Jens Juul Holst
Professor
Endocrinology and Metabolism
Blegdamsvej 3
2200 København N.
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Impaired incretin effect and fasting hyperglucagonaemia characterizing type 2 diabetic subjects are early signs of dysmetabolism in obesity
Knop, Filip Krag, Aaboe, K., Vilsbøll, Tina, Vølund, A., Holst, Jens Juul, Krarup, T. & Madsbad, Sten, 2012, In: Diabetes, Obesity and Metabolism. 14, 6, p. 500-510 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Impaired incretin-induced amplification of insulin secretion after glucose homeostatic dysregulation in healthy subjects
Hansen, K. B., Vilsbøll, Tina, Bagger, J. I., Holst, Jens Juul & Knop, Filip Krag, 2012, In: Journal of Clinical Endocrinology and Metabolism. 97, 4, p. 1363-70 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Incretin and pancreatic hormone secretion in Caucasian non-diabetic carriers of the TCF7L2 rs7903146 risk T allele
Faerch, K., Pilgaard, K., Knop, Filip Krag, Hansen, Torben, Pedersen, Oluf Borbye, Jørgensen, T. & Holst, Jens Juul, 2012, In: Diabetes, Obesity and Metabolism Online. 15, 1, p. 91-95 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Incretin based therapies: do they hold their promise?
Holst, Jens Juul, 2012, In: Journal of Diabetes. 4, 1, p. 4-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Incretin hormones in patients with type 2 diabetes are increased by diet-oil, a pro-drug for the GPR 119 receptor agonist, 2-oleoyl-glycerol
Mandoe, M. J., Hansen, K. B., Knop, Filip Krag, Holst, Jens Juul & Hansen, Harald S., Oct 2012, In: Diabetologia. 55, p. S340-S340Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Intestinal adaptation is stimulated by partial enteral nutrition supplemented with the prebiotic short-chain fructooligosaccharide in a neonatal intestinal failure piglet model
Barnes, J. L., Hartmann, Bolette, Holst, Jens Juul & Tappenden, K. A., Sep 2012, In: Journal of Parenteral and Enteral Nutrition. 36, 5, p. 524-37 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Leptin og dens betydning for vægtvedligeholdelse
Iepsen, E. P. W., Torekov, Signe Sørensen & Holst, Jens Juul, 2012, In: Klinisk biokemi i Norden. 24, 4, p. 8-15 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Linagliptin increases incretin levels, lowers glucagon, and improves glycemic control in type 2 diabetes mellitus
Rauch, T., Graefe-Mody, U., Deacon, Carolyn F., Ring, A., Holst, Jens Juul, Woerle, H., Dugi, K. A. & Heise, T., Nov 2012, In: Diabetes Therapy. 3, 1, p. 10Research output: Contribution to journal › Journal article › Research › peer-review
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Linagliptin, a selective DPP-4 inhibitor, inhibits DPP-4, increases incretin levels, lowers glucagon, and improves glycaemic control in patients with Type 2 diabetes.
Rauch, T., Graefe-Mody, U., Deacon, Carolyn F., Ring, A., Holst, Jens Juul, Woerle, H., Dugi, K. & Heise, T., 2012, In: Diabetes Therapy. 3, 1, p. 10Research output: Contribution to journal › Journal article › Research › peer-review
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Mechanisms for the antihyperglycemic effect of sitagliptin in patients with type 2 diabetes
Muscelli, E., Casolaro, A., Gastaldelli, A., Mari, A., Seghieri, G., Astiarraga, B., Chen, Y., Alba, M., Holst, Jens Juul & Ferrannini, E., Aug 2012, In: Journal of Clinical Endocrinology and Metabolism. 97, 8, p. 2818-26 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mechanisms of improved glycaemic control after Roux-en-Y gastric bypass
Dirksen, C., Jørgensen, N. B., Bojsen-Møller, K. N., Jacobsen, S. H., Hansen, D. L., Worm, Dorte, Holst, Jens Juul & Madsbad, Sten, 2012, In: Diabetologia. 55, 7, p. 1890-901 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Metabolic effects of short-term GLP-1 treatment in insulin resistant heart failure patients
Nielsen, R., Wiggers, H., Halbirk, M., Bøtker, H., Holst, Jens Juul, Schmitz, O., Frandsen, E. R., Nielsen, S., Møller, N. & Nørrelund, H., 2012, In: Experimental and Clinical Endocrinology and Diabetes. 120, 5, p. 266-72 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular mechanisms of lipoapoptosis and metformin protection in GLP-1 secreting cells
Kappe, C., Holst, Jens Juul, Zhang, Q. & Sjöholm, A., 12 Oct 2012, In: Biochemical and Biophysical Research Communications. 427, 1, p. 91-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Potential new approaches to modifying intestinal GLP-1 secretion in patients with type 2 diabetes mellitus: focus on bile acid sequestrants
Holst, Jens Juul & McGill, M. A., 2012, In: Clinical Drug Investigation. 32, 1, p. 1-14 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Prolonged successful therapy for hyperinsulinaemic hypoglycaemia after gastric bypass: the pathophysiological role of GLP1 and its response to a somatostatin analogue
