Structural characteristics of an antigen required for its interaction with Ia and recognition by T cells

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Standard

Structural characteristics of an antigen required for its interaction with Ia and recognition by T cells. / Sette, A; Buus, S; Colon, S; Smith, J A; Miles, C; Grey, H M.

I: Nature, Bind 328, Nr. 6129, 1987, s. 395-9.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Sette, A, Buus, S, Colon, S, Smith, JA, Miles, C & Grey, HM 1987, 'Structural characteristics of an antigen required for its interaction with Ia and recognition by T cells', Nature, bind 328, nr. 6129, s. 395-9. https://doi.org/10.1038/328395a0

APA

Sette, A., Buus, S., Colon, S., Smith, J. A., Miles, C., & Grey, H. M. (1987). Structural characteristics of an antigen required for its interaction with Ia and recognition by T cells. Nature, 328(6129), 395-9. https://doi.org/10.1038/328395a0

Vancouver

Sette A, Buus S, Colon S, Smith JA, Miles C, Grey HM. Structural characteristics of an antigen required for its interaction with Ia and recognition by T cells. Nature. 1987;328(6129):395-9. https://doi.org/10.1038/328395a0

Author

Sette, A ; Buus, S ; Colon, S ; Smith, J A ; Miles, C ; Grey, H M. / Structural characteristics of an antigen required for its interaction with Ia and recognition by T cells. I: Nature. 1987 ; Bind 328, Nr. 6129. s. 395-9.

Bibtex

@article{857c9e70ebce11ddbf70000ea68e967b,
title = "Structural characteristics of an antigen required for its interaction with Ia and recognition by T cells",
abstract = "A detailed analysis of the residues within an immunogenic peptide that endow it with the capacity to interact with Ia and to be recognized by T cells is presented. Ia interacts with only a few of the peptide residues and overall exhibits a very broad specificity. Some residues appear to interact both with Ia and with T cells, leading to a model in which a peptide antigen is 'sandwiched' between Ia and the T-cell receptor.",
author = "A Sette and S Buus and S Colon and Smith, {J A} and C Miles and Grey, {H M}",
note = "Keywords: Amino Acid Sequence; Animals; Antigens; Binding, Competitive; Histocompatibility Antigens Class II; Hybridomas; Ovalbumin; Peptide Fragments; Peptides; Structure-Activity Relationship; T-Lymphocytes",
year = "1987",
doi = "10.1038/328395a0",
language = "English",
volume = "328",
pages = "395--9",
journal = "Nature",
issn = "0028-0836",
publisher = "nature publishing group",
number = "6129",

}

RIS

TY - JOUR

T1 - Structural characteristics of an antigen required for its interaction with Ia and recognition by T cells

AU - Sette, A

AU - Buus, S

AU - Colon, S

AU - Smith, J A

AU - Miles, C

AU - Grey, H M

N1 - Keywords: Amino Acid Sequence; Animals; Antigens; Binding, Competitive; Histocompatibility Antigens Class II; Hybridomas; Ovalbumin; Peptide Fragments; Peptides; Structure-Activity Relationship; T-Lymphocytes

PY - 1987

Y1 - 1987

N2 - A detailed analysis of the residues within an immunogenic peptide that endow it with the capacity to interact with Ia and to be recognized by T cells is presented. Ia interacts with only a few of the peptide residues and overall exhibits a very broad specificity. Some residues appear to interact both with Ia and with T cells, leading to a model in which a peptide antigen is 'sandwiched' between Ia and the T-cell receptor.

AB - A detailed analysis of the residues within an immunogenic peptide that endow it with the capacity to interact with Ia and to be recognized by T cells is presented. Ia interacts with only a few of the peptide residues and overall exhibits a very broad specificity. Some residues appear to interact both with Ia and with T cells, leading to a model in which a peptide antigen is 'sandwiched' between Ia and the T-cell receptor.

U2 - 10.1038/328395a0

DO - 10.1038/328395a0

M3 - Journal article

C2 - 3497349

VL - 328

SP - 395

EP - 399

JO - Nature

JF - Nature

SN - 0028-0836

IS - 6129

ER -

ID: 9947780