Type XXIII collagen
Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › fagfællebedømt
Type XXIII collagen is a type II transmembrane collagen found in healthy human and mouse tissues of the lung, cornea, skin, tendon, amnion, and to a lesser extent in the kidney and placenta. Currently, its function is unknown; however, type XXIII collagen is a component of many epithelia and expressed on epithelial cell surfaces, suggesting a role in the formation or maintenance of cell-cell contacts or the polarization of epithelial cells. Type XXIII collagen levels in patient samples have been proposed as a new biomarker of prostate cancer progression and recurrence. Type XXIII collagen has been detected in urine samples of prostate cancer and non-small-cell lung cancer patients and can discriminate between controls and cancer patients, indicating a potential role as a new diagnostic tool in certain types of cancer. There are currently no mutations in humans or mice associated with biological functions; no biomarkers have been put forward.
Originalsprog | Engelsk |
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Titel | Biochemistry of Collagens, Laminins and Elastin : Structure, Function and Biomarkers |
Antal sider | 4 |
Forlag | Elsevier |
Publikationsdato | 2024 |
Udgave | 3 |
Sider | 199-202 |
Kapitel | 23 |
ISBN (Trykt) | 9780443156182 |
ISBN (Elektronisk) | 9780443156175 |
DOI | |
Status | Udgivet - 2024 |
Bibliografisk note
Publisher Copyright:
© 2024 Elsevier Inc. All rights reserved.
ID: 391158875