Flemming Dela
Professor
Exercise and Muscle
Blegdamsvej 3
2200 København N.
- 2018
- Published
Effects of 6-month aerobic interval training on skeletal muscle metabolism in middle-aged metabolic syndrome patients
Guadalupe-Grau, A., Fernández-Elías, V. E., Ortega, J. F., Dela, Flemming, Helge, Jørn Wulff & Mora-Rodriguez, R., Feb 2018, In: Scandinavian Journal of Medicine & Science in Sports. 28, 2, p. 585-595 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Obesity leads to impairments in the morphology and organization of human skeletal muscle lipid droplets and mitochondrial networks, which are resolved with gastric bypass surgery-induced improvements in insulin sensitivity
Kristensen, M. D., Petersen, S. M., Møller, Kristina, Lund, Morten Asp Vonsild, Hansen, M., Hansen, C. N., Courraud, J., Helge, Jørn Wulff, Dela, Flemming & Prats Gavalda, Clara, Dec 2018, In: Acta Physiologica (Print). 224, 4, 15 p., e13100 .Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Simvastatin-Induced Insulin Resistance May Be Linked to Decreased Lipid Uptake and Lipid Synthesis in Human Skeletal Muscle: the LIFESTAT Study
Larsen, S., Vigelsø, A., Dandanell, S., Prats Gavalda, Clara, Dela, Flemming & Helge, Jørn Wulff, 2018, In: Journal of Diabetes Research. 2018, 7 p., 9257874 .Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitochondrial respiratory capacity remains stable despite a comprehensive and sustained increase in insulin sensitivity in obese patients undergoing gastric bypass surgery
Lund, M. T., Larsen, Steen, Hansen, M., Courraud, J., Floyd, A. K., Støckel, M., Helge, Jørn Wulff & Dela, Flemming, 1 May 2018, In: Acta Physiologica. 223, 1, p. 1-9 e13032.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
2706 km cycling in 2 weeks: effects on cardiac function in 6 elderly male athletes
Morville, T., Rosenkilde, M., Mattsson, N., Dela, Flemming, Helge, Jørn Wulff & Rasmusen, Hanne K., 2018, In: Physician and Sportsmedicine. 46, 3, p. 263-268 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variation in mitochondrial respiratory capacity and myosin heavy chain composition in repeated muscle biopsies
Sahl, Ronni Eg, Morville, T., Kraunsøe, R., Dela, Flemming, Helge, Jørn Wulff & Larsen, Steen, 1 Sep 2018, In: Analytical Biochemistry. 556, p. 119-124 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-intensity interval training improves insulin sensitivity in older individuals
Søgaard, D., Lund, M. T., Scheuer, C. M., Dehlbaek, M. S., Dideriksen, S. G., Abildskov, C. V., Christensen, K. K., Dohlmann, T. L., Larsen, Steen, Vigelsø, A. H., Dela, Flemming & Helge, Jørn Wulff, Apr 2018, In: Acta Physiologica (Print). 222, 4, e13009.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Initial brain aging: heterogeneity of mitochondrial size is associated with decline in complex I-linked respiration in cortex and hippocampus
Thomsen, Kirsten Joan, Yokota, T., Hasan-Olive, M. M., Sherazi, N., Fakouri, N. B., Desler, Claus, Regnell, C. E., Larsen, S., Rasmussen, Lene Juel, Dela, Flemming, Bergersen, L. H. & Lauritzen, Martin, 2018, In: Neurobiology of Aging. 61, p. 215-224 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Peak Fat Oxidation is Not Independently Related to Ironman Performance in Women
Vest, S. D., Frandsen, J., Larsen, S., Dela, Flemming & Helge, Jørn Wulff, 2018, In: International Journal of Sports Medicine. 39, 12, p. 916-923Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
GIP-induced vasodilation in human adipose tissue involves capillary recruitment
Asmar, M., Asmar, A., Simonsen, L., Dela, Flemming, Holst, Jens Juul & Bulow, J., Jun 2019, In: Endocrine Connections. 8, 6, p. 806-813Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Copenhagen Consensus statement 2019: Physical activity and ageing
