Jens Juul Holst

Jens Juul Holst

Professor

ORCID: 0000-0001-6853-3805

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  1. Published

    Appetitregulering: et komplekst system

    Sloth, B. & Holst, Jens Juul, 2008, In: Perspektiv. 1, 8

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Effects of carbohydrate restriction on postprandial glucose metabolism, β-cell function, gut hormone secretion, and satiety in patients with type 2 diabetes

    Skytte, M. J., Samkani, A., Astrup, A., Frystyk, J., Rehfeld, Jens Frederik, Holst, Jens Juul, Madsbad, Sten, Burling, K., Fenger, M., Thomsen, M. N., Larsen, T. M., Krarup, T. & Haugaard, Steen Bendix, 2021, In: American Journal of Physiology: Endocrinology and Metabolism. 320, 1, p. E7-E18 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Effects of a highly controlled carbohydrate-reduced high-protein diet on markers of oxidatively generated nucleic acid modifications and inflammation in weight stable participants with type 2 diabetes: a randomized controlled trial

    Skytte, M. J., Samkani, A., Astrup, A., Larsen, T. M., Frystyk, J., Poulsen, Henrik Enghusen, Henriksen, T., Holst, Jens Juul, Andersen, Ove, Madsbad, Sten, Haugaard, Steen Bendix, Krarup, T. & Larsen, E. L., 2020, In: Scandinavian Journal of Clinical & Laboratory Investigation. 80, 5, p. 401-407 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    A carbohydrate-reduced high-protein diet improves HbA1c and liver fat content in weight stable participants with type 2 diabetes: a randomised controlled trial

    fbg982, fbg982, Samkani, A., Petersen, A. D., Thomsen, M. N., Astrup, A., Chabanova, E., Frystyk, J., Holst, Jens Juul, Thomsen, Henrik S., Madsbad, Sten, Larsen, T. M., Haugaard, Steen Bendix & Krarup, T., 2019, In: Diabetologia. 62, 11, p. 2066-2078 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Effects of insulin therapy on weight gain and fat distribution in the HF/HS-STZ rat model of type 2 diabetes

    Skovsø, S., Damgaard, J., Fels, J. J., Olsen, G. S., Wolf, X. A., Rolin, B. & Holst, Jens Juul, 2015, In: International Journal of Obesity. 39, 10, p. 1531-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Accepted/In press

    Effects of exogenous GIP and GLP-2 on bone turnover in individuals with type 2 diabetes

    Skov-Jeppesen, Kirsa, Christiansen, Charlotte Bayer, Hansen, L. S., Windeløv, Johanne Agerlin, Hedbäck, N., Gasbjerg, Lærke Smidt, Hindsø, M., Svane, M. S., Madsbad, Sten, Holst, Jens Juul, Rosenkilde, Mette & Hartmann, Bolette, 2024, (Accepted/In press) In: The Journal of clinical endocrinology and metabolism.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Subcutaneous GIP and GLP-2 inhibit nightly bone resorption in postmenopausal women: A preliminary study

    Skov-Jeppesen, Kirsa, Veedfald, Simon, Madsbad, Sten, Holst, Jens Juul, Rosenkilde, Mette & Hartmann, Bolette, 2021, In: Bone. 152, 7 p., 116065.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    The antiresorptive effect of GIP, but not GLP-2, is preserved in patients with hypoparathyroidism - a randomized crossover study

    Skov-Jeppesen, Kirsa, Hepp, N., Oeke, J., Hansen, M. S., Jafari Kermani, Abbas, Svane, M. S., Balenga, N., Olson, J. A., Frost, M., Kassem, Moustapha Saad El-Deen, Madsbad, Sten, Jensen, Jens-Erik Beck, Holst, Jens Juul, Rosenkilde, Mette & Hartmann, Bolette, 2021, In: Journal of Bone and Mineral Research. 36, 8, p. 1448-1458 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    GLP-2 and GIP exert separate effects on bone turnover: A randomized, placebo-controlled, crossover study in healthy young men

