Jens Juul Holst

Jens Juul Holst

Professor


  1. Published

    Linagliptin, a selective DPP-4 inhibitor, inhibits DPP-4, increases incretin levels, lowers glucagon, and improves glycaemic control in patients with Type 2 diabetes.

    Rauch, T., Graefe-Mody, U., Deacon, Carolyn F., Ring, A., Holst, Jens Juul, Woerle, H., Dugi, K. & Heise, T., 2012, In: Diabetes Therapy. 3, 1, p. 10

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Effects of Peripheral Neurotensin on Appetite Regulation and Its Role in Gastric Bypass Surgery

    Ratner, C., Skov, Louise Julie, Raida, Z., Bächler, T., Bellmann-Sickert, K., Le Foll, C., Sivertsen, B., Dalbøge, L. S., Hartmann, Bolette, Beck-Sickinger, A. G., Madsen, A. N., Jelsing, J., Holst, Jens Juul, Lutz, T. A., Andrews, Z. B. & Holst, Birgitte, Sep 2016, In: Endocrinology. 157, 9, p. 3482-92 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Regulation of secretion of pancreatic spasmolytic polypeptide from porcine pancreas

    Rasmussen, T. N., Harling, H., Thim, L., Pierzynowski, S., Weström, B. R. & Holst, Jens Juul, 1993, In: The American Journal of Physiology. p. G22-G29

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Calcitonin gene-related peptide: effect on contractile activity and luminal-cross-sectional area in isolated, perfused porcine ileum

    Rasmussen, T. N., Gregersen, H., Harling, H. & Holst, Jens Juul, 1993, In: Scandinavian Journal of Gastroenterology. 27, p. 787-792

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Immunohistochemical localization of pancreatic spasmolytic polypeptide in the pig

    Rasmussen, T. N., Raaberg, L., Poulsen, S. S., Thim, L. & Holst, Jens Juul, 1992, In: Histochemistry. 98, p. 113-119

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Localisation and neural control of the release of calcitonin gene-related peptide (CGRP) from the isolated perfused porcine ileum

    Rasmussen, T. N., Schmidt, P., Poulsen, S. S., Holst, Jens Juul & Poulsen, Steen Seier, 20 Apr 2001, In: Regulatory Peptides. 98, 3, p. 137-143 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Pigs produce only a single form of CGRP, part of which is processed to N- and C-terminal fragments

    Rasmussen, T. N., Bersani, M., Johnsen, A. H., Kofod, H. & Holst, Jens Juul, 1994, In: Peptides. 15, 1, p. 89-94 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Isolation and molecular characterization of porcine calcitonin gene-related peptide (CGRP) and its endocrine effects in the porcine pancreas

    Rasmussen, T. N., Bersani, M., Schmidt, P., Thim, L., Kofod, H., Jørgensen, P. N., Poulsen, Steen Seier & Holst, Jens Juul, Mar 1998, In: Pancreas. 16, 2, p. 195-204 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Effect of calcitonin gene-related peptide (CGRP) on motility and on the release of substance P, neurokinin A, somatostatin and gastrin in the isolated perfused porcine antrum

    Rasmussen, T. N., Schmidt, P., Poulsen, S. S., Holst, Jens Juul & Poulsen, Steen Seier, 1 Aug 2001, In: Neurogastroenterology and Motility. 13, 4, p. 353-359 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    A double-blind placebo-controlled study on the effects of omeprazole on gut hormone secretion and gastric emptying rate.

    Rasmussen, L., Qvist, N., Øster-Jørgensen, E., Rehfeld, J. F., Holst, Jens Juul & Pedersen, S. A., 1997, In: Scandinavian Journal of Gastroenterology. 32, p. 900-905

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Preanalytical impact on the accuracy of measurements of glucagon, GLP-1 and GIP in clinical trials

    Rasmussen, C., Richter, Michael Martin, Jensen, N. J., Heinz, N., Hartmann, Bolette, Holst, Jens Juul, Kjeldsen, Sasha Alexandra Sampson & Albrechtsen, Nicolai Jacob Wewer, 2023, In: Scandinavian Journal of Clinical and Laboratory Investigation. 83, 8, p. 591-598

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    The intestinotrophic peptide, GLP-2, counteracts the gastrointestinal atrophy in mice induced by the epidermal growth factor receptor inhibitor, erlotinib, and cisplatin

    Rasmussen, A. R., Viby, N., Hare, K. J., Hartmann, Bolette, Thim, L., Holst, Jens Juul & Poulsen, Steen Seier, 1 Oct 2010, In: Digestive Diseases and Sciences. 55, 10, p. 2785-96 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Impaired incretin response after a mixed meal is associated with insulin resistance in nondiabetic men

