Jens Juul Holst
Professor
Endocrinology and Metabolism
Blegdamsvej 3
2200 København N.
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Linagliptin, a selective DPP-4 inhibitor, inhibits DPP-4, increases incretin levels, lowers glucagon, and improves glycaemic control in patients with Type 2 diabetes.
Rauch, T., Graefe-Mody, U., Deacon, Carolyn F., Ring, A., Holst, Jens Juul, Woerle, H., Dugi, K. & Heise, T., 2012, In: Diabetes Therapy. 3, 1, p. 10Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of Peripheral Neurotensin on Appetite Regulation and Its Role in Gastric Bypass Surgery
Ratner, C., Skov, Louise Julie, Raida, Z., Bächler, T., Bellmann-Sickert, K., Le Foll, C., Sivertsen, B., Dalbøge, L. S., Hartmann, Bolette, Beck-Sickinger, A. G., Madsen, A. N., Jelsing, J., Holst, Jens Juul, Lutz, T. A., Andrews, Z. B. & Holst, Birgitte, Sep 2016, In: Endocrinology. 157, 9, p. 3482-92 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Regulation of secretion of pancreatic spasmolytic polypeptide from porcine pancreas
Rasmussen, T. N., Harling, H., Thim, L., Pierzynowski, S., Weström, B. R. & Holst, Jens Juul, 1993, In: The American Journal of Physiology. p. G22-G29Research output: Contribution to journal › Journal article › Research › peer-review
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Calcitonin gene-related peptide: effect on contractile activity and luminal-cross-sectional area in isolated, perfused porcine ileum
Rasmussen, T. N., Gregersen, H., Harling, H. & Holst, Jens Juul, 1993, In: Scandinavian Journal of Gastroenterology. 27, p. 787-792Research output: Contribution to journal › Journal article › Research › peer-review
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Immunohistochemical localization of pancreatic spasmolytic polypeptide in the pig
Rasmussen, T. N., Raaberg, L., Poulsen, S. S., Thim, L. & Holst, Jens Juul, 1992, In: Histochemistry. 98, p. 113-119Research output: Contribution to journal › Journal article › Research › peer-review
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Localisation and neural control of the release of calcitonin gene-related peptide (CGRP) from the isolated perfused porcine ileum
Rasmussen, T. N., Schmidt, P., Poulsen, S. S., Holst, Jens Juul & Poulsen, Steen Seier, 20 Apr 2001, In: Regulatory Peptides. 98, 3, p. 137-143 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pigs produce only a single form of CGRP, part of which is processed to N- and C-terminal fragments
Rasmussen, T. N., Bersani, M., Johnsen, A. H., Kofod, H. & Holst, Jens Juul, 1994, In: Peptides. 15, 1, p. 89-94 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Isolation and molecular characterization of porcine calcitonin gene-related peptide (CGRP) and its endocrine effects in the porcine pancreas
Rasmussen, T. N., Bersani, M., Schmidt, P., Thim, L., Kofod, H., Jørgensen, P. N., Poulsen, Steen Seier & Holst, Jens Juul, Mar 1998, In: Pancreas. 16, 2, p. 195-204 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of calcitonin gene-related peptide (CGRP) on motility and on the release of substance P, neurokinin A, somatostatin and gastrin in the isolated perfused porcine antrum
Rasmussen, T. N., Schmidt, P., Poulsen, S. S., Holst, Jens Juul & Poulsen, Steen Seier, 1 Aug 2001, In: Neurogastroenterology and Motility. 13, 4, p. 353-359 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A double-blind placebo-controlled study on the effects of omeprazole on gut hormone secretion and gastric emptying rate.
