Michael J. Davies
Professor
Inflammation, Metabolism and Oxidation
Blegdamsvej 3
2200 København N.
- 2008
Accumulation of zinc in human atherosclerotic lesions correlates with calcium levels but does not protect against protein oxidation
Stadler, N., Stanley, N., Heeneman, S., Vacata, V., Daemen, M. J. A. P., Bannon, P. G., Waltenberger, J. & Davies, Michael J., May 2008, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 28, 5, p. 1024-30 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Identification of plasma proteins that are susceptible to thiol oxidation by hypochlorous acid and N-chloramines
Summers, F. A., Morgan, P. E., Davies, Michael J. & Hawkins, Clare Louise, Sep 2008, In: Chemical Research in Toxicology. 21, 9, p. 1832-40 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Hypochlorous acid oxidizes methionine and tryptophan residues in myoglobin
Szuchman-Sapir, A. J., Pattison, D. I., Ellis, N. A., Hawkins, Clare Louise, Davies, Michael J. & Witting, P. K., 15 Sep 2008, In: Free Radical Biology & Medicine. 45, 6, p. 789-98 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Waiting for diabetes: Perceptions of people with pre-diabetes: A qualitative study
Troughton, J., Jarvis, J., Skinner, Timothy, Robertson, N., Khunti, K. & Davies, Michael J., 1 Jul 2008, In: Patient Education and Counseling. 72, 1, p. 88-93 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
Glycation of low-density lipoprotein results in the time-dependent accumulation of cholesteryl esters and apolipoprotein B-100 protein in primary human monocyte-derived macrophages
Brown, B. E., Rashid, I., van Reyk, D. M. & Davies, Michael J., Mar 2007, In: F E B S Journal. 274, 6, p. 1530-41 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Oxidation and inactivation of SERCA by selective reaction of cysteine residues with amino acid peroxides
Dremina, E. S., Sharov, V. S., Davies, Michael J. & Schöneich, C., Oct 2007, In: Chemical Research in Toxicology. 20, 10, p. 1462-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Inhibition of protein tyrosine phosphatases by amino acid, peptide, and protein hydroperoxides: potential modulation of cell signaling by protein oxidation products
Gracanin, M. & Davies, Michael J., 15 May 2007, In: Free Radical Biology & Medicine. 42, 10, p. 1543-51 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Degradation of matrix glycosaminoglycans by peroxynitrite/peroxynitrous acid: evidence for a hydroxyl-radical-like mechanism
Kennett, E. C. & Davies, Michael J., 15 Apr 2007, In: Free Radical Biology & Medicine. 42, 8, p. 1278-89 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Serum protein oxidation and apolipoprotein CIII levels in people with systemic lupus erythematosus with and without nephritis
Morgan, P. E., Sturgess, A. D., Hennessy, A. & Davies, Michael J., Dec 2007, In: Free Radical Research. 41, 12, p. 1301-12 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The impact of glycation on apolipoprotein A-I structure and its ability to activate lecithin: cholesterol acyltransferase
Nobecourt, E., Davies, Michael J., Brown, B. E., Curtiss, L. K., Bonnet, D. J., Charlton, F., Januszewski, A. S., Jenkins, A. J., Barter, P. J. & Rye, K. -., Mar 2007, In: Diabetologia. 50, 3, p. 643-653 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Reversible binding of kynurenine to lens proteins: potential protection by glutathione in young lenses
Parker, N. R., Korlimbinis, A., Jamie, J. F., Davies, Michael J. & Truscott, R. J. W., Aug 2007, In: Investigative Ophthalmology & Visual Science. 48, 8, p. 3705-13 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Hypochlorous acid-mediated protein oxidation: how important are chloramine transfer reactions and protein tertiary structure?