    Rask, E., Olsson, T., Soderberg, S. & Holst, Jens Juul, 2001, In: Diabetes Care. 24, p. 1640-1645

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Insulin secretion and incretin hormones after oral glucose in impaired glucose tolerance

    Rask, E., Olsson, T., Söderberg, S., Holst, Jens Juul, Tura, A., Pacini, G. & Ahren, B., 2004, In: Metabolism. 53, p. 624-631

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Insulin secretion and incretin hormones after oral glucose in non-obese subjects with impaired glucose tolerance

    Rask, E., Olsson, T., Söderberg, S., Holst Jj, J. J., Tura, A., Pacini, G., Ahrén, B. & Holst, Jens Juul, May 2004, In: Metabolism. 53, 5, p. 624-31 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Relationship between Optimum Mini‐doses of Glucagon and Insulin Levels when Treating Mild Hypoglycaemia in Patients with Type 1 Diabetes: A Simulation Study

    Ranjan, A., Wendt, S. L., Schmidt, S., Madsbad, Sten, Holst, Jens Juul, Madsen, H., Knudsen, C. B., Jørgensen, J. B. & Nørgaard, Kirsten, 2018, In: Basic & Clinical Pharmacology & Toxicology. 122, 3, p. 322-330

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Effects of subcutaneous, low-dose glucagon on insulin-induced mild hypoglycaemia in patients with insulin pump treated type 1 diabetes

    Ranjan, A., Schmidt, S., Madsbad, Sten, Holst, Jens Juul & Nørgaard, K., 7 Jan 2016, In: Diabetes, Obesity and Metabolism Online. 18, 4, p. 410-418

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Low-Carbohydrate Diet Impairs the Effect of Glucagon in the Treatment of Insulin-Induced Mild Hypoglycemia: A Randomized Crossover Study

    Ranjan, A., Schmidt, S., Damm-Frydenberg, C., Steineck, I., Clausen, T. R., Holst, Jens Juul, Madsbad, Sten & Nørgaard, Kirsten, Jan 2017, In: Diabetes Care. 40, 1, p. 132-135 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Short-term effects of a low carbohydrate diet on glycaemic variables and cardiovascular risk markers in patients with type 1 diabetes: A randomized open-label crossover trial

    Ranjan, A., Schmidt, S., Damm-Frydenberg, C., Holst, Jens Juul, Madsbad, Sten & Nørgaard, Kirsten, Oct 2017, In: Diabetes, Obesity and Metabolism. 19, 10, p. 1479-1484

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Effects of Preceding Ethanol Intake on Glucose Response to Low-Dose Glucagon in Individuals With Type 1 Diabetes: A Randomized, Placebo-Controlled, Crossover Study

    Ranjan, A., Nørgaard, Kirsten, Tetzschner, R., Steineck, I. I. K., Clausen, T. R., Holst, Jens Juul, Madsbad, Sten & Schmidt, S., 2018, In: Diabetes Care. 41, 4, p. 797-806

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Increased postprandial glycaemia, insulinemia, and lipidemia after 10 weeks’ sucrose-rich diet compared to an artificially sweetened diet: a randomised controlled trial

    Raben, Anne, Møller, B. K., Flint, A., Vasilaris, T. H., Møller, A. C., Holst, Jens Juul & Astrup, A., 2011, In: Food & Nutrition Research. 55, 5961, 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Evidence for an abnormal postprandial response to a high-fat meal in women predisposed to obesity

    Raben, Anne, Andersen, H. B., Christensen, N. J., Madsen, J., Holst, Jens Juul & Astrup, A., 1994, In: American Journal of Physiology: Endocrinology and Metabolism. 267, 4 part 1, p. E549-E559 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Decreased postprandial thermogenesis and fat oxidation, but increased fullness after a high-fiber meal compared to a low-fiber meal

    Raben, A. B., Christensen, N. J., Madsen, J. J. V., Holst, Jens Juul & Astrup, A., 1994, In: Am. J. Clin. Nutr.. 59, p. 1386-1394

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Meals with similar energy densities but rich in protein, fat, carbohydrate, or alcohol have different effects on energy expenditure and substrate metabolism but not on appetite and energy intake

    Raben, A. B., Agerholm-Larsen, L., Flint, A., Holst, Jens Juul & Astrup, A., 2003, In: American Journal of Clinical Nutrition. 77, 1, p. 91-100 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Diurnal metabolic profiles after 14 d of an ad libitum high-starch, high-sucrose, or high-fat diet in normal-weight never-obese and postobese women

    Raben, A., Holst, Jens Juul, Madsen, J. & Astrup, A., 2001, In: American Journal of Clinical Nutrition. 73, p. 177-89 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Evidence for an abnormal postprandial response to a high-fat meal in women predisposed to obesity

    Raben, A., Andersen, H. B., Christensen, N. J., Madsen, J. J. V., Holst, Jens Juul & Astrup, A., 1994, In: Am. J. Physiol.. 267, p. E549-E559

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Positive effects on plasma glucose & appetite by industrial modification of starch

    Raben, A., Andersen, K., Karberg, M. A., Holst, Jens Juul & Astrup, A., 1996. 1 p.

