Validation of Obstetric Diagnosis and Procedure Codes in the Danish National Patient Registry in 2017
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Validation of Obstetric Diagnosis and Procedure Codes in the Danish National Patient Registry in 2017. / Herskind, Kamille; Jensen, Peter Bjødstrup; Vinter, Christina Anne; Krebs, Lone; Eskildsen, Lene Friis; Broe, Anne; Pottegård, Anton; Bliddal, Mette.
I: Clinical Epidemiology, Bind 16, 2024, s. 121-130.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Validation of Obstetric Diagnosis and Procedure Codes in the Danish National Patient Registry in 2017
AU - Herskind, Kamille
AU - Jensen, Peter Bjødstrup
AU - Vinter, Christina Anne
AU - Krebs, Lone
AU - Eskildsen, Lene Friis
AU - Broe, Anne
AU - Pottegård, Anton
AU - Bliddal, Mette
N1 - Publisher Copyright: © 2024 Herskind et al.
PY - 2024
Y1 - 2024
N2 - Purpose: This study aimed to systematically evaluate the validity of variables related to pregnancy, delivery, and key characteristics of the infant in the Danish National Patient Register using maternal medical records as the reference standard. Patients and Methods: We reviewed medical records of 1264 women giving birth in the Region of Southern Denmark during 2017. We calculated positive (PPV) and negative (NPV) predictive values, sensitivity, and specificity to estimate the validity of 49 selected variables. Results: The PPV was ≥0.90 on most pregnancy-related variables including parity, pre-gestational BMI, diabetes disorders, and previous cesarean section, while it was lower for hypertensive disorders, especially mild to moderate preeclampsia (0.49, 95% CI 0.32–0.66). Sensitivity ranged from 0.80 to 1.00 on all pregnancy-related variables, except hypertensive disorders (sensitivity 0.38– 0.71, lowest for severe preeclampsia). On most delivery-related variables including obstetric surgical procedures (eg cesarean section and induction of labor), pharmacological pain-relief, and gestational age at delivery, PPV’s ranged from 0.98 to 1.00 and the corresponding sensitivities from 0.87 to 1.00. Regarding infant-related variables, both the APGAR score registered five minutes after delivery and birthweight yielded a PPV of 1.00. Conclusion: Obstetric coding in the Danish National Patient Register shows very high validity and completeness making it a valuable source for epidemiologic research.
AB - Purpose: This study aimed to systematically evaluate the validity of variables related to pregnancy, delivery, and key characteristics of the infant in the Danish National Patient Register using maternal medical records as the reference standard. Patients and Methods: We reviewed medical records of 1264 women giving birth in the Region of Southern Denmark during 2017. We calculated positive (PPV) and negative (NPV) predictive values, sensitivity, and specificity to estimate the validity of 49 selected variables. Results: The PPV was ≥0.90 on most pregnancy-related variables including parity, pre-gestational BMI, diabetes disorders, and previous cesarean section, while it was lower for hypertensive disorders, especially mild to moderate preeclampsia (0.49, 95% CI 0.32–0.66). Sensitivity ranged from 0.80 to 1.00 on all pregnancy-related variables, except hypertensive disorders (sensitivity 0.38– 0.71, lowest for severe preeclampsia). On most delivery-related variables including obstetric surgical procedures (eg cesarean section and induction of labor), pharmacological pain-relief, and gestational age at delivery, PPV’s ranged from 0.98 to 1.00 and the corresponding sensitivities from 0.87 to 1.00. Regarding infant-related variables, both the APGAR score registered five minutes after delivery and birthweight yielded a PPV of 1.00. Conclusion: Obstetric coding in the Danish National Patient Register shows very high validity and completeness making it a valuable source for epidemiologic research.
KW - delivery
KW - epidemiology
KW - pregnancy
KW - registries
KW - sensitivity and specificity
KW - validity
U2 - 10.2147/CLEP.S441123
DO - 10.2147/CLEP.S441123
M3 - Journal article
C2 - 38404706
AN - SCOPUS:85185922139
VL - 16
SP - 121
EP - 130
JO - Clinical Epidemiology
JF - Clinical Epidemiology
SN - 1179-1349
ER -
ID: 384479252