    Skov-Jeppesen, Kirsa, Svane, M. S., Martinussen, C., Gabe, M. B. N., Gasbjerg, Lærke Smidt, Veedfald, Simon, Bojsen-Møller, K. N., Madsbad, Sten, Holst, Jens Juul, Rosenkilde, Mette & Hartmann, Bolette, 2019, In: Bone. 125, p. 178-185

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Separate effects of glucagon like peptide-2 (GLP-2) and glucose-dependent insulinotropic polypeptide (GIP) on bone remodelling

    Skov-Jeppesen, Kirsa, Svane, M., Martinussen, C., Gabe, M., Gasbjerg, Lærke Smidt, Madsbad, Sten, Holst, Jens Juul, Rosenkilde, Mette & Hartmann, Bolette, 2018, In: Diabetologia. 61, S1, p. S245-S245 501.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  11. Published

    Glucagon-like peptide-1 (GLP-1): effect on kidney hemodynamics and renin-angiotensin-aldosterone system in healthy men

    Skov, J., Dejgaard, A., Frøkiær, J., Holst, Jens Juul, Jonassen, Thomas, Rittig, S. & Christiansen, J. S., Apr 2013, In: Journal of Clinical Endocrinology and Metabolism. 98, 4, p. E664-71 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Glucagon-like peptide-1: effect on pro-atrial natriuretic peptide in healthy males

    Skov, J., Holst, Jens Juul, Gøtze, J. P., Frøkiær, J. & Christiansen, J. S., 2014, In: Endocrine Connections. 3, 1, p. 11-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Short-term effects of liraglutide on kidney function and vasoactive hormones in type 2 diabetes: a randomized clinical trial

    Skov, J., Pedersen, M., Holst, Jens Juul, Madsen, B., Goetze, Jens P. , Rittig, S., Jonassen, Thomas, Frøkiær, J., Dejgaard, A. & Christiansen, J. S., 22 Feb 2016, In: Diabetes, Obesity and Metabolism Online. 18, 6, p. 581-9 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Differential effects of glucagon-like peptide-1 on microvascular recruitment and glucose metabolism in short- and long-term Insulin resistance

    Sjøberg, K. A., Rattigan, S., Jeppesen, J. F., Lundsgaard, Anne-Marie, Holst, Jens Juul & Kiens, Bente, 2015, In: Journal of Physiology. 593, 9, p. 2185-2198 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    GLP-1 increases microvascular recruitment but not glucose uptake in human and rat skeletal muscle

    Sjøberg, K. A., Holst, Jens Juul, Rattigan, S., Richter, Erik A. & Kiens, Bente, 2014, In: American Journal of Physiology: Endocrinology and Metabolism. 306, 4, p. E355-E362 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    The effect of glucagon-like peptide 1 on cardiovascular risk

    Sivertsen, J., Rosenmeier, J., Holst, Jens Juul & Vilsbøll, T., Apr 2012, In: Nature Reviews Cardiology. 9, 4, p. 209-22 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Exendin-4, but not dipeptidyl peptidase IV inhibition, increases small intestinal mass in GK rats.

    Simonsen, L., Pilgaard, S., Orskov, C., Rosenkilde, Mette, Hartmann, B., Holst, Jens Juul & Deacon, Carolyn F., 2007, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 293, 1, p. G288-95

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Exendin-4, but not glucagon-like peptide-1, is cleared exclusively by glomerular filtration in anaesthetised pigs

    Simonsen, L., Holst, Jens Juul & Deacon, Carolyn F., 2006, In: Diabetologia. 49, 4, p. 706-712 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Inhibition of neutral endopeptidase 24.11 does not potentiate the improvement in glycemic control obtained with dipeptidyl peptidase-4 inhibition in diabetic Goto-Kakizaki rats