    Research output: Contribution to conferencePosterResearch

  28. Published

    Postprandial lipid oxidation reduced and carbohydrate oxidation increased in postobese subjects

    Raben, A., Andersen, H. B., Christensen, N. J., Madsen, J., Holst, Jens Juul & Astrup, A., 1994, Obesity in Europe. John Libbey, p. 135-137

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  29. Published

    Resistant starch: The effect on postprandial glycemia, hormonal response and satiety

    Raben, A., Tagliabue, A., Christensen, N. J., Madsen, J. J. V., Holst, Jens Juul & Astrup, A., 1994, In: Am. J. Clin. Nutr.. 60, p. 544-551

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Immunohistochemical localization of pancreatic spasmolytic polypeptide (PSP) in the pig

    Raaberg, L., Poulsen, Steen Seier, Thim, L. & Holst, Jens Juul, Sep 1992, In: Histochemistry. 98, 2, p. 113-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Increases in plasma motilin follow each episode of gallbladder emptying during the interdigestive period and changes in serum bile acid concentration correlate to plasma motilin.

    Qvist, N., Øster-Jørgensen, E., Pedersen, S. A., Rasmussen, L., Hovendal, C. & Holst, Jens Juul, 1995, In: Scandinavian Journal of Gastroenterology. 30, p. 122-127

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Effects of active commuting and leisure-time exercise on appetite in individuals with overweight and obesity

    Quist, Jonas Salling, Blond, Martin Bæk, Gram, A. S., Steenholt, C. B., Janus, C., Holst, Jens Juul, Rehfeld, Jens Frederik, Sjödin, Anders Mikael, Stallknecht, Bente Merete & Rosenkilde, M., 2019, In: Journal of Applied Physiology. 126, 4, p. 941-951

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Effects of 3 months of 10-h per-day time-restricted eating and 3 months of follow-up on bodyweight and cardiometabolic health in Danish individuals at high risk of type 2 diabetes: the RESET single-centre, parallel, superiority, open-label, randomised controlled trial

    Quist, Jonas Salling, Pedersen, H. E., Jensen, M. M., Clemmensen, K. K. B., Bjerre, N., Ekblond, T. S., Uldal, S., Størling, Joachim, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Torekov, Signe Sørensen, Nyeland, M. E., Vistisen, D., Jørgensen, M. E., Panda, S., Brock, C., Finlayson, G., Blond, Martin Bæk & Færch, K., 2024, In: The Lancet Healthy Longevity. 5, 5, p. e314-e325 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Protocol for a single-centre, parallel-group, randomised, controlled, superiority trial on the effects of time-restricted eating on body weight, behaviour and metabolism in individuals at high risk of type 2 diabetes: the REStricted Eating Time (RESET) study

    Quist, Jonas Salling, Jensen, M. M., Clemmensen, K. K. B., Pedersen, H., Bjerre, N., Størling, Joachim, Blond, M. B., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Torekov, Signe Sørensen, Vistisen, D., Jørgensen, M. E., Panda, S., Brock, C., Finlayson, G. & Faerch, K., 2020, In: BMJ Open. 10, 8, 11 p., 037166.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Insulintropic actions of intravenous glucagon-like peptide-1 (GLP-1) (7-36 amide) in the fasting state in healthy subjects

    Qualmann, C., Nauck, M. A., Holst, Jens Juul, Ørskov, Cathrine & Creutzfeldt, W., 1995, In: Acta Diabetologica. 32, p. 13-16

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Glucagon-like peptide 1 (GLP-1)(7-36 amide) secretion in response to luminal sucrose from the upper and lower gut. A study using alpha-glucosidase inhibition (acarbose).

    Qualmann, C., Nauck, M. A., Holst, Jens Juul, Ørskov, C. & Creutzfeldt, W., 1995, In: Scandinavian Journal of Gastroenterology. 30, p. 892-896

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Glucagon-like peptide 1 (7-36 amide) secretion in response to luminal sucrose from the upper and lower gut. A study using a-glucosidase inhibition (acarbose)

    Qualmann, C., Nauck, M. A., Holst, Jens Juul, Ørskov, Cathrine & Creutzfeldt, W., 1995, In: Scandinavian Journal of Gastroenterology. 30, p. 892-896

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Meal-stimulated glucagon release is associated with postprandial blood glucose level and does not interfere with glycemic control in children and adolescents with new-onset type 1 diabetes

    Pörksen, S., Nielsen, L. B., Kaas, A., Kocova, M., Chiarelli, F., Ørskov, Cathrine, Holst, Jens Juul, Ploug, K. B., Hougaard, P., Hansen, L. & Mortensen, H. B., Aug 2007, In: The Journal of clinical endocrinology and metabolism. 92, 8, p. 2910-6 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Comparison of sandwich ELISA and RIA for determination of exogenous GLP-1 (7-36 amide) in plasma.

