Treatment of serious urological infections with cefotaxime compared to ampicillin plus netilmicin
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Treatment of serious urological infections with cefotaxime compared to ampicillin plus netilmicin. / Rasmussen, D; Bremmelgaard, A; Rasmussen, F; Thorup, Jørgen Mogens.
I: Danish Medical Bulletin, Bind 33, Nr. 1, 02.1986, s. 49-51.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Treatment of serious urological infections with cefotaxime compared to ampicillin plus netilmicin
AU - Rasmussen, D
AU - Bremmelgaard, A
AU - Rasmussen, F
AU - Thorup, Jørgen Mogens
PY - 1986/2
Y1 - 1986/2
N2 - Fifty-nine patients with severe urinary tract infections were treated with either cefotaxime or ampicillin plus netilmicin in a controlled, open randomised study of the clinical and bacteriological effects. The patients responded favourably in both groups. The minimum inhibitory concentrations of cefotaxime against the isolates from blood were low for all bacterial strains except one (Streptococcus faecalis). Time to normalisation of temperature was significantly shorter in the cefotaxime group. The results suggest that cefotaxime is an effective and well-tolerated agent in the treatment of serious infections. However, the difference between the two groups was too small to allow preference of one procedure over the other.
AB - Fifty-nine patients with severe urinary tract infections were treated with either cefotaxime or ampicillin plus netilmicin in a controlled, open randomised study of the clinical and bacteriological effects. The patients responded favourably in both groups. The minimum inhibitory concentrations of cefotaxime against the isolates from blood were low for all bacterial strains except one (Streptococcus faecalis). Time to normalisation of temperature was significantly shorter in the cefotaxime group. The results suggest that cefotaxime is an effective and well-tolerated agent in the treatment of serious infections. However, the difference between the two groups was too small to allow preference of one procedure over the other.
KW - Ampicillin
KW - Cefotaxime
KW - Drug Therapy, Combination
KW - Female
KW - Humans
KW - Male
KW - Middle Aged
KW - Netilmicin
KW - Sepsis
KW - Surgical Wound Infection
KW - Urinary Tract Infections
M3 - Journal article
C2 - 3948539
VL - 33
SP - 49
EP - 51
JO - Danish Medical Journal
JF - Danish Medical Journal
SN - 2245-1919
IS - 1
ER -
ID: 47629595