Jens Juul Holst
Professor
Endocrinology and Metabolism
Blegdamsvej 3
2200 København N.
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Postprandial release of glucagon-like peptide-1, pancreatic glucagon, and insulin after esophageal resection
Miholic, J., Ørskov, C., Holst, Jens Juul, Kotzerke, J. & Pichlmayr, R., 1993, In: Digestion. 54, p. 73-78Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon-like peptide-1 (GLP-1), Entleerung des Magenersatzes und das Dumpingsyndrom nach Gastrektomie
Miholic, J., Ørskov, C., Holst, Jens Juul, Meyer, H. & Pichlmayr, R., 1991, In: Langerbecks Archiv für Chirurgie. (108. Kongress der Deutsch.Gesellsch.Chirurgie. Suppl.1991, p. 430-432Research output: Contribution to journal › Journal article › Research › peer-review
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Gastric emptying of glucose solution and associated plasma concentrations of GLP-1, GIP, and PYY before and after fundoplication
Miholic, J., Hoffmann, M., Holst, Jens Juul, Lenglinger, J., Mittlböck, M., Bergmann, H. & Stacher, G., Feb 2007, In: Surgical Endoscopy. 21, 2, p. 309-14 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dipeptidyl peptidase-4 inhibitors administered in combination with metformin result in an additive increase in the plasma concentration of active GLP-1
Migoya, E. M., Bergeron, R., Miller, J. L., Snyder, R. N. K., Tanen, M., Hilliard, D., Weiss, B., Larson, P., Gutierrez, M., Jiang, G., Liu, F., Pryor, K. A., Yao, J., Zhu, L., Holst, J. J., Deacon, C., Herman, G., Thornberry, N., Amatruda, J., Williams-Herman, D. & 2 others, , 1 Dec 2010, In: Clinical Pharmacology and Therapeutics. 88, 6, p. 801-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Structural and functional development of small intestine in intrauterine growth retarded porcine offspring born to gilts fed diets with differing protein ratios throughout pregnancy
Mickiewicz, M., Zabielski, R., Grenier, B., Le Normand, L., Savary, G., Holst, Jens Juul, Oswald, I. P., Metges, C. C. & Guilloteau, P., 2012, In: Journal of Physiology and Pharmacology. 63, 3, p. 225-39 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Endocrine and Metabolic Insights from Pancreatic Surgery
Mezza, T., Cefalo, C. M. A., Cinti, F., Quero, G., Pontecorvi, A., Alfieri, S., Holst, Jens Juul & Giaccari, A., Oct 2020, In: Trends in Endocrinology and Metabolism. 31, 10, p. 760-772Research output: Contribution to journal › Review › Research › peer-review
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Bile Modulates Secretion of Incretins and Insulin: A Study of Human Extrahepatic Cholestasis
Mezza, T., Moffa, S., Ferraro, P. M., Quero, G., Capece, U., Carfi, A., Cefalo, C. M. A., Cinti, F., Sorice, G. P., Impronta, F., Mari, A., Pontecorvi, A., Alfieri, S., Holst, Jens Juul & Giaccari, A., 2019, In: Journal of Clinical Endocrinology & Metabolism. 104, 7, p. 2685-2694Research output: Contribution to journal › Journal article › Research › peer-review
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Insulin resistance alters islet morphology in nondiabetic humans
Mezza, T., Muscogiuri, G., Sorice, G. P., Clemente, G., Hu, J., Pontecorvi, A., Holst, Jens Juul, Giaccari, A. & Kulkarni, R. N., Mar 2014, In: Diabetes. 63, 3, p. 994-1007 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of the natural sweetener xylitol on gut hormone secretion and gastric emptying in humans: A pilot dose-ranging study
Meyer-Gerspach, A. C., Drewe, J., Verbeure, W., Le Roux, C. W., Dellatorre-Teixeira, L., Rehfeld, Jens Frederik, Holst, Jens Juul, Hartmann, Bolette, Tack, J., Peterli, R., Beglinger, C. & Wölnerhanssen, B. K., 2021, In: Nutrients. 13, 1, 21 p., 174.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular-scale simulation of electroluminescence in a multilayer white organic light-emitting diode
Mesta, M., Carvelli, M., de Vries, R. J., van Eersel, H., van der Holst, J. J. M., Schober, M., Furno, M., Lüssem, B., Leo, K., Loebl, P., Coehoorn, R., Bobbert, P. A. & Holst, Jens Juul, Jul 2013, In: Nature Materials. 12, 7, p. 652-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Neuropeptide Y (NPY) and vasoactive intestinal polypeptide (VIP), but not galanin, are autonomic cotransmitters in the porcine pancreas