Rasmussen, L., Qvist, N., Øster-Jørgensen, E., Rehfeld, J. F., Holst, Jens Juul & Pedersen, S. A., 1997, In: Scandinavian Journal of Gastroenterology. 32, p. 900-905Research output: Contribution to journal › Journal article › Research › peer-review
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Preanalytical impact on the accuracy of measurements of glucagon, GLP-1 and GIP in clinical trials
Rasmussen, C., Richter, Michael Martin, Jensen, N. J., Heinz, N., Hartmann, Bolette, Holst, Jens Juul, Kjeldsen, Sasha Alexandra Sampson & Albrechtsen, Nicolai Jacob Wewer, 2023, In: Scandinavian Journal of Clinical and Laboratory Investigation. 83, 8, p. 591-598Research output: Contribution to journal › Journal article › Research › peer-review
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The intestinotrophic peptide, GLP-2, counteracts the gastrointestinal atrophy in mice induced by the epidermal growth factor receptor inhibitor, erlotinib, and cisplatin
Rasmussen, A. R., Viby, N., Hare, K. J., Hartmann, Bolette, Thim, L., Holst, Jens Juul & Poulsen, Steen Seier, 1 Oct 2010, In: Digestive Diseases and Sciences. 55, 10, p. 2785-96 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Impaired incretin response after a mixed meal is associated with insulin resistance in nondiabetic men
Rask, E., Olsson, T., Soderberg, S. & Holst, Jens Juul, 2001, In: Diabetes Care. 24, p. 1640-1645Research output: Contribution to journal › Journal article › Research › peer-review
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Insulin secretion and incretin hormones after oral glucose in impaired glucose tolerance
Rask, E., Olsson, T., Söderberg, S., Holst, Jens Juul, Tura, A., Pacini, G. & Ahren, B., 2004, In: Metabolism. 53, p. 624-631Research output: Contribution to journal › Journal article › Research › peer-review
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Insulin secretion and incretin hormones after oral glucose in non-obese subjects with impaired glucose tolerance
Rask, E., Olsson, T., Söderberg, S., Holst Jj, J. J., Tura, A., Pacini, G., Ahrén, B. & Holst, Jens Juul, May 2004, In: Metabolism. 53, 5, p. 624-31 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Relationship between Optimum Mini‐doses of Glucagon and Insulin Levels when Treating Mild Hypoglycaemia in Patients with Type 1 Diabetes: A Simulation Study
Ranjan, A., Wendt, S. L., Schmidt, S., Madsbad, Sten, Holst, Jens Juul, Madsen, H., Knudsen, C. B., Jørgensen, J. B. & Nørgaard, Kirsten, 2018, In: Basic & Clinical Pharmacology & Toxicology. 122, 3, p. 322-330Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of subcutaneous, low-dose glucagon on insulin-induced mild hypoglycaemia in patients with insulin pump treated type 1 diabetes
Ranjan, A., Schmidt, S., Madsbad, Sten, Holst, Jens Juul & Nørgaard, K., 7 Jan 2016, In: Diabetes, Obesity and Metabolism Online. 18, 4, p. 410-418Research output: Contribution to journal › Journal article › Research › peer-review
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Low-Carbohydrate Diet Impairs the Effect of Glucagon in the Treatment of Insulin-Induced Mild Hypoglycemia: A Randomized Crossover Study
Ranjan, A., Schmidt, S., Damm-Frydenberg, C., Steineck, I., Clausen, T. R., Holst, Jens Juul, Madsbad, Sten & Nørgaard, Kirsten, Jan 2017, In: Diabetes Care. 40, 1, p. 132-135 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Short-term effects of a low carbohydrate diet on glycaemic variables and cardiovascular risk markers in patients with type 1 diabetes: A randomized open-label crossover trial
Ranjan, A., Schmidt, S., Damm-Frydenberg, C., Holst, Jens Juul, Madsbad, Sten & Nørgaard, Kirsten, Oct 2017, In: Diabetes, Obesity and Metabolism. 19, 10, p. 1479-1484Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of Preceding Ethanol Intake on Glucose Response to Low-Dose Glucagon in Individuals With Type 1 Diabetes: A Randomized, Placebo-Controlled, Crossover Study
