken, C., Visser, W. E., Vojinovic, D., Völzke, H., Waldenberger, M., Walsh, J. P., Wareham, N. J., Weiss, S., Willer, C. J., Wilson, S. G., Wolffenbuttel, B. H. R., Wouters, H. J. C. M., Wright, M. J., Yang, Q., Zemunik, T., Zhou, W., Zhu, G., Zöllner, S., Smit, J. W. A., Peeters, R. P., Köttgen, A., Teumer, A. & Medici, M., 2024, In: Nature Communications. 15, 1, 18 p., 888.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Multi-ethnic genome-wide association study for atrial fibrillation

    Roselli, C., Chaffin, M. D., Weng, L-C., Aeschbacher, S., Ahlberg, G., Albert, C. M., Almgren, P., Alonso, A., Anderson, C. D., Aragam, K. G., Arking, D. E., Barnard, J., Bartz, T. M., Benjamin, E. J., Bihlmeyer, N. A., Bis, J. C., Bloom, H. L., Boerwinkle, E., Bottinger, E. B., Brody, J. A. & 34 others, Calkins, H., Campbell, A., Cappola, T. P., Carlquist, J., Chasman, D. I., Chen, L. Y., Chen, Y. I., Choi, E., Choi, S. H., Christophersen, I. E., Chung, M. K., Cole, J. W., Conen, D., Cook, J., Crijns, H. J., Cutler, M. J., Damrauer, S. M., Daniels, B. R., Darbar, D., Delgado, G., Denny, J. C., Dichgans, M., Doerr, M., Dudink, E. A., Lind, L., Loos, Ruth, Olesen, Morten Steen Salling, Refsgaard, L., Svendsen, Jesper Hastrup, Weeke, P. E., et al., E. A., Lubitz, S. A., Lunetta, K. L. & Ellinor, P. T., Sep 2018, In: Nature Genetics. 50, 9, p. 1225-1233

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction

    Ntalla, I., Weng, L. C., Cartwright, J. H., Hall, A. W., Sveinbjornsson, G., Tucker, N. R., Choi, S. H., Chaffin, M. D., Roselli, C., Barnes, M. R., Mifsud, B., Warren, H. R., Hayward, C., Marten, J., Cranley, J. J., Concas, M. P., Gasparini, P., Boutin, T., Kolcic, I., Polasek, O. & 167 others, Rudan, I., Araujo, N. M., Lima-Costa, M. F., Ribeiro, A. L. P., Souza, R. P., Tarazona-Santos, E., Giedraitis, V., Ingelsson, E., Mahajan, A., Morris, A. P., Del Greco M, F., Foco, L., Gögele, M., Hicks, A. A., Cook, J. P., Lind, L., Lindgren, C. M., Sundström, J., Nelson, C. P., Riaz, M. B., Samani, N. J., Sinagra, G., Ulivi, S., Kähönen, M., Mishra, P. P., Mononen, N., Nikus, K., Caulfield, M. J., Dominiczak, A., Padmanabhan, S., Montasser, M. E., O’Connell, J. R., Ryan, K., Shuldiner, A. R., Aeschbacher, S., Conen, D., Risch, L., Thériault, S., Hutri-Kähönen, N., Lehtimäki, T., Lyytikäinen, L. P., Raitakari, O. T., Barnes, C. L. K., Campbell, H., Joshi, P. K., Wilson, J. F., Isaacs, A., Kors, J. A., van Duijn, C. M., Huang, P. L., Gudnason, V., Harris, T. B., Launer, L. J., Smith, A. V., Bottinger, E. P., Loos, Ruth, Nadkarni, G. N., Preuss, M. H., Correa, A., Mei, H., Wilson, J., Meitinger, T., Müller-Nurasyid, M., Peters, A., Waldenberger, M., Mangino, M., Spector, T. D., Rienstra, M., van de Vegte, Y. J., van der Harst, P., Verweij, N., Kääb, S., Schramm, K., Sinner, M. F., Strauch, K., Cutler, M. J., Fatkin, D., London, B., Olesen, Morten Steen Salling, Roden, D. M., Benjamin Shoemaker, M., Gustav Smith, J., Biggs, M. L., Bis, J. C., Brody, J. A., Psaty, B. M., Rice, K., Sotoodehnia, N., De Grandi, A., Fuchsberger, C., Pattaro, C., Pramstaller, P. P., Ford, I., Wouter Jukema, J., Macfarlane, P. W., Trompet, S., Dörr, M., Felix, S. B., Völker, U., Weiss, S., Havulinna, A. S., Jula, A., Sääksjärvi, K., Salomaa, V., Guo, X., Heckbert, S. R., Lin, H. J., Rotter, J. I., Taylor, K. D., Yao, J., de Mutsert, R., Maan, A. C., Mook-Kanamori, D. O., Noordam, R., Cucca, F., Ding, J., Lakatta, E. G., Qian, Y., Tarasov, K. V., Levy, D., Lin, H., Newton-Cheh, C. H., Lunetta, K. L., Murray, A. D., Porteous, D. J., Smith, B. H., Stricker, B. H., Uitterlinden, A., van den Berg, M. E., Haessler, J., Jackson, R. D., Kooperberg, C., Peters, U., Reiner, A. P., Whitsel, E. A., Alonso, A., Arking, D. E., Boerwinkle, E., Ehret, G. B., Soliman, E. Z., Avery, C. L., Gogarten, S. M., Kerr, K. F., Laurie, C. C., Seyerle, A. A., Stilp, A., Assa, S., Abdullah Said, M., Yldau van der Ende, M., Lambiase, P. D., Orini, M., Ramirez, J., Van Duijvenboden, S., Arnar, D. O., Gudbjartsson, D. F., Holm, H., Sulem, P., Thorleifsson, G., Thorolfsdottir, R. B., Thorsteinsdottir, U., Benjamin, E. J., Tinker, A., Stefansson, K., Ellinor, P. T., Jamshidi, Y., Lubitz, S. A. & Munroe, P. B., 1 Dec 2020, In: Nature Communications. 11, 1, 2542.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Loss-of-function genomic variants highlight potential therapeutic targets for cardiovascular disease

