Jens Juul Holst

Jens Juul Holst

Professor

ORCID: 0000-0001-6853-3805

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  1. Published

    The combination of colesevelam with sitagliptin enhances glycemic control in diabetic ZDF rat model

    Shang, Q., Liu, M. K., Saumoy, M., Holst, Jens Juul, Salen, G. & Xu, G., 2012, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 302, 8, p. G815-23

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Colesevelam improves insulin resistance in a diet-induced obesity (F-DIO) rat model by increasing the release of GLP-1

    Shang, Q., Saumoy, M., Holst, Jens Juul, Salen, G. & Xu, G., 2009, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 298, 3, p. G419-24

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Release of PYY from pig intestinal mucosa; luminal and neural regulation

    Sheikh, S. P., Holst, Jens Juul, Ørskov, Cathrine, Ekman, R. & Schwartz, Thue W., Dec 1989, In: Regulatory Peptides. 26, 3, p. 253-66 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Early gradual feeding with bovine colostrum improves gut function and NEC resistance relative to infant formula in preterm pigs

    Shen, René Liang, Thymann, Thomas, Østergaard, M. V., Støy, A. C. F., Krych, Lukasz, Nielsen, Dennis Sandris, Lauridsen, C., Hartmann, Bolette, Holst, Jens Juul, Burrin, D. G. & Sangild, Per Torp, 2015, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 309, 5, p. G310-G323 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Cerebrovascular changes following administration of gammaglobulins against substance P or calcitonin gene related peptide in monkey with subarachnoid haemorrhage

    Shiokawa, Y., Holst, Jens Juul, Rasmussen, J. T. N., Schmidt, P. & Svendgaard, N., 1993, In: British J. of Neurosurgery. 7, p. 507-518

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    GLP-2 levels in human infants with intestinal dysfunction

    Sigalet, D. L., Martin, G., Meddings, J., Hartmann, B. & Holst, Jens Juul, 2004, In: Pediatric Research. 56, p. 371-376

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Enteric neural pathways mediate the anti-inflammatory actions of glucagon-like peptide 2

    Sigalet, D. L., Wallace, L. E., Holst, Jens Juul, Martin, G. R., Kaji, T., Tanaka, H. & Sharkey, K. A., 2007, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 293, 1, p. G211-G221

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Effects of chronic glucagon-like peptide-2 therapy during weaning in neonatal pigs

    Sigalet, D. L., de Heuvel, E., Wallace, L., Bulloch, E., Turner, J., Wales, P. W., Nation, P., Wizzard, P. R., Hartmann, Bolette, Assad, M. & Holst, Jens Juul, 10 Jan 2014, In: Regulatory Peptides. 188, p. 70-80 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Safety and Dosing Study of Glucagon-Like Peptide 2 in Children With Intestinal Failure

    Sigalet, D. L., Brindle, M., Boctor, D., Casey, L., Dicken, B., Butterworth, S., Lam, V., Karnik, V., de Heuvel, E., Hartmann, Bolette & Holst, Jens Juul, 2017, In: Journal of Parenteral and Enteral Nutrition. 41, 5, p. 844-852 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    GLP-2 levels in infants with intestinal dysfunction

    Sigalet, D. L., Martin, G., Meddings, J., Hartman, B. & Holst, Jens Juul, Sep 2004, In: Pediatric Research. 56, 3, p. 371-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    A safety and pharmacokinetic dosing study of glucagon-like peptide 2 in infants with intestinal failure

    Sigalet, D. L., Brindle, M. E., Boctor, D., Dicken, B., Lam, V., Lu, L. S., de Heuvel, E., Hartmann, Bolette & Holst, Jens Juul, 29 Jan 2017, In: Journal of Pediatric Surgery. 52, 5, p. 749-754

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Enteric neural pathways mediate the anti-inflammatory actions of glucagon-like peptide 2

    Sigalet, D. L., Wallace, L. E., Holst, Jens Juul, Martin, G. R., Kaji, T., Tanaka, H. & Sharkey, K. A., Jul 2007, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 293, 1, p. G211-21

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    A pilot study examining the relationship among Crohn disease activity, glucagon-like peptide-2 signalling and intestinal function in pediatric patients

    Sigalet, D. L., Kravarusic, D., Butzner, D., Hartmann, Bolette, Holst, Jens Juul & Meddings, J., Oct 2013, In: Canadian Journal of Gastroenterology. 27, 10, p. 587-92 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    The glucagon like peptide-2 'axis': Capacity for production and response following intestinal resection or repair of gastroschisis in infants

    Sigalet, D. L., Lam, V., Brindle, M., Boctor, D., Wallace, L., de Heuval, E., Hartmann, Bolette & Holst, Jens Juul, 2018, In: Journal of Pediatric Surgery. 53, 5, p. 898-904