Pattison, D. I., Hawkins, Clare Louise & Davies, Michael J., 28 Aug 2007, In: Biochemistry. 46, 34, p. 9853-64 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Carnosine and its constituents inhibit glycation of low-density lipoproteins that promotes foam cell formation in vitro
Rashid, I., van Reyk, D. M. & Davies, Michael J., 6 Mar 2007, In: FEBS Letters. 581, 5, p. 1067-70 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
Degradation of extracellular matrix and its components by hypobromous acid
Rees, M. D., McNiven, T. N. & Davies, Michael J., 15 Jan 2007, In: Biochemical Journal. 401, 2, p. 587-96 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Kinetics of hypobromous acid-mediated oxidation of lipid components and antioxidants
Skaff, O., Pattison, D. I. & Davies, Michael J., Dec 2007, In: Chemical Research in Toxicology. 20, 12, p. 1980-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
Sensitizer-mediated photooxidation of histidine residues: evidence for the formation of reactive side-chain peroxides
Agon, V. V., Bubb, W. A., Wright, A., Hawkins, Clare Louise & Davies, Michael J., 15 Feb 2006, In: Free Radical Biology & Medicine. 40, 4, p. 698-710 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
Inhibition of cathepsins and related proteases by amino acid, peptide, and protein hydroperoxides
Headlam, H. A., Gracanin, M., Rodgers, K. J. & Davies, Michael J., 1 May 2006, In: Free Radical Biology & Medicine. 40, 9, p. 1539-48 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Modification of low-density lipoprotein by myeloperoxidase-derived oxidants and reagent hypochlorous acid
Malle, E., Marsche, G., Arnhold, J. & Davies, Michael J., Apr 2006, In: B B A - Reviews on Cancer. 1761, 4, p. 392-415 24 p.Research output: Contribution to journal › Journal article › Research › peer-review
Reactions of myeloperoxidase-derived oxidants with biological substrates: Gaining chemical insight into human inflammatory diseases
Pattison, David & Davies, Michael J., 2006, In: Current Medicinal Chemistry. 13, 27, p. 3271-3290 20 p.Research output: Contribution to journal › Review › Research › peer-review
Actions of ultraviolet light on cellular structures
Pattison, D. I. & Davies, Michael J., 2006, In: E X S. 96, p. 131-57 27 p.Research output: Contribution to journal › Journal article › Research
Evidence for rapid inter- and intramolecular chlorine transfer reactions of histamine and carnosine chloramines: implications for the prevention of hypochlorous-acid-mediated damage
Pattison, D. I. & Davies, Michael J., 4 Jul 2006, In: Biochemistry. 45, 26, p. 8152-62 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Heparan sulfate degradation via reductive homolysis of its N-chloro derivatives
Rees, M. D. & Davies, Michael J., 8 Mar 2006, In: Journal of the American Chemical Society. 128, 9, p. 3085-97 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diabetes education and self-management for ongoing and newly diagnosed (DESMOND): Process modelling of pilot study
Skinner, Timothy, Carey, M. E., Cradock, S., Daly, H., Davies, Michael J., Doherty, Y., Heller, S., Khunti, K. & Oliver, L., 1 Dec 2006, In: Patient Education and Counseling. 64, 1-3, p. 369-377 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Concentrations of iron correlate with the extent of protein, but not lipid, oxidation in advanced human atherosclerotic lesions
Stanley, N., Stadler, N., Bannon, P. G., Woods, A. A. & Davies, Michael J., 1 May 2006, In: Free Radical Biology & Medicine. 40, 9, p. 1636-43 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Effect of side chains on competing pathways for beta-scission reactions of peptide-backbone alkoxyl radicals
Wood, G. P. F., Easton, C. J., Rauk, A., Davies, Michael J. & Radom, L., 31 Aug 2006, In: Journal of Physical Chemistry Part A: Molecules, Spectroscopy, Kinetics, Environment and General Theory. 110, 34, p. 10316-23 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Evidence for inactivation of cysteine proteases by reactive carbonyls via glycation of active site thiols
Zeng, J., Dunlop, R. A., Rodgers, K. J. & Davies, Michael J., 1 Sep 2006, In: Biochemical Journal. 398, 2, p. 197-206 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Protein and low molecular mass thiols as targets and inhibitors of glycation reactions
Zeng, J. & Davies, Michael J., Dec 2006, In: Chemical Research in Toxicology. 19, 12, p. 1668-76 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
Neuroprotectant effects of iso-osmolar D-mannitol to prevent Pacific ciguatoxin-1 induced alterations in neuronal excitability: a comparison with other osmotic agents and free radical scavengers
Birinyi-Strachan, L. C., Davies, Michael J., Lewis, R. J. & Nicholson, G. M., Oct 2005, In: Neuropharmacology. 49, 5, p. 669-86 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glycation of low-density lipoproteins by methylglyoxal and glycolaldehyde gives rise to the in vitro formation of lipid-laden cells
Brown, B. E., Dean, R. T. & Davies, Michael J., Feb 2005, In: Diabetologia. 48, 2, p. 361-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
The oxidative environment and protein damage
Davies, Michael J., 17 Jan 2005, In: B B A - Reviews on Cancer. 1703, 2, p. 93-109 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
Guanine-specific DNA damage induced by gamma-irradiated histone
Furukawa, A., Hiraku, Y., Oikawa, S., Luxford, C., Davies, Michael J. & Kawanishi, S., 15 Jun 2005, In: Biochemical Journal. 388, Pt 3, p. 813-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