    Nielsen, J. B., Rom, O., Surakka, I., Graham, S. E., Zhou, W., Roychowdhury, T., Fritsche, L. G., Taliun, S. A. G., Sidore, C., Liu, Y., Gabrielsen, M. E., Skogholt, A. H., Wolford, B., Overton, W., Zhao, Y., Chen, J., Zhang, H., Hornsby, W. E., Acheampong, A., Grooms, A. & 30 others, Schaefer, A., Zajac, G. J. M., Villacorta, L., Zhang, J., Brumpton, B., Loset, M., Rai, V., Lundegaard, Pia Rengtved, Olesen, Morten Steen Salling, Taylor, K. D., Palmer, N. D., Chen, Y., Choi, S. H., Lubitz, S. A., Ellinor, P. T., Barnes, K. C., Daya, M., Rafaels, N., Weiss, S. T., Lasky-Su, J., Tracy, R. P., Vasan, R. S., Cupples, L. A., Mathias, R. A., Yanek, L. R., Becker, L. C., Peyser, P. A., Bielak, L. F., Smith, J. A. & Aslibekyan, S., 2020, In: Nature Communications. 11, 1, 12 p., 6417.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Loss-of-Function Variants in the SYNPO2L Gene Are Associated With Atrial Fibrillation

    Clausen, A. G., Vad, O. B., Andersen, J. H. & Olesen, Morten Steen Salling, 2021, In: Frontiers in Cardiovascular Medicine. 8, 9 p., 650667.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Loss-of-Function Variants in Cytoskeletal Genes Are Associated with Early-Onset Atrial Fibrillation

    Vad, O. B., Paludan-Müller, Christian, Ahlberg, G., Kalsto, S. M., Ghouse, Jonas, Andreasen, Laura Korsholm, Haunsø, Stig, Tveit, A., Sajadieh, Ahmad, Christophersen, I. E., Svendsen, Jesper Hastrup & Olesen, Morten Steen Salling, 2020, In: Journal of Clinical Medicine. 9, 2, 12 p., 372.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Loss of Cardiac Splicing Regulator RBM20 Is Associated With Early-Onset Atrial Fibrillation

    Vad, Oliver Tim Bundgaard, Angeli, Elisavet, Liss, M., Ahlberg, Gustav, Andreasen, Laura Korsholm, Christophersen, I. E., Hansen, Camilla Collin, Møller, S., Hellsten, Ylva, Haunsø, Stig, Tveit, A., Svendsen, Jesper Hastrup, Gotthardt, M., Lundegaard, Pia Rengtved & Olesen, Morten Steen Salling, 2024, In: JACC: Basic to Translational Science. 9, 2, p. 163-180

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Left Atrial Remodeling and Cerebrovascular Disease Assessed by Magnetic Resonance Imaging in Continuously Monitored Patients

    Bertelsen, L., Diederichsen, S. Z., Frederiksen, K. S., Haugan, K. J., Brandes, A., Graff, C., Krieger, D., Højberg, S., Olesen, Morten Steen Salling, Biering-Sørensen, Tor, Køber, Lars Valeur, Vejlstrup, N., Hasselbalch, Steen & Svendsen, Jesper Hastrup, 2022, In: Cerebrovascular Diseases. 51, 3, p. 403–412