Bangsbo, J., Blackwell, J., Boraxbekk, C-J., Caserotti, P., Dela, F., Evans, A. B., Jespersen, A. P., Gliemann, L., Kramer, A. F., Lundbye-Jensen, J., Mortensen, E. L., Lassen, A. J., Gow, A. J., Harridge, S. D. R., Hellsten, Y., Kjær, M., Kujala, U. M., Rhodes, R. E., Pike, E. C. J., Skinner, T. & 6 others, , 2019, In: British Journal of Sports Medicine. 53, 14, p. 856-858 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of one-legged high-intensity interval training on insulin-mediated skeletal muscle glucose homeostasis in patients with type 2 diabetes
Dela, Flemming, Ingersen, Arthur, Andersen, N. B., Nielsen, M. B., Petersen, H. H. H., Hansen, C. N., Larsen, Steen, Wojtaszewski, Jørgen F P & Helge, Jørn Wulff, 2019, In: Acta Physiologica (Print). 226, 2, 18 p., e13245.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Trajectories of cardio-metabolic health in successful aging
Dela, Flemming, Finkenzeller, T., Ingersen, Arthur, Poetzelsberger, B. & Mueller, E., 2019, In: Scandinavian Journal of Medicine & Science in Sports. 29, p. 44-51Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Statin Treatment Decreases Mitochondrial Respiration But Muscle Coenzyme Q10 Levels Are Unaltered: The LIFESTAT Study
Dohlmann, T. L., Morville, T., Kuhlman, A. B., Chrøis, K. M., Helge, Jørn Wulff, Dela, Flemming & Larsen, Steen, Jul 2019, In: Journal of Clinical Endocrinology and Metabolism. 104, 7, p. 2501–2508Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Aging in high functioning elderly persons: study design and analyses of behavioral and psychological factors
Finkenzeller, T., Poetzelsberger, B., Koesters, A., Wuerth, S., Amesberger, G., Dela, Flemming & Mueller, E., 2019, In: Scandinavian Journal of Medicine & Science in Sports. 29, p. 7-16Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma free fatty acid concentration is closely tied to whole-body peak fat oxidation rate during repeated exercise
Frandsen, J., Vest, S. D., Ritz, C., Larsen, Steen, Dela, Flemming & Helge, Jørn Wulff, 2019, In: Journal of Applied Physiology. 126, 6, p. 1563-1571 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inflammatory biomarkers in patients in Simvastatin treatment: No effect of co-enzyme Q10 supplementation
Hansen, M., Kuhlman, A. C. B., Sahl, Ronni Eg, Kelly, B., Morville, T., Dohlmann, T. L., Chrøis, K. M., Larsen, S., Helge, Jørn Wulff & Dela, Flemming, 2019, In: Cytokine. 113, p. 393-399 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Determination and validation of peak fat oxidation in endurance-trained men using an upper body graded exercise test
Hansen, Mikkel Thunestvedt, Rømer, Tue, Frandsen, J., Larsen, Steen, Dela, Flemming & Helge, Jørn Wulff, 2019, In: Scandinavian Journal of Medicine & Science in Sports. 29, 11, p. 1677-1690Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of Long-Term Physical Activity and Diet on Skin Glycation and Achilles Tendon Structure
Hjerrild, J. N., Wobbe, A., Stausholm, M. B., Larsen, A. E., Josefsen, C. O., Malmgaard-Clausen, N. M., Dela, Flemming, Kjær, Michael, Magnusson, Stig Peter, Hansen, M., Svensson, R. B. & Couppé, C., 22 Jun 2019, In: Nutrients. 11, 6Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Low N-terminal pro-brain natriuretic peptide levels are associated with non-alcoholic fatty liver disease in patients with type 2 diabetes
Johansen, M. L., Schou, Morten, Rasmussen, J., Rossignol, P., Holm, M. R., Chabanova, E., Dela, Flemming, Faber, Jens & Kistorp, Caroline Michaela Nervil, 2019, In: Diabetes & Metabolism. 45, 5, p. 429-435Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of the mineralocorticoid receptor antagonist eplerenone on liver fat and metabolism in patients with type 2 diabetes: A randomized, double-blind, placebo-controlled trial (MIRAD trial)