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Intake of Lactobacillus reuteri Improves Incretin and Insulin Secretion in Glucose-Tolerant Humans: A Proof of Concept

    Simon, M., Strassburger, K., Nowotny, B., Kolb, H., Nowotny, P., Burkart, V., Zivehe, F., Hwang, J., Stehle, P., Pacini, G., Hartmann, Bolette, Holst, Jens Juul, MacKenzie, C., Bindels, L. B., Martinez, I., Walter, J., Henrich, B., Schloot, N. C. & Roden, M., 2015, In: Diabetes Care. 38, 10, p. 1827-34 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Inhibition of neutral endopeptidase 24.11 does not potentiate the improvement in glycemic control obtained with dipeptidyl peptidase-4 inhibition in diabetic Goto-Kakizaki rats

    Simonsen, L., Pilgaard, S., Carr, R. D., Kanstrup, A. B., Holst, Jens Juul & Deacon, Carolyn F., 2009, In: Hormone and Metabolic Research. 41, 11, p. 851-3 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    The C-terminal extension of exendin-4 provides additional metabolic stability when added to GLP-1, while there is minimal effect of truncating exendin-4 in anaesthetized pigs

    Simonsen, L., Holst, Jens Juul, Madsen, K. & Deacon, Carolyn F., 10 Feb 2013, In: Regulatory Peptides. 181, 10, p. 17-21 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Exendin-4, but not glucagon-like peptide-1, is cleared exclusively by glomerular filtration in anaesthetised pigs

    Simonsen, L., Holst, Jens Juul & Deacon, Carolyn F., Apr 2006, In: Diabetologia. 49, 4, p. 706-12 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Long-term exendin-4 treatment delays natural deterioration of glycaemic control in diabetic Goto-Kakizaki rats

    Simonsen, L., Pilgaard, S., Orskov, C., Hartmann, Bolette, Holst, Jens Juul & Deacon, Carolyn F., 2009, In: Diabetes, Obesity and Metabolism. 11, 9, p. 884-90 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Exendin-4, but not glucagon-like peptide-1, is cleared exclusively by glomerular filtration in anaesthetised pigs

    Simonsen, L., Holst, Jens Juul & Deacon, Carolyn F., 2006, In: Diabetologia. 49, 4, p. 706-712 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Exendin-4, but not dipeptidyl peptidase IV inhibition, increases small intestinal mass in GK rats.

    Simonsen, L., Pilgaard, S., Orskov, C., Rosenkilde, Mette, Hartmann, B., Holst, Jens Juul & Deacon, Carolyn F., 2007, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 293, 1, p. G288-95

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    The effect of glucagon-like peptide 1 on cardiovascular risk

    Sivertsen, J., Rosenmeier, J., Holst, Jens Juul & Vilsbøll, T., Apr 2012, In: Nature Reviews Cardiology. 9, 4, p. 209-22 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Differential effects of glucagon-like peptide-1 on microvascular recruitment and glucose metabolism in short- and long-term Insulin resistance

    Sjøberg, K. A., Rattigan, S., Jeppesen, J. F., Lundsgaard, Anne-Marie, Holst, Jens Juul & Kiens, Bente, 2015, In: Journal of Physiology. 593, 9, p. 2185-2198 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    GLP-1 increases microvascular recruitment but not glucose uptake in human and rat skeletal muscle

    Sjøberg, K. A., Holst, Jens Juul, Rattigan, S., Richter, Erik A. & Kiens, Bente, 2014, In: American Journal of Physiology: Endocrinology and Metabolism. 306, 4, p. E355-E362 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Short-term effects of liraglutide on kidney function and vasoactive hormones in type 2 diabetes: a randomized clinical trial

    Skov, J., Pedersen, M., Holst, Jens Juul, Madsen, B., Goetze, Jens P. , Rittig, S., Jonassen, Thomas, Frøkiær, J., Dejgaard, A. & Christiansen, J. S., 22 Feb 2016, In: Diabetes, Obesity and Metabolism Online. 18, 6, p. 581-9 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Glucagon-like peptide-1 (GLP-1): effect on kidney hemodynamics and renin-angiotensin-aldosterone system in healthy men

    Skov, J., Dejgaard, A., Frøkiær, J., Holst, Jens Juul, Jonassen, Thomas, Rittig, S. & Christiansen, J. S., Apr 2013, In: Journal of Clinical Endocrinology and Metabolism. 98, 4, p. E664-71 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Glucagon-like peptide-1: effect on pro-atrial natriuretic peptide in healthy males