Myint, K. S., Greenfield, J. R., Farooqi, I. S., Henning, E., Holst, Jens Juul & Finer, N., 2012, In: European Journal of Endocrinology. 166, 5, p. 951-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Propionate absorbed from the colon acts as gluconeogenic substrate in a strict carnivore, the domestic cat (Felis catus)
Verbrugghe, A., Hesta, M., Daminet, S., Polis, I., Holst, Jens Juul, Buyse, J., Wuyts, B. & Janssens, G. P. J., Dec 2012, In: Journal of Animal Physiology and Animal Nutrition (Online). 96, 6, p. 1054-64 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Randomised controlled trial of colostrum to improve intestinal function in patients with short bowel syndrome
Lund, P., Sangild, Per Torp, Aunsholt, L., Hartmann, Bolette, Holst, Jens Juul, Mortensen, J., Mortensen, P. B. & Jeppesen, P. B., 2012, In: European Journal of Clinical Nutrition. 66, 9, p. 1059-1065 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Reduced adipose tissue lymphatic drainage of macromolecules in obese subjects: a possible link between obesity and local tissue inflammation?
Arngrim, N., Simonsen, L., Holst, Jens Juul & Bülow, J., 2012, In: International Journal of Obesity. 37, p. 748-50Research output: Contribution to journal › Journal article › Research › peer-review
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Relationships among tonic and episodic aspects of motivation to eat, gut peptides, and weight before and after bariatric surgery
Bryant, E. J., King, N. A., Falkén, Y., Hellström, P. M., Holst, Jens Juul, Blundell, J. E. & Näslund, E., 12 Oct 2012, In: Surgery for Obesity and Related Diseases.Research output: Contribution to journal › Journal article › Research › peer-review
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Roux-en-Y gastric bypass surgery does not preserve energy expenditure in humans
Schmidt, J. B., Gunvald, L. E., Gregersen, N. T., Pedersen, S. D., Holst, Jens Juul, Hansen, D. L., Worm, Dorte, Madsbad, Sten, Astrup, A. & Sjödin, Anders Mikael, 2012, In: Regulatory Peptides. 177, suppl.1, p. S32 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Satiety scores and satiety hormone response after sucrose-sweetened soft drink compared with isocaloric semi-skimmed milk and with non-caloric soft drink: a controlled trial
Nielsen, M. M., Sparre, A. B., Holst, Jens Juul, Fenger-Grøn, M., Pedersen, S. B., Astrup, A. & Richelsen, B., 2012, In: European Journal of Clinical Nutrition. 66, 4, p. 523-529 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Steroid-induced insulin resistance and impaired glucose tolerance are both associated with a progressive decline of incretin effect in first-degree relatives of patients with type 2 diabetes
Jensen, D. H., Aaboe, K., Henriksen, J. E., Vølund, A., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 2012, In: Diabetologia. 55, 5, p. 1406-16 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Structural and functional development of small intestine in intrauterine growth retarded porcine offspring born to gilts fed diets with differing protein ratios throughout pregnancy
Mickiewicz, M., Zabielski, R., Grenier, B., Le Normand, L., Savary, G., Holst, Jens Juul, Oswald, I. P., Metges, C. C. & Guilloteau, P., 2012, In: Journal of Physiology and Pharmacology. 63, 3, p. 225-39 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The combination of colesevelam with sitagliptin enhances glycemic control in diabetic ZDF rat model
Shang, Q., Liu, M. K., Saumoy, M., Holst, Jens Juul, Salen, G. & Xu, G., 2012, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 302, 8, p. G815-23Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of a very low calorie diet on insulin sensitivity, beta cell function, insulin clearance, incretin hormone secretion, androgen levels and body composition in obese young women
Svendsen, P. F., Jensen, F. K., Holst, Jens Juul, Haugaard, Steen Bendix, Nilas, L. & Madsbad, Sten, Sep 2012, In: Scandinavian Journal of Clinical & Laboratory Investigation. 72, 5, p. 410-9 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4207
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Meal induced gut hormone secretion is altered in aerobically trained compared to sedentary young healthy males
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Copenhagen study of overweight patients with coronary artery disease undergoing low energy diet or interval training: the randomized CUT-IT trial protocol
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Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial
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