uPA binding sites on domain 2+3 on uPAR and antibodies reactive therewith

Publikation: Patent

Standard

uPA binding sites on domain 2+3 on uPAR and antibodies reactive therewith. / Pessara, Ulrich (Opfinder); Weidle, Ulrich (Opfinder); Koenig, Bernhard (Opfinder); Kohnert, Ulrich (Opfinder); Bartke, Ilse (Opfinder); Dano, Keld (Opfinder); Ploug, Michael (Opfinder); Ellis, Vincent (Opfinder).

Patentnummer: EP0691350. jan. 10, 1996.

Publikation: Patent

Harvard

Pessara, U, Weidle, U, Koenig, B, Kohnert, U, Bartke, I, Dano, K, Ploug, M & Ellis, V jan.. 10 1996, uPA binding sites on domain 2+3 on uPAR and antibodies reactive therewith, Patentnummer EP0691350.

APA

Pessara, U., Weidle, U., Koenig, B., Kohnert, U., Bartke, I., Dano, K., Ploug, M., & Ellis, V. (1996). uPA binding sites on domain 2+3 on uPAR and antibodies reactive therewith. (Patentnummer EP0691350).

Vancouver

Pessara, U, Weidle, U, Koenig, B, Kohnert, U, Bartke, I, Dano, K o.a., Opfindere. uPA binding sites on domain 2+3 on uPAR and antibodies reactive therewith. EP0691350. 1996 jan. 10.

Author

Pessara, Ulrich (Opfinder) ; Weidle, Ulrich (Opfinder) ; Koenig, Bernhard (Opfinder) ; Kohnert, Ulrich (Opfinder) ; Bartke, Ilse (Opfinder) ; Dano, Keld (Opfinder) ; Ploug, Michael (Opfinder) ; Ellis, Vincent (Opfinder). / uPA binding sites on domain 2+3 on uPAR and antibodies reactive therewith. Patentnummer: EP0691350. jan. 10, 1996.

Bibtex

@misc{2205665248564cbe9ef34c7c1170a4f3,
title = "uPA binding sites on domain 2+3 on uPAR and antibodies reactive therewith",
abstract = "The invention relates to an antibody which inhibits the binding between u-PA and u-PAR to an extent of at least 90% in an assay as defined in the specification, or an active fragment or immunological equivalent of said antibody. Examples of such antibodies are deposited 7 July 1994 at Deutsche Sammlung von Mikroorganismen und Zellkulturen (DSM) with accession numbers DSM ACC2178 and DSM ACC2179 under the terms and conditions of the Budapest Treaty. The invention furthermore relates to a method for detecting or quantifying u-PAR or a glycosylation variant of u-PAR in a sample by use of an antibody according to the invention. Furthermore, the invention relates to a method for the manufacture of a therapeutic agent for preventing or counteracting localized proteolytic activity using of an antibody of the invention as well as to use of an antibody according to the invention for the preparation of a diagnostic agent which is capable of targeting a diagnostic to a cell that contains a u-PAR on the surface.",
author = "Ulrich Pessara, and Ulrich Weidle, and Bernhard Koenig, and Ulrich Kohnert, and Ilse Bartke, and Keld Dano, and Michael Ploug, and Vincent Ellis,",
year = "1996",
month = jan,
day = "10",
language = "English",
type = "Patent",
note = "EP0691350; C12R 1/ 91 A N",

}

RIS

TY - PAT

T1 - uPA binding sites on domain 2+3 on uPAR and antibodies reactive therewith

AU - Pessara,, Ulrich

AU - Weidle,, Ulrich

AU - Koenig,, Bernhard

AU - Kohnert,, Ulrich

AU - Bartke,, Ilse

AU - Dano,, Keld

AU - Ploug,, Michael

AU - Ellis,, Vincent

PY - 1996/1/10

Y1 - 1996/1/10

N2 - The invention relates to an antibody which inhibits the binding between u-PA and u-PAR to an extent of at least 90% in an assay as defined in the specification, or an active fragment or immunological equivalent of said antibody. Examples of such antibodies are deposited 7 July 1994 at Deutsche Sammlung von Mikroorganismen und Zellkulturen (DSM) with accession numbers DSM ACC2178 and DSM ACC2179 under the terms and conditions of the Budapest Treaty. The invention furthermore relates to a method for detecting or quantifying u-PAR or a glycosylation variant of u-PAR in a sample by use of an antibody according to the invention. Furthermore, the invention relates to a method for the manufacture of a therapeutic agent for preventing or counteracting localized proteolytic activity using of an antibody of the invention as well as to use of an antibody according to the invention for the preparation of a diagnostic agent which is capable of targeting a diagnostic to a cell that contains a u-PAR on the surface.

AB - The invention relates to an antibody which inhibits the binding between u-PA and u-PAR to an extent of at least 90% in an assay as defined in the specification, or an active fragment or immunological equivalent of said antibody. Examples of such antibodies are deposited 7 July 1994 at Deutsche Sammlung von Mikroorganismen und Zellkulturen (DSM) with accession numbers DSM ACC2178 and DSM ACC2179 under the terms and conditions of the Budapest Treaty. The invention furthermore relates to a method for detecting or quantifying u-PAR or a glycosylation variant of u-PAR in a sample by use of an antibody according to the invention. Furthermore, the invention relates to a method for the manufacture of a therapeutic agent for preventing or counteracting localized proteolytic activity using of an antibody of the invention as well as to use of an antibody according to the invention for the preparation of a diagnostic agent which is capable of targeting a diagnostic to a cell that contains a u-PAR on the surface.

M3 - Patent

M1 - EP0691350

ER -

ID: 178221496