Thomas Jespersen

Professor

Physiology of circulation, kidney and lung
Blegdamsvej 3, Building: 12-5-08
2200 København N
Denmark
- thojes@sund.ku.dk
- https://bmi.ku.dk/english/research/circulation-kidney-and-lung/jespersen-group/
Phone: +4524805190Mobile: +4524805190

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ORCID: 0000-0001-6575-360X

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Decreased Heart Rate After Dapagliflozin Treatment In Gottingen Minipigs With Chronic Myocardial Infarction
Debes, Karina Poulsdóttir, Lyhne, Mille Kronborg, Hinz, K., Sand, K. P., Rose, V. H., Flethøj, M., Ludvigsen, Trine Pagh, Kirchhoff, J., Jespersen, Thomas, Pedersen, H. D., Møller, J. E. & Olsen, Lisbeth Høier, 2024, In: Journal of Cardiac Failure. 30, 1, p. 267-268
Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
Published
Detection of atrial fibrillation with implantable loop recorders in horses
Buhl, Rikke, Hesselkilde, E. M., Carstensen, Helena, Fenner, Merle Friederike, Jespersen, Thomas, Tfelt-Hansen, Jacob & Sattler, Stefan M, 2021, In: Equine Veterinary Journal. 53, 2, p. 397-403
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Deubiquitylating enzyme USP2 counteracts Nedd4-2-mediated downregulation of KCNQ1 potassium channels
Krzystanek, K., Rasmussen, Hanne Borger, Grunnet, Morten, Staub, O., Olesen, Søren-Peter, Abriel, H. & Jespersen, Thomas, 2012, In: Heart Rhythm. 9, 3, p. 440-8 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Diet-induced pre-diabetes slows cardiac conductance and promotes arrhythmogenesis
Axelsen, L. N., Callø, Kirstine, Braunstein, T. H., Riemann, Mads, Hofgaard, J. P., Liang, B., Jensen, C. F., Olsen, Kristine Boisen, Bartels, Emil Daniel, Baandrup, U., Jespersen, Thomas, Nielsen, L. B., von Holstein-Rathlou, Niels-Henrik & Nielsen, Morten Schak, 14 Jul 2015, In: Cardiovascular Diabetology. 14, 14 p., 87.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Difference in allelic expression of the CLCN1 gene and the possible influence on the myotonia congenita phenotype.
Dunø, M., Colding-Jørgensen, E., Grunnet, Morten, Jespersen, Thomas, Vissing, John & Schwartz, M., 2004, In: European Journal of Human Genetics. 12, 9, p. 738-43 5 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Differential effects of the transient outward K(+) current activator NS5806 in the canine left ventricle
Callø, Kirstine, Soltysinska, E., Jespersen, Thomas, Lundby, Alicia, Antzelevitch, C., Olesen, Søren-Peter & Cordeiro, J. M., 2009, In: Journal of Molecular and Cellular Cardiology. 48, 1, p. 191-200 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Does KCNE5 play a role in long QT syndrome?
Hofman-Bang, J., Jespersen, Thomas, Grunnet, Morten, Larsen, Lars Allan, Andersen, P. S., Kanters, Jørgen K., Kjeldsen, K. & Christiansen, M., 2004, In: Clinica Chimica Acta. 345, 1-2, p. 49-53 4 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Double mutation at the putative protein kinase C phosphorylation sites Thr¹⁵¹ plus Thr³²³ in the mouse leukotrieneD₄ receptor eliminates homologous desensitization
Jørgensen, S. T., Eriksen, H. N., Dausell, J., Jespersen, Thomas, Lambert, Ian Henry & Hoffmann, E. K., 2013, In: Cellular Physiology and Biochemistry. 31, 2-3, p. 366-378 13 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Dual-function vector for protein expression in both mammalian cells and Xenopus laevis oocytes
Jespersen, Thomas, Grunnet, Morten, Angelo, K., Klærke, Dan Arne & Olesen, Poul, 1 Mar 2002, In: BioTechniques. 32, 3, p. 536-8, 540