    Skov, J., Holst, Jens Juul, Gøtze, J. P., Frøkiær, J. & Christiansen, J. S., 2014, In: Endocrine Connections. 3, 1, p. 11-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Separate effects of glucagon like peptide-2 (GLP-2) and glucose-dependent insulinotropic polypeptide (GIP) on bone remodelling

    Skov-Jeppesen, Kirsa, Svane, M., Martinussen, C., Gabe, M., Gasbjerg, Lærke Smidt, Madsbad, Sten, Holst, Jens Juul, Rosenkilde, Mette & Hartmann, Bolette, 2018, In: Diabetologia. 61, S1, p. S245-S245 501.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  29. Published

    Effects of exogenous GIP and GLP-2 on bone turnover in individuals with type 2 diabetes

    Skov-Jeppesen, Kirsa, Christiansen, Charlotte Bayer, Hansen, L. S., Windeløv, Johanne Agerlin, Hedbäck, N., Gasbjerg, Lærke Smidt, Hindsø, M., Svane, M. S., Madsbad, Sten, Holst, Jens Juul, Rosenkilde, Mette & Hartmann, Bolette, 2024, In: The Journal of clinical endocrinology and metabolism. 109, 7, p. 1773–1780

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Subcutaneous GIP and GLP-2 inhibit nightly bone resorption in postmenopausal women: A preliminary study

    Skov-Jeppesen, Kirsa, Veedfald, Simon, Madsbad, Sten, Holst, Jens Juul, Rosenkilde, Mette & Hartmann, Bolette, 2021, In: Bone. 152, 7 p., 116065.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    The antiresorptive effect of GIP, but not GLP-2, is preserved in patients with hypoparathyroidism - a randomized crossover study

    Skov-Jeppesen, Kirsa, Hepp, N., Oeke, J., Hansen, M. S., Jafari Kermani, Abbas, Svane, M. S., Balenga, N., Olson, J. A., Frost, M., Kassem, Moustapha Saad El-Deen, Madsbad, Sten, Jensen, Jens-Erik Beck, Holst, Jens Juul, Rosenkilde, Mette & Hartmann, Bolette, 2021, In: Journal of Bone and Mineral Research. 36, 8, p. 1448-1458 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    GLP-2 and GIP exert separate effects on bone turnover: A randomized, placebo-controlled, crossover study in healthy young men

    Skov-Jeppesen, Kirsa, Svane, M. S., Martinussen, C., Gabe, M. B. N., Gasbjerg, Lærke Smidt, Veedfald, Simon, Bojsen-Møller, K. N., Madsbad, Sten, Holst, Jens Juul, Rosenkilde, Mette & Hartmann, Bolette, 2019, In: Bone. 125, p. 178-185

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Effects of insulin therapy on weight gain and fat distribution in the HF/HS-STZ rat model of type 2 diabetes

    Skovsø, S., Damgaard, J., Fels, J. J., Olsen, G. S., Wolf, X. A., Rolin, B. & Holst, Jens Juul, 2015, In: International Journal of Obesity. 39, 10, p. 1531-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    A carbohydrate-reduced high-protein diet improves HbA1c and liver fat content in weight stable participants with type 2 diabetes: a randomised controlled trial

    fbg982, fbg982, Samkani, A., Petersen, A. D., Thomsen, M. N., Astrup, A., Chabanova, E., Frystyk, J., Holst, Jens Juul, Thomsen, Henrik S., Madsbad, Sten, Larsen, T. M., Haugaard, Steen Bendix & Krarup, T., 2019, In: Diabetologia. 62, 11, p. 2066-2078 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Effects of carbohydrate restriction on postprandial glucose metabolism, β-cell function, gut hormone secretion, and satiety in patients with type 2 diabetes

    Skytte, M. J., Samkani, A., Astrup, A., Frystyk, J., Rehfeld, Jens Frederik, Holst, Jens Juul, Madsbad, Sten, Burling, K., Fenger, M., Thomsen, M. N., Larsen, T. M., Krarup, T. & Haugaard, Steen Bendix, 2021, In: American Journal of Physiology: Endocrinology and Metabolism. 320, 1, p. E7-E18 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Effects of a highly controlled carbohydrate-reduced high-protein diet on markers of oxidatively generated nucleic acid modifications and inflammation in weight stable participants with type 2 diabetes: a randomized controlled trial

    Skytte, M. J., Samkani, A., Astrup, A., Larsen, T. M., Frystyk, J., Poulsen, Henrik Enghusen, Henriksen, T., Holst, Jens Juul, Andersen, Ove, Madsbad, Sten, Haugaard, Steen Bendix, Krarup, T. & Larsen, E. L., 2020, In: Scandinavian Journal of Clinical & Laboratory Investigation. 80, 5, p. 401-407 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Appetitregulering: et komplekst system