    Simonsen, L., Pilgaard, S., Carr, R. D., Kanstrup, A. B., Holst, Jens Juul & Deacon, Carolyn F., 2009, In: Hormone and Metabolic Research. 41, 11, p. 851-3 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    The C-terminal extension of exendin-4 provides additional metabolic stability when added to GLP-1, while there is minimal effect of truncating exendin-4 in anaesthetized pigs

    Simonsen, L., Holst, Jens Juul, Madsen, K. & Deacon, Carolyn F., 10 Feb 2013, In: Regulatory Peptides. 181, 10, p. 17-21 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Exendin-4, but not glucagon-like peptide-1, is cleared exclusively by glomerular filtration in anaesthetised pigs

    Simonsen, L., Holst, Jens Juul & Deacon, Carolyn F., Apr 2006, In: Diabetologia. 49, 4, p. 706-12 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Long-term exendin-4 treatment delays natural deterioration of glycaemic control in diabetic Goto-Kakizaki rats

    Simonsen, L., Pilgaard, S., Orskov, C., Hartmann, Bolette, Holst, Jens Juul & Deacon, Carolyn F., 2009, In: Diabetes, Obesity and Metabolism. 11, 9, p. 884-90 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Intake of Lactobacillus reuteri Improves Incretin and Insulin Secretion in Glucose-Tolerant Humans: A Proof of Concept

    Simon, M., Strassburger, K., Nowotny, B., Kolb, H., Nowotny, P., Burkart, V., Zivehe, F., Hwang, J., Stehle, P., Pacini, G., Hartmann, Bolette, Holst, Jens Juul, MacKenzie, C., Bindels, L. B., Martinez, I., Walter, J., Henrich, B., Schloot, N. C. & Roden, M., 2015, In: Diabetes Care. 38, 10, p. 1827-34 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    The glucagon like peptide-2 'axis': Capacity for production and response following intestinal resection or repair of gastroschisis in infants

    Sigalet, D. L., Lam, V., Brindle, M., Boctor, D., Wallace, L., de Heuval, E., Hartmann, Bolette & Holst, Jens Juul, 2018, In: Journal of Pediatric Surgery. 53, 5, p. 898-904

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Effects of chronic glucagon-like peptide-2 therapy during weaning in neonatal pigs

    Sigalet, D. L., de Heuvel, E., Wallace, L., Bulloch, E., Turner, J., Wales, P. W., Nation, P., Wizzard, P. R., Hartmann, Bolette, Assad, M. & Holst, Jens Juul, 10 Jan 2014, In: Regulatory Peptides. 188, p. 70-80 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Safety and Dosing Study of Glucagon-Like Peptide 2 in Children With Intestinal Failure

    Sigalet, D. L., Brindle, M., Boctor, D., Casey, L., Dicken, B., Butterworth, S., Lam, V., Karnik, V., de Heuvel, E., Hartmann, Bolette & Holst, Jens Juul, 2017, In: Journal of Parenteral and Enteral Nutrition. 41, 5, p. 844-852 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    GLP-2 levels in infants with intestinal dysfunction

    Sigalet, D. L., Martin, G., Meddings, J., Hartman, B. & Holst, Jens Juul, Sep 2004, In: Pediatric Research. 56, 3, p. 371-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    A safety and pharmacokinetic dosing study of glucagon-like peptide 2 in infants with intestinal failure

    Sigalet, D. L., Brindle, M. E., Boctor, D., Dicken, B., Lam, V., Lu, L. S., de Heuvel, E., Hartmann, Bolette & Holst, Jens Juul, 29 Jan 2017, In: Journal of Pediatric Surgery. 52, 5, p. 749-754

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Enteric neural pathways mediate the anti-inflammatory actions of glucagon-like peptide 2

    Sigalet, D. L., Wallace, L. E., Holst, Jens Juul, Martin, G. R., Kaji, T., Tanaka, H. & Sharkey, K. A., Jul 2007, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 293, 1, p. G211-21

