Synthesis of deoxycytidine oligomers containing phosphorodithioate linkages
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Synthesis of deoxycytidine oligomers containing phosphorodithioate linkages. / Grandas, Ana; Marshall, William S.; Nielsen, John; Caruthers, Marvin H.
I: Tetrahedron Letters, Bind 30, Nr. 5, 01.01.1989, s. 543-546.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Synthesis of deoxycytidine oligomers containing phosphorodithioate linkages
AU - Grandas, Ana
AU - Marshall, William S.
AU - Nielsen, John
AU - Caruthers, Marvin H.
PY - 1989/1/1
Y1 - 1989/1/1
N2 - Deoxydicytidine phosphoramidite, 4-chlorobenzylmercaptan and tetrazole reacted to form dinucleoside thiophosphite. Oxidation with sulfur yields phosphorodithioates which were used to synthesize pentadecadeoxyoligonucleotides containing nuclease resistant phosphorodithioate internucleotide linkages.
AB - Deoxydicytidine phosphoramidite, 4-chlorobenzylmercaptan and tetrazole reacted to form dinucleoside thiophosphite. Oxidation with sulfur yields phosphorodithioates which were used to synthesize pentadecadeoxyoligonucleotides containing nuclease resistant phosphorodithioate internucleotide linkages.
U2 - 10.1016/S0040-4039(00)95248-1
DO - 10.1016/S0040-4039(00)95248-1
M3 - Journal article
AN - SCOPUS:0024529880
VL - 30
SP - 543
EP - 546
JO - Tetrahedron Letters
JF - Tetrahedron Letters
SN - 0040-4039
IS - 5
ER -
ID: 131117450