Inactivation of protease inhibitors and lysozyme by hypochlorous acid: role of side-chain oxidation and protein unfolding in loss of biological function
Hawkins, Clare Louise & Davies, Michael J., Oct 2005, In: Chemical Research in Toxicology. 18, 10, p. 1600-10 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
The role of aromatic amino acid oxidation, protein unfolding, and aggregation in the hypobromous acid-induced inactivation of trypsin inhibitor and lysozyme
Hawkins, Clare Louise & Davies, Michael J., Nov 2005, In: Chemical Research in Toxicology. 18, 11, p. 1669-77 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
The role of reactive N-bromo species and radical intermediates in hypobromous acid-induced protein oxidation
Hawkins, Clare Louise & Davies, Michael J., 1 Oct 2005, In: Free Radical Biology & Medicine. 39, 7, p. 900-12 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The illness beliefs of people newly diagnosed with type 2 diabetes: results from the DESMOND pilot study
Heller, S., Davies, Michael J., Khunti, K., Skinner, Timothy & James, P., 1 Jan 2005, Diabetologia.Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
Increased levels of serum protein oxidation and correlation with disease activity in systemic lupus erythematosus
Morgan, P. E., Sturgess, A. D. & Davies, Michael J., Jul 2005, In: Arthritis & Rheumatism. 52, 7, p. 2069-79 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Kinetic analysis of the role of histidine chloramines in hypochlorous acid mediated protein oxidation
Pattison, D. I. & Davies, Michael J., 17 May 2005, In: Biochemistry. 44, 19, p. 7378-87 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Oxidation of heparan sulphate by hypochlorite: role of N-chloro derivatives and dichloramine-dependent fragmentation
Rees, M. D., Pattison, D. I. & Davies, Michael J., 1 Oct 2005, In: Biochemical Journal. 391, Pt 1, p. 125-34 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Protein oxidation injury occurs during pediatric cardiopulmonary bypass
Sheil, M. L., Luxford, C., Davies, Michael J., Peat, J. K., Nunn, G. & Celermajer, D. S., Oct 2005, In: Journal of Thoracic and Cardiovascular Surgery. 130, 4, p. 1054-61 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diabetes screening anxiety and beliefs
Skinner, Timothy, Davies, Michael J., Farooqi, A. M., Jarvis, J., Tringham, J. R. & Khunti, K., 1 Nov 2005, In: Diabetic Medicine. 22, 11, p. 1497-1502 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Utility of risk factors when screening for diabetes mellitus
Tringham, J. R., Davies, Michael J., Jarvis, J., Skinner, Timothy, Farooqi, A. M. & Khunti, K., 1 Jan 2005, Diabetes.Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
Evidence for the formation of adducts and S-(carboxymethyl)cysteine on reaction of alpha-dicarbonyl compounds with thiol groups on amino acids, peptides, and proteins
Zeng, J. & Davies, Michael J., Aug 2005, In: Chemical Research in Toxicology. 18, 8, p. 1232-41 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2004
- Published
EPR spin trapping of protein radicals
Davies, Michael J. & Hawkins, Clare Louise, 2004, In: Free Radical Biology & Medicine. 36, 9, p. 1072-86 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reactive species formed on proteins exposed to singlet oxygen
Davies, Michael J., Jan 2004, In: Photochemical & Photobiological Sciences. 3, 1, p. 17-25 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Markers of protein oxidation: different oxidants give rise to variable yields of bound and released carbonyl products
Headlam, H. A. & Davies, Michael J., 2004, In: Free Radical Biology & Medicine. 36, 9, p. 1175-84 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protective mechanisms against peptide and protein peroxides generated by singlet oxygen
Morgan, P. E., Dean, R. T. & Davies, Michael J., 15 Feb 2004, In: Free Radical Biology & Medicine. 36, 4, p. 484-96 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
Protein-bound kynurenine is a photosensitizer of oxidative damage
Parker, N. R., Jamie, J. F., Davies, Michael J. & Truscott, R. J. W., 1 Nov 2004, In: Free Radical Biology & Medicine. 37, 9, p. 1479-89 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kinetic analysis of the reactions of hypobromous acid with protein components: implications for cellular damage and use of 3-bromotyrosine as a marker of oxidative stress
Pattison, D. I. & Davies, Michael J., 27 Apr 2004, In: Biochemistry. 43, 16, p. 4799-809 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypochlorite and superoxide radicals can act synergistically to induce fragmentation of hyaluronan and chondroitin sulphates
Rees, M. D., Hawkins, Clare Louise & Davies, Michael J., 1 Jul 2004, In: Biochemical Journal. 381, Pt 1, p. 175-84 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Direct detection and quantification of transition metal ions in human atherosclerotic plaques: evidence for the presence of elevated levels of iron and copper
Stadler, N., Lindner, R. A. & Davies, Michael J., 2004, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 24, 5, p. 949-54 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 38036205
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Protein oxidation and peroxidation
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Catalytic oxidant scavenging by selenium-containing compounds: Reduction of selenoxides and N-chloramines by thiols and redox enzymes
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Cardiac spheroids as promising in vitro models to study the human heart microenvironment
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