Jens Juul Holst

Jens Juul Holst

Professor

ORCID: 0000-0001-6853-3805

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  1. Published

    Incretin hormone secretion in women with polycystic ovary syndrome: roles of obesity, insulin sensitivity, and treatment with metformin

    phk294, phk294, Nilas, L., Madsbad, Sten & Holst, Jens Juul, 2009, In: Metabolism - Clinical and Experimental. 58, 5, p. 586-593

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. E-pub ahead of print

    Association between recent exposure to continuous glucose monitoring-recorded hypoglycaemia and counterregulatory and symptom responses to subsequent controlled hypoglycaemia in people with type 1 diabetes

    Svensson, C. H., Fabricius, T. W., Verhulst, C. E. M., Kristensen, Peter Lommer, Tack, C. J., Heller, S. R., Amiel, S. A., McCrimmon, R. J., Evans, M., Holst, Jens Juul, de Galan, B. E. & Pedersen-Bjergaard, Ulrik, 2024, (E-pub ahead of print) In: Diabetes, Obesity and Metabolism.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Relationship between biochemical and symptomatic hypoglycemia after RYGB. Responses to a mixed meal test: a case-control study

    Søeby, M., Nielsen, J. B., Pedersen, S. B., Gribsholt, S. B., Holst, Jens Juul & Richelsen, B., 2020, In: Surgery for Obesity and Related Diseases. 16, 9, p. 1179-1185 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Immunoneutralization of endogenous glucagon reduces hepatic glucose output and improves long-term glycemic control in diabetic ob/ob mice.

    Sørensen, H., Brand, C. L., Neschen, S., Holst, Jens Juul, Fosgerau, K., Nishimura, E. & Shulman, G. I., 2006, In: Diabetes. 55, 10, p. 2843-8 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    No effect of physiological concentrations of glucagon-like peptide-2 on appetite and energy intake in normal weight subjects

    Sørensen, L. B., Flint, A., Raben, Anne, Hartmann, Bolette, Holst, Jens Juul & Astrup, A., Apr 2003, In: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity. 27, 4, p. 450-6 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    No effect of physiological concentrations of glucagon-like peptide-2 on appetite and energy intake in normal weight subjects

    Sørensen, L. B., Flint, A., Raben, A. B., Hartmann, B., Holst, Jens Juul & Astrup, A., 2003, In: International Journal of Obesity. 27, 4, p. 450-456 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    The effect of salatrim, a low-calorie modified triacylglycerol, on appetite and energy intake

    Sørensen, L. B., Cueto, H. T., Andersen, M. T., Bitz, C., Holst, Jens Juul, Rehfeld, Jens Frederik & Astrup, A., 2008, In: American Journal of Clinical Nutrition. 87, 5, p. 1163-1169 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Could the mechanisms of bariatric surgery hold the key for novel therapies? report from a Pennington Scientific Symposium

    Tam, C. S., Berthoud, H., Bueter, M., Chakravarthy, M. V., Geliebter, A., Hajnal, A., Holst, Jens Juul, Kaplan, L., Pories, W., Raybould, H., Seeley, R., Strader, A. & Ravussin, E., Nov 2011, In: Obesity Reviews. 12, 11, p. 984-94 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Impact of the reconstruction method on delayed gastric emptying after pylorus-preserving pancreaticoduodenectomy: a prospective randomized study

    Tamandl, D., Sahora, K., Prucker, J., Schmid, R., Holst, J., Miholic, J., Goetzinger, P., Gnant, M. & Holst, Jens Juul, Feb 2014, In: World Journal of Surgery. 38, 2, p. 465-75 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    The effect of a subcutaneous infusion of GLP-1, OXM and PYY on Energy intake and Expenditure in Obese volunteers

    Tan, T., Behary, P., Tharakan, G., Minnion, J., Al-Najim, W., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul & Bloom, S. R., 1 Jul 2017, In: The Journal of clinical endocrinology and metabolism. 102, 7, p. 2364-2372 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    The arcuate nucleus is pivotal in mediating the anorectic effects of centrally administered leptin

    Tang-Christensen, M., Holst, Jens Juul, Hartmann, B. & Vrang, N., 1999, In: NeuroReport. 10, p. 1183-1187