Messell, T., Dunning, B. E., Sheikh, S. & Holst, Jens Juul, 1991, In: International Journal of Gastrointestinal Cancer. 10, p. 133-141Research output: Contribution to journal › Journal article › Research › peer-review
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Extrinsic control of the release of galanin and VIP from intrinsic nerves of isolated, perfused, porcine ileum
Messell, T., Harling, H., Poulsen, Steen Seier, Bersani, M. & Holst, Jens Juul, 9 Apr 1992, In: Regulatory Peptides. 38, 3, p. 179-98 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Extrinsic control of the release of galanin and VIP from intrinsic nerves of isolated, perfused porcine ileum
Messel, T., Harling, H., Poulsen, S. S., Bersani, M. & Holst, Jens Juul, 1992, In: Regulatory Peptides. 38, p. 179-198Research output: Contribution to journal › Journal article › Research › peer-review
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Comparisons of leptin, incretins and body composition in obese and lean patients with hypopituitarism and healthy individuals
Mersebach, H., Svendsen, Ole Lander, Holst, Jens Juul, Astrup, A. & Feldt-Rasmussen, Ulla, 2003, In: Clinical Endocrinology. 58, 1, p. 65-71 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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GIP does not potentiate the antidiabetic effects of GLP-1 in hyperglycemic patients with type 2 diabetes
Mentis, N., Vardarli, I., Köthe, L. D., Holst, Jens Juul, Deacon, Carolyn F., Theodorakis, M., Meier, J. J. & Nauck, M. A., 2011, In: Diabetes. 60, 4, p. 1270-1276 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Near-normalization of glycaemic control with glucagon-like peptide-1 receptor agonist treatment combined with exercise in patients with type 2 diabetes
Mensberg, P., Nyby, S., Jørgensen, P. G., Storgaard, H., Jensen, M. T., Sivertsen, J., Holst, Jens Juul, Kiens, Bente, Richter, Erik A., Knop, Filip Krag & Vilsbøll, Tina, 2017, In: Diabetes, Obesity and Metabolism. 19, 2, p. 172-180 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Loss of inverse relationship between pulsatile insulin and glucagon secretion in patients with type 2 diabetes
Menge, B. A., Grüber, L., Jørgensen, S. M., Deacon, Carolyn F., Schmidt, W. E., Veldhuis, J. D., Holst, Jens Juul & Meier, J. J., Aug 2011, In: Diabetes. 60, 8, p. 2160-2168 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Rare Heterozygous Loss-of-Function Variants in the Human GLP-1 Receptor Are Not Associated With Cardiometabolic Phenotypes
Melchiorsen, Josefine Ulrikke, Sørensen, Kimmie Vestergaard, Bork-Jensen, J., Kizilkaya, Hüsün Sheyma, Gasbjerg, Lærke Smidt, Hauser, Alexander Sebastian, Rungby, Jørgen, Sørensen, H. T., Vaag, Allan, Nielsen, J. S., Pedersen, Oluf Borbye, Linneberg, Allan René, Hartmann, Bolette, Gjesing, A. P., Holst, Jens Juul, Hansen, Torben, Rosenkilde, Mette & Grarup, Niels, 2023, In: Journal of Clinical Endocrinology and Metabolism. 108, 11, p. 2821–2833 38 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Absence of a memory effect for the insulinotropic action of glucagon-like peptide 1(GLP-1) in healthy volunteers
Meier, S., Hücking, K., Ritzelt, R., Holst, Jens Juul, Schmiegel, W. H. & Nauck, M. A., 2003, In: Horm Metab Res. 35, p. 551-556Research output: Contribution to journal › Journal article › Research › peer-review
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Absence of a memory effect for the insulinotropic action of glucagon-like peptide 1 (GLP-1) in healthy volunteers
Meier, S., Hücking, K., Ritzel, R., Holst, Jens Juul, Schmiegel, W. H. & Nauck, M. A., Sep 2003, In: Hormone and Metabolic Research. Supplement. 35, 9, p. 551-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Acute effects of linagliptin on intact and total glucagon-like peptide-1 and gastric inhibitory polypeptide levels in insulin-dependent type 2 diabetes patients with and without moderate renal impairment
Meier, J. J., Quast, D. R., Nauck, M. A., Schenker, N., Deacon, Carolyn F., Holst, Jens Juul, Plum-Mörschel, L. & Kapitza, C., 2022, In: Diabetes, Obesity and Metabolism. 24, 5, p. 806-815Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of gastric inhibitory polypeptide on pentagastrin-stimulated gastric acid secretion in patients with type 2 diabetes and healthy controls.
