Thomas Mandrup-Poulsen

Thomas Mandrup-Poulsen

Professor

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    1. Published

      Effect of Hydrolyzed Infant Formula vs Conventional Formula on Risk of Type 1 Diabetes: The TRIGR Randomized Clinical Trial

      TRIGR Study Group, T. S. G., 2018, In: J A M A: The Journal of the American Medical Association. 319, 1, p. 38-48

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      Hydrolyzed infant formula and early β-cell autoimmunity: a randomized clinical trial

      Knip, M., Åkerblom, H. K., Becker, D., Dosch, H., Dupre, J., Fraser, W., Howard, N., Ilonen, J., Krischer, J. P., Kordonouri, O., Lawson, M. L., Palmer, J. P., Savilahti, E., Vaarala, O., Virtanen, S. M., TRIGR Study Group, T. S. G. & Mandrup-Poulsen, Thomas, 11 Jun 2014, In: JAMA : the journal of the American Medical Association. 311, 22, p. 2279-87 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      An immune origin of type 2 diabetes?

      Kolb, H. & Mandrup-Poulsen, Thomas, 1 Jun 2005, In: Diabetologia. 48, 6, p. 1038-50 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      The global diabetes epidemic as a consequence of lifestyle-induced low-grade inflammation

      Kolb, H. & Mandrup-Poulsen, Thomas, 2009, In: Diabetologia. 53, 1, p. 10-20 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Identification of a type 1 diabetes-associated CD4 promoter haplotype with high constitutive activity

      Kristiansen, O. P., Karlsen, A. E., Larsen, Z. M., Johannesen, Jesper, Pociot, Flemming, Mandrup-Poulsen, Thomas & Danish IDDM Epidemiology and Genetics Group and Danish Study Group of IDDM in Childhood, D. I. E. A. G. G. A. D. S. G. O. I. I. C., 1 Jun 2004, In: Scandinavian Journal of Immunology. 59, 6, p. 582-91 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Interleukin-6 and diabetes: the good, the bad, or the indifferent?

      Kristiansen, O. P. & Mandrup-Poulsen, Thomas, 2005, In: Diabetes. 54 Suppl 2, p. S114-24

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Association of a functional 17beta-estradiol sensitive IL6-174G/C promoter polymorphism with early-onset type 1 diabetes in females

      Kristiansen, O. P., Nolsøe, R. L., Larsen, L., Gjesing, A. M. P., Johannesen, J., Larsen, Z. M. E., Lykkesfeldt, A. E., Karlsen, A. E., Pociot, Flemming, Mandrup-Poulsen, Thomas & DIEGG, D., 15 May 2003, In: Human Molecular Genetics. 12, 10, p. 1101-10 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      No direct effect of SGLT2 activity on glucagon secretion

      Kuhre, Rune Ehrenreich, Ghiasi, S. M., Adriaenssens, A. E., Albrechtsen, Nicolai Jacob Wewer, Andersen, Daniel Bjørklund, Aivazidis, A., Chen, L., Mandrup-Poulsen, Thomas, Ørskov, Cathrine, Gribble, F. M., Reimann, F., Wierup, N., Tyrberg, B. & Holst, Jens Juul, 2019, In: Diabetologia. 62, 6, p. 1011-1023

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Neuromedin U Does Not Act as a Decretin in Rats

      Kuhre, Rune Ehrenreich, Christiansen, Charlotte Bayer, Ghiasi, S. M., Gabe, M. B. N., Skat-Rørdam, P. A., Modvig, Ida Marie, Mandrup-Poulsen, Thomas, Albrechtsen, Reidar, Rosenkilde, Mette, Hartmann, Bolette, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2019, In: Cell Metabolism. 29, 3, p. 719-726.e1-e5 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Direct demonstration of NCAM cis-dimerization and inhibitory effect of palmitoylation using the BRET2 technique

      Kulahin, N., Grunnet, L. G., Lundh, M., Christensen, D. P., Jorgensen, R., Heding, A., Billestrup, Nils, Berezin, V., Bock, E. & Mandrup-Poulsen, Thomas, 3 Jan 2011, In: FEBS Letters. 585, 1, p. 58-64 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Sustained effects of interleukin-1 receptor antagonist treatment in type 2 diabetes

      Larsen, C. M., Faulenbach, M., Vaag, Allan, Ehses, J. A., Donath, M. Y. & Mandrup-Poulsen, Thomas, 2009, In: Diabetes Care. 32, 9, p. 1663-8 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Interleukin-1-receptor antagonist in type 2 diabetes mellitus.

      Larsen, C. M., Faulenbach, M., Vaag, Allan, Vølund, A., Ehses, J. A., Seifert, B., Mandrup-Poulsen, Thomas & Donath, M. Y., 2007, In: New England Journal of Medicine. 356, 15, p. 1517-26 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Growth arrest- and DNA-damage-inducible 45beta gene inhibits c-Jun N-terminal kinase and extracellular signal-regulated kinase and decreases IL-1beta-induced apoptosis in insulin-producing INS-1E cells

      Larsen, C. M., Døssing, M. G., Papa, S., Franzoso, G., Billestrup, Nils & Mandrup-Poulsen, Thomas, 1 May 2006, In: Diabetologia. 49, 5, p. 980-9 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Behandling af diabetes mellitus med biologiske laegemidler.