    Pridal, L., Ingwersen, S. H., Larsen, F. S., Holst, Jens Juul, Adelhorst, K. & Kirk, O., 1995, In: J Pharmaceutical and Biomedical Analysis. 13, p. 841-850

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Post-prandial secretion of glucagon-like peptide-2 (GLP-2) after carbohydrate-, fat- or protein enriched meals in healthy subjects

    Prahm, A. P., Hvistendahl, M. K., Brandt, Christopher Filtenborg, Blanche, Paul Frédéric, Hartmann, Bolette, Holst, Jens Juul & Jeppesen, Palle Bekker, 2023, In: Peptides. 169, 8 p., 171091.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    The gastric acid secretagogue gastrin-releasing peptide and the inhibitor oxyntomodulin do not exert their effect directly on the parietal cell in the rat

    Poulsen, Steen Seier & Holst, Jens Juul, 1988, In: Digestion. 40, 3, p. 144-51 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Substance P and neurokinin A are codistributed and colocalized in the porcine gastrointestinal tract

    Poulsen, Steen Seier, Bersani, M., Holst, Jens Juul, Schmidt, P. & N. Rasmussen, T., 1991, In: Peptides. 12, 5, p. 963-73 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Immunohistochemical detection of ganglia in the rat stomach serosa, containing neurons immunoreactive for gastrin-releasing peptide and vasoactive intestinal peptide

    Poulsen, Steen Seier & Holst, Jens Juul, 1987, In: Histochemistry. 87, 1, p. 47-52 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Galanin: distribution and effect on contractile activity and release of vasoactive intestinal polypeptide from the isolated perfused porcine ileum

    Poulsen, Steen Seier & Holst, Jens Juul, 1990, In: Digestion. 47, 4, p. 191-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Effects of oral glucose on systemic glucose metabolism during hyperinsulinaemic hypoglycemia in normal man

    Poulsen, P. L., Grøfte, T., Holck, P., Møller, J., Schmitz, O., Ørskov, L., Holst, Jens Juul & Møller, N., 2000, In: Metabolism. 49, p. 1598-1603

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Effect of dietary advanced glycation end products on postprandial appetite, inflammation, and endothelial activation in healthy overweight individuals

    Poulsen, M. W., Bak, M. J., Andersen, J. M., Monošík, R., Giraudi-Futin, A. C., Holst, Jens Juul, Nielsen, J., Lauritzen, Lotte, Larsen, L. H., Bügel, Susanne Gjedsted & Dragsted, Lars Ove, 2014, In: European Journal of Nutrition. 53, 2, p. 661-672 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Meal-stimulated glucagon release is associated with postprandial blood glucose level and does not interfere with glycemic control in children and adolescents with new-onset type 1 diabetes

    Porksen, S., Nielsen, L. B., Kaas, A., Kocova, M., Chiarelli, F., Orskov, C., Holst, Jens Juul, Ploug, K. B., Hougaard, P. P., Hansen, L. & Mortensen, H. B., 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 8, p. 2910-2916 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Glucagon-like peptide 1 increases mass but not frequency or orderliness of pulsatile insulin secretion

    Porksen, N., Grøfte, T., Nyholm, B., Holst, Jens Juul, Pincus, S. M., Veldhuis, J. D., Schmitz, O. & Butler, P. C., 1998, In: Diabetes. 47, p. 45-49

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Octreotide suppresses the incretin GLP-1 in patients with acromegally, clinically nonfunctioning pituitary tumours and in healthy subjects

    Plöckinger, U., Holst, Jens Juul, Messerschmidt, D., Hopfenmüller, W. & Quabbe, H. J., 1999, In: European Journal of Endocrinology. 140, p. 538-544

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Characterization of oral and intravenous glucose handling in truncally vagotomised subjects with pyloroplasty

    Plamboeck, A., Veedfald, Simon, Deacon, Carolyn F., Hartmann, Bolette, Wettergren, A., Svendsen, Lars Bo, Meisner, S., Hovendal, C., Knop, Filip Krag, Vilsbøll, Tina & Holst, Jens Juul, 23 May 2013, In: European Journal of Endocrinology. 169, p. 187-201 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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