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Left Atrial Late Gadolinium Enhancement is Associated With Incident Atrial Fibrillation as Detected by Continuous Monitoring With Implantable Loop Recorders

    Bertelsen, L., Diederichsen, S. Z., Haugan, K. J., Brandes, A., Graff, C., Krieger, D., Kronborg, C., Køber, Lars Valeur, Peters, D. C., Olesen, Morten Steen Salling, Højberg, S., Vejlstrup, N. & Svendsen, Jesper Hastrup, 2020, In: JACC. Cardiovascular imaging. 13, 8, p. 1690-1700 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    KCNE1 G38S polymorphism is not the cause of long QT syndrome

    Kanters, Jørgen K., Olesen, Morten Steen Salling & Christiansen, M., 20 Jan 2016, In: Journal of Electrocardiology. 49, 2, p. 249-50 2 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  56. Published

    J-shaped association between QTc interval duration and the risk of atrial fibrillation: Results From the Copenhagen ECG Study

    Nielsen, J. B., Graff, C., Pietersen, A., Lind, B., Struijk, J. J., Olesen, Morten Steen Salling, Haunsø, Stig, Gerds, Thomas Alexander, Svendsen, Jesper Hastrup, Køber, Lars Valeur & Holst, A. G., 2013, In: Journal of the American College of Cardiology. 61, 25, p. 2557-2564 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Investigations of the Navβ1b sodium channel subunit in human ventricle; functional characterization of the H162P Brugada Syndrome mutant

    Yuan, L., Koivumaki, J., Liang, B., Lorentzen, L. G., Tang, C., Andersen, M. N., Svendsen, Jesper Hastrup, Tfelt-Hansen, J., Maleckar, M., Schmitt, Nicole, Olesen, Morten Steen Salling & Jespersen, Thomas, 21 Feb 2014, In: American Journal of Physiology: Heart and Circulatory Physiology. 306, 8, p. H1204-12

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Investigating gene-microRNA networks in atrial fibrillation patients with mitral valve regurgitation

    Santos, J. L., Rodríguez, I., Olesen, Morten Steen Salling, Bentzen, Bo Hjorth & Schmitt, Nicole, 2020, In: PLoS ONE. 15, 5, 21 p., e0232719.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Integrative common and rare variant analyses provide insights into the genetic architecture of liver cirrhosis

    Ghouse, J., Sveinbjörnsson, G., Vujkovic, M., Seidelin, A-S., Gellert-Kristensen, H., Ahlberg, G., Tragante, V., Rand, S. A., Brancale, J., Vilarinho, S., Lundegaard, P. R., Sørensen, E., Erikstrup, C., Bruun, M. T., Jensen, B. A., Brunak, S., Banasik, K., Ullum, H., Verweij, N., Lotta, L. & 31 others, Baras, A., Mirshahi, T., Carey, D. J., Kaplan, D. E., Lynch, J., Morgan, T., Schwantes-An, T., Dochtermann, D. R., Pyarajan, S., Tsao, P. S., Laisk, T., Mägi, R., Kozlitina, J., Tybjærg-Hansen, Anne, Jones, D., Knowlton, K. U., Nadauld, L., Ferkingstad, E., Björnsson, E. S., Ulfarsson, M. O., Sturluson, Á., Sulem, P., Pedersen, Ole Birger Vesterager, Ostrowski, Sisse Rye, Gudbjartsson, D. F., Stefansson, K., Olesen, Morten Steen Salling, Chang, K., Bundgård, Henning, Stender, Stefan & DBDS Genomic Consortium, D. G. C., 2024, In: Nature Genetics. 56, p. 827–837 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Integration of Scandinavian genetic data with UK biobank data implicates the RBM20 gene with atrial fibrillation pathogenesis

    Vad, O. B., Angeli, Elisavet, Liss, M., Ahlberg, G., Andreasen, L., Christophersen, I. E., Tveit, A., Haunsø, Stig, Svendsen, Jesper Hastrup, Lundegaard, Pia Rengtved, Gotthardt, M. & Olesen, Morten Steen Salling, 2021, In: European Heart Journal. 42, p. 3319-3319 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

  61. Published
  62. Published

    Integrating genetic, transcriptional, and functional analyses to identify 5 novel genes for atrial fibrillation

