Unpredictability of regression of analgesia during the continuous postoperative extradural infusion of bupivacaine.

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Standard

Unpredictability of regression of analgesia during the continuous postoperative extradural infusion of bupivacaine. / Mogensen, T; Hjortsø, N C; Bigler, D; Lund, Claus; Kehlet, H.

I: British Journal of Anaesthesia, Bind 60, Nr. 5, 1988, s. 515-519.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning

Harvard

Mogensen, T, Hjortsø, NC, Bigler, D, Lund, C & Kehlet, H 1988, 'Unpredictability of regression of analgesia during the continuous postoperative extradural infusion of bupivacaine.', British Journal of Anaesthesia, bind 60, nr. 5, s. 515-519. <http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=3377927&query_hl=54>

APA

Mogensen, T., Hjortsø, N. C., Bigler, D., Lund, C., & Kehlet, H. (1988). Unpredictability of regression of analgesia during the continuous postoperative extradural infusion of bupivacaine. British Journal of Anaesthesia, 60(5), 515-519. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=3377927&query_hl=54

Vancouver

Mogensen T, Hjortsø NC, Bigler D, Lund C, Kehlet H. Unpredictability of regression of analgesia during the continuous postoperative extradural infusion of bupivacaine. British Journal of Anaesthesia. 1988;60(5):515-519.

Author

Mogensen, T ; Hjortsø, N C ; Bigler, D ; Lund, Claus ; Kehlet, H. / Unpredictability of regression of analgesia during the continuous postoperative extradural infusion of bupivacaine. I: British Journal of Anaesthesia. 1988 ; Bind 60, Nr. 5. s. 515-519.

Bibtex

@article{3b737dd2d742433e8a0733da6f8df4d9,
title = "Unpredictability of regression of analgesia during the continuous postoperative extradural infusion of bupivacaine.",
abstract = "Twenty-four otherwise healthy patients scheduled for elective major abdominal surgery received general anaesthesia plus lumbar extradural analgesia. A loading dose of 0.5% plain bupivacaine was given to produce sensory analgesia (pin prick) from T4 to S5 and followed by a continuous infusion of 0.5% plain bupivacaine 8 ml h-1. Pain, scored on a 5-point scale, and sensory analgesia were assessed hourly for 16 h after skin incision. If sensory analgesia decreased by more than 5 segments from its preoperative level, or if the pain score reached 2 (moderate pain), the patients were removed from the study, and pain was treated otherwise. Only three patients maintained their initial levels of sensory analgesia and a pain score of less than 2. In the remaining patients sensory analgesia decreased at least 5 segments or pain score reached 2 between 4 and 16 h after skin incision. We found a weak correlation between increasing age and the duration of sensory analgesia (r = 0.46, P less than 0.05), but no significant correlations between duration of sensory analgesia and sex, weight, height, body surface area, serum albumin concentration, duration or site of operation.",
author = "T Mogensen and Hjorts{\o}, {N C} and D Bigler and Claus Lund and H Kehlet",
year = "1988",
language = "English",
volume = "60",
pages = "515--519",
journal = "British Journal of Anaesthesia",
issn = "0007-0912",
publisher = "Oxford University Press",
number = "5",

}

RIS

TY - JOUR

T1 - Unpredictability of regression of analgesia during the continuous postoperative extradural infusion of bupivacaine.

AU - Mogensen, T

AU - Hjortsø, N C

AU - Bigler, D

AU - Lund, Claus

AU - Kehlet, H

PY - 1988

Y1 - 1988

N2 - Twenty-four otherwise healthy patients scheduled for elective major abdominal surgery received general anaesthesia plus lumbar extradural analgesia. A loading dose of 0.5% plain bupivacaine was given to produce sensory analgesia (pin prick) from T4 to S5 and followed by a continuous infusion of 0.5% plain bupivacaine 8 ml h-1. Pain, scored on a 5-point scale, and sensory analgesia were assessed hourly for 16 h after skin incision. If sensory analgesia decreased by more than 5 segments from its preoperative level, or if the pain score reached 2 (moderate pain), the patients were removed from the study, and pain was treated otherwise. Only three patients maintained their initial levels of sensory analgesia and a pain score of less than 2. In the remaining patients sensory analgesia decreased at least 5 segments or pain score reached 2 between 4 and 16 h after skin incision. We found a weak correlation between increasing age and the duration of sensory analgesia (r = 0.46, P less than 0.05), but no significant correlations between duration of sensory analgesia and sex, weight, height, body surface area, serum albumin concentration, duration or site of operation.

AB - Twenty-four otherwise healthy patients scheduled for elective major abdominal surgery received general anaesthesia plus lumbar extradural analgesia. A loading dose of 0.5% plain bupivacaine was given to produce sensory analgesia (pin prick) from T4 to S5 and followed by a continuous infusion of 0.5% plain bupivacaine 8 ml h-1. Pain, scored on a 5-point scale, and sensory analgesia were assessed hourly for 16 h after skin incision. If sensory analgesia decreased by more than 5 segments from its preoperative level, or if the pain score reached 2 (moderate pain), the patients were removed from the study, and pain was treated otherwise. Only three patients maintained their initial levels of sensory analgesia and a pain score of less than 2. In the remaining patients sensory analgesia decreased at least 5 segments or pain score reached 2 between 4 and 16 h after skin incision. We found a weak correlation between increasing age and the duration of sensory analgesia (r = 0.46, P less than 0.05), but no significant correlations between duration of sensory analgesia and sex, weight, height, body surface area, serum albumin concentration, duration or site of operation.

M3 - Journal article

VL - 60

SP - 515

EP - 519

JO - British Journal of Anaesthesia

JF - British Journal of Anaesthesia

SN - 0007-0912

IS - 5

ER -

ID: 40176278