Meier, J. J., Nauck, M. A., Kask, B., Holst, Jens Juul, Deacon, Carolyn F., Schmidt, W. E. & Gallwitz, B., 2006, In: World Journal of Gastroenterology. 12, 12, p. 1874-80 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Impact of exogenous hyperglucagonemia on postprandial concentrations of gastric inhibitory polypeptide and glucagon-like peptide-1 in humans
Meier, J. J., Ritter, P. R., Jacob, A., Menge, B. A., Deacon, Carolyn F., Schmidt, W. E., Nauck, M. A. & Holst, Jens Juul, 1 Aug 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 8, p. 4061-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The glucagon-like peptide-1 metabolite GLP-1-(9-36) amide reduces postprandial glycemia independently of gastric emptying and insulin secretion in humans.
Meier, J. J., Gethmann, A., Nauck, M. A., Götze, O., Schmitz, F., Deacon, Carolyn F., Gallwitz, B., Schmidt, W. E. & Holst, Jens Juul, 2006, In: American Journal of Physiology: Endocrinology and Metabolism. 290, 6, p. E1118-23Research output: Contribution to journal › Journal article › Research › peer-review
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Erythromycin antagonizes the deceleration of gastric emptying by glucagon-like peptide 1 and unmasks its insulinotropic effect in healthy subjects
Meier, J. J., Kemmeries, G., Holst, Jens Juul & Nauck, M. A., Jul 2005, In: Diabetes. 54, 7, p. 2212-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Similar insulin secretory response to a gastric inhibitory polypeptide bolus injection at euglycemia in first-degree relatives of patients with type 2 diabetes and control subjects.
Meier, J. J., Nauck, M. A., Siepmann, N., Greulich, M., Holst, Jens Juul, Deacon, Carolyn F., Schmidt, W. E. & Gallwitz, B., 2003, In: Metabolism - Clinical and Experimental. 52, 12, p. 1579-85 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Gastric inhibitory polypeptide does not inhibit gastric emptying in humans
Meier, J. J., Goetze, O., Anstipp, J., Hagemann, D., Holst, Jens Juul, Schmidt, W. E., Gallwitz, B. & Nauck, M. A., Apr 2004, In: American Journal of Physiology: Endocrinology and Metabolism. 286, 4, p. E621-5Research output: Contribution to journal › Journal article › Research › peer-review
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Normalization of glucose concentrations and deceleration of gastric emptying after solid meals during intravenous glucagon-like peptide 1 in patients with type 2 diabetes
Meier, J. J., Gallwitz, B., Salmen, S., Goetze, O., Holst, Jens Juul, Schmidt, W. E. & Nauck, M. A., Jun 2003, In: The Journal of clinical endocrinology and metabolism. 88, 6, p. 2719-25 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Intravenous glucagon-like peptide 1 normalizes blood glucose after major surgery in patients with type 2 diabetes
Meier, J. J., Weyhe, D., Michaely, M., Senkal, M., Zumtobel, V., Nauck, M. A., Holst, Jens Juul, Schmidt, W. E. & Gallwitz, B., Mar 2004, In: New Horizons (Baltimore). 32, 3, p. 848-51 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon-like peptide 2 stimulates glucagon secretion, enhances lipid absorption, and inhibits gastric acid secretion in humans
Meier, J. J., Nauck, M. A., Pott, A., Heinze, K., Goetze, O., Bulut, K., Schmidt, W. E., Gallwitz, B. & Holst, Jens Juul, Jan 2006, In: Gastroenterology. 130, 1, p. 44-54 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Stimulation of insulin secretion by intravenous bolus injection and continuous infusion of gastric inhibitory polypeptide in patients with type 2 diabetes and healthy control subjects.