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    The influence of nutrients, biliary-pancreatic secretions, and systemic trophic hormones on intestinal adaptation in a Roux-en-Y bypass model

    Taqi, E., Wallace, L. E., de Heuvel, E., Chelikani, P. K., Zheng, H., Berthoud, H., Holst, Jens Juul & Sigalet, D. L., 1 May 2010, In: European Journal of Pediatric Surgery. Supplement. 45, 5, p. 987-95 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Role of endogenous incretins in the regulation of postprandial lipoprotein metabolism

    Taskinen, M., Matikainen, N., Björnson, E., Söderlund, S., Ainola, M., Hakkarainen, A., Lundbom, N., Sihlbom, C., Thorsell, A., Andersson, L., Adiels, M., Hartmann, Bolette, Deacon, Carolyn F., Holst, Jens Juul, Packard, C. J. & Borén, J., 2022, In: European Journal of Endocrinology. 187, 1, p. 75-84 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Glucagon-like peptide-2 (GLP-2) increases small intestinal blood flow and mucosal growth in ruminating calves

    Taylor-Edwards, C. C., Burrin, D. G., Holst, Jens Juul, McLeod, K. R. & Harmon, D. L., 2011, In: Journal of Dairy Science. 94, 2, p. 888-898 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Glucagon-like peptide-2 (GLP-2) increases net amino acid utilization by the portal-drained viscera of ruminating calves

    Taylor-Edwards, C. C., Burrin, D. G., Kristensen, N. B., Holst, Jens Juul, McLeod, K. R. & Harmon, D. L., Dec 2012, In: Animal. 6, 12, p. 1985-97 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Expression of mRNA for proglucagon and glucagon-like peptide-2 (GLP-2) receptor in the ruminant gastrointestinal tract and the influence of energy intake

    Taylor-Edwards, C. C., Burrin, D. G., Matthews, J. C., McLeod, K. R., Holst, Jens Juul & Harmon, D. L., 1 Oct 2010, In: Domestic Animal Endocrinology. 39, 3, p. 181-93 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Endogenous GLP-1 mediates postprandial reductions in activation in central reward and satiety areas in patients with type 2 diabetes

    Ten Kulve, J. S., Veltman, D. J., van Bloemendaal, L., Barkhof, F., Deacon, Carolyn F., Holst, Jens Juul, Konrad, R. J., Sloan, J. H., Drent, M. L., Diamant, M. & IJzerman, R. G., Dec 2015, In: Diabetologia. 58, 12, p. 2688-98 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Elevated Postoperative Endogenous GLP-1 Levels Mediate Effects of Roux-en-Y Gastric Bypass on Neural Responsivity to Food Cues

    Ten Kulve, J. S., Veltman, D. J., Gerdes, V. E. A., van Bloemendaal, L., Barkhof, F., Deacon, Carolyn F., Holst, Jens Juul, Drent, M. L., Diamant, M. & IJzerman, R. G., Nov 2017, In: Diabetes Care. 40, 11, p. 1522-1529 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Small molecule ago-allosteric modulators of the human glucagon-like peptide-1 (hGLP-1) receptor

    Teng, M., Johnson, M. D., Thomas, C., Kiel, D., Lakis, J. N., Kercher, T., Aytes, S., Kostrowicki, J., Bhumralkar, D., Truesdale, L., May, J., Sidelman, U., Kodra, J. T., Jørgensen, A. S., Olesen, P. H., Jong, J. C. D., Madsen, P., Behrens, C., Pettersson, I., Knudsen, L. B. & 2 others, Holst, Jens Juul & Lau, J., 2007, In: Bioorganic & Medicinal Chemistry Letters. 17, 19, p. 5472-5478 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    The effects of postprandial exercise and meal glycemic index on plasma glucose and glucoregulatory hormone responses after Roux-en-Y gastric bypass

    Ternhamar, T., Møller, A., Martinussen, C., Svane, M. S., Hindsø, M., Jørgensen, N. B., Dirksen, C., Jensen, Jens-Erik Beck, Hartmann, Bolette, Holst, Jens Juul, Kiens, Bente, Madsbad, Sten & Bojsen-Møller, K. N., 2023, In: American journal of physiology. Endocrinology and metabolism. 325, 5, p. E540-E551 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    The Role of D-allulose and Erythritol on the Activity of the Gut Sweet Taste Receptor and Gastrointestinal Satiation Hormone Release in Humans: A Randomized, Controlled Trial