    Sinner, M. F., Tucker, N. R., Lunetta, K. L., Ozaki, K., Smith, J. G., Trompet, S., Bis, J. C., Lin, H., Chung, M. K., Nielsen, J. B., Lubitz, S. A., Krijthe, B. P., Magnani, J. W., Ye, J., Gollob, M. H., Tsunoda, T., Müller-Nurasyid, M., Lichtner, P., Peters, A., Dolmatova, E. & 31 others, Kubo, M., Smith, J. D., Psaty, B. M., Smith, N. L., Jukema, J. W., Chasman, D. I., Albert, C. M., Ebana, Y., Furukawa, T., Macfarlane, P. W., Harris, T. B., Darbar, D., Dörr, M., Holst, A. G., Svendsen, Jesper Hastrup, Hofman, A., Uitterlinden, A. G., Gudnason, V., Isobe, M., Malik, R., Dichgans, M., Rosand, J., Van Wagoner, D. R., Benjamin, E. J., Milan, D. J., Melander, O., Heckbert, S. R., Ford, I., Liu, Y., Olesen, Morten Steen Salling & METASTROKE Consortium, M. C., 2014, In: Circulation. 130, 15, p. 1225-1235 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Insights into the genome-wide association studies of the electrocardiographic early repolarization pattern

    Risgaard, B., Olesen, Morten Steen Salling & Tfelt-Hansen, J., Oct 2012, In: Heart Rhythm. 9, 10, p. 1635-6 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Implantable loop recorder detection of atrial fibrillation to prevent stroke (The LOOP Study): a randomised controlled trial

    Svendsen, Jesper Hastrup, Diederichsen, S. Z., Højberg, S., Krieger, D. W., Graff, C., Kronborg, C., Olesen, Morten Steen Salling, Nielsen, J. B., Holst, A. G., Brandes, A., Haugan, K. J. & Køber, Lars Valeur, 2021, In: The Lancet. 398, 10310, p. 1507-1516 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    IKs Gain- and Loss-of-Function In Early-Onset Lone Atrial Fibrillation

    Steffensen, Annette Buur, Refsgaard, L., Andersen, M. N., Vallet, C., Mujezinovic, A., Haunsø, Stig, Svendsen, Jesper Hastrup, Olesen, Søren-Peter, Olesen, Morten Steen Salling & Schmitt, Nicole, 2015, In: Journal of Cardiovascular Electrophysiology. 26, 7, p. 715-23 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    High prevalence of genetic variants previously associated with LQT syndrome in new exome data

    Refsgaard, L., Holst, A. G., Sadjadieh, G., Haunsø, Stig, Nielsen, J. B. & Olesen, Morten Steen Salling, Aug 2012, In: European Journal of Human Genetics. 20, 8, p. 905-8 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Genome-wide meta-analysis identifies 93 risk loci and enables risk prediction equivalent to monogenic forms of venous thromboembolism

    Ghouse, J., Tragante, V., Ahlberg, G., Rand, S. A., Jespersen, J. B., Leinøe, E. B., Vissing, C. R., Trudsø, L., Jonsdottir, I., Banasik, K., Brunak, S., Ostrowski, S. R., Pedersen, O. B., Sørensen, E., Erikstrup, C., Bruun, M. T., Nielsen, K. R., Køber, L., Christensen, A. H., Iversen, K. & 16 others, Jones, D., Knowlton, K. U., Nadauld, L., Halldorsson, G. H., Ferkingstad, E., Olafsson, I., Gretarsdottir, S., Onundarson, P. T., Sulem, P., Thorsteinsdottir, U., Thorgeirsson, G., Gudbjartsson, D. F., Stefansson, K., Holm, H., Olesen, Morten Steen Salling & Bundgård, Henning, 2023, In: Nature Genetics. 55, p. 399-409 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Genome-wide association study identifies locus at chromosome 2q32.1 associated with syncope and collapse

    lvs502, lvs502, Andreasen, Laura Korsholm, Hagen, C. M., Ahlberg, G., Ghouse, Jonas, Bækvad-Hansen, M., Bybjerg-Grauholm, J., Hougaard, D. M., Hedley, P., Haunsø, Stig, Svendsen, Jesper Hastrup, Kanters, Jørgen K., Jepps, Thomas Andrew Qvistgaard, Skov, M. W., Christiansen, M. & Olesen, Morten Steen Salling, 2020, In: Cardiovascular Research. 116, 1, p. 138-148

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Genome-wide association study identifies 18 novel loci associated with left atrial volume and function

    Ahlberg, G., Andreasen, L., Ghouse, Jonas, Bertelsen, L., Bundgård, Henning, Haunsø, Stig, Svendsen, Jesper Hastrup & Olesen, Morten Steen Salling, 2021, In: European Heart Journal. 42, 44, p. 4523–4534