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Dynein regulates Kv7.4 channel trafficking from the cell membrane
van der Horst, Jennifer, Rognant, Salomé, Abbott, G. W., Ozhathil, Lijo Cherian, Hägglund, Per Mårten, Barrese, V., Chuang, Christine, Jespersen, Thomas, Davies, Michael J., Greenwood, I. A., Gourdon, Pontus Emanuel, Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, 2021, In: Journal of General Physiology. 153, 3, 19 p., e202012760.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Early Systolic Lengthening in Patients With ST-Segment-Elevation Myocardial Infarction: A Novel Predictor of Cardiovascular Events
Brainin, P., Haahr-Pedersen, S., Olsen, F. J., Holm, A. E., Fritz-Hansen, T., Jespersen, Thomas, Gislason, Gunnar Hilmar & Biering-Sørensen, Tor, 2020, In: Journal of the American Heart Association. 9, 3, p. e013835
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Early systolic lengthening in patients with ST-segment elevation myocardial infarction: a novel predictor of cardiovascular events
Brainin, P., Haahr-Pedersen, S., Olsen, F. J., Fritz-Hansen, T., Jespersen, Thomas, Gislason, Gunnar Hilmar & Biering-Sørensen, Tor, 2019, In: European Heart Journal. 40, Suppl. 1, p. 718-718 1 p., 1270 .
Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
Published
Effect of Selective IK,ACh Inhibition by XAF-1407 in an Equine Model of Tachypacing-induced Persistent Atrial Fibrillation (AF)
Jespersen, Thomas, Fenner, Merle Friederike & Buhl, Rikke, 2019, In: Acta Physiologica. 227, S721, p. 96-96
Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
Published
Effect of Selective IK,ACh Inhibition by XAF-1407 in an Equine Model of Tachypacing-induced Persistent Atrial Fibrillation (AF)
Fenner, Merle Friederike, Carstensen, Helena, Nissen, Sarah Dalgas, Hesselkilde, E. Z., Lunddahl, C., Jensen, M. A. H., Loft-Andersen, A. V., Sattler, Stefan M, Platonov, P. G., El-Haou, S., Jackson, C., Tang, R., Kirby, R., Ford, J. W., Schotten, U., Milnes, J. T., Sørensen, U. S., Jespersen, Thomas & Buhl, Rikke, 2020, In: British Journal of Pharmacology. 177, 16, p. 3778-3794
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Effect of flecainide on atrial fibrillatory rate in a large animal model with induced atrial fibrillation
Hesselkilde, E. Z., Carstensen, Helena, Haugaard, M. M., Carlson, J., Pehrson, S., Jespersen, Thomas, Buhl, Rikke & Platonov, P. G., Dec 2017, In: B M C Cardiovascular Disorders. 17, 6 p., 289.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Effect of induced chronic atrial fibrillation on exercise performance in Standardbred trotters
Buhl, Rikke, Carstensen, Helena, Hesselkilde, E. Z., Klein, B. Z., Hougaard, K. M., Ravn, K. B., Loft-Andersen, A. V., Fenner, Merle Friederike, Pipper, C. & Jespersen, Thomas, 2018, In: Journal of Veterinary Internal Medicine. 32, 4, p. 1410-1419 10 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Effect of the antipsychotic drug haloperidol on arrhythmias during acute myocardial infarction in a porcine model
Sattler, Stefan M, Lubberding, Anniek Frederike, Kristensen, C. B., Møgelvang, R., Blanche, Paul Frédéric, Fink-Jensen, Anders, Engstrøm, Thomas, Kääb, S., Jespersen, Thomas & Tfelt-Hansen, Jacob, 2020, In: IJC Heart and Vasculature. 26, 100455.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Effective termination of atrial fibrillation by SK channel inhibition is associated with a sudden organization of fibrillatory conduction