    Teysseire, F., Bordier, V., Budzinska, A., Weltens, N., Rehfeld, Jens Frederik, Holst, Jens Juul, Hartmann, Bolette, Beglinger, C., Van Oudenhove, L., Wölnerhanssen, B. K. & Meyer-Gerspach, A. C., 2022, In: Journal of Nutrition. 152, 5, p. 1228–1238,

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Roles of increased glycemic variability, GLP-1 and glucagon in hypoglycaemia after Roux-en-Y gastric bypass

    Tharakan, G., Behary, P., Albrechtsen, Nicolai Jacob Wewer, Chahal, H., Kenkre, J., Miras, A. D., Ahmed, A. R., Holst, Jens Juul, Bloom, S. R. & Tan, T. M. M., 1 Dec 2017, In: European Journal of Endocrinology. 177, p. 455-464 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Effects of Pioglitazone on Glucose-Dependent Insulinotropic Polypeptide-Mediated Insulin Secretion and Adipocyte Receptor Expression in Patients With Type 2 Diabetes

    Tharp, W. G., Gupta, D., Sideleva, O., Deacon, Carolyn F., Holst, Jens Juul, Elahi, D. & Pratley, R. E., 2020, In: Diabetes. 69, 2, p. 146-157

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Role of Glucagon in Catabolism and Muscle Wasting of Critical Illness and Modulation by Nutrition

    Thiessen, S. E., Derde, S., Derese, I., Dufour, T., Vega, C. A., Langouche, L., Goossens, C., Peersman, N., Vermeersch, P., Vander Perre, S., Holst, Jens Juul, Wouters, P. J., Vanhorebeek, I. & Van den Berghe, G., 1 Nov 2017, In: American Journal of Respiratory and Critical Care Medicine. 196, 9, p. 1131-1143 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Investigating the roles of hyperglycaemia, hyperinsulinaemia and elevated free fatty acids in cardiac function in patients with type 2 diabetes via treatment with insulin compared with empagliflozin: Protocol for the HyperCarD2 randomised, crossover trial

    Thirumathyam, R., Richter, Erik A., Goetze, Jens P. , Fenger, M., van Hall, Gerrit, Dixen, Ulrik, Holst, Jens Juul, Madsbad, Sten, Vejlstrup, N., Madsen, Per & Jørgensen, N. B., 2022, In: B M J Open. 12, 8, 10 p., e054100.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    The role of empagliflozin-induced metabolic changes for cardiac function in patients with type 2 diabetes. A randomized cross-over magnetic resonance imaging study with insulin as comparator

    Thirumathyam, R., Richter, Erik A., van Hall, Gerrit, Holst, Jens Juul, Fenger, M., Goetze, Jens P. , Dixen, Ulrik, Vejlstrup, N., Madsbad, Sten, Madsen, Per & Jørgensen, N. B., 2024, In: Cardiovascular Diabetology. 23, 1, p. 1-13 13.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Differential effects of saturated and monounsaturated fat on postprandial lipemia and incretin responses in type 2 diabetic subjects

    Thomsen, C., Storm, H., Holst, Jens Juul & Hermansen, K., 2003, In: Am. J. Clin. Nutr.. 77, p. 605-611

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Differential effects of saturated and monounsaturated fat on postprandial lipaemia and GIP/GLP-1 response in healthy subjects

    Thomsen, C., Rasmussen, O., Lousen, T., Hermansen, K. & Holst, Jens Juul, 1999, In: Am. J. Clin. Nutri.. 69, p. 1135-1143

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Differential effects of saturated and monounsaturated fats on postprandial lipemia and glucagon-like peptide 1 responses in patients with type 2 diabetes

    Thomsen, C., Storm, H., Holst, Jens Juul & Hermansen, K., Mar 2003, In: Uden navn. 77, 3, p. 605-11 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    IL-6 has no acute effect on the regulation of urea synthesis in vivo in rats