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Genome-wide Study of Atrial Fibrillation Identifies Seven Risk Loci and Highlights Biological Pathways and Regulatory Elements Involved in Cardiac Development

    Nielsen, J. B., Fritsche, L. G., Zhou, W., Teslovich, T. M., Holmen, O. L., Gustafsson, S., Gabrielsen, M. E., Schmidt, E. M., Beaumont, R., Wolford, B. N., Lin, M., Brummett, C. M., Preuss, M. H., Refsgaard, L., Bottinger, E. P., Graham, S. E., Surakka, I., Chu, Y., Skogholt, A. H., Dalen, H. & 25 others, Boyle, A. P., Oral, H., Herron, T. J., Kitzman, J., Jalife, J., Svendsen, Jesper Hastrup, Olesen, Morten Steen Salling, Njølstad, I., Løchen, M., Baras, A., Gottesman, O., Marcketta, A., O'Dushlaine, C., Ritchie, M. D., Wilsgaard, T., Loos, R. J. F., Frayling, T. M., Boehnke, M., Ingelsson, E., Carey, D. J., Dewey, F. E., Kang, H. M., Abecasis, G. R., Hveem, K. & Willer, C. J., 2018, In: American Journal of Human Genetics. 102, 1, p. 103-115 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Genome wide association study based on cardiac magnetic resonance imaging in 23,634 individuals identifies five new loci associated with left atrial enlargement

    Ahlberg, G., Andreasen, Laura Korsholm, Ghouse, Jonas, Haunsø, Stig, Svendsen, Jesper Hastrup & Olesen, Morten Steen Salling, 2020, In: European Journal of Human Genetics. 28, SUPPL 1, p. 63-64

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  72. Published

    Genetically predicted adipose tissue distribution influences the risk of atherosclerosis

    Vad, Oliver Tim Bundgaard, Paludan-Müller, Christian, Monfort, L. M., Ahlberg, Gustav, Svendsen, Jesper Hastrup & Olesen, Morten Steen Salling, 2023, In: European Journal of Preventive Cardiology. 30, 7, p. e41–e45

    Research output: Contribution to journalLetterResearchpeer-review

  73. Published

    Genetic variation in the two-pore domain potassium channel, TASK-1, may contribute to an atrial substrate for arrhythmogenesis

    Liang, B., Soka, M., Christensen, Alex Hørby, Olesen, Morten Steen Salling, Larsen, A. P., Knop, Filip Krag, Wang, F., Nielsen, J. B., Andersen, M. N., Humphreys, D., Mann, S. A., Huttner, I. G., Vandenberg, J. I., Svendsen, Jesper Hastrup, Haunsø, Stig, Preiss, T., Seebohm, G., Olesen, Søren-Peter, Schmitt, Nicole & Fatkin, D., 27 Dec 2013, In: Journal of Molecular and Cellular Cardiology. 67, p. 69-76 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Genetic variants on chromosomes 7p31 and 12p12 are associated with abnormal atrial electrical activation in patients with early-onset lone atrial fibrillation

    Seifert, M. B., Olesen, Morten Steen Salling, Christophersen, I. E., Nielsen, J. B., Carlson, J., Holmqvist, F., Tveit, A., Haunsø, Stig, Svendsen, Jesper Hastrup & Platonov, P. G., 2019, In: Annals of Noninvasive Electrocardiology (Online). 24, 6, 9 p., e12661.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Genetic aspects of lone atrial fibrillation: what do we know?

    Andreasen, Laura Korsholm, Nielsen, J. B. & Olesen, Morten Steen Salling, 2015, In: Current Pharmaceutical Design. 21, 5, p. 667-78 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  76. Published

    Genetic architecture of spatial electrical biomarkers for cardiac arrhythmia and relationship with cardiovascular disease