      Larsen, C. M. & Mandrup-Poulsen, Thomas, 2008, In: Ugeskrift for læger. 170, 24, p. 2134-7 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Interleukin-1 receptorantagonistbehandling af patienter med type 2-diabetes--sekundaerpublikation.

      Larsen, C. M., Faulenbach, M., Vaag, Allan, Vølund, A., Ehses, J., Seifert, B., Mandrup-Poulsen, Thomas & Donath, M., 2007, In: Ugeskrift for læger. 169, 45, p. 3868-71 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Inhibition of histone deacetylases prevents cytokine-induced toxicity in beta cells

      Larsen, L., Tonnesen, M., Ronn, S. G., Størling, Joachim, Jørgensen, S., Mascagni, P., Dinarello, C. A., Billestrup, Nils & Mandrup-Poulsen, Thomas, Apr 2007, In: Diabetologia. 50, 4, p. 779-89 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Inhibition of histone deacetylases prevents cytokine-induced toxicity in beta cells

      Larsen, L., Tonnesen, M. F., Ronn, S. G., Storling, J., Jørgensen, S., Mascagni, P., Dinarello, C. A., Billestrup, N. & Mandrup-Poulsen, Thomas, 2007, In: Diabetologia. 50, 4, p. 779-789 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Extracellular signal-regulated kinase is essential for interleukin-1-induced and nuclear factor kappaB-mediated gene expression in insulin-producing INS-1E cells

      Larsen, L., Størling, Joachim, Darville, M., Eizirik, D. L., Bonny, C., Billestrup, Nils & Mandrup-Poulsen, Thomas, 1 Dec 2005, In: Diabetologia. 48, 12, p. 2582-90 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Use of vitamin D supplements during infancy in an international feeding trial

      Lehtonen, E., Ormisson, A., Nucci, A., Cuthbertson, D., Sorkio, S., Hyytinen, M., Alahuhta, K., Berseth, C., Salonen, M., Taback, S., Franciscus, M., González-Frutos, T., Korhonen, T. E., Lawson, M. L., Becker, D. J., Krischer, J. P., Knip, M., Virtanen, S. M., TRIGR Investigators, T. I. & Mandrup-Poulsen, Thomas, Apr 2014, In: Public Health Nutrition. 17, 4, p. 810-22 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      The oral histone deacetylase inhibitor ITF2357 reduces cytokines and protects islet ß cells in vivo and in vitro

      Lewis, E. C., Blaabjerg, L., Størling, Joachim, Ronn, S. G., Mascagni, P., Dinarello, C. A. & Mandrup-Poulsen, Thomas, May 2011, In: Molecular Medicine. 17, 5-6, p. 369-377 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Age-dependent transition from islet insulin hypersecretion to hyposecretion in mice with the long QT-syndrome loss-of-function mutation Kcnq1-A340V

      Lubberding, Anniek Frederike, Zhang, J., Lundh, M., Nielsen, Thomas Svava, Søndergaard, M. S., Villadsen, M., Skovhøj, E. Z., Boer, G. A., Hansen, J. B., Thomsen, Morten Bækgaard, Treebak, Jonas Thue, Holst, Jens Juul, Kanters, Jørgen K., Mandrup-Poulsen, Thomas, Jespersen, Thomas, Emanuelli, Brice & Torekov, Signe Sørensen, 2021, In: Scientific Reports. 11, 1, 14 p., 12253.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Celebrities in the heart, strangers in the pancreatic beta cell: Voltage-gated potassium channels Kv7.1 and Kv11.1 bridge long QT syndrome with hyperinsulinaemia as well as type 2 diabetes

      Lubberding, Anniek Frederike, Juhl, C. R., Skovhøj, Emil Zeng, Kanters, Jørgen K., Mandrup-Poulsen, Thomas & Torekov, Signe Sørensen, 2022, In: Acta Physiologica. 234, 3, 18 p., 13781.

      Research output: Contribution to journal › Review › Research › peer-review

    23. Published

      Lysine deacetylases are produced in pancreatic beta cells and are differentially regulated by proinflammatory cytokines

      Lundh, M., Christensen, D. P., Rasmussen, D. N., Mascagni, P., Dinarello, C. A., Billestrup, Nils, Grunnet, L. G. & Mandrup-Poulsen, Thomas, 1 Dec 2010, In: Diabetologia. 53, 12, p. 2569-78 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Histone deacetylases 1 and 3 but not 2 mediate cytokine-induced beta cell apoptosis in INS-1 cells and dispersed primary islets from rats and are differentially regulated in the islets of type 1 diabetic children

      Lundh, M., Christensen, D. P., Damgaard Nielsen, M., Richardson, S. J., Dahllöf, M. S., Skovgaard, T., Berthelsen, J., Dinarello, C. A., Stevenazzi, A., Mascagni, P., Grunnet, Louise Groth, Morgan, N. G. & Mandrup-Poulsen, Thomas, 2012, In: Diabetologia. 55, 9, p. 2421-31

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      HDAC3 inhibition rescues pancreatic beta cells from glucolipotoxicity and improves insulin secretion in obese diabetic rats

      Lundh, M., Galbo, T., Wagner, F. F., Christensen, D. P., Walpita, D., Gale, J. P., Zhang, Y., Hooker, J., Shulman, G. I., Mandrup-Poulsen, Thomas, Holson, E. B. & Wagner, B. K., Sep 2013, In: Diabetologia. 56, 1 suppl, p. S219-S219

      Research output: Contribution to journal › Journal article › Research › peer-review

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    ID: 923693