Johansen, M. L., Schou, Morten, Rossignol, P., Holm, M. R., Rasmussen, J., Brandt, N., Frandsen, M., Chabanova, E., Dela, Flemming, Faber, Jens & Kistorp, Caroline Michaela Nervil, 2019, In: Diabetes, Obesity and Metabolism. 21, 10, p. 2305-2314 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Coenzyme Q10 does not improve peripheral insulin sensitivity in statin-treated men and women: the LIFESTAT study
Kuhlman, A. B., Morville, T., Dohlmann, T. L., Hansen, M., Kelly, B., Helge, Jørn Wulff & Dela, Flemming, 2019, In: Applied Physiology, Nutrition and Metabolism. 44, p. 485–492Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of exercise amount and intensity on long-term weight loss maintenance and skeletal muscle mitochondrial ROS production in humans
Larsen, Steen, Dandanell, S., Kristensen, K. B., Jorgensen, S. D., Dela, Flemming & Helge, Jørn Wulff, 2019, In: Applied Physiology, Nutrition and Metabolism. 44, 9, p. 958-964Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The rise of statins in Denmark: Making the case for a localized approach to the routinization of pharmaceutical prevention of cardiovascular disease
Lau, Sofie Rosenlund, Andersen, John Sahl, Dela, Flemming & Oxlund, Bjarke, 2019, In: BioSocieties. 14, 2, p. 228-250 23 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Aerobic Exercise Performance and Muscle Strength in Statin Users-The LIFESTAT Study
Morville, T., Dohlmann, T. L., Kuhlman, A. B., Sahl, Ronni Eg, Kriegbaum, Margit, Larsen, Steen, Dela, Flemming & Helge, Jørn Wulff, 2019, In: Medicine and Science in Sports and Exercise. 51, 7, p. 1429-1437 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose homeostasis in statin users-The LIFESTAT study
Morville, T., Dohlmann, T., Kuhlman, A. B., Monberg, T., Torp, M., Hartmann, Bolette, Holst, Jens Juul, Larsen, Steen, Helge, Jørn Wulff & Dela, Flemming, 2019, In: Diabetes - Metabolism: Research and Reviews (Print Edition). 35, 3, 9 p., e3110.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impaired mitochondrial oxidative phosphorylation capacity in epicardial adipose tissue is associated with decreased concentration of adiponectin and severity of coronary atherosclerosis
Nakajima, T., Yokota, T., Shingu, Y., Yamada, A., Iba, Y., Ujihira, K., Wakasa, S., Ooka, T., Takada, S., Shirakawa, R., Katayama, T., Furihata, T., Fukushima, A., Matsuoka, R., Nishihara, H., Dela, Flemming, Nakanishi, K., Matsui, Y. & Kinugawa, S., 2019, In: Scientific Reports. 9, 1, 3535.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased oxidation of RNA despite reduced mitochondrial respiration after chronic electroconvulsive stimulation of rat brain tissue
Nielsen, B., Cejvanovic, V., Wortwein, G., Hansen, A. R., Marstal, K. K., Weimann, A., Bjerring, P. N., Dela, Flemming, Poulsen, Henrik Enghusen & Jørgensen, Martin Balslev, 2019, In: Neuroscience Letters. 690, p. 1-5Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitochondrial reactive oxygen species generation in blood cells is associated with disease severity and exercise intolerance in heart failure patients
Shirakawa, R., Yokota, T., Nakajima, T., Takada, S., Yamane, M., Furihata, T., Maekawa, S., Nambu, H., Katayama, T., Fukushima, A., Saito, A., Ishimori, N., Dela, Flemming, Kinugawa, S. & Anzai, T., 2019, In: Scientific Reports. 9, 8 p., 14709.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Muscle-Saturated Bioactive Lipids Are Increased with Aging and Influenced by High-Intensity Interval Training
Søgaard, D., Baranowski, M., Larsen, Steen, Taulo Lund, M., Munk Scheuer, C., Vestergaard Abildskov, C., Greve Dideriksen, S., Dela, Flemming & Helge, Jørn Wulff, 2019, In: International Journal of Molecular Sciences . 20, 5, 1240.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The influence of age and cardiorespiratory fitness on bioactive lipids in muscle