Gatta, G., Sobota, V., Citerni, C., Diness, Jonas Goldin, Sørensen, U. S., Jespersen, Thomas, Bentzen, Bo Hjorth, Zeemering, S., Kuiper, M., Verheule, S., Schotten, U. & Van Hunnik, A., 2021, In: Europace. 23, 11, p. 1847-1859 13 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Effects of dofetilide and ranolazine on atrial fibrillatory rate in a horse model of acutely induced atrial fibrillation
Carstensen, Helena, Hesselkilde, E. Z., Haugaard, M. M., Flethøj, M., Carlson, J., Pehrson, S., Jespersen, Thomas, Platonov, P. G. & Buhl, Rikke, 2019, In: Journal of Cardiovascular Electrophysiology. 30, 4, p. 596-606
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Effects on atrial fibrillation in aged hypertensive rats by Ca(2+)-activated K(+) channel inhibition
Diness, Jonas Goldin, Skibsbye, L., Jespersen, Thomas, Bartels, Emil Daniel, Sørensen, U. S., Hansen, R. S. & Grunnet, Morten, 2011, In: Hypertension. 57, 6, p. 1129-35 7 p.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Efficient non-PCR-mediated overlap extension of PCR fragments by exonuclease "end polishing"
Jespersen, Thomas, Duch, M. R. & Pedersen, F. S., 1 Jul 1997, In: BioTechniques. 23, 1, p. 48, 50, 52
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Electrocardiographic characteristics of trained and untrained standardbred racehorses
Nissen, Sarah Dalgas, Weis, R., Krag-Andersen, E. K., Hesselkilde, E. M., Isaksen, Jonas L., Carstensen, Helena, Kanters, Jørgen K., Dr Linz, Dominik Karl, Sanders, P., Hopster-Iversen, Charlotte, Jespersen, Thomas, Pehrson, S. & Buhl, Rikke, 2022, In: Journal of Veterinary Internal Medicine. 36, 3, p. 1119-1130
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Electrophysiologic effects of the IK1 inhibitor PA-6 are modulated by extracellular potassium in isolated guinea pig hearts
Hoeker, G. S., Skarsfeldt, M. A., Jespersen, Thomas & Poelzing, S., Jan 2017, In: Physiological Reports. 5, 1, 10 p., e13120.
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Enhanced Ca²⁺-Dependent SK-Channel Gating and Membrane Trafficking in Human Atrial Fibrillation
Heijman, J., Zhou, X., Morotti, S., Molina, C. E., Abu-Taha, I. H., Tekook, M., Jespersen, Thomas, Zhang, Y., Dobrev, S., Milting, H., Gummert, J., Karck, M., Kamler, M., El-Armouche, A., Saljic, Arnela, Grandi, E., Nattel, S. & Dobrev, D., 2023, In: Circulation Research. 132, 9, p. E116-E133
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Expression of heterologous genes from an IRES translational cassette in replication competent murine leukemia virus vectors
Jespersen, Thomas, Duch, M. R., Carrasco, M. L., Warming, S. & Pedersen, F. S., 1 Nov 1999, In: Gene. 239, 2, p. 227-35 9 p.
Research output: Contribution to journal › Journal article › Research › peer-review

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1616 downloads
Antiarrhythmic and electrophysiologic effects of flecainide on acutely induced atrial fibrillation in healthy horses
Research output: Contribution to journal › Journal article › Research › peer-review
Published
350 downloads
Termination of Vernakalant-Resistant Atrial Fibrillation by Inhibition of Small-Conductance Ca2+-Activated K+ Channels in Pigs
Research output: Contribution to journal › Journal article › Research › peer-review
Published
329 downloads
Patients with Long QT Syndrome Due to Impaired hERG-encoded Kv11.1 Potassium Channel Have Exaggerated Endocrine Pancreatic and Incretin Function Associated with Reactive Hypoglycemia
Research output: Contribution to journal › Journal article › Research › peer-review
Published