    Thomsen, K., Aagaard, N. K., Grønbæk, H., Holst, Jens Juul, Jessen, N., Frystyk, J. & Vilstrup, H., Apr 2011, In: Scandinavian Journal of Clinical & Laboratory Investigation. 71, 2, p. 150-156 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Regulation of urea synthesis during the acute-phase response in rats

    Thomsen, K. L., Jessen, N., Møller, A. B., Aagaard, N. K., Grønbæk, H., Holst, Jens Juul & Vilstrup, H., 1 Apr 2013, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 304, 7, p. G680-6 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Reduced carbohydrate and increased protein and fat in the diet augment the positive effect of weight loss on glucose control in type 2 diabetes patients

    Thomsen, M. N., Skytte, M. J., Samkani, A., Carl, M. H., Weber, P., Astrup, A., Larsen, T. M., Frystyk, J., Holst, Jens Juul, Hartmann, Bolette, Thomsen, Henrik S., Chabanova, E., Madsbad, Sten, Haugaard, Steen Bendix & Krarup, T., 2020, In: Diabetologia. 63, Suppl. 1, p. S295-S296 614.

    Research output: Contribution to journal › Conference abstract in journal › Research

  33. Published

    Reduced carbohydrate and increased protein and fat during weight loss improve the atherogenic lipid profile in type 2 diabetes

    Thomsen, M. N., Skytte, M. J., Samkani, A., Astrup, A., Frystyk, J., Chabanova, E., Hartmann, Bolette, Holst, Jens Juul, Larsen, T. M., Madsbad, Sten, Magkos, Faidon, Thomsen, Henrik S., Walzem, R. L., Krarup, T. & Haugaard, Steen Bendix, 2021, In: Diabetologia. 64, SUPPL 1, p. 60-60 109.

    Research output: Contribution to journal › Conference abstract in journal › Research

  34. Published

    The clinical effects of a carbohydrate-reduced high-protein diet on glycaemic variability in metformin-treated patients with type 2 diabetes mellitus: A randomised controlled study

    Thomsen, M. N., fbg982, fbg982, Astrup, A., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten, Krarup, T., Haugaard, Steen Bendix & Samkani, A., 2020, In: Clinical Nutrition ESPEN. 39, p. 46-52 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Weight loss improves β-cell function independently of dietary carbohydrate restriction in people with type 2 diabetes: A 6-week randomized controlled trial

    Thomsen, M. N., Skytte, M. J., Samkani, A., Astrup, A., Fenger, M., Frystyk, J., Hartmann, Bolette, Holst, Jens Juul, Larsen, T. M., Madsbad, Sten, Magkos, Faidon, Rehfeld, Jens Frederik, Haugaard, Steen Bendix & Krarup, T., 2022, In: Frontiers in Nutrition. 9, 14 p., 933118.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Dietary carbohydrate restriction augments weight loss-induced improvements in glycaemic control and liver fat in individuals with type 2 diabetes: A randomised controlled trial

    Thomsen, M. N., Skytte, M. J., Samkani, A., Carl, M. H., Weber, P., Astrup, A., Chabanova, E., Fenger, M., Frystyk, J., Hartmann, Bolette, Holst, Jens Juul, Larsen, T. M., Madsbad, Sten, Magkos, Faidon, Thomsen, Henrik S., Haugaard, Steen Bendix & Krarup, T., 2022, In: Diabetologia. 65, p. 506-517 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Long-term outcomes of dietary carbohydrate restriction for HbA1c reduction in type 2 diabetes mellitus are needed. Reply to Kang J and Ma E [letter]

    Thomsen, M. N., Astrup, A., Holst, Jens Juul, Madsbad, Sten, Magkos, Faidon, Haugaard, Steen Bendix & Krarup, T., 2022, In: Diabetologia. 65, 6, p. 1060-1062 3 p.