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    A pilot study examining the relationship among Crohn disease activity, glucagon-like peptide-2 signalling and intestinal function in pediatric patients

    Sigalet, D. L., Kravarusic, D., Butzner, D., Hartmann, Bolette, Holst, Jens Juul & Meddings, J., Oct 2013, In: Canadian Journal of Gastroenterology. 27, 10, p. 587-92 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    GLP-2 levels in human infants with intestinal dysfunction

    Sigalet, D. L., Martin, G., Meddings, J., Hartmann, B. & Holst, Jens Juul, 2004, In: Pediatric Research. 56, p. 371-376

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Enteric neural pathways mediate the anti-inflammatory actions of glucagon-like peptide 2

    Sigalet, D. L., Wallace, L. E., Holst, Jens Juul, Martin, G. R., Kaji, T., Tanaka, H. & Sharkey, K. A., 2007, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 293, 1, p. G211-G221

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Cerebrovascular changes following administration of gammaglobulins against substance P or calcitonin gene related peptide in monkey with subarachnoid haemorrhage

    Shiokawa, Y., Holst, Jens Juul, Rasmussen, J. T. N., Schmidt, P. & Svendgaard, N., 1993, In: British J. of Neurosurgery. 7, p. 507-518

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Early gradual feeding with bovine colostrum improves gut function and NEC resistance relative to infant formula in preterm pigs

    Shen, René Liang, Thymann, Thomas, Østergaard, M. V., Støy, A. C. F., Krych, Lukasz, Nielsen, Dennis Sandris, Lauridsen, C., Hartmann, Bolette, Holst, Jens Juul, Burrin, D. G. & Sangild, Per Torp, 2015, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 309, 5, p. G310-G323 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Release of PYY from pig intestinal mucosa; luminal and neural regulation

    Sheikh, S. P., Holst, Jens Juul, Ørskov, Cathrine, Ekman, R. & Schwartz, Thue W., Dec 1989, In: Regulatory Peptides. 26, 3, p. 253-66 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    The combination of colesevelam with sitagliptin enhances glycemic control in diabetic ZDF rat model

    Shang, Q., Liu, M. K., Saumoy, M., Holst, Jens Juul, Salen, G. & Xu, G., 2012, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 302, 8, p. G815-23

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Colesevelam improves insulin resistance in a diet-induced obesity (F-DIO) rat model by increasing the release of GLP-1

    Shang, Q., Saumoy, M., Holst, Jens Juul, Salen, G. & Xu, G., 2009, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 298, 3, p. G419-24

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Effects of glucagon-like peptide-1 (GLP-1) on glucose elimination in healthy subjects depends on the pancreatic glucoregulatory hormones.

    Shalev, A., Holst, Jens Juul & Keller, M., 1977, In: European Journal of Clinical Investigation. 27, p. 10-16

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Effects of glucagon-like peptide-1 (7-36amide) on whole body protein metabolism in healthy man.

    Shalev, A., Holst, Jens Juul & Keller, U., 1997, In: European Journal of Clinical Investigation. 27, p. 10-16.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    GLP-1 effect on ß-cell function varies according to diabetes remission status after RYGB

    Shah, A., Prasad, M., Mark, V., Holst, Jens Juul & Laferrère, B., 2022, In: Diabetes, Obesity and Metabolism. 24, 11, p. 2081-2089

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Effects of Gender-Affirming Hormone Therapy on Insulin Sensitivity and Incretin Responses in Transgender People

    Shadid, S., Abosi-Appeadu, K., De Maertelaere, A., Defreyne, J., Veldeman, L., Holst, Jens Juul, Lapauw, B., Vilsbøll, Tina & T'Sjoen, G., 2020, In: Diabetes Care. 43, 2, p. 411-417

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Induction of insulin and islet amyloid polypeptide production in pancreatic islet glucagonoma cells by insulin promoter factor 1