    Young, W. J., Haessler, J., Benjamins, J-W., Repetto, L., Yao, J., Isaacs, A., Harper, A. R., Ramirez, J., Garnier, S., van Duijvenboden, S., Baldassari, A. R., Concas, M. P., Duong, T., Foco, L., Isaksen, J. L., Mei, H., Noordam, R., Nursyifa, C., Richmond, A., Santolalla, M. L. & 74 others, Sitlani, C. M., Soroush, N., Thériault, S., Trompet, S., Aeschbacher, S., Ahmadizar, F., Alonso, A., Brody, J. A., Campbell, A., Correa, A., Darbar, D., De Luca, A., Deleuze, J., Ellervik, Christina, Fuchsberger, C., Goel, A., Grace, C., Guo, X., Hansen, Torben, Heckbert, S. R., Jackson, R. D., Kors, J. A., Lima-Costa, M. F., Linneberg, Allan René, Macfarlane, P. W., Morrison, A. C., Navarro, P., Porteous, D. J., Pramstaller, P. P., Reiner, A. P., Risch, L., Schotten, U., Shen, X., Sinagra, G., Soliman, E. Z., Stoll, M., Tarazona-Santos, E., Tinker, A., Trajanoska, K., Villard, E., Warren, H. R., Whitsel, E. A., Wiggins, K. L., Arking, D. E., Avery, C. L., Conen, D., Girotto, G., Grarup, Niels, Hayward, C., Jukema, J. W., Mook-Kanamori, D. O., Olesen, Morten Steen Salling, Padmanabhan, S., Psaty, B. M., Pattaro, C., Ribeiro, A. L. P., Rotter, J. I., Stricker, B. H., van der Harst, P., van Duijn, C. M., Verweij, N., Wilson, J. G., Orini, M., Charron, P., Watkins, H., Kooperberg, C., Lin, H. J., Wilson, J. F., Kanters, Jørgen K., Sotoodehnia, N., Mifsud, B., Lambiase, P. D., Tereshchenko, L. G. & Munroe, P. B., 14 Mar 2023, In: Nature Communications. 14, 1, 16 p., 1411.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways

    Young, W. J., Lahrouchi, N., Isaacs, A., Duong, T., Foco, L., Ahmed, F., Brody, J. A., Salman, R., Noordam, R., Benjamins, J-W., Haessler, J., Lyytikäinen, L-P., Repetto, L., Concas, M. P., van den Berg, M. E., Weiss, S., Baldassari, A. R., Bartz, T. M., Cook, J. P., Evans, D. S. & 31 others, Freudling, R., Hines, O., Isaksen, Jonas L., Lin, H., Mei, H., Moscati, A., Müller-Nurasyid, M., Nursyifa, Casia, Qian, Y., Richmond, A., Roselli, C., Ryan, K. A., Tarazona-Santos, E., Thériault, S., van Duijvenboden, S., Warren, H. R., Yao, J., Raza, D., Aeschbacher, S., Ahlberg, Gustav, Andreasen, Laura Korsholm, Ellervik, Christina, Hansen, Torben, Jackson, R. D., Lind, L., Linneberg, Allan René, Grarup, Niels, Kanters, Jørgen K., Loos, Ruth, Olesen, Morten Steen Salling & CHARGE Consortium, C. C., 2022, In: Nature Communications. 13, 1, 18 p., 5144.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Genetic Variants Close to TTN, NKX2-5, and MYH6 Associate With AVNRT

    Andreasen, L., Ahlberg, G., Ægisdóttir, H. M., Sveinbjörnsson, G., Lundegaard, P. R., Hartmann, J. P., Paludan-Müller, C., Hadji-Turdeghal, K., Ghouse, J., Pehrson, S., Jensen, H. K., Riahi, S., Hansen, J., Sandgaard, N., Sørensen, E., Banasik, K., Sækmose, S. G., Bruun, M. T., Hjalgrim, H., Erikstrup, C. & 18 others, Pedersen, Ole Birger Vesterager, Wittig, M., Haunsø, Stig, Ostrowski, Sisse Rye, Genomic Consortium, D., Franke, A., Brunak, Søren, Kanters, Jørgen K., Ellervik, Christina, Bundgård, Henning, Ullum, H., Gudbjartsson, D. F., Thorsteinsdottir, U., Holm, H., Arnar, D. O., Stefansson, K., Svendsen, Jesper Hastrup & Olesen, Morten Steen Salling, 2022, In: Circulation Research. 131, 10, p. 862-865

    Research output: Contribution to journalLetterResearchpeer-review

  79. Published

    Genetic Modifier of the QTc Interval Associated With Early-Onset Atrial Fibrillation

    Andreasen, Laura Korsholm, Nielsen, J. B., Christophersen, I. E., Holst, A. G., Sajadieh, Ahmad, Tveit, A., Haunsø, Stig, Svendsen, Jesper Hastrup, Schmitt, Nicole & Olesen, Morten Steen Salling, Oct 2013, In: Canadian Journal of Cardiology. 29, 10, p. 1234-40 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    Genetic Misdiagnoses and the Potential for Health Disparities

    Manrai, A. K., Funke, B. H., Rehm, H. L., Olesen, Morten Steen Salling, Maron, B. A., Szolovits, P., Margulies, D. M., Loscalzo, J. & Kohane, I. S., 18 Aug 2016, In: New England Journal of Medicine. 375, 7, p. 655-65 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Genetic Atrial Cardiomyopathies: Common Features, Specific Differences, and Broader Relevance to Understanding Atrial Cardiomyopathy

