T-lymphocyte subsets in recurrent aphthous ulceration
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T-lymphocyte subsets in recurrent aphthous ulceration. / Pedersen, A; Klausen, B; Hougen, H P; Stenvang, J P.
I: Journal of Oral Pathology & Medicine, Bind 18, Nr. 1, 01.1989, s. 59-60.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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T1 - T-lymphocyte subsets in recurrent aphthous ulceration
AU - Pedersen, A
AU - Klausen, B
AU - Hougen, H P
AU - Stenvang, J P
PY - 1989/1
Y1 - 1989/1
N2 - Peripheral T-lymphocyte subsets: T-helper (OKT4) and T-suppressor (OKT8) cells were studied quantitatively in 20 patients with recurrent aphthous ulceration (RAU) in ulcerative, as well as inactive, stages of the disease. The figures were compared with T-lymphocyte subsets from matched control donors with no history of RAU. The ratio of T-helper: T-suppressor cells was significantly lower in both stages in the patients compared with controls due to a significantly increased number of T-suppressor cells in RAU patients. The number of T-helper cells in the patients did not differ significantly in either stage compared with controls. The study support the hypothesis of recurrent aphthous ulceration being a disorder of immunodeficiency.
AB - Peripheral T-lymphocyte subsets: T-helper (OKT4) and T-suppressor (OKT8) cells were studied quantitatively in 20 patients with recurrent aphthous ulceration (RAU) in ulcerative, as well as inactive, stages of the disease. The figures were compared with T-lymphocyte subsets from matched control donors with no history of RAU. The ratio of T-helper: T-suppressor cells was significantly lower in both stages in the patients compared with controls due to a significantly increased number of T-suppressor cells in RAU patients. The number of T-helper cells in the patients did not differ significantly in either stage compared with controls. The study support the hypothesis of recurrent aphthous ulceration being a disorder of immunodeficiency.
KW - Adolescent
KW - Adult
KW - Aged
KW - Female
KW - Humans
KW - Leukocyte Count
KW - Male
KW - Middle Aged
KW - Recurrence
KW - Stomatitis, Aphthous
KW - T-Lymphocytes
KW - T-Lymphocytes, Helper-Inducer
KW - T-Lymphocytes, Regulatory
M3 - Journal article
C2 - 2526218
VL - 18
SP - 59
EP - 60
JO - Journal of Oral Pathology and Medicine
JF - Journal of Oral Pathology and Medicine
SN - 0904-2512
IS - 1
ER -
ID: 44515047