Ranjan, A., Nørgaard, Kirsten, Tetzschner, R., Steineck, I. I. K., Clausen, T. R., Holst, Jens Juul, Madsbad, Sten & Schmidt, S., 2018, In: Diabetes Care. 41, 4, p. 797-806Research output: Contribution to journal › Journal article › Research › peer-review
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Increased postprandial glycaemia, insulinemia, and lipidemia after 10 weeks’ sucrose-rich diet compared to an artificially sweetened diet: a randomised controlled trial
Raben, Anne, Møller, B. K., Flint, A., Vasilaris, T. H., Møller, A. C., Holst, Jens Juul & Astrup, A., 2011, In: Food & Nutrition Research. 55, 5961, 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Evidence for an abnormal postprandial response to a high-fat meal in women predisposed to obesity
Raben, Anne, Andersen, H. B., Christensen, N. J., Madsen, J., Holst, Jens Juul & Astrup, A., 1994, In: American Journal of Physiology: Endocrinology and Metabolism. 267, 4 part 1, p. E549-E559 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Decreased postprandial thermogenesis and fat oxidation, but increased fullness after a high-fiber meal compared to a low-fiber meal
Raben, A. B., Christensen, N. J., Madsen, J. J. V., Holst, Jens Juul & Astrup, A., 1994, In: Am. J. Clin. Nutr.. 59, p. 1386-1394Research output: Contribution to journal › Journal article › Research › peer-review
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Meals with similar energy densities but rich in protein, fat, carbohydrate, or alcohol have different effects on energy expenditure and substrate metabolism but not on appetite and energy intake
Raben, A. B., Agerholm-Larsen, L., Flint, A., Holst, Jens Juul & Astrup, A., 2003, In: American Journal of Clinical Nutrition. 77, 1, p. 91-100 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Diurnal metabolic profiles after 14 d of an ad libitum high-starch, high-sucrose, or high-fat diet in normal-weight never-obese and postobese women
Raben, A., Holst, Jens Juul, Madsen, J. & Astrup, A., 2001, In: American Journal of Clinical Nutrition. 73, p. 177-89 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Evidence for an abnormal postprandial response to a high-fat meal in women predisposed to obesity
Raben, A., Andersen, H. B., Christensen, N. J., Madsen, J. J. V., Holst, Jens Juul & Astrup, A., 1994, In: Am. J. Physiol.. 267, p. E549-E559Research output: Contribution to journal › Journal article › Research › peer-review
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Positive effects on plasma glucose & appetite by industrial modification of starch
Raben, A., Andersen, K., Karberg, M. A., Holst, Jens Juul & Astrup, A., 1996. 1 p.Research output: Contribution to conference › Poster › Research
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Postprandial lipid oxidation reduced and carbohydrate oxidation increased in postobese subjects
Raben, A., Andersen, H. B., Christensen, N. J., Madsen, J., Holst, Jens Juul & Astrup, A., 1994, Obesity in Europe. John Libbey, p. 135-137Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
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Resistant starch: The effect on postprandial glycemia, hormonal response and satiety
Raben, A., Tagliabue, A., Christensen, N. J., Madsen, J. J. V., Holst, Jens Juul & Astrup, A., 1994, In: Am. J. Clin. Nutr.. 60, p. 544-551Research output: Contribution to journal › Journal article › Research › peer-review
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Immunohistochemical localization of pancreatic spasmolytic polypeptide (PSP) in the pig
Raaberg, L., Poulsen, Steen Seier, Thim, L. & Holst, Jens Juul, Sep 1992, In: Histochemistry. 98, 2, p. 113-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Increases in plasma motilin follow each episode of gallbladder emptying during the interdigestive period and changes in serum bile acid concentration correlate to plasma motilin.