    Marcoux, E., Sosnowski, D., Ninni, S., MacKasey, M., Cadrin-Tourigny, J., Roberts, J. D., Olesen, Morten Steen Salling, Fatkin, D. & Nattel, S., Dec 2023, In: Circulation: Arrhythmia and Electrophysiology. 16, 12, p. 675-698

    Research output: Contribution to journalReviewResearchpeer-review

  82. Generation of induced pluripotent stem cells (iPSC) from an atrial fibrillation patient carrying a PITX2 p.M200V mutation

    Mora, C., Serzanti, M., Giacomelli, A., Beltramone, S., Marchina, E., Bertini, V., Piovani, G., Refsgaard, L., Olesen, Morten Steen Salling, Cortellini, V. & Dell'Era, P., Oct 2017, In: Stem Cell Research. 24, p. 8-11 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Generation of induced pluripotent stem cells (iPSC) from an atrial fibrillation patient carrying a KCNA5 p.D322H mutation

    Mora, C., Serzanti, M., Giacomelli, A., Turco, V., Marchina, E., Bertini, V., Piovani, G., Savio, G., Refsgaard, L., Olesen, Morten Steen Salling, Cortellini, V. & Dell'Era, P., Oct 2017, In: Stem Cell Research. 24, p. 29-32 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Gain-of-function mutations in potassium channel subunit KCNE2 associated with early-onset lone atrial fibrillation

    Nielsen, J. B., Bentzen, Bo Hjorth, Olesen, Morten Steen Salling, David, J., Olesen, Søren-Peter, Haunsø, Stig, Svendsen, Jesper Hastrup & Schmitt, Nicole, Apr 2014, In: Biomarkers in Medicine. 8, 4, p. 557-570 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Gain-of-function mutation in the voltage-gated potassium channel gene KCNQ1 and glucose-stimulated hypoinsulinemia - case report

    Zhang, J., Juhl, C. R., Hylten-Cavallius, L., Olesen, Morten Steen Salling, Linneberg, Allan René, Holst, Jens Juul, Hansen, Torben, Kanters, Jørgen K. & Torekov, Signe Sørensen, 2020, In: B M C Endocrine Disorders. 20, 5 p., 38.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Functional consequences of genetic variation in sodium channel modifiers in early onset lone atrial fibrillation

    Denti, F., Paludan-Müller, Christian, Olesen, Søren-Peter, Haunsø, Stig, Svendsen, Jesper Hastrup, Olesen, Morten Steen Salling, Bentzen, Bo Hjorth & Schmitt, Nicole, Mar 2018, In: Personalized Medicine. 15, 2, p. 93-102 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Fascicular heart blocks and risk of adverse cardiovascular outcomes: Results from a large primary care population

    Nyholm, B. C., Ghouse, J., Lee, C. J. Y., Rasmussen, P. V., Pietersen, A., Hansen, S. M., Torp-Pedersen, Christian, Køber, Lars Valeur, Haunsø, Stig, Olesen, Morten Steen Salling, Svendsen, Jesper Hastrup, Graff, C., Holst, A. G., Nielsen, J. B. & Skov, M. W., 2022, In: Heart Rhythm. 19, 2, p. 252-259 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Familial atrial fibrillation predicts increased risk of mortality: A study in Danish twins

    Christophersen, I. E., Budtz-Joergensen, Esben, Olesen, Morten Steen Salling, Haunsø, Stig, Christensen, K. & Svendsen, Jesper Hastrup, 2013, In: Circulation: Arrhythmia and Electrophysiology. 6, 1, p. 10-15 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Explaining deep neural networks for knowledge discovery in electrocardiogram analysis

    Hicks, S. A., Isaksen, Jonas L., Thambawita, V., Ghouse, Jonas, Ahlberg, Gustav, Linneberg, Allan René, Grarup, Niels, Strümke, I., Ellervik, Christina, Olesen, Morten Steen Salling, Hansen, Torben, Graff, C., von Holstein-Rathlou, Niels-Henrik, Halvorsen, P., Maleckar, M. M., Riegler, M. A. & Kanters, Jørgen K., 2021, In: Scientific Reports. 11, 1, 11 p., 10949.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Erratum: Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death (Nature Genetics (2013) 45 (1044-1049))

    Brugada GWAS Genetics, B. G. G., 1 Nov 2013, In: Nature Genetics. 45, 11, 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  91. Published

    Epicardial adipose tissue and subclinical incident atrial fibrillation as detected by continuous monitoring: a cardiac magnetic resonance imaging study