Meier, J. J., Gallwitz, B., Kask, B., Deacon, Carolyn F., Holst, Jens Juul, Schmidt, W. E. & Nauck, M. A., 2004, In: Diabetes. 53 Suppl 3, p. S220-4Research output: Contribution to journal › Journal article › Research › peer-review
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The reduction in hepatic insulin clearance after oral glucose is not mediated by gastric inhibitory polypeptide (GIP).
Meier, J. J., Gallwitz, B., Siepmann, N., Holst, Jens Juul, Deacon, Carolyn F., Schmidt, W. E. & Nauck, M. A., 2003, In: Regulatory Peptides. 113, 1-3, p. 95-100 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Reduction of hepatic insulin clearance after oral glucose ingestion is not mediated by glucagon-like peptide 1 or gastric inhibitory polypeptide in humans
Meier, J. J., Holst, Jens Juul, Schmidt, W. E. & Nauck, M. A., Sep 2007, In: American Journal of Physiology: Endocrinology and Metabolism. 293, 3, p. E849-56Research output: Contribution to journal › Journal article › Research › peer-review
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Secretion, degradation, and elimination of glucagon-like peptide 1 and gastric inhibitory polypeptide in patients with chronic renal insufficiency and healthy control subjects.
Meier, J. J., Nauck, M. A., Kranz, D., Holst, Jens Juul, Deacon, Carolyn F., Gaeckler, D., Schmidt, W. E. & Gallwitz, B., 2004, In: Diabetes. 53, 3, p. 654-62 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Gastric inhibitory polypeptide (GIP) does not inhibit gastric emptying in man
Meier, J. M., Goetze, O., Anstipp, J., Hagemann, D., Holst, Jens Juul, Schmidt, W. E., Gallwitz, B. & Nauck, M. A., 2003, In: Am. J. Physiol.. 16, p. E621-E625Research output: Contribution to journal › Journal article › Research › peer-review
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Insulinotropic effect of gastric inhibitory polypeptide (GIP) in women with a history of gestational diabetes
Meier, J. J., Gallwitz, B., Askenas, M., Vollmer, K., Deacon, Carolyn F., Holst, Jens Juul, Schmidt, W. E. & Nauck, M. A., 2005, In: Diabetologia. 48, p. 1872-1881Research output: Contribution to journal › Journal article › Research
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Normalisation of glucose concentrations and deceleration of gastric emptying of solid meals during intravenous glucagon-like peptide-1 (GLP-1) in patients with type 2 diabetes
Meier, J. J., Gallwitz, B., Salmen, S., Goetze, O., Holst, Jens Juul & Schmidt, W. E., 2003, In: J. Clin. Endocrinol. Metab.. 88, p. 2719-2725Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intravenous glucagon-like peptide 1 (GLP-1) normalizes blood glucose after major surgery in patients with type 2 diabetes
Meier, J. J., Weyhe, D., Michaely, M., Senkal, M., Zumtobel, V., Nauck, M. A., Holst, Jens Juul, Schmidt, W. E. & Gallwitz, B., 2004, In: Critical Care Medicine. 32, p. 848-851Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon-like peptide 1 abolishes the postprandial rise in triglyceride concentrations and lowers levels of non-esterified fatty acids in humans
Meier, J. J., Gethmann, A., Gotze, O., Gallwitz, B., Holst, Jens Juul, Schmidt, W. E. & Nauck, M. A., 2006, In: Diabetologia. 49, 3, p. 452-458 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Reduction of hepatic insulin clearance after oral glucose ingestion is not mediated by glucagon-like peptide 1 or gastric inhibitory polypeptide in humans
Meier, J. J., Holst, Jens Juul, Schmidt, W. E. & Nauck, M. A., 2007, In: American Journal of Physiology: Endocrinology and Metabolism. 293, 3, p. E849-E856Research output: Contribution to journal › Journal article › Research › peer-review
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Gastric inhibitory polypeptide (GIP) dose-dependently stimulates glucagon secretion in healthy human subjects at euglycaemia
Meier, J. J., Gallwitz, N., Siepmann, N., Holst, Jens Juul, Deacon, Carolyn F., Schmidt, W. E. & Nauck, M. A., 2003, In: Diabetologia. 46, p. 798-801Research output: Contribution to journal › Journal article › Research › peer-review