    Sloth, B. & Holst, Jens Juul, 2008, In: Perspektiv. 1, 8

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Effect of subcutaneous injections of PYY1-36 and PYY3-36 on appetite, ad libitum energy intake, and plasma free fatty acids concentration in obese males

    Sloth, B., Davidsen, L., Holst, Jens Juul, Flint, A. & Astrup, A., 2007, In: American Journal of Physiology: Endocrinology and Metabolism. 293, 2, p. E604-E609

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Effects of low vs. high glycemic index diets on appetite and energy expenditure

    Sloth, B., Krog-Mikkelsen, I., Dimitrov, D., Holst, Jens Juul, Flint, A., Tetens, Inge , Björck, I., Elmstahl, H., Astrup, A. & Raben, A., 2004. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Research

  40. Published

    The effect of a high-MUFA, low-glycaemic index diet and a low-fat diet on appetite and glucose metabolism during a 6-month weight maintenance period

    Sloth, B., Due, A. P., Larsen, T. M., Holst, Jens Juul, Heding, A. & Astrup, A., 2008, In: British Journal of Nutrition. 101, 12, p. 1846-1858 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Appetitregulering: et komplekst system

    Sloth, B. & Holst, Jens Juul, 2008, In: Perspektiv : tidsskrift om ernæring. 1, p. 4-8 5 p.

    Research output: Contribution to journal › Journal article › Communication

  42. Published

    The effect of a high monounsaturated fatty acid, low glycemic index diet and a low fat diet on satiety, appetite regulatory hormones and glucose metabolism during a 6 mo weight maintenance period

    Sloth, B., Due, A. P., Larsen, T. M., Holst, Jens Juul, Heding, A. & Astrup, A., 2008, In: International Journal of Obesity. 32, Suppl. 1, p. S204 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research

  43. Published

    Effects of PYY1-36 and PYY3-36 on appetite, energy intake, energy expenditure, glucose and fat metabolism in obese and lean subjects.

    Sloth, B., Holst, Jens Juul, Flint, A., Gregersen, N. T. & Astrup, A., 2006, In: American Journal of Physiology: Endocrinology and Metabolism. 292, 4, p. E1062-E1068 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    The L-alpha-amino acid receptor GPRC6A is expressed in the islets of Langerhans but is not involved in L-arginine-induced insulin release

    Smajilovic, S., Clemmensen, Christoffer, Johansen, L. D., Wellendorph, Petrine, Holst, Jens Juul, Thams, P. G., Ogo, E. & Bräuner, Hans, 2013, In: Amino Acids. 44, 2, p. 383-390 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Comparative analysis of oral and intraperitoneal glucose tolerance tests in mice

    Small, Lewin Barkla, Ehrlich, Amy M, Iversen, Jo Frøkjær, Ashcroft, Stephen Paul, Trošt, K., Moritz, Thomas, Hartmann, Bolette, Holst, Jens Juul, Treebak, Jonas Thue, Zierath, Juleen R & Barrès, Romain, 2022, In: Molecular Metabolism. 57, 8 p., 101440.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    In Vivo Inhibition of Dipeptidyl Peptidase 4 Allows Measurement of GLP-1 Secretion in Mice

    Smits, Mark, Galsgaard, Katrine Douglas, Jepsen, Sara Lind, Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette & Holst, Jens Juul, 2024, In: Diabetes. 73, 5, p. 671-681

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Endogenous glucagon-like peptide (GLP)-1 as alternative for GLP-1 receptor agonists: Could this work and how?

    Smits, Mark & Holst, Jens Juul, 2023, In: Diabetes/Metabolism Research and Reviews. 39, 8, 17 p., e3699.

    Research output: Contribution to journal › Review › Research › peer-review

  48. Published

    Indole-3-carboxyaldehyde does not reverse the intestinal effects of fiber-free diet in mice

    Smits, Mark, Dreyer, S. I. L., Dal, Jenna Elizabeth Hunt, Drzazga, Anna Katarzyna, Modvig, Ida Marie, Holst, Jens Juul & Kissow, Hannelouise, 2024, In: Frontiers in Endocrinology. 15, 10 p., 1362711.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Examining the effects of hyperglycemia on pancreatic endocrine function in humans: evidence for in vivo glucotoxicity

    Solomon, T. P. J., Knudsen, S. H., Karstoft, K., Winding, K., Holst, Jens Juul & Pedersen, Bente Klarlund, Dec 2012, In: Journal of Clinical Endocrinology and Metabolism. 97, 12, p. 4682-91 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Postprandial gallbladder emptying in patients with type 2 diabetes: potential implications for bile-induced secretion of glucagon-like peptide 1

    Sonne, David Peick, Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Oct 2014, In: European Journal of Endocrinology. 171, 4, p. 407-419 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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