    Research output: Contribution to journal › Comment/debate › Research

  38. Published

    Effects of glucagon-like peptide 1 analogs on alcohol intake in alcohol-preferring vervet monkeys

    Thomsen, M., Holst, Jens Juul, Molander, A., Linnet, Kristian, Ptito, M. & Fink-Jensen, Anders, Feb 2019, In: Psychopharmacology. 236, 2, p. 603–611

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Glucose-dependent insulinotropic polypeptide promotes lipid deposition in subcutaneous adipocytes in obese type 2 diabetes patients: a maladaptive response

    Thondam, S. K., Daousi, C., Wilding, J. P. H., Holst, Jens Juul, Ameen, G. I., Yang, C., Whitmore, C., Mora, S. & Cuthbertson, D. J., 1 Mar 2017, In: American Journal of Physiology: Endocrinology and Metabolism. 312, 3, p. E224-E233

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Gastrointestinal function and metabolic control after construction of an orthotopic ileal neobladder in bladder cancer.

    Thorstenson, A., Jacobsson, H., Onelöv, E., Holst, Jens Juul, Hellström, P. M. & Kinn, A., 2007, In: Scandinavian Journal of Urology and Nephrology. 41, 1, p. 14-9 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Short-term insulin treatment prevents the diabetogenic action of streptozotocin in rats

    Thulesen, J., Ørskov, Cathrine, Holst, Jens Juul & Poulsen, Steen Seier, Jan 1997, In: Endocrinology. 138, 1, p. 62-68 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Diabetic intestinal growth adaptation and glucagon-like peptide 2 in the rat: effects of dietary fibre

    Thulesen, J., Hartmann, Bolette, Nielsen, C., Holst, Jens Juul & Poulsen, Steen Seier, Nov 1999, In: Gut. 45, 5, p. 672-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Glucagon-like peptide 2 (GLP-2) accelerates the growth of colonic neoplasms in mice

    Thulesen, J., Hartmann, Bolette, Hare, K. J., Kissow, Hannelouise, Ørskov, Cathrine, Holst, Jens Juul & Poulsen, Steen Seier, Aug 2004, In: Gut. 53, 8, p. 1145-1150 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Calcitonin gene-related peptide (CGRP) in the nipple of the rat mammary gland

    Thulesen, J., Rasmussen, T. N., Schmidt, P., Holst, Jens Juul & Poulsen, Steen Seier, Dec 1994, In: Histochemistry. 102, 6, p. 437-444 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Intestinal growth adaptation and glucagon-like peptide 2 in rats with ileal--jejunal transposition or small bowel resection

    Thulesen, J., Hartmann, Bolette, Kissow, Hannelouise, Jeppesen, Palle Bekker, Ørskov, Cathrine, Holst, Jens Juul & Poulsen, Steen Seier, 2001, In: Digestive Diseases and Sciences. 46, 2, p. 379-88 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Potential targets for glucagon-like peptide 2 (GLP-2) in the rat: distribution and binding of i.v. injected (125)I-GLP-2

    Thulesen, J., Hartmann, Bolette, Ørskov, Cathrine, Jeppesen, Palle Bekker, Holst, Jens Juul & Poulsen, Steen Seier, Oct 2000, In: Peptides. 21, 10, p. 1511-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Diabetic Intestinal Growth Adaptation and glucagon-like peptide 2 (GLP-2) in the rat. Effect of dietary fibres

    Thulesen, J., Hartmann, B., Nielsen, C., Holst, Jens Juul & Poulsen, S. S., 1999, In: Gut. 45, p. 672-678

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Intestinal growth adaptation and glucagon-like peptide 2 in rats with ileal-jejunal transposition or small bowel resection

    Thulesen, J., Hartmann, B., Kissow, H., Jeppesen, P. B., Ørskov, Cathrine, Holst, Jens Juul & Poulsen, Steen Seier, 2001, In: Digestive Diseases and Sciences. 46 (2), p. 379-388

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Potential targets for glucagon-like peptide 2 (GLP-2) in the rat: distribution and binding of i.v. injected (125)I-GLP-2

    Thulesen, J., Hartmann, B., Ørskov, Cathrine, Jeppesen, P. B., Holst, Jens Juul & Poulsen, Steen Seier, 2000, In: Peptides. 10, p. 1511-1517

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Short term insulin treatment prevents the diabetogenic action of streptozotocin in rats

    Thulesen, J., Ørskov, Cathrine, Holst, Jens Juul & Poulsen, Steen Seier, 1997, In: Endokrinologiya. Vol. 138, No. 1, p. 62-68

    Research output: Contribution to journal › Journal article › Research › peer-review

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