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Suppression of glucagon secretion is lower after oral glucose administration than during intravenous glucose administration in human subjects
Meier, J. J., Deacon, Carolyn F., Schmidt, W. E., Holst, Jens Juul & Nauck, M. A., 2007, In: Diabetologia. 50, 4, p. 806-813 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Reduced insulinotropic effect of gastric inhibitory polypeptide in first-degree relatives of patients with type 2 diabetes
Meier, J. J., Huking, K., Holst, Jens Juul, Deacon, Carolyn F., Schmiegel, W. H. & Nauck, M. A., 2001, In: Diabetes. 50, p. 2497-2504Research output: Contribution to journal › Journal article › Research › peer-review
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Erythromycin antagonises the deceleration of gastric emptying by glucagon-like peptide-1 (GLP)-1 and unmasks its insulinotropic effect in healthy subjects
Meier, J. J., Kemmeries, G., Holst, Jens Juul & Nauck, M. A., 2005, In: Diabetes. 54, p. 2212-2218Research output: Contribution to journal › Journal article › Research
- Published
Glucagon-like peptide 2 stimulates glucagon secretion, enhances lipid absorption, and inhibits gastric acid secretion in humans
Meier, J. J., Nauck, M. A., Pott, A., Heinze, K., Goetze, O., Bulut, K., Schmidt, W. E., Gallwitz, B. & Holst, Jens Juul, 2006, In: Today in Medicine. Gastroenterology. 130, 1, p. 44-54 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Stimulation of glucagon secretion and inhibition of gastric acid secretion by glucagon-like peptide-2 (GLP-2) in healthy human subjects
Meier, J., Nauck, M. A., Pott, A., Heinze, K., Götze, O., Bulut, K., Schmidt, W. E., Gallwitz, B. & Holst, Jens Juul, 2006, In: Today in Medicine. Gastroenterology. 130, p. 44-54Research output: Contribution to journal › Journal article › Research
- Published
Glucagon-like peptide 1 abolishes the postprandial rise in triglyceride concentrations and lowers levels of non-esterified fatty acids in humans
Meier, J. J., Gethmann, A., Götze, O., Gallwitz, B., Holst, Jens Juul, Schmidt, W. E. & Nauck, M. A., Mar 2006, In: Diabetologia. 49, 3, p. 452-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Secretion of incretin hormones and the insulinotropic effect of gastric inhibitory polypeptide in women with a history of gestational diabetes
Meier, J. J., Gallwitz, B., Askenas, M., Vollmer, K., Deacon, Carolyn F., Holst, Jens Juul, Schmidt, W. E. & Nauck, M. A., Sep 2005, In: Diabetologia. 48, 9, p. 1872-81 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Gastric inhibitory polypeptide (GIP) dose-dependently stimulates glucagon secretion in healthy human subjects at euglycaemia
Meier, J. J., Gallwitz, B., Siepmann, N., Holst, Jens Juul, Deacon, Carolyn F., Schmidt, W. E. & Nauck, M. A., Jun 2003, In: Diabetologia. 46, 6, p. 798-801 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Parenteral nutrition impairs plasma bile acid and gut hormone responses to mixed meal testing in lean healthy men
Meessen, E. C. E., Bakker, G. J., Nieuwdorp, M., Dallinga-Thie, G. M., Kemper, E. M., Olde Damink, S. W., Romijn, J. A., Hartmann, Bolette, Holst, Jens Juul, Knop, Filip Krag, Groen, A. K., Schaap, F. G. & Soeters, M. R., 2021, In: Clinical Nutrition. 40, 3, p. 1013-1021Research output: Contribution to journal › Journal article › Research › peer-review
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Meal induced gut hormone secretion is altered in aerobically trained compared to sedentary young healthy males
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Copenhagen study of overweight patients with coronary artery disease undergoing low energy diet or interval training: the randomized CUT-IT trial protocol
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Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial
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