    Serup, P., Jensen, J., Andersen, F. G., Jørgensen, Mette Christine, Blume, N., Holst, Jens Juul & Madsen, O. D., 20 Aug 1996, In: Proceedings of the National Academy of Sciences of the United States of America. 93, 17, p. 9015-20 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Hypoglycemia-associated changes in the electroencephalogram in patients with type 1 diabetes and normal hypoglycemia awareness or unawareness

    Sejling, A., Kjær, T. W., Pedersen-Bjergaard, Ulrik, Diemar, S. S., Frandsen, C. S. S., Hilsted, L., Faber, Jens, Holst, Jens Juul, Tarnow, L., Nielsen, M. N., Remvig, L. S., Thorsteinsson, B. & Juhl, C. B., May 2015, In: Diabetes. 64, 5, p. 1760-9 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Infrared thermographic assessment of changes in skin temperature during hypoglycaemia in patients with type 1 diabetes

    Sejling, A., Lange, Kai, Frandsen, C. S., Diemar, S. S., Tarnow, L., Faber, Jens, Holst, Jens Juul, Hartmann, Bolette, Hilsted, Linda, Kjaer, T. W., Juhl, C. B., Thorsteinsson, B. & Pedersen-Bjergaard, Ulrik, 2015, In: Diabetologia. 58, p. 1898–1906 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Hypoglycemia-Associated EEG Changes Following Antecedent Hypoglycemia in Type 1 Diabetes Mellitus

    Sejling, A., Kjaer, T. W., Pedersen-Bjergaard, Ulrik, Remvig, L. S., Frandsen, C. S., Hilsted, L., Faber, Jens, Holst, Jens Juul, Tarnow, L., Møller, J. S., Nielsen, M. N., Thorsteinsson, B. & Juhl, C. B., Feb 2017, In: Diabetes Technology & Therapeutics. 19, 2, p. 85-90 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Prolonged and enhanced secretion of glucagon-like peptide 1 (7-36 amide) after oral sucrose due to alpha-glucosidase inhibition (acarbose) in Type 2 diabetic patients

    Seifarth, C., Bergmann, J., Holst, Jens Juul, Ritzel, R., Schmiegel, W. & Nauck, M. A., 1998, In: Diabet. Med.. 15, p. 485-491

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    C-cell hyperplasia accompanying thyroid diseases other than medullary carcinoma: an immunocytochemical study by means of antibodies to calcitonin and somatostatin

    Scopsi, L., di Palma, S., Ferrari, C., Holst, Jens Juul & Rehfeld, J. F., 1991, In: Modern Pathology. Vol 4, no.3, p. 297-304

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Acute Effects of Three Different Meal Patterns on Postprandial Metabolism in Older Individuals with a Risk Phenotype for Cardiometabolic Diseases: A Randomized Controlled Crossover Trial

    Schönknecht, Y. B., Crommen, S., Stoffel-Wagner, B., Coenen, M., Fimmers, R., Holst, Jens Juul, Simon, M. C., Stehle, P. & Egert, S., 2020, In: Molecular Nutrition & Food Research. 64, 9, 13 p., 1901035.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Impaired glucagon-like peptide-1-induced insulin secretion in carriers of transcription factor 7-like 2 (TCF7L2) gene polymorphisms

    Schäfer, S. A., Tschritter, O., Machicao, F., Thamer, C., Stefan, N., Gallwitz, B., Holst, Jens Juul, Dekker, J. M., 't Hart, L. M., t'Hart, L. M., Nijpels, G., van Haeften, T. W., Häring, H. U. & Fritsche, A., Dec 2007, In: Diabetologia. 50, 12, p. 2443-50 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Impaired glucose-induced glucagon suppression after partial pancreatectomy

    Schrader, H., Menge, B. A., Breuer, T. G. K., Ritter, P. R., Uhl, W., Schmidt, W. E., Holst, Jens Juul & Meier, J. J., 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 8, p. 2857-63 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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