    Guldberg, E., Diederichsen, S. Z., Haugan, K. J., Brandes, A., Graff, C., Krieger, D., Olesen, Morten Steen Salling, Højberg, S., Køber, Lars Valeur, Vejlstrup, N., Bertelsen, L. & Svendsen, Jesper Hastrup, 2024, In: International Journal of Cardiovascular Imaging. 40, p. 591–599

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Enhancing rare variant interpretation in inherited arrhythmias through quantitative analysis of consortium disease cohorts and population controls

    Nantes Referral Center for inherited cardiac arrhythmia, N. R. C. F. I. C. A., 2021, In: Genetics In Medicine. 23, p. 47–58 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Electrocardiographic markers of subclinical atrial fibrillation detected by implantable loop recorder: insights from the LOOP Study

    Xing, L. Y., Diederichsen, S. Z., Hojberg, S., Krieger, D. W., Graff, C., Olesen, Morten Steen Salling, Nielsen, J. B., Brandes, A., Køber, Lars Valeur, Haugan, K. J. & Svendsen, Jesper Hastrup, 2023, In: Europace. 25, 5, 10 p., euad014.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Electrocardiographic Tpeak-Tend interval and risk of cardiovascular morbidity and mortality: Results from the Copenhagen ECG study

    Bachmann, T. N., Skov, M. W., Rasmussen, P., Graff, C., Pietersen, A., Lind, B., Struijk, J. J., Olesen, Morten Steen Salling, Haunsø, Stig, Køber, Lars Valeur, Svendsen, Jesper Hastrup, Holst, A. G. & Nielsen, J. B., Apr 2016, In: Heart rhythm : the official journal of the Heart Rhythm Society. 13, 4, p. 915-924 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Electrocardiographic T-wave morphology and risk of mortality

    Isaksen, Jonas L., Ghouse, J., Graff, C., Olesen, Morten Steen Salling, Holst, A. G., Pietersen, A., Nielsen, J. B., Skov, M. W. & Kanters, Jørgen K., 2021, In: International Journal of Cardiology. 328, p. 199-205

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    Electrocardiographic Precordial ST‐Segment Deviations and the Risk of Cardiovascular Death: Results From the Copenhagen ECG Study

    Rasmussen, P. V., Nielsen, J. B., Pietersen, A., Graff, C., Lind, B., Struijk, J. J., Olesen, Morten Steen Salling, Haunsø, Stig, Køber, Lars Valeur, Svendsen, Jesper Hastrup & Holst, A. G., Jun 2014, In: American Heart Association. Journal. Cardiovascular and Cerebrovascular Disease. 3, 3, p. 1-16 16 p., e000549.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    Electrocardiographic PR Interval Duration and Cardiovascular Risk: Results From the Copenhagen ECG Study

    Rasmussen, P. V., Nielsen, J. B., Skov, M. W., Pietersen, A., Graff, C., Lind, B., Struijk, J. J., Olesen, Morten Steen Salling, Haunsø, Stig, Køber, Lars Valeur, Svendsen, Jesper Hastrup & Holst, A. G., May 2017, In: Canadian Journal of Cardiology. 33, 5, p. 674-681 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    Electrocardiographic Morphology-Voltage-P-Wave-Duration (MVP) Score to Select Patients for Continuous Atrial Fibrillation Screening to Prevent Stroke

    Xing, L. Y., Diederichsen, S. Z., Højberg, S., Krieger, D., Graff, C., Olesen, Morten Steen Salling, Nielsen, J. B., Brandes, A., Køber, Lars Valeur, Haugan, K. J. & Svendsen, Jesper Hastrup, 2023, In: American Journal of Cardiology. 205, p. 457-464 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Electrocardiographic Findings, Arrhythmias, and Left Ventricular Involvement in Familial ST-Depression Syndrome

    Christensen, Alex Hørby, Vissing, C. R., Pietersen, A., Tfelt-Hansen, Jacob, Jensen, Thomas Hartvig Lindkær, Pehrson, S., Henriksen, F. L., Sandgaard, N. C. F., Iversen, Kasper, Jensen, H. K., Olesen, Morten Steen Salling & Bundgård, Henning, 2022, In: Circulation. Arrhythmia and electrophysiology. 15, 4, p. 231-240 e010688.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Effects of Atrial Fibrillation Screening According to N-Terminal Pro-B-Type Natriuretic Peptide: A Secondary Analysis of the Randomized LOOP Study

    Xing, L. Y., Diederichsen, S. Z., Højberg, S., Krieger, D. W., Graff, C., Frikke-Schmidt, Ruth, Olesen, Morten Steen Salling, Brandes, A., Køber, Lars Valeur, Haugan, K. J. & Svendsen, Jesper Hastrup, 2023, In: Circulation. 147, 24, p. 1788-1797 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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ID: 49763464