Qvist, N., Øster-Jørgensen, E., Pedersen, S. A., Rasmussen, L., Hovendal, C. & Holst, Jens Juul, 1995, In: Scandinavian Journal of Gastroenterology. 30, p. 122-127Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of active commuting and leisure-time exercise on appetite in individuals with overweight and obesity
Quist, Jonas Salling, Blond, Martin Bæk, Gram, A. S., Steenholt, C. B., Janus, C., Holst, Jens Juul, Rehfeld, Jens Frederik, Sjödin, Anders Mikael, Stallknecht, Bente Merete & Rosenkilde, M., 2019, In: Journal of Applied Physiology. 126, 4, p. 941-951Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of 3 months of 10-h per-day time-restricted eating and 3 months of follow-up on bodyweight and cardiometabolic health in Danish individuals at high risk of type 2 diabetes: the RESET single-centre, parallel, superiority, open-label, randomised controlled trial
Quist, Jonas Salling, Pedersen, H. E., Jensen, M. M., Clemmensen, K. K. B., Bjerre, N., Ekblond, T. S., Uldal, S., Størling, Joachim, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Torekov, Signe Sørensen, Nyeland, M. E., Vistisen, D., Jørgensen, M. E., Panda, S., Brock, C., Finlayson, G., Blond, Martin Bæk & Færch, K., 2024, In: The Lancet Healthy Longevity. 5, 5, p. e314-e325 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Protocol for a single-centre, parallel-group, randomised, controlled, superiority trial on the effects of time-restricted eating on body weight, behaviour and metabolism in individuals at high risk of type 2 diabetes: the REStricted Eating Time (RESET) study
Quist, Jonas Salling, Jensen, M. M., Clemmensen, K. K. B., Pedersen, H., Bjerre, N., Størling, Joachim, Blond, M. B., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Torekov, Signe Sørensen, Vistisen, D., Jørgensen, M. E., Panda, S., Brock, C., Finlayson, G. & Faerch, K., 2020, In: BMJ Open. 10, 8, 11 p., 037166.Research output: Contribution to journal › Journal article › Research › peer-review
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Insulintropic actions of intravenous glucagon-like peptide-1 (GLP-1) (7-36 amide) in the fasting state in healthy subjects
Qualmann, C., Nauck, M. A., Holst, Jens Juul, Ørskov, Cathrine & Creutzfeldt, W., 1995, In: Acta Diabetologica. 32, p. 13-16Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon-like peptide 1 (GLP-1)(7-36 amide) secretion in response to luminal sucrose from the upper and lower gut. A study using alpha-glucosidase inhibition (acarbose).
Qualmann, C., Nauck, M. A., Holst, Jens Juul, Ørskov, C. & Creutzfeldt, W., 1995, In: Scandinavian Journal of Gastroenterology. 30, p. 892-896Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon-like peptide 1 (7-36 amide) secretion in response to luminal sucrose from the upper and lower gut. A study using a-glucosidase inhibition (acarbose)
Qualmann, C., Nauck, M. A., Holst, Jens Juul, Ørskov, Cathrine & Creutzfeldt, W., 1995, In: Scandinavian Journal of Gastroenterology. 30, p. 892-896Research output: Contribution to journal › Journal article › Research › peer-review
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Meal-stimulated glucagon release is associated with postprandial blood glucose level and does not interfere with glycemic control in children and adolescents with new-onset type 1 diabetes
Pörksen, S., Nielsen, L. B., Kaas, A., Kocova, M., Chiarelli, F., Ørskov, Cathrine, Holst, Jens Juul, Ploug, K. B., Hougaard, P., Hansen, L. & Mortensen, H. B., Aug 2007, In: The Journal of clinical endocrinology and metabolism. 92, 8, p. 2910-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Comparison of sandwich ELISA and RIA for determination of exogenous GLP-1 (7-36 amide) in plasma.
