Thomas Mandrup-Poulsen
Professor
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Lysine deacetylases are produced in pancreatic beta cells and are differentially regulated by proinflammatory cytokines
Lundh, M., Christensen, D. P., Rasmussen, D. N., Mascagni, P., Dinarello, C. A., Billestrup, Nils, Grunnet, L. G. & Mandrup-Poulsen, Thomas, 1 Dec 2010, In: Diabetologia. 53, 12, p. 2569-78 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Lysine demethylase inhibition protects pancreatic β cells from apoptosis and improves β-cell function
Backe, M. B., Andersson, J. L., Bacos, K., Christensen, D. P., Hansen, J. B., Dorosz, J. J., Gajhede, Michael, Dahlby, T., Bysani, M., Kristensen, L. H., Ling, C., Olsen, L. & Mandrup-Poulsen, Thomas, 15 Jan 2018, In: Molecular and Cellular Endocrinology. 460, p. 47-56 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mechanisms of pancreatic islet cell destruction. Dose-dependent cytotoxic effect of soluble blood mononuclear cell mediators on isolated islets of Langerhans
Mandrup-Poulsen, Thomas, Bendtzen, K., Nerup, J., Egeberg, J. & Nielsen, Jens Høiriis, May 1986, In: Allergy. 41, 4, p. 250-9 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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MicroRNAs and histone deacetylase inhibition-mediated protection against inflammatory β-cell damage
Vestergaard, A. L., Bang-Berthelsen, C. H., Floyel, T., Stahl, J. L., Christen, L., Sotudeh, F. T., Horskjaer, P. D. H., Frederiksen, K. S., Kofod, F. G., Bruun, C., Berchtold, L. A., Storling, J., Regazzi, R., Kaur, S., Pociot, Flemming & Mandrup-Poulsen, Thomas, 27 Sep 2018, In: PLOS ONE. 13, 9, p. 1-22 22 p., e0203713 .Research output: Contribution to journal › Journal article › Research › peer-review
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MicroRNAs are potential posttranscriptional regulators of Bcl-2 family members after cytokine stimulation in INS-1 cells
Bang-Berthelsen, C. H., Grunnet, L. G., Kutlu, B., Johansson, F., Eizirik, D., Pociot, F. & Mandrup-Poulsen, Thomas, 2008, In: FEBS Journal. 275, Suppl. 1, p. 152-152Research output: Contribution to journal › Journal article › Research › peer-review
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MicroRNAs as regulators of beta-cell function and dysfunction
Osmai, M., Osmai, Y., Bang-Berthelsen, C. H., Pallesen, E. M. H., Vestergaard, A. L., Novotny, G. W., Pociot, Flemming & Mandrup-Poulsen, Thomas, May 2016, In: Diabetes - Metabolism: Research and Reviews (Print Edition). 32, 4, p. 334–349 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mitophagy protects beta cells from inflammatory damage in diabetes
Sidarala, V., Pearson, G. L., Parekh, V. S., Thompson, B., Christen, L., Gingerich, M. A., Zhu, J., Stromer, T., Ren, J., Reck, E. C., Chai, B., Corbett, J. A., Mandrup-Poulsen, Thomas, Satin, L. S. & Soleimanpour, S. A., 2020, In: JCI insight. 5, 24, 15 p., 141138.Research output: Contribution to journal › Journal article › Research › peer-review
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Mixed-meal tolerance test versus glucagon stimulation test for the assessment of beta-cell function in therapeutic trials in type 1 diabetes.
Greenbaum, C. J., Mandrup-Poulsen, Thomas, McGee, P. F., Battelino, T., Haastert, B., Ludvigsson, J., Pozzilli, P., Lachin, J. M., Kolb, H., Type 1 Diabetes Trial Net Research Group, T. 1. D. T. N. R. G. & European C-Peptide Trial Study Group, E. C. T. S. G., 2008, In: Diabetes Care. 31, 10, p. 1966-71 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Multifactorial treatment increases endothelial progenitor cells in patients with type 2 diabetes
Reinhard, H., Jacobsen, P. K., Lajer, M., Pedersen, N., Billestrup, Nils, Mandrup-Poulsen, Thomas, Parving, H. & Rossing, Peter, 1 Oct 2010, In: Diabetologica. 53, 10, p. 2129-33 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mutation analysis of suppressor of cytokine signalling 3, a candidate gene in Type 1 diabetes and insulin sensitivity
Gylvin, T., Nolsøe, R., Hansen, Torben, Nielsen, E. M. D., Bergholdt, R., Karlsen, A. E., Billestrup, Nils, Borch-Johnsen, K., Pedersen, O., Mandrup-Poulsen, Thomas, Nerup, J. & Pociot, Flemming, 1 Jul 2004, In: Diabetologia. 47, 7, p. 1273-7 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Need for Reclassification of Diabetes Secondary to Iron Overload in the ADA and WHO Classifications
Ellervik, Christina, Birgens, H. & Mandrup-Poulsen, Thomas, Jun 2014, In: Diabetes Care. 37, 6, p. e137-e138 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Neuromedin U Does Not Act as a Decretin in Rats
Kuhre, Rune Ehrenreich, Christiansen, Charlotte Bayer, Ghiasi, S. M., Gabe, M. B. N., Skat-Rørdam, P. A., Modvig, Ida Marie, Mandrup-Poulsen, Thomas, Albrechtsen, Reidar, Rosenkilde, Mette, Hartmann, Bolette, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2019, In: Cell Metabolism. 29, 3, p. 719-726.e1-e5 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Nitric oxide contributes to cytokine-induced apoptosis in pancreatic beta cells via potentiation of JNK activity and inhibition of Akt
Størling, Joachim, Binzer, J., Andersson, A., Züllig, R. A., Tonnesen, M., Knudsen, R. L. P., Spinas, G. A., Sandler, S., Billestrup, Nils & Mandrup-Poulsen, Thomas, 1 Oct 2005, In: Diabetologia. 48, 10, p. 2039-50 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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No direct effect of SGLT2 activity on glucagon secretion
Kuhre, Rune Ehrenreich, Ghiasi, S. M., Adriaenssens, A. E., Albrechtsen, Nicolai Jacob Wewer, Andersen, Daniel Bjørklund, Aivazidis, A., Chen, L., Mandrup-Poulsen, Thomas, Ørskov, Cathrine, Gribble, F. M., Reimann, F., Wierup, N., Tyrberg, B. & Holst, Jens Juul, 2019, In: Diabetologia. 62, 6, p. 1011-1023Research output: Contribution to journal › Journal article › Research › peer-review
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Obesity related differences in MCP-1 and adiponectin expression in subcutaneous adipose tissue in cats.
