Underlying Mechanisms of the Protective Effects of Lifestyle Factors in the Prevention of Age-Related Diseases
Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
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Underlying Mechanisms of the Protective Effects of Lifestyle Factors in the Prevention of Age-Related Diseases. / Alcaráz, Nicolás; Salcedo-Tello, Pamela; González-Barrios, Rodrigo; Torres-Arciga, Karla; Guzmán-Ramos, Kioko.
I: Archives of Medical Research, Bind 55, Nr. 5, 103014, 2024.Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
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TY - JOUR
T1 - Underlying Mechanisms of the Protective Effects of Lifestyle Factors in the Prevention of Age-Related Diseases
AU - Alcaráz, Nicolás
AU - Salcedo-Tello, Pamela
AU - González-Barrios, Rodrigo
AU - Torres-Arciga, Karla
AU - Guzmán-Ramos, Kioko
N1 - Publisher Copyright: © 2024
PY - 2024
Y1 - 2024
N2 - The rise in life expectancy has significantly increased the occurrence of age-related chronic diseases, leading to escalating expenses for both society and individuals. Among the main factors influencing health and lifespan, lifestyle takes a forefront position. Specifically, nutrition, mental activity, and physical exercise influence the molecular and functional mechanisms that contribute to the prevention of major age-related diseases. Gaining deeper insights into the mechanisms that drive the positive effects of healthy lifestyles is valuable for creating interventions to prevent or postpone the development of chronic degenerative diseases. This review summarizes the main mechanisms that underlie the positive effect of lifestyle factors in counteracting the major age-related diseases involving brain health, musculoskeletal function, cancer, frailty, and cardiovascular diseases, among others. This knowledge will help to identify high-risk populations for targeted intervention trials and discover new biomarkers associated with healthy aging.
AB - The rise in life expectancy has significantly increased the occurrence of age-related chronic diseases, leading to escalating expenses for both society and individuals. Among the main factors influencing health and lifespan, lifestyle takes a forefront position. Specifically, nutrition, mental activity, and physical exercise influence the molecular and functional mechanisms that contribute to the prevention of major age-related diseases. Gaining deeper insights into the mechanisms that drive the positive effects of healthy lifestyles is valuable for creating interventions to prevent or postpone the development of chronic degenerative diseases. This review summarizes the main mechanisms that underlie the positive effect of lifestyle factors in counteracting the major age-related diseases involving brain health, musculoskeletal function, cancer, frailty, and cardiovascular diseases, among others. This knowledge will help to identify high-risk populations for targeted intervention trials and discover new biomarkers associated with healthy aging.
KW - Age-related diseases
KW - Brain health
KW - Healthy aging
KW - Healthy diet
KW - Lifestyle factors
KW - Physical activity
U2 - 10.1016/j.arcmed.2024.103014
DO - 10.1016/j.arcmed.2024.103014
M3 - Review
C2 - 38861840
AN - SCOPUS:85195379473
VL - 55
JO - Archives of Medical Research
JF - Archives of Medical Research
SN - 0188-4409
IS - 5
M1 - 103014
ER -
ID: 395391258