Søgaard, D., Baranowski, M., Dela, Flemming & Helge, Jørn Wulff, 2019, In: The journals of gerontology. Series A, Biological sciences and medical sciences. 74, 6, p. 778-786Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Beta-aminoisobutyric acid is released by contracting human skeletal muscle and lowers insulin release from INS-1 832/3 cells by mediating mitochondrial energy metabolism
Barlow, J. P., Karstoft, K., Vigelsø, A., Gram, M., Helge, Jørn Wulff, Dela, Flemming, Pappan, K., O'Neil, D., Dunn, W. & Solomon, T. P. J., 2020, In: Metabolism open. 7, p. 100053Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No Acute Effects of Exogenous Glucose-Dependent Insulinotropic Polypeptide on Energy Intake, Appetite, or Energy Expenditure When Added to Treatment With a Long-Acting Glucagon-Like Peptide 1 Receptor Agonist in Men With Type 2 Diabetes
Bergmann, N. C., Gasbjerg, Lærke Smidt, Heimbürger, S. M., Krogh, L. S. L., Dela, Flemming, Hartmann, Bolette, Holst, Jens Juul, Jessen, L., Christensen, Mikkel Bring, Vilsbøll, Tina, Lund, A. & Knop, Filip Krag, 2020, In: Diabetes Care. 43, 3, p. 588-596 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitochondrial adaptations to high intensity interval training in older females and males
Chrois, K. M., Dohlmann, T. L., Sogaard, D., Hansen, Camilla Collin, Dela, Flemming, Helge, Jørn Wulff & Larsen, Steen, 2020, In: European Journal of Sport Science. 20, 1, p. 135-145Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acetaminophen toxicity induces mitochondrial complex I inhibition in human liver tissue
Chrøis, K. M., Larsen, Steen, Pedersen, J. S., Rygg, M. O., Boilsen, A. E. B., Bendtsen, Flemming & Dela, Flemming, 2020, In: Basic & Clinical Pharmacology & Toxicology. 126, 1, p. 86-91Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Role of Muscle Protein and Energy Metabolism in Statin-Associated Muscle Symptoms
Dela, Flemming, Mallinson, J. & Greenhaff, P. L., 2020, Statin-Associated Muscle Symptoms. Contemporary Cardiology. Thompson, P. D. & Taylor, B. A. (eds.). Springer, p. 113-120 (Contemporary Cardiology).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Simvastatin improves mitochondrial respiration in peripheral blood cells
Durhuus, J. A., Hansson, Svenja, Morville, T., Kuhlman, A. B., Dohlmann, T. L., Larsen, Steen, Helge, Jørn Wulff, Angleys, M., Muniesa-Vargas, A., Bundgaard, J. R., Hickson, Ian David, Dela, Flemming, Desler, Claus & Rasmussen, Lene Juel, 2020, In: Scientific Reports. 10, 1, 17012.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Menstrual cycle phase does not affect whole body peak fat oxidation rate during a graded exercise test
Frandsen, J., Pistoljevic, N., Quesada, J. P., Amaro-Gahete, F. J., Ritz, C., Larsen, S., Dela, Flemming & Helge, Jørn Wulff, 2020, In: Journal of Applied Physiology. 128, 3, p. 681-687 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reply to Dutheil et al
Frandsen, J., Pistoljevic, N., Quesada, J. P., Amaro-Gahete, F. J., Larsen, Steen, Dela, Flemming & Helge, Jørn Wulff, 2020, In: Journal of applied physiology (Bethesda, Md. : 1985). 129, 1, 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
The effectiveness of body age-based intervention in workplace health promotion: Results of a cohort study on 9851 Danish employees
Husted, Karina Louise Skov, Dandanell, S., Petersen, Janne, Dela, Flemming & Helge, Jørn Wulff, Sep 2020, In: PLoS ONE. 15, 9 September, 14 p., e0239337.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Biological Age Model Designed for Health Promotion Interventions: Protocol for an Interdisciplinary Study for Model Development
Husted, Karina Louise Skov, Fogelstrom, M., Hulst, P., Brink-Kjaer, A., Henneberg, K., Sorensen, H. B. D., Dela, Flemming & Helge, Jørn Wulff, 2020, In: JMIR Research Protocols. 9, 10, 13 p., 19209.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hvad kan vi lære af årtiers kolesteroldebat? kampen om kolesterolet