Jensen, Kathrine Stenberg, Novotny, G. W., Mandrup-Poulsen, Thomas & Bjørnvad, Charlotte Reinhard, 2015.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Obesity related differences in MCP-1 and adiponectin expression in subcutaneous adipose tissue in cats.
Jensen, Kathrine Stenberg, Novotny, G. W., Mandrup-Poulsen, Thomas & Bjørnvad, Charlotte Reinhard, 2014.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Obesity-induced changes in gene expression in feline adipose and skeletal muscle tissue
Jensen, Kathrine Stenberg, Novotny, G. W., Lutz, T. A., Mandrup-Poulsen, Thomas & Bjørnvad, Charlotte Reinhard, 2023, In: Journal of Animal Physiology and Animal Nutrition. 107, 5, p. 1262 - 1278Research output: Contribution to journal › Journal article › Research › peer-review
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Oral histone deacetylase inhibitor synergises with T cell targeted immunotherapy to preserve beta cell metabolic function and induce stable remission of new-onset autoimmune diabetes in NOD mice
Besançon, A., Goncalves, T., Valette, F., Dahllöf, M. S., Mandrup-Poulsen, Thomas, Chatenoud, L. & You, S., 1 Feb 2018, In: Diabetologia. 61, 2, p. 389-398 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Over-expression of Follistatin-like 3 attenuates fat accumulation and improves insulin sensitivity in mice
Brandt, C., Hansen, R. H., Hansen, J. B., Olsen, C. H., Galle, P., Mandrup-Poulsen, Thomas, Gehl, Julie, Pedersen, Bente Klarlund & Hojman, P., Feb 2015, In: Metabolism. 64, 2, p. 283-295 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pancreatic beta-cells respond to fuel pressure with an early metabolic switch
Malinowski, R. M., Ghiasi, S. M., Mandrup-Poulsen, Thomas, Meier, S., Lerche, M. H., Ardenkjaer-Larsen, J. H. & Jensen, P. R., 2020, In: Scientific Reports. 10, 1, 11 p., 15413.Research output: Contribution to journal › Journal article › Research › peer-review
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Perspective: Testing failures
Mandrup-Poulsen, Thomas, 2012, In: Nature Study. 485, 7398, p. S17Research output: Contribution to journal › Journal article › Commissioned
Plasma cytokine levels in young and elderly twins: genes versus environment and relation to in vivo insulin action
Grunnet, Louise Groth, Poulsen, P., Pedersen, Bente Klarlund, Mandrup-Poulsen, Thomas & Vaag, A., 1 Feb 2006, In: Diabetologia. 49, 2, p. 343-50 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Poor pregnancy outcome in women with type 2 diabetes
Clausen, Tine Dalsgaard, Mathiesen, E., Ekbom, P., Hellmuth, E., Mandrup-Poulsen, Thomas & Damm, Peter, 2005, In: Diabetes Care. 28, 2, p. 323-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Proinflammatory Cytokines Inhibit TIMP-1 Expression but Induces PAI-1 and CD63 Expression in INS-1 Cells
Hansen, J. B., Brunner, N. & Mandrup-Poulsen, Thomas, 2009.Research output: Contribution to conference › Poster › Research
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Proinflammatory cytokines activate the intrinsic apoptotic pathway in beta-cells
Grunnet, L. G., Aikin, R., Tonnesen, M. F., Paraskevas, S., Blaabjerg, L., Størling, J., Rosenberg, L., Billestrup, Nils, Maysinger, D. & Mandrup-Poulsen, Thomas, 2009, In: Diabetes. 58, 8, p. 1807-15 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 923693
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780
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Tissue inhibitor of matrix metalloproteinase-1 is required for high-fat diet-induced glucose intolerance and hepatic steatosis in mice
Research output: Contribution to journal › Journal article › Research › peer-review
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212
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JNK1 Deficient Insulin-Producing Cells Are Protected against Interleukin-1 beta-Induced Apoptosis Associated with Abrogated Myc Expression
Research output: Contribution to journal › Journal article › Research › peer-review
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199
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A Placebo-Controlled Study on the Effects of the Glucagon-Like Peptide-1 Mimetic, Exenatide, on Insulin Secretion, Body Composition and Adipokines in Obese, Client-Owned Cats
Research output: Contribution to journal › Journal article › Research › peer-review
Published