Pridal, L., Ingwersen, S. H., Larsen, F. S., Holst, Jens Juul, Adelhorst, K. & Kirk, O., 1995, In: J Pharmaceutical and Biomedical Analysis. 13, p. 841-850Research output: Contribution to journal › Journal article › Research › peer-review
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Post-prandial secretion of glucagon-like peptide-2 (GLP-2) after carbohydrate-, fat- or protein enriched meals in healthy subjects
Prahm, A. P., Hvistendahl, M. K., Brandt, Christopher Filtenborg, Blanche, Paul Frédéric, Hartmann, Bolette, Holst, Jens Juul & Jeppesen, Palle Bekker, 2023, In: Peptides. 169, 8 p., 171091.Research output: Contribution to journal › Journal article › Research › peer-review
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The gastric acid secretagogue gastrin-releasing peptide and the inhibitor oxyntomodulin do not exert their effect directly on the parietal cell in the rat
Poulsen, Steen Seier & Holst, Jens Juul, 1988, In: Digestion. 40, 3, p. 144-51 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Substance P and neurokinin A are codistributed and colocalized in the porcine gastrointestinal tract
Poulsen, Steen Seier, Bersani, M., Holst, Jens Juul, Schmidt, P. & N. Rasmussen, T., 1991, In: Peptides. 12, 5, p. 963-73 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Immunohistochemical detection of ganglia in the rat stomach serosa, containing neurons immunoreactive for gastrin-releasing peptide and vasoactive intestinal peptide
Poulsen, Steen Seier & Holst, Jens Juul, 1987, In: Histochemistry. 87, 1, p. 47-52 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Galanin: distribution and effect on contractile activity and release of vasoactive intestinal polypeptide from the isolated perfused porcine ileum
Poulsen, Steen Seier & Holst, Jens Juul, 1990, In: Digestion. 47, 4, p. 191-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of oral glucose on systemic glucose metabolism during hyperinsulinaemic hypoglycemia in normal man
Poulsen, P. L., Grøfte, T., Holck, P., Møller, J., Schmitz, O., Ørskov, L., Holst, Jens Juul & Møller, N., 2000, In: Metabolism. 49, p. 1598-1603Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of dietary advanced glycation end products on postprandial appetite, inflammation, and endothelial activation in healthy overweight individuals
Poulsen, M. W., Bak, M. J., Andersen, J. M., Monošík, R., Giraudi-Futin, A. C., Holst, Jens Juul, Nielsen, J., Lauritzen, Lotte, Larsen, L. H., Bügel, Susanne Gjedsted & Dragsted, Lars Ove, 2014, In: European Journal of Nutrition. 53, 2, p. 661-672 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Meal-stimulated glucagon release is associated with postprandial blood glucose level and does not interfere with glycemic control in children and adolescents with new-onset type 1 diabetes
Porksen, S., Nielsen, L. B., Kaas, A., Kocova, M., Chiarelli, F., Orskov, C., Holst, Jens Juul, Ploug, K. B., Hougaard, P. P., Hansen, L. & Mortensen, H. B., 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 8, p. 2910-2916 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon-like peptide 1 increases mass but not frequency or orderliness of pulsatile insulin secretion
Porksen, N., Grøfte, T., Nyholm, B., Holst, Jens Juul, Pincus, S. M., Veldhuis, J. D., Schmitz, O. & Butler, P. C., 1998, In: Diabetes. 47, p. 45-49Research output: Contribution to journal › Journal article › Research › peer-review
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Octreotide suppresses the incretin GLP-1 in patients with acromegally, clinically nonfunctioning pituitary tumours and in healthy subjects
Plöckinger, U., Holst, Jens Juul, Messerschmidt, D., Hopfenmüller, W. & Quabbe, H. J., 1999, In: European Journal of Endocrinology. 140, p. 538-544Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of oral and intravenous glucose handling in truncally vagotomised subjects with pyloroplasty
Plamboeck, A., Veedfald, Simon, Deacon, Carolyn F., Hartmann, Bolette, Wettergren, A., Svendsen, Lars Bo, Meisner, S., Hovendal, C., Knop, Filip Krag, Vilsbøll, Tina & Holst, Jens Juul, 23 May 2013, In: European Journal of Endocrinology. 169, p. 187-201 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Meal induced gut hormone secretion is altered in aerobically trained compared to sedentary young healthy males
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Copenhagen study of overweight patients with coronary artery disease undergoing low energy diet or interval training: the randomized CUT-IT trial protocol
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Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial
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