Lau, Sofie Rosenlund, Andersen, John Sahl, Dela, Flemming & Oxlund, Bjarke, 2020, In: Månedsskrift for praktisk lægegerning. 1, p. 831-838Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The relationship between peak fat oxidation and prolonged double-poling endurance exercise performance
Rømer, Tue, Hansen, Mikkel Thunestvedt, Frandsen, J., Larsen, Steen, Dela, Flemming & Helge, Jørn Wulff, 2020, In: Scandinavian Journal of Medicine & Science in Sports. 30, 11, p. 2044-2056Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitochondrial dysfunction in adults after out-of-hospital cardiac arrest
Wiberg, S., Stride, N., Bro-Jeppesen, J., Holmberg, M. J., Kjærgaard, J., Larsen, Steen, Donnino, M. W., Hassager, Christian & Dela, Flemming, 2020, In: European Heart Journal: Acute Cardiovascular Care. 9, 4, p. S138–S144 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Six weeks of high intensity cycle training reduces H2O2 emission and increases antioxidant protein levels in obese adults with risk factors for type 2 diabetes
Flensted-Jensen, Mathias, Gram, M., Dela, Flemming, Helge, Jørn Wulff & Larsen, Steen, 2021, In: Free Radical Biology & Medicine. 173, p. 1-6Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Maximal fat oxidation rate is higher in fit women and unfit women with obesity, compared to normal weight unfit women
Frandsen, J., Hansen, I. M. D., Wismann, J. F., Olsen, M. H., Brage-Andersen, M. R., Sahl, Ronni Eg, Hansen, M., Ingersen, Arthur, Modvig, J. L., Schmücker, M., brl298, brl298, Dela, Flemming, Larsen, Steen & Helge, Jørn Wulff, 2021, In: Journal of Clinical Endocrinology and Metabolism. 106, 11, p. E4389-E4399 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Peak fat oxidation rate is closely associated with plasma free fatty acid concentrations in women; similar to men
Frandsen, J., Poggi, A. I., Ritz, C., Larsen, S., Dela, Flemming & Helge, Jørn Wulff, 2021, In: Frontiers in Physiology. 12, 11 p., 696261.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The influence of age, sex and cardiorespiratory fitness on maximal fat oxidation rate
Frandsen, J., Amaro-Gahete, F. J., Landgrebe, A., Dela, Flemming, Ruiz, J. R., Helge, Jørn Wulff & Larsen, Steen, 2021, In: Applied Physiology, Nutrition and Metabolism. 46, 10, p. 1241-1247Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The training induced increase in whole-body peak fat oxidation rate may be attenuated with aging
Frandsen, J., Beck, T., Langkilde, C. H., Larsen, Steen, Dela, Flemming & Helge, Jørn Wulff, 2021, In: European Journal of Sport Science. 21, 1, p. 69-76Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exogenous LEAP2 improves postprandial glucose tolerance and reduces ad libitum food intake in men
Hagemann, C. A., Jensen, M. S., Holm, Stephanie Kjærulff, Gasbjerg, Lærke Smidt, Christensen, Mikkel Bring, Heimburger, S. M. N., Dela, Flemming, Vilsbøll, Tina, Holst, Birgitte & Knop, Filip Krag, 2021, In: Diabetologia. 64, SUPPL 1, p. 23-23 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
ID: 10200
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The relationship between skeletal muscle mitochondrial citrate synthase activity and whole body oxygen uptake adaptations in response to exercise training.
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Meal induced gut hormone secretion is altered in aerobically trained compared to sedentary young healthy males
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Two weeks of metformin treatment enhances mitochondrial respiration in skeletal muscle of AMPK kinase dead but not wild type mice
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